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Volumn 424, Issue , 2012, Pages 130-142

Haemocytic leukemia in Prince Edward Island (PEI) soft shell clam (Mya arenaria): Spatial distribution in agriculturally impacted estuaries

Author keywords

Agricultural contaminants; Gene expression; Haemocytic leukemia; Mya arenaria; P53; Prince Edward Island

Indexed keywords

AGRICULTURAL ACTIVITIES; BENTHIC ORGANISMS; CLOSE PROXIMITY; ENDOSULFANS; FILTER FEEDERS; HAEMOCYTIC LEUKEMIA; HIGH INTENSITY; IMMUNOCYTOCHEMISTRY; MYA ARENARIA; P53; POTATO FARMING; PRINCE EDWARD ISLAND; SOFT SHELL CLAMS; SURFACE SEDIMENTS; TUMOUR SUPPRESSOR; WATERSOLUBLE;

EID: 84862799746     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2012.02.029     Document Type: Article
Times cited : (20)

References (65)
  • 1
    • 71049176326 scopus 로고    scopus 로고
    • Department of Fisheries, Aquaculture, and Environment, Charlottetown, Prince Edward Island, Anonymous
    • Anonymous State of the Environment 2003, 61. Department of Fisheries, Aquaculture, and Environment, Charlottetown, Prince Edward Island.
    • (2003) State of the Environment , pp. 61
  • 2
    • 84862829913 scopus 로고    scopus 로고
    • Fisheries and Oceans Canada, Available from, [accessed April 20, 2011], Anonymous
    • Anonymous Aquaculture in Eastern Canada 2005, Fisheries and Oceans Canada, Available from, [accessed April 20, 2011]. http://www.dfo-mpo.gc.ca/aquaculture/multimedia/ppt_200511-eng.htm.
    • (2005) Aquaculture in Eastern Canada
  • 3
    • 84862781706 scopus 로고    scopus 로고
    • Pest Management Regulatory Agency, Ottawa, Anonymous
    • Anonymous Re-evaluation note REV2010-16: Endosulfan 2010, 9. Pest Management Regulatory Agency, Ottawa.
    • (2010) Re-evaluation note REV2010-16: Endosulfan , pp. 9
  • 5
    • 84862797443 scopus 로고    scopus 로고
    • Department of Environment, Energy, and Forestry PEI, Available from, [accessed November 1, 2011], Anonymous
    • Anonymous Surface Water Quality of PEI 2011, Department of Environment, Energy, and Forestry PEI, Available from, [accessed November 1, 2011]. http://www.gov.pe.ca/envengfor/index.php3?number=1012573&lang=E.
    • (2011) Surface Water Quality of PEI
  • 7
    • 33644559683 scopus 로고    scopus 로고
    • A multiparametric approach for monitoring immunotoxic responses in mussels from contaminated sites in Western Mediterranean
    • Auffret M., Rousseau S., Boutet I., Tanguy A., Baron J., Moraga D., et al. A multiparametric approach for monitoring immunotoxic responses in mussels from contaminated sites in Western Mediterranean. Ecotoxicol Environ Saf 2006, 63:393-405.
    • (2006) Ecotoxicol Environ Saf , vol.63 , pp. 393-405
    • Auffret, M.1    Rousseau, S.2    Boutet, I.3    Tanguy, A.4    Baron, J.5    Moraga, D.6
  • 8
    • 0001407037 scopus 로고
    • The ecological, chemical and histopathological evaluation of an oil spill site: Part III. Histopathological Studies
    • Barry M., Yevich P.P. The ecological, chemical and histopathological evaluation of an oil spill site: Part III. Histopathological Studies. Mar Pollut Bull 1975, 6:171-173.
    • (1975) Mar Pollut Bull , vol.6 , pp. 171-173
    • Barry, M.1    Yevich, P.P.2
  • 10
    • 38849126304 scopus 로고    scopus 로고
    • Genotoxic stress-induced expression of p53 and apoptosis in leukemic clam hemocytes with cytoplasmically sequestered p53
    • Bottger S., Jerszyk E., Low B., Walker C. Genotoxic stress-induced expression of p53 and apoptosis in leukemic clam hemocytes with cytoplasmically sequestered p53. Cancer Res 2008, 68:777-782.
