-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A., Bray F., Center M.M., Ferlay J., Ward E., Forman D. Global cancer statistics. CA Cancer J. Clin. 2011, 61:69-90.
-
(2011)
CA Cancer J. Clin.
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
0028324829
-
KAP: a dual specificity phosphatase that interacts with cyclin-dependent kinases
-
Hannon G.J., Casso D., Beach D. KAP: a dual specificity phosphatase that interacts with cyclin-dependent kinases. Proc. Natl. Acad. Sci. USA 1994, 91:1731-1735.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1731-1735
-
-
Hannon, G.J.1
Casso, D.2
Beach, D.3
-
3
-
-
0027437850
-
Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2
-
Gyuris J., Golemis E., Chertkov H., Brent R. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 1993, 75:791-803.
-
(1993)
Cell
, vol.75
, pp. 791-803
-
-
Gyuris, J.1
Golemis, E.2
Chertkov, H.3
Brent, R.4
-
5
-
-
0035990909
-
Structural studies with inhibitors of the cell cycle regulatory kinase cyclin-dependent protein kinase 2
-
Johnson L.N., De Moliner E., Brown N.R., Song H., Barford D., Endicott J.A., Noble M.E. Structural studies with inhibitors of the cell cycle regulatory kinase cyclin-dependent protein kinase 2. Pharmacol. Ther. 2002, 93:113-124.
-
(2002)
Pharmacol. Ther.
, vol.93
, pp. 113-124
-
-
Johnson, L.N.1
De Moliner, E.2
Brown, N.R.3
Song, H.4
Barford, D.5
Endicott, J.A.6
Noble, M.E.7
-
6
-
-
0032146274
-
The regulation of E2F by pRB-family proteins
-
Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev. 1998, 12:2245-2262.
-
(1998)
Genes Dev.
, vol.12
, pp. 2245-2262
-
-
Dyson, N.1
-
7
-
-
0033020484
-
Regulation of endogenous E2F1 stability by the retinoblastoma family proteins
-
Martelli F., Livingston D.M. Regulation of endogenous E2F1 stability by the retinoblastoma family proteins. Proc. Natl. Acad. Sci. USA 1999, 96:2858-2863.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2858-2863
-
-
Martelli, F.1
Livingston, D.M.2
-
8
-
-
79951540345
-
The biochemical basis of CDK phosphorylation-independent regulation of E2F1 by the retinoblastoma protein
-
Cecchini M.J., Dick F.A. The biochemical basis of CDK phosphorylation-independent regulation of E2F1 by the retinoblastoma protein. Biochem. J. 2011, 434:297-308.
-
(2011)
Biochem. J.
, vol.434
, pp. 297-308
-
-
Cecchini, M.J.1
Dick, F.A.2
-
9
-
-
52949093102
-
E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8
-
Morris E.J., Ji J.Y., Yang F., Di Stefano L., Herr A., Moon N.S., Kwon E.J., Haigis K.M., Naar A.M., Dyson N.J. E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8. Nature 2008, 455:552-556.
-
(2008)
Nature
, vol.455
, pp. 552-556
-
-
Morris, E.J.1
Ji, J.Y.2
Yang, F.3
Di Stefano, L.4
Herr, A.5
Moon, N.S.6
Kwon, E.J.7
Haigis, K.M.8
Naar, A.M.9
Dyson, N.J.10
-
10
-
-
33750373155
-
KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction
-
Okamoto K., Kitabayashi I., Taya Y. KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction. Biochem. Biophys. Res. Commun. 2006, 351:216-222.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.351
, pp. 216-222
-
-
Okamoto, K.1
Kitabayashi, I.2
Taya, Y.3
-
11
-
-
0033969884
-
Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression
-
Lee S.W., Reimer C.L., Fang L., Iruela-Arispe M.L., Aaronson S.A. Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression. Mol. Cell Biol. 2000, 20:1723-1732.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 1723-1732
-
-
Lee, S.W.1
Reimer, C.L.2
Fang, L.3
Iruela-Arispe, M.L.4
Aaronson, S.A.5
-
12
-
-
0034282513
-
Aberrant transcripts of the cyclin-dependent kinase-associated protein phosphatase in hepatocellular carcinoma
-
Yeh C.T., Lu S.C., Chen T.C., Peng C.Y., Liaw Y.F. Aberrant transcripts of the cyclin-dependent kinase-associated protein phosphatase in hepatocellular carcinoma. Cancer Res. 2000, 60:4697-4700.
