-
1
-
-
33646406554
-
Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice
-
Yang H, Chen D, Cui QC, Yuan X, Dou QP. Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice. Cancer Res 2006; 66:4758-4765.
-
(2006)
Cancer Res
, vol.66
, pp. 4758-4765
-
-
Yang, H.1
Chen, D.2
Cui, Q.C.3
Yuan, X.4
Dou, Q.P.5
-
2
-
-
36749077060
-
Preclinical studies of celastrol and acetyl isogambogic acid in melanoma
-
DOI 10.1158/1078-0432.CCR-07-1536
-
Abbas S, Bhoumik A, Dahl R, Vasile S, Krajewski S, Cosford ND, et al. Preclinical studies of celastrol and acetyl isogambogic acid in melanoma. Clin Cancer Res 2007; 13:6769-6778. (Pubitemid 350206815)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.22
, pp. 6769-6778
-
-
Abbas, S.1
Bhoumik, A.2
Dahl, R.3
Vasile, S.4
Krajewski, S.5
Cosford, N.D.P.6
Ronai, Z.A.7
-
3
-
-
78549293218
-
Celastrol inhibits the growth of estrogen positive human breast cancer cells through modulation of estrogen receptor alpha
-
Jang SY, Jang SW, Ko J. Celastrol inhibits the growth of estrogen positive human breast cancer cells through modulation of estrogen receptor alpha. Cancer Lett 2011; 300:57-65.
-
(2011)
Cancer Lett
, vol.300
, pp. 57-65
-
-
Jang, S.Y.1
Jang, S.W.2
Ko, J.3
-
4
-
-
38349153572
-
A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells
-
Zhang T, Hamza A, Cao X, Wang B, Yu S, Zhan CG, et al. A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells. Mol Cancer Ther 2008; 7:162-170.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 162-170
-
-
Zhang, T.1
Hamza, A.2
Cao, X.3
Wang, B.4
Yu, S.5
Zhan, C.G.6
-
5
-
-
79957961355
-
Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria-and Fas/FasL-mediated pathways
-
Mou H, Zheng Y, Zhao P, Bao H, Fang W, Xu N. Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria-and Fas/FasL-mediated pathways. Toxicol In Vitro 2011; 25:1027-1032.
-
(2011)
Toxicol in Vitro
, vol.25
, pp. 1027-1032
-
-
Mou, H.1
Zheng, Y.2
Zhao, P.3
Bao, H.4
Fang, W.5
Xu, N.6
-
6
-
-
42649088411
-
Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression
-
Huang Y, Zhou Y, Fan Y, Zhou D. Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression. Cancer Lett 2008; 264:101-106.
-
(2008)
Cancer Lett
, vol.264
, pp. 101-106
-
-
Huang, Y.1
Zhou, Y.2
Fan, Y.3
Zhou, D.4
-
7
-
-
72149125851
-
Characterization of celastrol to inhibit hsp90 and cdc37 interaction
-
Zhang T, Li Y, Yu Y, Zou P, Jiang Y, Sun D. Characterization of celastrol to inhibit hsp90 and cdc37 interaction. J Biol Chem 2009; 284: 35381-35389.
-
(2009)
J Biol Chem
, vol.284
, pp. 35381-35389
-
-
Zhang, T.1
Li, Y.2
Yu, Y.3
Zou, P.4
Jiang, Y.5
Sun, D.6
-
8
-
-
68849116745
-
Pharmacologic inhibitors of IkappaB kinase suppress growth and migration of mammary carcinosarcoma cells in vitro and prevent osteolytic bone metastasis in vivo
-
Idris AI, Libouban H, Nyangoga H, Landao-Bassonga E, Chappard D, Ralston SH. Pharmacologic inhibitors of IkappaB kinase suppress growth and migration of mammary carcinosarcoma cells in vitro and prevent osteolytic bone metastasis in vivo. Mol Cancer Ther 2009; 8: 2339-2347.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2339-2347
-
-
Idris, A.I.1
Libouban, H.2
Nyangoga, H.3
Landao-Bassonga, E.4
Chappard, D.5
Ralston, S.H.6
-
9
-
-
77954917015
-
Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway
-
Zhu H, Liu XW, Cai TY, Cao J, Tu CX, Lu W, et al. Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway. J Pharmacol Exp Ther 2010; 334:489-499.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 489-499
-
-
Zhu, H.1
Liu, X.W.2
Cai, T.Y.3
Cao, J.4
Tu, C.X.5
Lu, W.6
-
10
-
-
0027495708
-
Liposomes as carriers of cancer chemotherapy. Current status and future prospects
-
Kim S. Liposomes as carriers of cancer chemotherapy. Current status and future prospects. Drugs 1993; 46:618-638.
