Umbilical cord stem cells released from alginate-fibrin microbeads inside macroporous and biofunctionalized calcium phosphate cement for bone regeneration

Acta Biomaterialia

Volumn 8, Issue 6, 2012, Pages 2297-2306

  Chen, Wenchuan ^a,b   Zhou, Hongzhi ^a,c   Weir, Michael D ^a   Bao, Chongyun ^b   Xu, Hockin H K ^a,d,e  

^a UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^b SICHUAN UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e University of Marylandw Baltimore County   (United States)

Author keywords

Arginine glycine aspartic acid; Biofunctionalized calcium phosphate cement; Fibronectin; Gas foaming porogen; Human umbilical cord stem cells

Indexed keywords

ALGINATE; ARGININE; BONE; CEMENTS; MINERALS; PHOSPHATASES; STEM CELLS; TISSUE ENGINEERING;

ARGININE-GLYCINE-ASPARTIC ACIDS; BIOFUNCTIONALIZED CALCIUM PHOSPHATE CEMENT; CALCIUM PHOSPHATE CEMENT; GAS-FOAMING POROGEN; HUMAN UMBILICAL CORD; HUMAN UMBILICAL CORD STEM CELL; MESENCHYMAL STEM CELL; MICROBEADS; POROGENS; UMBILICAL CORD STEM CELLS;

CELL CULTURE;

ALGINIC ACID; ALKALINE PHOSPHATASE; ARGINYLGLYCYLASPARTIC ACID; BONE CEMENT; CALCIUM PHOSPHATE; CHITOSAN; COLLAGEN TYPE 1; FIBRIN; FIBRONECTIN; OSTEOCALCIN;

ARTICLE; BONE DEVELOPMENT; BONE MINERAL; BONE REGENERATION; BONE STRENGTH; BONE TISSUE; CANCELLOUS BONE; CELL DENSITY; CELL DIFFERENTIATION; CELL FUNCTION; CELL LINEAGE; CELL PROLIFERATION; CONTROLLED STUDY; ENCAPSULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; POROSITY; POWDER; PRIORITY JOURNAL; STEM CELL; TISSUE ENGINEERING; UMBILICAL CORD STEM CELL;

EID: 84862817120     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.02.021     Document Type: Article

References (61)