    • (2008) Cancer Res , vol.68 , pp. 777-782
    • Bottger, S.1    Jerszyk, E.2    Low, B.3    Walker, C.4
  • 12
    • 0017657886 scopus 로고
    • Prevalence of neoplasia in 10 New England populations of the soft-shell clam (Mya arenaria)
    • Brown R.S., Wolke R.E., Saila S.B., Brown C.W. Prevalence of neoplasia in 10 New England populations of the soft-shell clam (Mya arenaria). Ann N Y Acad Sci 1978, 298:522-534.
    • (1978) Ann N Y Acad Sci , vol.298 , pp. 522-534
    • Brown, R.S.1    Wolke, R.E.2    Saila, S.B.3    Brown, C.W.4
  • 13
    • 0035980623 scopus 로고    scopus 로고
    • An aryl hydrocarbon receptor (AHR) homologue from the soft-shell clam, Mya arenaria: evidence that invertebrate AHR homologues lack 2,3,7,8-tetrachlorodibenzo-p-dioxin and β-naphthoflavone binding
    • Butler R.A., Kelley M.L., Powell W.H., Hahn M.E., Van Beneden R.J. An aryl hydrocarbon receptor (AHR) homologue from the soft-shell clam, Mya arenaria: evidence that invertebrate AHR homologues lack 2,3,7,8-tetrachlorodibenzo-p-dioxin and β-naphthoflavone binding. Gene 2001, 278:223-234.
    • (2001) Gene , vol.278 , pp. 223-234
    • Butler, R.A.1    Kelley, M.L.2    Powell, W.H.3    Hahn, M.E.4    Van Beneden, R.J.5
  • 14
    • 7944236747 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor (AhR)-independent effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on softshell clam (Mya arenaria) reproductive tissue
    • Butler R.A., Kelley M.L., Olberding K.E., Gardner G.R., Van Beneden R.J. Aryl hydrocarbon receptor (AhR)-independent effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on softshell clam (Mya arenaria) reproductive tissue. Comp Biochem Physiol C Toxicol Pharmacol 2004, 138:375-381.
    • (2004) Comp Biochem Physiol C Toxicol Pharmacol , vol.138 , pp. 375-381
    • Butler, R.A.1    Kelley, M.L.2    Olberding, K.E.3    Gardner, G.R.4    Van Beneden, R.J.5
  • 16
    • 0001692340 scopus 로고
    • Academic Press, London, N.A. Ratcliffe, A.F. Rowley (Eds.)
    • Cheng T.C.Bivalves Invertebrate Blood Cells. 1981, 1:233-300. Academic Press, London. N.A. Ratcliffe, A.F. Rowley (Eds.).
    • (1981) Invertebrate Blood Cells. , vol.1 , pp. 233-300
    • Cheng, T.C.B.1
  • 17
    • 0034311713 scopus 로고    scopus 로고
    • The haemocytes of the clam Tapes philippinarum: a morpho-functional characterisation
    • Cima F., Matozzo V., Marin M.G., Ballarin L. The haemocytes of the clam Tapes philippinarum: a morpho-functional characterisation. Fish Shellfish Immunol 2002, 10:677-693.
    • (2002) Fish Shellfish Immunol , vol.10 , pp. 677-693
    • Cima, F.1    Matozzo, V.2    Marin, M.G.3    Ballarin, L.4
  • 19
    • 78650069174 scopus 로고    scopus 로고
    • Response of the Pacific oyster Crassostrea gigas, Thunberg 1793, to pesticide exposure under experimental conditions
    • Collin H., Meistertzheim A.L., David E., Moraga D., Boutet I. Response of the Pacific oyster Crassostrea gigas, Thunberg 1793, to pesticide exposure under experimental conditions. J Exp Biol 2010, 213:4010-4017.