-
(1993)
Drugs
, vol.46
, pp. 618-638
-
-
Kim, S.1
-
11
-
-
0026352832
-
Sterically stabilized liposomes: Improvements in pharmacokinetics and antitumor therapeutic efficacy
-
Papahadjopoulos D, Allen TM, Gabizon A, Mayhew E, Matthay K, Huang SK, et al. Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy. Proc Natl Acad Sci USA 1991; 88:11460-11464. (Pubitemid 21916061)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.24
, pp. 11460-11464
-
-
Papahadjopoulos, D.1
Allen, T.M.2
Gabizon, A.3
Mayhew, E.4
Matthay, K.5
Huang, S.K.6
Lee, K.-D.7
Woodle, M.C.8
Lasic, D.D.9
Redemann, C.10
Martin, F.J.11
-
12
-
-
21344456131
-
Interaction of clonixin with EPC liposomes used as membrane models
-
DOI 10.1002/jps.20351
-
Ferreira H, Lucio M, Lima JL, Matos C, Reis S. Interaction of clonixin with EPC liposomes used as membrane models. J Pharm Sci 2005; 94:1277-1287. (Pubitemid 40904191)
-
(2005)
Journal of Pharmaceutical Sciences
, vol.94
, Issue.6
, pp. 1277-1287
-
-
Ferreira, H.1
Lucio, M.2
Lima, J.L.F.C.3
Matos, C.4
Reis, S.5
-
13
-
-
34548061783
-
Enhanced antitumor effect of combined triptolide and ionizing radiation
-
DOI 10.1158/1078-0432.CCR-07-0416
-
Wang W, Yang S, Su Y, Xiao Z, Wang C, Li X, et al. Enhanced antitumor effect of combined triptolide and ionizing radiation. Clin Cancer Res 2007; 13:4891-4899. (Pubitemid 47294797)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.16
, pp. 4891-4899
-
-
Wang, W.1
Yang, S.2
Su, Y.3
Xiao, Z.4
Wang, C.5
Li, X.6
Lin, L.7
Fenton, B.M.8
Paoni, S.F.9
Ding, I.10
Keng, P.11
Okunieff, P.12
Zhang, L.13
-
14
-
-
0030806295
-
New nortriterpenoid isolated from anti-rheumatoid arthritic plant, Tripterygium wilfordii, modulates tumor growth and neovascularization
-
DOI 10.1002/(SICI)1097-0215(19970807)72:4<657::AID-IJC18>3.0.CO;2-8
-
Ushiro S, Ono M, Nakayama J, Fujiwara T, Komatsu Y, Sugimachi K, et al. New nortriterpenoid isolated from anti-rheumatoid arthritic plant, Tripterygium wilfordii, modulates tumor growth and neovascularization. Int J Cancer 1997; 72:657-663. (Pubitemid 27356169)
-
(1997)
International Journal of Cancer
, vol.72
, Issue.4
, pp. 657-663
-
-
Ushiro, S.1
Ono, M.2
Nakayama, J.3
Fujiwara, T.4
Komatsu, Y.5
Sugimachi, K.6
Kuwano, M.7
-
15
-
-
78650733125
-
Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB
-
Dai Y, Desano J, Tang W, Meng X, Meng Y, Burstein E, et al. Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB. PLoS One 2010; 5:e14153.
-
(2010)
PLoS One
, vol.5
-
-
Dai, Y.1
Desano, J.2
Tang, W.3
Meng, X.4
Meng, Y.5
Burstein, E.6
-
16
-
-
33750008443
-
Inhibition of NF-kappaB activation through targeting IkappaB kinase by celastrol, a quinone methide triterpenoid
-
DOI 10.1016/j.bcp.2006.08.014, PII S0006295206005041
-
Lee JH, Koo TH, Yoon H, Jung HS, Jin HZ, Lee K, et al. Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid. Biochem Pharmacol 2006; 72:1311-1321. (Pubitemid 44572192)
-
(2006)
Biochemical Pharmacology
, vol.72
, Issue.10
, pp. 1311-1321
-
-
Lee, J.-H.1
Koo, T.H.2
Yoon, H.3
Jung, H.S.4
Jin, H.Z.5
Lee, K.6
Hong, Y.-S.7
Lee, J.J.8
-
17
-
-
77950234271
-
Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway
-
Pang X, Yi Z, Zhang J, Lu B, Sung B, Qu W, et al. Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway. Cancer Res 2010; 70:1951-1959.