1. J.J. Mao, G. Vunjak-Novakovic, A.G. Mikos, and A. Atala Regenerative medicine: translational approaches and tissue engineering 2007 Artech House Boston, MA [Chapters 1-3]
2. M. Bohner Design of ceramic-based cements and putties for bone graft substitution Eur Cell Mater 20 2010 1 12
3. World Health Organization. The burden of musculoskeletal conditions at the start of the new millennium. Technical report series 919. Geneva, Switzerland: WHO; 2003. p. 102-3.
4. A.J. Salgado, O.P. Coutinho, and R.L. Reis Bone tissue engineering: state of the art and future trends Macromol Biosci 4 2004 743 765
5. M. Bohner, and G. Baroud Injectability of calcium phosphate pastes Biomaterials 26 2005 1553 1563
6. M.P. Ginebra, T. Traykova, and J.A. Planell Calcium phosphate cements as bone drug-delivery systems: a review J Control Release 113 2006 102 110
7. D.S. Benoit, C.R. Nuttelman, S.D. Collins, and K.S. Anseth Synthesis and characterization of a fluvastatin-releasing hydrogel delivery system to modulate hMSC differentiation and function for bone regeneration Biomaterials 27 2006 6102 6110
8. J.J. Mao, W.V. Giannobile, J.A. Helms, S.J. Hollister, P.H. Krebsbach, and M.T. Longaker Craniofacial tissue engineering by stem cells J Dent Res 85 2006 966 979
9. P.C. Johnson, A.G. Mikos, J.P. Fisher, and J.A. Jansen Strategic directions in tissue engineering Tissue Eng 13 2007 2827 2837
10. P. Habibovic, U. Gbureck, C.J. Doillon, D.C. Bassett, C.A. van Blitterswijk, and J.E. Barralet Osteoconduction and osteoinduction of low-temperature 3D printed bioceramic implants Biomaterials 29 2008 944 953
11. H.S. Wang, S.C. Hung, S.T. Peng, C.C. Huang, H.M. Wei, and Y.J. Guo Mesenchymal stem cells in the Whartons jelly of the human umbilical cord Stem Cells 22 2004 1330 1337
12. D. Baksh, R. Yao, and R.S. Tuan Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow Stem Cells 25 2007 1384 1392
13. M.M. Bailey, L. Wang, C.J. Bode, K.E. Mitchell, and M.S. Detamore A comparison of human umbilical cord matrix stem cells and temporomandibular joint condylar chondrocytes for tissue engineering temporomandibular joint condylar cartilage Tissue Eng 13 2007 2003 2010
14. A. Can, and S. Karahuseyinoglu Concise review. Human umbilical cord stroma with regard to the source of fetus-derived stem cells Stem Cells 25 2007 2886 2895
15. L. Wang, M. Singh, L.F. Bonewald, and M.S. Detamore Signalling strategies for osteogenic differentiation of human umbilical cord mesenchymal stromal cells for 3D bone tissue engineering J Tissue Eng Regen Med 3 2009 398 404
16. L. Zhao, M.D. Weir, and H.H.K. Xu An injectable calcium phosphate-alginate hydrogel-umbilical cord mesenchymal stem cell paste for bone tissue engineering Biomaterials 31 2010 6502 6510
17. S. Foppiano, S.J. Marshall, G.W. Marshall, E. Saiz, and A.P. Tomsia The influence of novel bioactive glasses on in vitro osteoblast behavior J Biomed Mater Res A 71 2004 242 249
18. S. Deville, E. Saiz, R.K. Nalla, and A.P. Tomsia Freezing as a path to build complex composites Science 311 2006 515 518
19. G.C. Reilly, S. Radin, A.T. Chen, and P. Ducheyne Differential alkaline phosphatase responses of rat and human bone marrow derived mesenchymal stem cells to 45S5 bioactive glass Biomaterials 28 2007 4091 4097
20. P. Kasten, I. Beyen, P. Niemeyer, R. Luginbuhl, M. Bohner, and W. Richter Porosity and pore size of beta-tricalcium phosphate scaffold can influence protein production and osteogenic differentiation of human mesenchymal stem cells: an in vitro and in vivo study Acta Biomater 4 2008 1904 1915
21. M.P. Ginebra, A. Rilliard, E. Fernández, C. Elvira, J.S. Román, and J.A. Planell Mechanical and rheological improvement of a calcium phosphate cement by the addition of a polymeric drug J Biomed Mater Res 57 2001 113 118
22. J.E. Barralet, T. Gaunt, A.J. Wright, I.R. Gibson, and J.C. Knowles Effect of porosity reduction by compaction on compressive strength and microstructure of calcium phosphate cement J Biomed Mater Res B 63 2002 1 9