    • (2010) J Exp Biol , vol.213 , pp. 4010-4017
    • Collin, H.1    Meistertzheim, A.L.2    David, E.3    Moraga, D.4    Boutet, I.5
  • 20
    • 0003194738 scopus 로고
    • Accuracy of blood cytological screening techniques for the diagnosis of a possible hematopoietic neoplasm in the bivalve mollusc, Mya arenaria
    • Cooper E.L., Brown R., Chang P. Accuracy of blood cytological screening techniques for the diagnosis of a possible hematopoietic neoplasm in the bivalve mollusc, Mya arenaria. J Invertebr Pathol 1982, 39:281-289.
    • (1982) J Invertebr Pathol , vol.39 , pp. 281-289
    • Cooper, E.L.1    Brown, R.2    Chang, P.3
  • 21
    • 0242361576 scopus 로고    scopus 로고
    • P63/73 homologues in surf clam: novel signaling motifs and implications for control of expression
    • Cox R.L., Stephens R.E., Reinisch C.L. p63/73 homologues in surf clam: novel signaling motifs and implications for control of expression. Gene 2003, 320:49-58.
    • (2003) Gene , vol.320 , pp. 49-58
    • Cox, R.L.1    Stephens, R.E.2    Reinisch, C.L.3
  • 22
    • 79952050286 scopus 로고    scopus 로고
    • Nitrogen loadings to two small estuaries, Prince Edward Island, Canada: a 2-year investigation of precipitation, surface water and groundwater contributions
    • Danielescu S., MacQuarrie K.T.B. Nitrogen loadings to two small estuaries, Prince Edward Island, Canada: a 2-year investigation of precipitation, surface water and groundwater contributions. Hydrol Processes 2011, 25:945-957.
    • (2011) Hydrol Processes , vol.25 , pp. 945-957
    • Danielescu, S.1    MacQuarrie, K.T.B.2
  • 23
    • 70349232441 scopus 로고    scopus 로고
    • The integration of thermal infrared imaging, discharge measurements and numerical simulation to quantify the relative contributions of freshwater inflows to small estuaries in Atlantic Canada
    • Danielescu S., MacQuarrie K.T.B., Faux R.N. The integration of thermal infrared imaging, discharge measurements and numerical simulation to quantify the relative contributions of freshwater inflows to small estuaries in Atlantic Canada. Hydrol Processes 2009, 23:2847-2859.
    • (2009) Hydrol Processes , vol.23 , pp. 2847-2859
    • Danielescu, S.1    MacQuarrie, K.T.B.2    Faux, R.N.3
  • 24
    • 49949108336 scopus 로고    scopus 로고
    • Immunophenotyping of Mya arenaria neoplastic hemocytes using propidium iodide and a specific monoclonal antibody by flow cytometry
    • Delaporte M., McKenna P., Siah A., Berthe F.C. Immunophenotyping of Mya arenaria neoplastic hemocytes using propidium iodide and a specific monoclonal antibody by flow cytometry. J Invertebr Pathol 2008, 99:120-122.
    • (2008) J Invertebr Pathol , vol.99 , pp. 120-122
    • Delaporte, M.1    McKenna, P.2    Siah, A.3    Berthe, F.C.4
  • 25
    • 0030041211 scopus 로고    scopus 로고
    • Detection of micronuclei in hemocytes of Mya arenaria: association with leukemia and induction with an alkylating agent
    • Dopp E., Barker C.M., Schiffmann D., Reinisch C.L. Detection of micronuclei in hemocytes of Mya arenaria: association with leukemia and induction with an alkylating agent. Aquat Toxicol 1996, 34:31-45.
    • (1996) Aquat Toxicol , vol.34 , pp. 31-45
    • Dopp, E.1    Barker, C.M.2    Schiffmann, D.3    Reinisch, C.L.4
  • 27
    • 78651444730 scopus 로고    scopus 로고
    • Evaluation of buffer zone effectiveness in mitigating the risks associated with agricultural runoff in Prince Edward Island
    • Dunn A.M., Julien G., Ernst W.R., Cook A., Doe K.G., Jackman P.M. Evaluation of buffer zone effectiveness in mitigating the risks associated with agricultural runoff in Prince Edward Island. Sci Total Environ 2011, 409:868-882.