-
(2010)
Cancer Res
, vol.70
, pp. 1951-1959
-
-
Pang, X.1
Yi, Z.2
Zhang, J.3
Lu, B.4
Sung, B.5
Qu, W.6
-
18
-
-
77950818403
-
HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way
-
Peng B, Xu L, Cao F, Wei T, Yang C, Uzan G, et al. HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way. Mol Cancer 2010; 9:79.
-
(2010)
Mol Cancer
, vol.9
, pp. 79
-
-
Peng, B.1
Xu, L.2
Cao, F.3
Wei, T.4
Yang, C.5
Uzan, G.6
-
19
-
-
33947598693
-
Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation
-
DOI 10.1182/blood-2006-10-050807
-
Sethi G, Ahn KS, Pandey MK, Aggarwal BB. Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation. Blood 2007; 109:2727-2735. (Pubitemid 46482064)
-
(2007)
Blood
, vol.109
, Issue.7
, pp. 2727-2735
-
-
Sethi, G.1
Kwang, S.A.2
Pandey, M.K.3
Aggarwal, B.B.4
-
21
-
-
0031729149
-
Liposomal drug formulations. Rationale for development and what we can expect for the future
-
Allen TM. Liposomal drug formulations. Rationale for development and what we can expect for the future. Drugs 1998; 56:747-756.
-
(1998)
Drugs
, vol.56
, pp. 747-756
-
-
Allen, T.M.1
-
22
-
-
17644391325
-
Liposomal drug delivery systems - Clinical applications
-
Goyal P, Goyal K, Vijaya Kumar SG, Singh A, Katare OP, Mishra DN. Liposomal drug delivery systems - clinical applications. Acta Pharm 2005; 55:1-25. (Pubitemid 40562616)
-
(2005)
Acta Pharmaceutica
, vol.55
, Issue.1
, pp. 1-25
-
-
Goyal, P.1
Goyal, K.2
Kumar, S.G.V.3
Singh, A.4
Katare, O.P.5
Mishra, D.N.6
-
23
-
-
0036677070
-
Liposomes for intravenous drug targeting: Design and applications
-
Metselaar JM, Mastrobattista E, Storm G. Liposomes for intravenous drug targeting: design and applications. Mini Rev Med Chem 2002; 2: 319-329.
-
(2002)
Mini Rev Med Chem
, vol.2
, pp. 319-329
-
-
Metselaar, J.M.1
Mastrobattista, E.2
Storm, G.3
-
24
-
-
85012373035
-
Diffusion of univalent ions across the lamellae of swollen phospholipids
-
Bangham AD, Standish MM,Watkins JC. Diffusion of univalent ions across the lamellae of swollen phospholipids. J Mol Biol 1965; 13:238-252.
-
(1965)
J Mol Biol
, vol.13
, pp. 238-252
-
-
Bangham, A.D.1
Standish, M.M.2
Watkins, J.C.3
-
25
-
-
0032516078
-
Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment
-
DOI 10.1073/pnas.95.8.4607
-
Hobbs SK, Monsky WL, Yuan F, Roberts WG, Griffith L, Torchilin VP, et al. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci USA 1998; 95:4607-4612. (Pubitemid 28207960)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.8
, pp. 4607-4612
-
-
Hobbs, S.K.1
Monsky, W.L.2
Yuan, F.3
Roberts, W.G.4
Griffith, L.5
Torchilin, V.P.6
Jain, R.K.7
-
26
-
-
0022273738
-
Uptake and intracellular processing of targeted and nontargeted liposomes by rat Kupffer cells in vivo and in vitro
-
Scherphof GL, Dijkstra J, Spanjer HH, Derksen JT, Roerdink FH. Uptake and intracellular processing of targeted and nontargeted liposomes by rat Kupffer cells in vivo and in vitro. Ann N Y Acad Sci 1985; 446: 368-384. (Pubitemid 16238580)
-
(1985)
Annals of the New York Academy of Sciences
, vol.VOL. 446
, pp. 368-384
-
-
Scherphof, G.L.1
Dijkstra, J.2
Spanjer, H.H.3
-
27
-
-
0029019120
-
Fusion of cationic liposomes with mammalian cells occurs after endocytosis
-
Wrobel I, Collins D. Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochim Biophys Acta 1995; 1235: 296-304.
-
(1995)
Biochim Biophys Acta
, vol.1235
, pp. 296-304
-
-
Wrobel, I.1
Collins, D.2
|