23. M.P. Ginebra, F.C. Driessens, and J.A. Planell Effect of the particle size on the micro and nanostructural features of a calcium phosphate cement: a kinetic analysis Biomaterials 25 2004 3453 3462
24. M. Bohner, U. Gbureck, and J.E. Barralet Technological issues for the development of more efficient calcium phosphate bone cements: a critical assessment Biomaterials 26 2005 6423 6429
25. J.A. Jansen, J.W. Vehof, P.Q. Ruhe, H. Kroeze-Deutman, Y. Kuboki, and H. Takita Growth factor-loaded scaffolds for bone engineering J Control Release 101 2005 127 136
26. W.E. Brown, and L.C. Chow A new calcium phosphate water setting cement P.W. Brown, Cements research progress 1986 American Ceramic Society Westerville, OH 352 379
27. C.D. Friedman, P.D. Costantino, S. Takagi, and L.C. Chow Bone source hydroxyapatite cement: a novel biomaterial for craniofacial skeletal tissue engineering and reconstruction J Biomed Mater Res 43 1998 428 432
28. H. Zhou, and H.H.K. Xu The fast release of stem cells from alginate-fibrin microbeads in injectable scaffolds for bone tissue engineering Biomaterials 32 2011 7503 7513
29. S. Hesaraki, A. Zamanian, and F. Moztarzadeh The influence of the acidic component of the gas-foaming porogen used in preparing an injectable porous calcium phosphate cement on its properties: acetic acid versus citric acid J Biomed Mater Res B 86 2008 208 216
30. Chen WC, Zhou HZ, Tang MH, Weir MD, Bao CY, Xu HHK. Gas-foaming calcium phosphate cement scaffold encapsulating human umbilical cord stem cells. Tissue Eng Part A, in press. http://dx.doi.org/10.1089/ten.tea.2011.0267.
31. M.D. Weir, H.H.K. Xu, and C.G. Simon Strong calcium phosphate cement-chitosan-mesh construct containing cell-encapsulating hydrogel beads for bone tissue engineering J Biomed Mater Res A 77 2006 487 496
32. K.H. Bouhadir, K.Y. Lee, E. Alsberg, K.L. Damm, K.W. Anderson, and D.J. Mooney Degradation of partially oxidized alginate and its potential application for tissue engineering Biotechnol Prog 17 2001 945 950
33. H.H.K. Xu, S. Takagi, J.B. Quinn, and L.C. Chow Fast-setting calcium phosphate scaffolds with tailored macropore formation rates for bone regeneration J Biomed Mater Res A 68 2004 725 734
34. J. Rouwkema, N.C. Rivron, and C.A. van Blitterswijk Vascularization in tissue engineering Trends Biotechnol 26 2008 434 441
35. M. Lovett, K. Lee, A. Edwards, and D.L. Kaplan Vascularization strategies for tissue engineering Tissue Eng Part B: Rev 15 2009 353 370
36. X. Shi, B. Sitharaman, Q.P. Pham, F. Liang, K. Wu, and B.W. Edward Fabrication of porous ultra-short single-walled carbon nanotube nanocomposite scaffolds for bone tissue engineering Biomaterials 28 2007 4078 4090
37. C.K. Kuo, and P.X. Ma Ionically crosslinked alginate hydrogels as scaffolds for tissue engineering: Part 1. Structure, gelation rate and mechanical properties Biomaterials 22 2001 511 521
38. J.L. Drury, R.G. Dennis, and D.J. Mooney The tensile properties of alginate hydrogels Biomaterials 25 2004 3187 3199
39. C.J. Damien, and J.R. Parsons Bone graft and bone graft substitutes: a review of current technology and applications J Appl Biomater 2 1991 187 208
40. D.P. Link, J. den Dolder, J.G. Wolke, and J.A. Jansen The cytocompatibility and early osteogenic characteristics of an injectable calcium phosphate cement Tissue Eng 13 2007 493 500
41. M.D. Weir, and H.H.K. Xu Culture human mesenchymal stem cells with calcium phosphate cement scaffolds for bone repair J Biomed Mater Res B 93 2010 93 105
42. Y. Sogo, A. Ito, T. Matsuno, A. Oyane, G. Tamazawa, and T. Satoh Fibronectin-calcium phosphate composite layer on hydroxyapatite to enhance adhesion, cell spread and osteogenic differentiation of human mesenchymal stem cells in vitro Biomed Mater 2 2007 116 123