    • (2011) Sci Total Environ , vol.409 , pp. 868-882
    • Dunn, A.M.1    Julien, G.2    Ernst, W.R.3    Cook, A.4    Doe, K.G.5    Jackman, P.M.6
  • 28
    • 84857099919 scopus 로고    scopus 로고
    • Investigation of an Escherichia coli environmental benchmark for waterborne pathogens in agricultural watersheds in Canada
    • Edge T.A., El-Shaarawi A., Gannon V., Jokinen C., Kent R., Khan I.U.H., et al. Investigation of an Escherichia coli environmental benchmark for waterborne pathogens in agricultural watersheds in Canada. J Environ Qual 2012, 41:21-30.
    • (2012) J Environ Qual , vol.41 , pp. 21-30
    • Edge, T.A.1    El-Shaarawi, A.2    Gannon, V.3    Jokinen, C.4    Kent, R.5    Khan, I.U.H.6
  • 29
    • 0001141213 scopus 로고
    • Disseminated neoplasia of bivalve molluscs
    • Elston R.A., Moore J.D., Brooks K. Disseminated neoplasia of bivalve molluscs. Rev Aquat Sci 1992, 6:405-466.
    • (1992) Rev Aquat Sci , vol.6 , pp. 405-466
    • Elston, R.A.1    Moore, J.D.2    Brooks, K.3
  • 30
    • 0025910560 scopus 로고
    • Epizootiology and distribution of transmissible sarcoma in Maryland softshell clams, Mya arenaria, 1984-1988
    • Farley C.A., Plutschak D.L., Scott R.F. Epizootiology and distribution of transmissible sarcoma in Maryland softshell clams, Mya arenaria, 1984-1988. Environ Health Perspect 1991, 90:35-41.
    • (1991) Environ Health Perspect , vol.90 , pp. 35-41
    • Farley, C.A.1    Plutschak, D.L.2    Scott, R.F.3
  • 31
    • 0034689586 scopus 로고    scopus 로고
    • Beyond the Mussel Watch-new directions for monitoring marine pollution
    • Goldberg E.D., Bertine K.K. Beyond the Mussel Watch-new directions for monitoring marine pollution. Sci Total Environ 2000, 247:165-174.
    • (2000) Sci Total Environ , vol.247 , pp. 165-174
    • Goldberg, E.D.1    Bertine, K.K.2
  • 32
    • 26444601254 scopus 로고    scopus 로고
    • Changes in salmonid communities associated with pesticide runoff events
    • Gormley K.L., Teather K.L., Guignion D.L. Changes in salmonid communities associated with pesticide runoff events. Ecotoxicology 2005, 14:671-678.
    • (2005) Ecotoxicology , vol.14 , pp. 671-678
    • Gormley, K.L.1    Teather, K.L.2    Guignion, D.L.3
  • 33
    • 33748488877 scopus 로고    scopus 로고
    • Unexpected diversity of aryl hydrocarbon receptors in non-mammalian vertebrates: insights from comparative genomics
    • Hahn M.E., Karchner S.I., Evans B.R., Franks D.G., Merson R.R., Lapseritis J.M. Unexpected diversity of aryl hydrocarbon receptors in non-mammalian vertebrates: insights from comparative genomics. J Exp Zool A Comp Exp Biol 2006, 305:693-706.
    • (2006) J Exp Zool A Comp Exp Biol , vol.305 , pp. 693-706
    • Hahn, M.E.1    Karchner, S.I.2    Evans, B.R.3    Franks, D.G.4    Merson, R.R.5    Lapseritis, J.M.6
  • 34
    • 0000833533 scopus 로고    scopus 로고
    • The inter-relationships of bivalve haemocytes
    • Hine P.M. The inter-relationships of bivalve haemocytes. Fish Shellfish Immunol 1999, 9:367-385.
