Anti-inflammatory recombinant TSG-6 stabilizes the progression of focal retinal degeneration in a murine model

Journal of Neuroinflammation

Volumn 9, Issue , 2012, Pages

  Tuo, Jingsheng ^a   Cao, Xiaoguang ^a   Shen, Defen ^a   Wang, Yujuan ^a   Zhang, Jun ^a   Oh, Joo Y ^b   Prockop, Darwin J ^b   Chan, Chi Chao ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

Author keywords

Age related macular degeneration; Animal model; IL 17A; TNF ; Treatment; TSG 6

Indexed keywords

ANTIINFLAMMATORY AGENT; INTERLEUKIN 17; LIPOFUSCIN; MESSENGER RNA; RECOMBINANT TSG 6; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CCL2 PROTEIN, MOUSE; CELL ADHESION MOLECULE; CHEMOKINE RECEPTOR; CX3CR1 PROTEIN, MOUSE; MONOCYTE CHEMOTACTIC PROTEIN 1; TNFAIP6 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; IL 17A GENE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OPHTHALMOSCOPY; REAL TIME POLYMERASE CHAIN REACTION; RETINA INJURY; RETINA MACULA AGE RELATED DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TNF ALPHA GENE; ANIMAL; C57BL MOUSE; DISEASE COURSE; DISEASE MODEL; GENE EXPRESSION; GENETICS; IMMUNOELECTRON MICROSCOPY; INTRAVITREAL DRUG ADMINISTRATION; METABOLISM; MOUSE MUTANT; OPHTHALMOSCOPE; PATHOLOGY; RETINA; RETINA DEGENERATION; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL ADHESION MOLECULES; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE EXPRESSION; GENE EXPRESSION REGULATION; INTERLEUKIN-17; INTRAVITREAL INJECTIONS; LIPOFUSCIN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, IMMUNOELECTRON; OPHTHALMOSCOPES; RECEPTORS, CHEMOKINE; RETINA; RETINAL DEGENERATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84862804838     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-9-59     Document Type: Article

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