43. W. Schneiders, A. Reinstorf, W. Pompe, R. Grass, A. Biewener, and M. Holch Effect of modification of hydroxyapatite/collagen composites with sodium citrate, phosphoserine, phosphoserine/RGD-peptide and calcium carbonate on bone remodelling Bone 40 2007 1048 1059
44. C.R. Nuttelman, D.J. Mortisen, S.M. Henry, and K.S. Anseth Attachment of fibronectin to poly(vinyl alcohol) hydrogels promotes NIH3T3 cell adhesion, proliferation, and migration J Biomed Mater Res 57 2001 217 223
45. B.H. Schonmeyr, A.K. Wong, S. Li, F. Gewalli, P.G. Cordiero, and B.J. Mehrara Treatment of hydroxyapatite scaffolds with fibronectin and fetal calf serum increases osteoblast adhesion and proliferation in vitro Plast Reconstr Surg 121 2008 751 762
46. C.A. Custodio, C.M. Alves, R.L. Reis, and J.F. Mano Immobilization of fibronectin in chitosan substrates improves cell adhesion and proliferation J Tissue Eng Regen Med 4 2010 316 323
47. S.V. Martyn, H.K. Heywood, P. Rockett, M.D. Paine, M.J. Wang, and P.J. Dobson Electrospray deposited fibronectin retains the ability to promote cell adhesion J Biomed Mater Res B 96 2011 110 118
48. U. Hersel, C. Dahmen, and H. Kessler RGD modified polymers: biomaterials for stimulated cell adhesion and beyond Biomaterials 24 2003 4385 4415
49. S.P. Massia, and J.A. Hubbell Covalent surface immobilization of Arg-Gly-Asp- and Tyr-Ile-Gly-Ser-Arg-containing peptides to obtain well-defined cell-adhesive substrates Anal Biochem 187 1990 292 301
50. Y. Hu, S.R. Winn, I. Krajbich, and J.O. Hollinger Porous polymer scaffolds surface-modified with arginine-glycine-aspartic acid enhance bone cell attachment and differentiation in vitro J Biomed Mater Res A 64 2003 583 590
51. M.C. Durrieu, S. Pallu, F. Guillemot, R. Bareille, J. Amedee, and C.H. Baquey Grafting RGD containing peptides onto hydroxyapatite to promote osteoblastic cells adhesion J Mater Sci Mater Med 15 2004 779 786
52. Y. Huang, J. Ren, T. Ren, S. Gu, Q. Tan, and L. Zhang Bone marrow stromal cells cultured on poly(lactide-co-glycolide)/nano-hydroxyapatite composites with chemical immobilization of Arg-Gly-Asp peptide and preliminary bone regeneration of mandibular defect thereof J Biomed Mater Res A 95 2010 993 1003
53. P. Zhang, H. Wu, H. Wu, Z. Lu, C. Deng, and Z. Hong RGD-conjugated copolymer incorporated into composite of poly(lactide-co-glycotide) and poly(l-lactide)-grafted nanohydroxyapatite for bone tissue engineering Biomacromolecules 12 2011 2667 2680
54. Y. Huang, Q. Luo, X. Li, F. Zhang, and S. Zhao Fabrication and in vitro evaluation of the collagen/hyaluronic acid PEM coating crosslinked with functionalized RGD peptide on titanium Acta Biomater 8 2012 866 877
55. A.A. Sawyer, K.M. Hennessy, and S.L. Bellis Regulation of mesenchymal stem cell attachment and spreading on hydroxyapatite by RGD peptides and adsorbed serum proteins Biomaterials 26 2005 1467 1475
56. P. Schaffner, and M.M. Dard Structure and function of RGD peptides involved in bone biology Cell Mol Life Sci 60 2003 119 132
57. N. Datta, H.L. Holtorf, V.I. Sikavitsas, J.A. Jansen, and A.G. Mikos Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells Biomaterials 26 2005 971 977
58. K. Chatterjee, S. Lin-Gibson, W.E. Wallace, S.H. Parekh, Y.J. Lee, and M.T. Cicerone The effect of 3D hydrogel scaffold modulus on osteoblast differentiation and mineralization revealed by combinatorial screening Biomaterials 31 2010 5051 5062
59. K. Kim, D. Dean, A.G. Mikos, and J.P. Fisher Effect of initial cell seeding density on early osteogenic signal expression of rat bone marrow stromal cells cultured on cross-linked poly(propylene fumarate) disks Biomacromolecules 10 2009 1810 1817
60. F. Yang, C.G. Williams, D.A. Wang, H. Lee, P.N. Manson, and J. Elisseeff The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells Biomaterials 26 2005 5991 5998
61. A.W. Morgan, K.E. Roskov, S. Lin-Gibson, D.L. Kaplan, M.L. Becker, and C.G. Simon Characterization and optimization of RGD-containing silk blends to support osteoblastic differentiation Biomaterials 29 2008 2556 2563