    • (1999) Fish Shellfish Immunol , vol.9 , pp. 367-385
    • Hine, P.M.1
  • 35
    • 0037247806 scopus 로고    scopus 로고
    • Assessment of seasonal variability of cytochemical responses to contaminant exposure in the blue mussel Mytilus edulis (complex)
    • Kagley A.N., Snider R.G., Krishnakumar P.K., Casillas E. Assessment of seasonal variability of cytochemical responses to contaminant exposure in the blue mussel Mytilus edulis (complex). Arch Environ Contam Toxicol 2003, 44:43-52.
    • (2003) Arch Environ Contam Toxicol , vol.44 , pp. 43-52
    • Kagley, A.N.1    Snider, R.G.2    Krishnakumar, P.K.3    Casillas, E.4
  • 36
    • 0035825576 scopus 로고    scopus 로고
    • Expression of homologues for p53 and p73 in the softshell clam (Mya arenaria), a naturally-occurring model for human cancer
    • Kelley M.L., Winge P., Heaney J.D., Stephens R.E., Farell J.H., Van Beneden R.J., et al. Expression of homologues for p53 and p73 in the softshell clam (Mya arenaria), a naturally-occurring model for human cancer. Oncogene 2001, 20:748-758.
    • (2001) Oncogene , vol.20 , pp. 748-758
    • Kelley, M.L.1    Winge, P.2    Heaney, J.D.3    Stephens, R.E.4    Farell, J.H.5    Van Beneden, R.J.6
  • 37
    • 77953685471 scopus 로고    scopus 로고
    • Impacts of stage-specific acute pesticide exposure on predicted population structure of the soft-shell clam, Mya arenaria
    • Lindsay S., Chasse J., Butler R.A., Morrill W., Van Beneden R.J. Impacts of stage-specific acute pesticide exposure on predicted population structure of the soft-shell clam, Mya arenaria. Aquat Toxicol 2010, 98:265-274.
    • (2010) Aquat Toxicol , vol.98 , pp. 265-274
    • Lindsay, S.1    Chasse, J.2    Butler, R.A.3    Morrill, W.4    Van Beneden, R.J.5
  • 38
    • 0242494051 scopus 로고    scopus 로고
    • Effects of currently used pesticides in the AhR-CALUX assay: comparison between the human TV101L and the rat H4IIE cell line
    • Long M., Laier P., Vinggaard A.M., Andersen H.R., Lynggaard J., Bonefeld-Jørgensen E.C. Effects of currently used pesticides in the AhR-CALUX assay: comparison between the human TV101L and the rat H4IIE cell line. Toxicology 2003, 194:77-93.
    • (2003) Toxicology , vol.194 , pp. 77-93
    • Long, M.1    Laier, P.2    Vinggaard, A.M.3    Andersen, H.R.4    Lynggaard, J.5    Bonefeld-Jørgensen, E.C.6
  • 39
    • 0017882552 scopus 로고
    • Cytology and quantitative cytochemistry of a poliferative atypical hemocytic condition in Mytilus edulis (Bivalvia, mollusca)
    • Lowe D.M., Moore M.N. Cytology and quantitative cytochemistry of a poliferative atypical hemocytic condition in Mytilus edulis (Bivalvia, mollusca). J Natl Cancer Inst 1978, 60:1455-1459.
    • (1978) J Natl Cancer Inst , vol.60 , pp. 1455-1459
    • Lowe, D.M.1    Moore, M.N.2
  • 41
    • 4644340403 scopus 로고    scopus 로고
    • Haemic neoplasia in soft-shell clams (Mya arenaria): recent outbreaks in Atlantic Canada and discovery of a p53 gene homologue associated with the condition
    • McGladdery S., Reinisch C.L., MacCallum G., Stephens R.E., Walker C., Davidson J. Haemic neoplasia in soft-shell clams (Mya arenaria): recent outbreaks in Atlantic Canada and discovery of a p53 gene homologue associated with the condition. Bull Aquacult Assoc Can 2001, 101:19-26.
