Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors

Steroids

Volumn 77, Issue 5, 2012, Pages 441-447

  Ji, Long ^a   Yuan, Yonglei ^a   Luo, Liping ^a   Chen, Zhe ^c   Ma, Xiaoqiong ^c   Ma, Zhongjun ^a   Cheng, Lin ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b Zhejiang Academy of Traditional Chinese Medicine   (China)

^c Chinese Traditional Medicine Hospital of Zhejiang Province   (China)

Author keywords

Anti inflammation; Glutathione; I B kinase ; Michael reaction acceptors; Physalins; UPLC ESI MS MS analysis

Indexed keywords

ANTIINFLAMMATORY AGENT; CYSTEINE; GLUTATHIONE; HYDROCORTISONE; I KAPPA B KINASE BETA; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOPHYSALIN A; LIPOPOLYSACCHARIDE; MICHAEL REACTION ACCEPTOR; NITRIC OXIDE; PHYSALIN A; PHYSALIN G; PHYSALIN L; PHYSALIN O; PLANT EXTRACT; RECOMBINANT PROTEIN; STEROID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CHINA; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; DRUG TARGETING; EXTRACTION; MACROPHAGE; MICHAEL ADDITION; MONOCYTE; MOUSE; NONHUMAN; PHYSALIS; PHYSALIS ALKEKENGI; PHYTOCHEMISTRY; PLANT; PROTON NUCLEAR MAGNETIC RESONANCE; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ALKYLATION; ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; GLUTATHIONE; HUMANS; I-KAPPA B KINASE; LIPOPOLYSACCHARIDES; MACROPHAGES; MASS SPECTROMETRY; MICE; MOLECULAR STRUCTURE; NITRIC OXIDE; PHYSALIS; PHYTOSTEROLS; SECOSTEROIDS;

PHYSALIS ALKEKENGI;

EID: 84862820812     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2011.11.016     Document Type: Article

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