Glioma derived isocitrate dehydrogenase-2 mutations induced up-regulation of HIF-1α and β-catenin signaling: Possible impact on glioma cell metastasis and chemo-resistance

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 5, 2012, Pages 770-775

  Fu, Yuejun ^a   Zheng, Shuhua ^a   Zheng, Yali ^a   Huang, Rui ^a   An, Na ^a   Liang, Aihua ^a   Hu, Changchen ^b,c  

^a SHANXI UNIVERSITY   (China)

^b SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Catenin; Glioma; HIF 1 ; Isocitrate dehydrogenase; N cadherin

Indexed keywords

BETA ACTIN; BETA CATENIN; CYCLOOXYGENASE 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE ISOENZYME; NERVE CELL ADHESION MOLECULE; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CANCER GROWTH; CANCER INVASION; CANCER RESISTANCE; CARCINOGENESIS; CELL NUCLEUS; CONTROLLED STUDY; GENE; GENE MUTATION; GLIOBLASTOMA; GLIOMA CELL; HETEROZYGOSITY; IDH1 GENE; IDH2 GENE; INCIDENCE; METASTASIS; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ARGININE; BETA CATENIN; BRAIN NEOPLASMS; CELL LINE, TUMOR; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISOCITRATE DEHYDROGENASE; ISOENZYMES; MUTATION; NEOPLASM INVASIVENESS; RATS; SIGNAL TRANSDUCTION; TRANSFECTION; UP-REGULATION;

EID: 84862805460     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.01.017     Document Type: Article

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