    • (2001) Bull Aquacult Assoc Can , vol.101 , pp. 19-26
    • McGladdery, S.1    Reinisch, C.L.2    MacCallum, G.3    Stephens, R.E.4    Walker, C.5    Davidson, J.6
  • 42
    • 0024568987 scopus 로고
    • Leukemia cell specific protein of the bivalve mollusc Mya arenaria
    • Miosky D.L., Smolowitz R.M., Reinisch C.L. Leukemia cell specific protein of the bivalve mollusc Mya arenaria. J Invertebr Pathol 1989, 53:32-40.
    • (1989) J Invertebr Pathol , vol.53 , pp. 32-40
    • Miosky, D.L.1    Smolowitz, R.M.2    Reinisch, C.L.3
  • 45
    • 52949116785 scopus 로고    scopus 로고
    • Invertebrate p53-like mRNA isoforms are differentially expressed in mussel haemic neoplasia
    • Muttray A.F., Schulte P.M., Baldwin S.A. Invertebrate p53-like mRNA isoforms are differentially expressed in mussel haemic neoplasia. Mar Environ Res 2008, 66:412-421.
    • (2008) Mar Environ Res , vol.66 , pp. 412-421
    • Muttray, A.F.1    Schulte, P.M.2    Baldwin, S.A.3
  • 46
    • 84862781707 scopus 로고    scopus 로고
    • Screening neoplastic haemocytes of two Mytilus species for changes in gene expression
    • 27th Congress of the new European Society of Comparative Biochemistry and Physiology - Biological effects of climatic changes and pollution: from biomarkers to system biology
    • Muttray A., Dondero F., Vassilenko E., Negri A., Baldwin S., Viarengo A. Screening neoplastic haemocytes of two Mytilus species for changes in gene expression. Comparative Biochemistry and Physiology Part A, Alessandria, Italy 2010, 157:S6.
    • (2010) Comparative Biochemistry and Physiology Part A, Alessandria, Italy , vol.157
    • Muttray, A.1    Dondero, F.2    Vassilenko, E.3    Negri, A.4    Baldwin, S.5    Viarengo, A.6
  • 47
    • 77954865637 scopus 로고    scopus 로고
    • An invertebrate mdm homolog interacts with p53 and is differentially expressed together with p53 and ras in neoplastic Mytilus trossulus haemocytes
    • Muttray A.F., O'Toole T.F., Morrill W., Van Beneden R.J., Baldwin S.A. An invertebrate mdm homolog interacts with p53 and is differentially expressed together with p53 and ras in neoplastic Mytilus trossulus haemocytes. Comp Biochem Physiol B Biochem Mol Biol 2010, 156:298-308.
    • (2010) Comp Biochem Physiol B Biochem Mol Biol , vol.156 , pp. 298-308
    • Muttray, A.F.1    O'Toole, T.F.2    Morrill, W.3    Van Beneden, R.J.4    Baldwin, S.A.5
  • 49
    • 63749127754 scopus 로고    scopus 로고
    • Potential link between exposure to fungicides chlorothalonil and mancozeb and haemic neoplasia development in the soft-shell clam Mya arenaria: a laboratory experiment
    • Pariseau J., Saint-Louis R., Delaporte M., El Khair M.A., McKenna P., Tremblay R. Potential link between exposure to fungicides chlorothalonil and mancozeb and haemic neoplasia development in the soft-shell clam Mya arenaria: a laboratory experiment. Mar Pollut Bull 2009, 58:503-514.
    • (2009) Mar Pollut Bull , vol.58 , pp. 503-514
    • Pariseau, J.1    Saint-Louis, R.2    Delaporte, M.3    El Khair, M.A.4    McKenna, P.5    Tremblay, R.6
  • 50
    • 0000911250 scopus 로고
    • Environmental contaminants influencing immune function in marine bivalve mollusks
    • Pipe R.K., Coles J.A. Environmental contaminants influencing immune function in marine bivalve mollusks. Fish Shellfish Immunol 1995, 5:581-595.
