The accumulation of dual pH and temperature responsive micelles in tumors

Biomaterials

Volumn 33, Issue 18, 2012, Pages 4576-4588

  Chen, Yi Chun ^a   Liao, Li Chi ^a   Lu, Pei Lin ^b   Lo, Chun Liang ^c   Tsai, Hsieh Chih ^d   Huang, Chiung Yin ^e   Wei, Kuo Chen ^e   Yen, Tzu Chen ^f   Hsiue, Ging Ho ^a,b  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^e CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^f CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Doxorubicin; EPR effect; PH responsive; Polymeric micelles; Temperature responsive

Indexed keywords

DOXORUBICIN; EPR EFFECT; PH-RESPONSIVE; POLYMERIC MICELLE; TEMPERATURE-RESPONSIVE;

BIODEGRADABLE POLYMERS; BLOCK COPOLYMERS; CELLS; CONJUGATED POLYMERS; DYNAMIC LIGHT SCATTERING; FUNCTIONAL GROUPS; HYDROGELS; PH EFFECTS; TUMORS;

MICELLES;

COPOLYMER; DOXORUBICIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIODEGRADABILITY; BODY TEMPERATURE; CANCER CELL; CANCER INHIBITION; CELL STRAIN MCF 7; CELL VIABILITY; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DISTRIBUTION; DRUG RELEASE; DRUG TARGETING; DRUG UPTAKE; FEMALE; HEAT TREATMENT; HELA CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; LIGHT SCATTERING; MICELLE; MOLECULAR STABILITY; MOUSE; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY; TUMOR;

CALORIMETRY, DIFFERENTIAL SCANNING; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MICELLES; MOLECULAR STRUCTURE; POLYMERS; TEMPERATURE;

EID: 84862812380     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.02.059     Document Type: Article

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