Patterns of p53, p73 and mortalin gene expression associated with haemocyte polyploidy in the soft-shell clam, Mya arenaria

Journal of Invertebrate Pathology

Volumn 98, Issue 2, 2008, Pages 148-152

  Siah, A ^a   Delaporte, M ^a,d   Pariseau, J ^a,b   McKenna, P ^a   Berthe, F C J ^a,c  

^a UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

^b INSTITUT DES SCIENCES DE LA MER DE RIMOUSKI   (Canada)

^c EUROPEAN FOOD SAFETY AUTHORITY   (Italy)

^d UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Haemocytes; Mortalin; Mya arenaria; p53; p73; Tetraploidy

Indexed keywords

DNA BINDING PROTEIN; HEAT SHOCK PROTEIN 70; MORTALIN; NUCLEAR PROTEIN; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIOSYNTHESIS; BLOOD CELL; BLOOD DISEASE; CELL TRANSFORMATION; FLOW CYTOMETRY; GENE EXPRESSION; GENETICS; MYA; PHYSIOLOGY; POLYPLOIDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; DNA-BINDING PROTEINS; FLOW CYTOMETRY; GENE EXPRESSION; GENES, P53; HEMATOLOGIC NEOPLASMS; HEMOCYTES; HSP70 HEAT-SHOCK PROTEINS; MYA; NUCLEAR PROTEINS; POLYPLOIDY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEINS;

BIVALVIA; MYA; MYA ARENARIA;

EID: 44249105857     PISSN: 00222011     EISSN: 10960805     Source Type: Journal    
DOI: 10.1016/j.jip.2008.03.002     Document Type: Article

References (31)