-
(2000)
Cancer Res.
, vol.60
, pp. 4697-4700
-
-
Yeh, C.T.1
Lu, S.C.2
Chen, T.C.3
Peng, C.Y.4
Liaw, Y.F.5
-
13
-
-
74049104750
-
High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer
-
Jiang R., Xia Y., Li J., Deng L., Zhao L., Shi J., Wang X., Sun B. High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer. Int. J. Cancer 2010, 126:1263-1274.
-
(2010)
Int. J. Cancer
, vol.126
, pp. 1263-1274
-
-
Jiang, R.1
Xia, Y.2
Li, J.3
Deng, L.4
Zhao, L.5
Shi, J.6
Wang, X.7
Sun, B.8
-
14
-
-
77951059740
-
The impact of miR-34a on protein output in hepatocellular carcinoma HepG2 cells
-
Cheng J., Zhou L., Xie Q.F., Xie H.Y., Wei X.Y., Gao F., Xing C.Y., Xu X., Li L.J., Zheng S.S. The impact of miR-34a on protein output in hepatocellular carcinoma HepG2 cells. Proteomics 2010, 10:1557-1572.
-
(2010)
Proteomics
, vol.10
, pp. 1557-1572
-
-
Cheng, J.1
Zhou, L.2
Xie, Q.F.3
Xie, H.Y.4
Wei, X.Y.5
Gao, F.6
Xing, C.Y.7
Xu, X.8
Li, L.J.9
Zheng, S.S.10
-
15
-
-
78650809075
-
Identification of histone deacetylase 3 as a biomarker for tumor recurrence following liver transplantation in HBV-associated hepatocellular carcinoma
-
Wu L.M., Yang Z., Zhou L., Zhang F., Xie H.Y., Feng X.W., Wu J., Zheng S.S. Identification of histone deacetylase 3 as a biomarker for tumor recurrence following liver transplantation in HBV-associated hepatocellular carcinoma. PLoS One 2010, 5:e14460.
-
(2010)
PLoS One
, vol.5
-
-
Wu, L.M.1
Yang, Z.2
Zhou, L.3
Zhang, F.4
Xie, H.Y.5
Feng, X.W.6
Wu, J.7
Zheng, S.S.8
-
16
-
-
79961126505
-
NDRG1 as a biomarker for metastasis, recurrence and of poor prognosis in hepatocellular carcinoma
-
Cheng J., Xie H.Y., Xu X., Wu J., Wei X., Su R., Zhang W., Lv Z., Zheng S., Zhou L. NDRG1 as a biomarker for metastasis, recurrence and of poor prognosis in hepatocellular carcinoma. Cancer Lett. 2011, 310:35-45.
-
(2011)
Cancer Lett.
, vol.310
, pp. 35-45
-
-
Cheng, J.1
Xie, H.Y.2
Xu, X.3
Wu, J.4
Wei, X.5
Su, R.6
Zhang, W.7
Lv, Z.8
Zheng, S.9
Zhou, L.10
-
17
-
-
79955836034
-
Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation
-
Yang Z., Zhou L., Wu L.M., Lai M.C., Xie H.Y., Zhang F., Zheng S.S. Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation. Ann. Surg. Oncol. 2011, 18:1243-1250.
-
(2011)
Ann. Surg. Oncol.