    • (1995) Fish Shellfish Immunol , vol.5 , pp. 581-595
    • Pipe, R.K.1    Coles, J.A.2
  • 51
    • 0028976723 scopus 로고
    • Evidence for environmentally derived immunomodulation in mussels from the Venice Lagoon
    • Pipe R.K., Coles J.A., Thomas M.E., Fossatob V.U., Pulsford A.L. Evidence for environmentally derived immunomodulation in mussels from the Venice Lagoon. Aquat Toxicol 1995, 32:59-73.
    • (1995) Aquat Toxicol , vol.32 , pp. 59-73
    • Pipe, R.K.1    Coles, J.A.2    Thomas, M.E.3    Fossatob, V.U.4    Pulsford, A.L.5
  • 52
    • 0020585453 scopus 로고
    • Unique antigens on neoplastic cells of the soft shell clam Mya arenaria
    • Reinisch C.L., Charles A.M., Troutner J. Unique antigens on neoplastic cells of the soft shell clam Mya arenaria. Dev Comp Immunol 1983, 7:33-39.
    • (1983) Dev Comp Immunol , vol.7 , pp. 33-39
    • Reinisch, C.L.1    Charles, A.M.2    Troutner, J.3
  • 53
    • 0021706024 scopus 로고
    • Epizootic neoplasia in soft shell clams collected from New Bedford Harbor
    • Reinisch C.L., Charles A.M., Stone A.M. Epizootic neoplasia in soft shell clams collected from New Bedford Harbor. Hazard Waste 1984, 1:73-81.
    • (1984) Hazard Waste , vol.1 , pp. 73-81
    • Reinisch, C.L.1    Charles, A.M.2    Stone, A.M.3
  • 54
    • 0024076362 scopus 로고
    • Kidney and hemocytes of Mya arenaria (Bivalvia): normal and pollution-related ultrastructural morphologies
    • Seiler G.R., Morse M.P. Kidney and hemocytes of Mya arenaria (Bivalvia): normal and pollution-related ultrastructural morphologies. J Invertebr Pathol 1988, 52:201-214.
    • (1988) J Invertebr Pathol , vol.52 , pp. 201-214
    • Seiler, G.R.1    Morse, M.P.2
  • 55
    • 44249105857 scopus 로고    scopus 로고
    • Patterns of p53, p73 and mortalin gene expression associated with haemocyte polyploidy in the soft-shell clam, Mya arenaria
    • Siah A., Delaporte M., Pariseau J., McKenna P., Berthe F.C. Patterns of p53, p73 and mortalin gene expression associated with haemocyte polyploidy in the soft-shell clam, Mya arenaria. J Invertebr Pathol 2008, 98:148-152.
    • (2008) J Invertebr Pathol , vol.98 , pp. 148-152
    • Siah, A.1    Delaporte, M.2    Pariseau, J.3    McKenna, P.4    Berthe, F.C.5
  • 56
    • 50249113981 scopus 로고    scopus 로고
    • Selecting a set of housekeeping genes for quantitative real-time PCR in normal and tetraploid haemocytes of soft-shell clams, Mya arenaria
    • Siah A., Dohoo C., McKenna P., Delaporte M., Berthe F.C. Selecting a set of housekeeping genes for quantitative real-time PCR in normal and tetraploid haemocytes of soft-shell clams, Mya arenaria. Fish Shellfish Immunol 2008, 25:202-207.
    • (2008) Fish Shellfish Immunol , vol.25 , pp. 202-207
    • Siah, A.1    Dohoo, C.2    McKenna, P.3    Delaporte, M.4    Berthe, F.C.5
  • 57
    • 29144438083 scopus 로고    scopus 로고
    • Detecting p53 family proteins in haemocytic leukemia cells of Mytilus edulis from Pictou Harbour, Nova Scotia, Canada
    • St.-Jean S.D., Stephens R.E., Courtenay S.C., Reinisch C.L. Detecting p53 family proteins in haemocytic leukemia cells of Mytilus edulis from Pictou Harbour, Nova Scotia, Canada. Can J Fish Aquat Sci 2005, 62:2055-2066.