1. Allam B., Ashton-Alcox K.A., and Ford S.E. Flow cytometric comparison of haemocytes from three species of bivalve mollusks. Fish Shellfish Immunol. 13 (2002) 141-158
2. Appeldoorn, R., Brown, C.W., Brown, R.S., Chang, P.W., Cooper, K., Lorda, E., Saila, S.B., Walker, H., Wolke, R.E., 1984. Field and laboratory studies to define the occurrence of neoplasia in the soft shell clam, Mya arenaria. API Publ. No. 4345, American Petroleum Institute, Washington, DC.
3. Ashton-Alcox K.A., and Ford S.E. Variability in molluscan haemocytes: a flow cytometry study. Tissue Cell 30 (1998) 195-204
4. Barber B.J. Neoplastic diseases of commercially important marine bivalves. Aquat. Living Resources 17 (2004) 449-466
5. Barker C.M., Calvert R.J., Walker C.W., and Reinisch C.L. Detection of mutant p53 in clam leukemia cells. Exp. Cell Res. 232 (1997) 240-245
6. Beckmann N., Morse M.P., and Moore C.M. Comparative study of phagocytosis in normal and diseased hemocytes of the bivalve mollusc Mya arenaria. J. Invertebr. Pathol. 59 (1992) 124-132
7. Bode A.M., and Dong Z. Post-translational modification of p53 in tumorigenesis. Nat. Rev. Cancer 4 (2004) 793-805
8. Brousseau D.J., and Baglivo J.A. Disease progression and mortality in neoplastic Mya arenaria in the field. Mar. Biol. 110 (1991) 249-252
9. Da Silva P.M., Soudant P., Carballal M.J., Lambert C., and Villalba A. Flow cytometric DNA content analysis of neoplastic cells in haemolymph of the cockle Cerastoderma edule. Dis. Aquat. Org. 67 (2005) 133-139
10. Delaporte M., Synard S., Pariseau J., McKenna P., Tremblay R., Davidson J., and Berthe F.C.J. Assessment of haemic neoplasia in different soft shell clam Mya arenaria populations from eastern Canada by flow cytometry. J. Invertebr. Pathol. 98 (2008) 190-197
11. Elston R.A., Drum A.S., and Allen S.K. Progressive development of circulating polyploid cells in Mytilus with haemic neoplasia. Dis. Aquat. Org. 8 (1990) 51-59
12. Harms K., Nozell S., and Chen X. The common and distinct target genes of the p53 family transcription factors. Cell Mol. Life Sci. 61 (2004) 822-842
13. Hellemans J., Mortier M., De Paepe A., Speleman F., and Vandesompele J. qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biol. 8 (2007) R19
14. Hofseth L.J., Hussain S.P., and Harris C.C. p53: 25 years after its discovery. Trends Pharmacol. Sci. 25 (2004) 177-181
15. House M.L., Kim C.H., and Reno P.W. Soft shell clams Mya arenaria with disseminated neoplasia demonstrate reverse transcriptase activity. Dis. Aquat. Org. 34 (1998) 187-192
16. Kelley M.L., Winge P., Heaney J.D., Stephens R.E., Farell J.H., Van Beneden R.J., Reinisch C.L., Lesser M.P., and Walker C.W. Expression of homologues for p53 and p73 in the softshell clam (Mya arenaria), a naturally-occurring model for human cancer. Oncogene 20 (2001) 748-758
17. Lane D.P. Cancer: p53, guardian of the genome. Nature 358 (1992) 15-16
18. McGladdery S.E., Reinisch C.L., MacCallum G.S., Stephens R.E., Walker C.L., and Davidson J.T. Haemic neoplasia in soft-shell clams (Mya arenaria): recent outbreaks in Atlantic Canada and discovery of a p53 gene homologue associated with the condition. Can. Bull. Aquat. Assoc. 101 (2001) 19-26
19. Moore J.D., Elston R.A., Drum A.S., and Wilkinson M.T. Alternate pathogenesis of systemic neoplasia in the bivalve mollusc Mytilus. J. Invertebr. Pathol. 58 (1991) 231-243
20. Moore C.A., Beckmann N., and Morse M.P. Cytoskeletal structure of diseased and normal hemocytes of Mya arenaria. J. Invertebr. Pathol. 38 (1992) 141-147
21. Oprandy J.J. 5-Bromodeoxyuridine induction of hematopoietic neoplasia and retrovirus activation in the soft-shell clam, Mya arenaria. J. Invertebr. Pathol. 42 (1983) 196-206
22. Reno P.W., House M., and Illingworth A. Flow cytometry and chromosome analysis of Softshell clams, Mya arenaria, with disseminated neoplasia. J. Invertebr. Pathol. 64 (1994) 163-172
23. Rieder C.L., and Maiato H. Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint. Dev. Cell 7 (2004) 637-651
24. Shi Q., and King R.W. Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines. Nature 437 (2005) 1038-1042
25. Stukenberg P.T. Triggering p53 after cytokinesis failure. J. Cell Biol. 165 (2004) 607-608
26. Stephens R.E., Walker C.W., and Reinisch C.L. Multiple protein differences distinguish clam leukemia cells from normal hemocytes: evidence for the involvement of p53 homologues. Comp. Biochem. Physiol. C 129 (2001) 329-338
27. Toledo F., and Wahl G.M. Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nat. Rev. Cancer 6 (2006) 909-923
28. Vousden K.H., and Lu X. Live or let die: the cell's response to p53. Nat. Rev. Cancer 2 (2002) 594-604
29. Wadhwa R., Taira K., and Kaul S.C. Mortalin: a potential candidate for biotechnology and biomedicine. Histol. Histopathol. 17 (2002) 1173-1177
30. Wadhwa R., Takano S., Kaur K., Deocaris C.C., Pereira-Smith O.M., Reddel R.R., and Kaul S.C. Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis. Int. J. Cancer 118 (2006) 2973-2980
31. Walker C.W., Bottger S., and Low B. Mortalin-based cytoplasmic sequestration of p53 in a non mammalian cancer model. Am. J. Pathol. 168 (2006) 1526-1530