, vol.18
, pp. 1243-1250
-
-
Yang, Z.1
Zhou, L.2
Wu, L.M.3
Lai, M.C.4
Xie, H.Y.5
Zhang, F.6
Zheng, S.S.7
-
18
-
-
1642377561
-
ONCOMINE: a cancer microarray database and integrated data-mining platform
-
Rhodes D.R., Yu J., Shanker K., Deshpande N., Varambally R., Ghosh D., Barrette T., Pandey A., Chinnaiyan A.M. ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia 2004, 6:1-6.
-
(2004)
Neoplasia
, vol.6
, pp. 1-6
-
-
Rhodes, D.R.1
Yu, J.2
Shanker, K.3
Deshpande, N.4
Varambally, R.5
Ghosh, D.6
Barrette, T.7
Pandey, A.8
Chinnaiyan, A.M.9
-
19
-
-
34247549347
-
Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma
-
Wurmbach E., Chen Y.B., Khitrov G., Zhang W., Roayaie S., Schwartz M., Fiel I., Thung S., Mazzaferro V., Bruix J., Bottinger E., Friedman S., Waxman S., Llovet J.M. Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma. Hepatology 2007, 45:938-947.
-
(2007)
Hepatology
, vol.45
, pp. 938-947
-
-
Wurmbach, E.1
Chen, Y.B.2
Khitrov, G.3
Zhang, W.4
Roayaie, S.5
Schwartz, M.6
Fiel, I.7
Thung, S.8
Mazzaferro, V.9
Bruix, J.10
Bottinger, E.11
Friedman, S.12
Waxman, S.13
Llovet, J.M.14
-
20
-
-
0035985214
-
Gene expression patterns in human liver cancers
-
Chen X., Cheung S.T., So S., Fan S.T., Barry C., Higgins J., Lai K.M., Ji J., Dudoit S., Ng I.O., Van De Rijn M., Botstein D., Brown P.O. Gene expression patterns in human liver cancers. Mol. Biol. Cell 2002, 13:1929-1939.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 1929-1939
-
-
Chen, X.1
Cheung, S.T.2
So, S.3
Fan, S.T.4
Barry, C.5
Higgins, J.6
Lai, K.M.7
Ji, J.8
Dudoit, S.9
Ng, I.O.10
Van De Rijn, M.11
Botstein, D.12
Brown, P.O.13
-
21
-
-
78650361904
-
A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients
-
Roessler S., Jia H.L., Budhu A., Forgues M., Ye Q.H., Lee J.S., Thorgeirsson S.S., Sun Z., Tang Z.Y., Qin L.X., Wang X.W. A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients. Cancer Res. 2010, 70:10202-10212.
-
(2010)
Cancer Res.
, vol.70
, pp. 10202-10212
-
-
Roessler, S.1
Jia, H.L.2
Budhu, A.3
Forgues, M.4
Ye, Q.H.5
Lee, J.S.6
Thorgeirsson, S.S.7
Sun, Z.8
Tang, Z.Y.9
Qin, L.X.10
Wang, X.W.11
-
22
-
-
64549087538
-
Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma
-
Mas V.R., Maluf D.G., Archer K.J., Yanek K., Kong X., Kulik L., Freise C.E., Olthoff K.M., Ghobrial R.M., McIver P., Fisher R. Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma. Mol. Med. 2009, 15:85-94.
-
(2009)
Mol. Med.
, vol.15
, pp. 85-94
-
-
Mas, V.R.1
Maluf, D.G.2
Archer, K.J.3
Yanek, K.4
Kong, X.5
Kulik, L.6
Freise, C.E.7
Olthoff, K.M.8
Ghobrial, R.M.9
McIver, P.10
Fisher, R.11
-
23
-
-
66049144026
-
Meta analysis of gene expression data within and across species
-
Fierro A.C., Vandenbussche F., Engelen K., Van de Peer Y., Marchal K. Meta analysis of gene expression data within and across species. Curr. Genomics 2008, 9:525-534.
