Mcl-1 determines the imiquimod-induced apoptosis but not imiquimod-induced autophagy in skin cancer cells

Journal of Dermatological Science

Volumn 65, Issue 3, 2012, Pages 170-178

  Huang, Shi Wei ^a   Chang, Chia Che ^a   Lin, Chi Chen ^a,b   Tsai, Jaw Ji ^a,b   Chen, Yi Ju ^b   Wu, Chun Ying ^b   Liu, Kuang Ting ^c   Shieh, Jeng Jer ^a,b  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c TAOYUAN ARMED FORCES GENERAL HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Autophagy; Basal cell carcinoma; Imiquimod; Mcl 1; Skin cancer cells

Indexed keywords

3 METHYLADENINE; ACRIDINE ORANGE; BAFILOMYCIN A1; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE INHIBITOR; CYCLOHEXIMIDE; ENHANCED GREEN FLUORESCENT PROTEIN; IMIQUIMOD; INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN 1; MESSENGER RNA; PROTEASOME INHIBITOR; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CONTROLLED STUDY; DNA CONTENT; DOWN REGULATION; DRUG MECHANISM; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSLATION; SKIN CANCER;

AMINOQUINOLINES; APOPTOSIS; AUTOPHAGY; BCL-X PROTEIN; CARCINOMA, BASAL CELL; CELL LINE, TUMOR; DOWN-REGULATION; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; SKIN NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 84862818651     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2011.11.001     Document Type: Article

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