Verapamil does not modify catalytic activity of CYP450 in rainbow trout after long-term exposure

Ecotoxicology and Environmental Safety

Volumn 79, Issue , 2012, Pages 148-152

  Burkina, V ^a   Zamaratskaia, G ^b   Randak, T ^a   Li, Z H ^a   Fedorova, G ^a   Pickova, J ^b   Zlabek, V ^a  

^a UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Biomarker; Cytochrome P450; Hepatic microsomes; Rainbow trout; Verapamil

Indexed keywords

4 NITROPHENOL; 4 NITROPHENOL HYDROXYLASE; 7 BENZYLOXY 4 TRIFLUOROMETHYLCOUMARIN O DEBENZYLASE; COUMARIN; COUMARIN HYDROXYLASE; CYTOCHROME P450; ETHOXYRESORUFIN; ETHOXYRESORUFIN DEETHYLASE; METHOXYRESORUFIN; METHOXYRESORUFIN DEALKYLASE; OXYGENASE; PENTOXYRESORUFIN; PENTOXYRESORUFIN DEALKYLASE; PHENOXAZINE DERIVATIVE; TOLBUTAMIDE; TOLBUTAMIDE HYDROXYLASE; UNCLASSIFIED DRUG; UNCLASSIFIED ENZYME; VERAPAMIL;

BIOACCUMULATION; BIOMARKER; BIOMONITORING; CATALYSIS; DRUG; ENZYME ACTIVITY; FISH; METABOLISM; POLLUTION EXPOSURE; SUBLETHAL EFFECT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DEALKYLATION; DEBENZYLATION; ENZYME ACTIVITY; HYDROXYLATION; IN VIVO STUDY; JUVENILE ANIMAL; LIVER MICROSOME; LONG TERM EXPOSURE; NONHUMAN; RAINBOW TROUT; WATER CONTAMINATION;

ANIMALS; BIOLOGICAL MARKERS; CALCIUM CHANNEL BLOCKERS; COUMARINS; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; LIVER; MICROSOMES, LIVER; NITROPHENOLS; ONCORHYNCHUS MYKISS; OXAZINES; VERAPAMIL; WATER POLLUTANTS, CHEMICAL;

ONCORHYNCHUS MYKISS;

EID: 84862799574     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2011.12.012     Document Type: Article

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