-
(2008)
Curr. Genomics
, vol.9
, pp. 525-534
-
-
Fierro, A.C.1
Vandenbussche, F.2
Engelen, K.3
Van de Peer, Y.4
Marchal, K.5
-
24
-
-
0030479071
-
A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins
-
Kim S.S., Chen Y.M., O'Leary E., Witzgall R., Vidal M., Bonventre J.V. A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins. Proc. Natl. Acad. Sci. USA 1996, 93:15299-15304.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15299-15304
-
-
Kim, S.S.1
Chen, Y.M.2
O'Leary, E.3
Witzgall, R.4
Vidal, M.5
Bonventre, J.V.6
-
25
-
-
0029858585
-
KAP-1, a novel corepressor for the highly conserved KRAB repression domain
-
Friedman J.R., Fredericks W.J., Jensen D.E., Speicher D.W., Huang X.P., Neilson E.G., Rauscher F.J. KAP-1, a novel corepressor for the highly conserved KRAB repression domain. Genes Dev. 1996, 10:2067-2078.
-
(1996)
Genes Dev.
, vol.10
, pp. 2067-2078
-
-
Friedman, J.R.1
Fredericks, W.J.2
Jensen, D.E.3
Speicher, D.W.4
Huang, X.P.5
Neilson, E.G.6
Rauscher, F.J.7
-
26
-
-
0033522644
-
Two novel Kruppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 TIF1 beta/KRIP-1
-
Agata Y., Matsuda E., Shimizu A. Two novel Kruppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 TIF1 beta/KRIP-1. J. Biol. Chem. 1999, 274:16412-16422.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16412-16422
-
-
Agata, Y.1
Matsuda, E.2
Shimizu, A.3
-
27
-
-
0037089626
-
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
-
Schultz D.C., Ayyanathan K., Negorev D., Maul G.G., Rauscher F.J. SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev. 2002, 16:919-932.
-
(2002)
Genes Dev.
, vol.16
, pp. 919-932
-
-
Schultz, D.C.1
Ayyanathan, K.2
Negorev, D.3
Maul, G.G.4
Rauscher, F.J.5
-
28
-
-
0035118229
-
Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD
-
Schultz D.C., Friedman J.R., Rauscher F.J. Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD. Genes Dev. 2001, 15:428-443.
-
(2001)
Genes Dev.
, vol.15
, pp. 428-443
-
-
Schultz, D.C.1
Friedman, J.R.2
Rauscher, F.J.3
-
29
-
-
0034704078
-
A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1
-
Underhill C., Qutob M.S., Yee S.P., Torchia J. A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1. J. Biol. Chem. 2000, 275:40463-40470.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40463-40470
-
-
Underhill, C.1
Qutob, M.S.2
Yee, S.P.3
Torchia, J.4
-
30
-
-
2642582334
-
Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene
-
Niculescu M.D., Yamamuro Y., Zeisel S.H. Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene. J. Neurochem. 2004, 89:1252-1259.
-
(2004)
J. Neurochem.
, vol.89
, pp. 1252-1259
-
-
Niculescu, M.D.1
Yamamuro, Y.2
Zeisel, S.H.3
-
31
-
-
20444469639
-
Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP). Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2
-
Chinami M., Yano Y., Yang X., Salahuddin S., Moriyama K., Shiroishi M., Turner H., Shirakawa T., Adra C.N. Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP). Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2. J. Biol. Chem 2005, 280:17235-17242.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 17235-17242
-
-
Chinami, M.1
Yano, Y.2
Yang, X.3
Salahuddin, S.4
Moriyama, K.5
Shiroishi, M.6
Turner, H.7
Shirakawa, T.8
Adra, C.N.9
-
32
-
-
33846457387
-
Aberrant splicing of cyclin-dependent kinase-associated protein phosphatase KAP increases proliferation and migration in glioblastoma
-
Yu Y., Jiang X., Schoch B.S., Carroll R.S., Black P.M., Johnson M.D. Aberrant splicing of cyclin-dependent kinase-associated protein phosphatase KAP increases proliferation and migration in glioblastoma. Cancer Res. 2007, 67:130-138.
-
(2007)
Cancer Res.