    • (2005) Can J Fish Aquat Sci , vol.62 , pp. 2055-2066
    • St -Jean, S.D.1    Stephens, R.E.2    Courtenay, S.C.3    Reinisch, C.L.4
  • 58
    • 0034898135 scopus 로고    scopus 로고
    • Multiple protein differences distinguish clam leukemia cells from normal hemocytes: evidence for the involvement of p53 homologues
    • Stephens R.E., Walker C.W., Reinisch C.L. Multiple protein differences distinguish clam leukemia cells from normal hemocytes: evidence for the involvement of p53 homologues. Comp Biochem Physiol C Toxicol Pharmacol 2001, 129:329-338.
    • (2001) Comp Biochem Physiol C Toxicol Pharmacol , vol.129 , pp. 329-338
    • Stephens, R.E.1    Walker, C.W.2    Reinisch, C.L.3
  • 59
    • 0027185183 scopus 로고
    • Implications for the presence of transforming genes in gonadal tumors in two bivalve mollusk species
    • Van Beneden R.J., Gardner G.R., Blake N.J., Blair D.G. Implications for the presence of transforming genes in gonadal tumors in two bivalve mollusk species. Cancer Res 1993, 53:2976-2979.
    • (1993) Cancer Res , vol.53 , pp. 2976-2979
    • Van Beneden, R.J.1    Gardner, G.R.2    Blake, N.J.3    Blair, D.G.4
  • 61
    • 48849103092 scopus 로고    scopus 로고
    • A naturally occurring cancer with molecular connectivity to human diseases
    • Walker C.W., Bottger S.A. A naturally occurring cancer with molecular connectivity to human diseases. Cell Cycle 2008, 7:2286-2289.
    • (2008) Cell Cycle , vol.7 , pp. 2286-2289
    • Walker, C.W.1    Bottger, S.A.2
  • 62
    • 0019620646 scopus 로고
    • A comparison of the incidence of five pathological conditions in soft-shell clams, Mya arenaria, from environments with various pollution histories
    • Walker H.A., Lorda E., Saila S.B. A comparison of the incidence of five pathological conditions in soft-shell clams, Mya arenaria, from environments with various pollution histories. Mar Environ Res 1981, 5:109-123.
    • (1981) Mar Environ Res , vol.5 , pp. 109-123
    • Walker, H.A.1    Lorda, E.2    Saila, S.B.3
  • 63
    • 33646496005 scopus 로고    scopus 로고
    • Mortalin-based cytoplasmic sequestration of p53 in a nonmammalian cancer model
    • Walker C., Bottger S., Low B. Mortalin-based cytoplasmic sequestration of p53 in a nonmammalian cancer model. Am J Pathol 2006, 168:1526-1530.
    • (2006) Am J Pathol , vol.168 , pp. 1526-1530
    • Walker, C.1    Bottger, S.2    Low, B.3
  • 64
    • 60849098729 scopus 로고    scopus 로고
    • Mass culture and characterization of tumor cells from a naturally occurring invertebrate cancer model: applications for human and animal disease and environmental health
    • Walker C., Bottger S.A., Mulkern J., Jerszyk E., Litvaitis M., Lesser M. Mass culture and characterization of tumor cells from a naturally occurring invertebrate cancer model: applications for human and animal disease and environmental health. Biol Bull 2009, 216:23-39.
    • (2009) Biol Bull , vol.216 , pp. 23-39
    • Walker, C.1    Bottger, S.A.2    Mulkern, J.3    Jerszyk, E.4    Litvaitis, M.5    Lesser, M.6
  • 65
    • 0018279119 scopus 로고
    • Neoplasia in soft-shell clams (Mya arenaria) collected from oil-impacted sites
    • Yevich P.P., Barszcz C.A. Neoplasia in soft-shell clams (Mya arenaria) collected from oil-impacted sites. Ann N Y Acad Sci 1978, 298:409-426.
    • (1978) Ann N Y Acad Sci , vol.298 , pp. 409-426
    • Yevich, P.P.1    Barszcz, C.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.