, vol.67
, pp. 130-138
-
-
Yu, Y.1
Jiang, X.2
Schoch, B.S.3
Carroll, R.S.4
Black, P.M.5
Johnson, M.D.6
-
33
-
-
0028899480
-
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
-
Chen J., Jackson P.K., Kirschner M.W., Dutta A. Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature 1995, 374:386-388.
-
(1995)
Nature
, vol.374
, pp. 386-388
-
-
Chen, J.1
Jackson, P.K.2
Kirschner, M.W.3
Dutta, A.4
-
34
-
-
0034635914
-
Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases
-
Chang B.D., Watanabe K., Broude E.V., Fang J., Poole J.C., Kalinichenko T.V., Roninson I.B. Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases. Proc. Natl. Acad. Sci. USA 2000, 97:4291-4296.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4291-4296
-
-
Chang, B.D.1
Watanabe, K.2
Broude, E.V.3
Fang, J.4
Poole, J.C.5
Kalinichenko, T.V.6
Roninson, I.B.7
-
35
-
-
0033541491
-
Hepatocellular carcinoma
-
Schafer D.F., Sorrell M.F. Hepatocellular carcinoma. Lancet 1999, 353:1253-1257.
-
(1999)
Lancet
, vol.353
, pp. 1253-1257
-
-
Schafer, D.F.1
Sorrell, M.F.2
-
36
-
-
0025789973
-
Factors linked to early recurrence of small hepatocellular carcinoma after hepatectomy: univariate and multivariate analyses
-
Shirabe K., Kanematsu T., Matsumata T., Adachi E., Akazawa K., Sugimachi K. Factors linked to early recurrence of small hepatocellular carcinoma after hepatectomy: univariate and multivariate analyses. Hepatology 1991, 14:802-805.
-
(1991)
Hepatology
, vol.14
, pp. 802-805
-
-
Shirabe, K.1
Kanematsu, T.2
Matsumata, T.3
Adachi, E.4
Akazawa, K.5
Sugimachi, K.6
-
38
-
-
0030746636
-
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
-
Ambrosini G., Adida C., Altieri D.C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat. Med. 1997, 3:917-921.
-
(1997)
Nat. Med.
, vol.3
, pp. 917-921
-
-
Ambrosini, G.1
Adida, C.2
Altieri, D.C.3
-
39
-
-
0032506524
-
Control of apoptosis and mitotic spindle checkpoint by survivin
-
Li F., Ambrosini G., Chu E.Y., Plescia J., Tognin S., Marchisio P.C., Altieri D.C. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 1998, 396:580-584.
-
(1998)
Nature
, vol.396
, pp. 580-584
-
-
Li, F.1
Ambrosini, G.2
Chu, E.Y.3
Plescia, J.4
Tognin, S.5
Marchisio, P.C.6
Altieri, D.C.7
-
40
-
-
0036570207
-
Regulation of microtubule stability and mitotic progression by survivin
-
Giodini A., Kallio M.J., Wall N.R., Gorbsky G.J., Tognin S., Marchisio P.C., Symons M., Altieri D.C. Regulation of microtubule stability and mitotic progression by survivin. Cancer Res. 2002, 62:2462-2467.
-
(2002)
Cancer Res.
, vol.62
, pp. 2462-2467
-
-
Giodini, A.1
Kallio, M.J.2
Wall, N.R.3
Gorbsky, G.J.4
Tognin, S.5
Marchisio, P.C.6
Symons, M.7
Altieri, D.C.8
-
41
-
-
54249134409
-
Nuclear survivin abrogates multiple cell cycle checkpoints and enhances viral oncolysis
-
Connell C.M., Wheatley S.P., McNeish I.A. Nuclear survivin abrogates multiple cell cycle checkpoints and enhances viral oncolysis. Cancer Res. 2008, 68:7923-7931.
-
(2008)
Cancer Res.
, vol.68
, pp. 7923-7931
-
-
Connell, C.M.1
Wheatley, S.P.2
McNeish, I.A.3
|