Advances in simultaneous DSC-FTIR microspectroscopy for rapid solid-state chemical stability studies: Some dipeptide drugs as examples

Advanced Drug Delivery Reviews

Volumn 64, Issue 5, 2012, Pages 461-478

  Lin, Shan Yang ^a   Wang, Shun Li ^b  

^a YUANPEI UNIVERSITY   (Taiwan)

^b NATIONAL CHIAYI UNIVERSITY   (Taiwan)

Author keywords

Dehydration; Diketopiperazines; Dipeptides; DSC; DSC FTIR; Intramolecular cyclization; Solid state chemistry; Stability

Indexed keywords

DI-PEPTIDES; DIKETOPIPERAZINES; DSC; DSC-FTIR; INTRAMOLECULAR CYCLIZATIONS; SOLID STATE CHEMISTRY;

CONVERGENCE OF NUMERICAL METHODS; DEHYDRATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG PRODUCTS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; PEPTIDES; STABILITY; SUGAR SUBSTITUTES;

DRUG DOSAGE;

ASPARTAME; DIPEPTIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL MALEATE; EUDRAGIT; LISINOPRIL; MOEXIPRIL; PIPERAZINEDIONE; QUINAPRIL;

ABSORPTION; AQUEOUS SOLUTION; CONGESTIVE HEART FAILURE; CRYSTALLIZATION; CYCLIZATION; DEGRADATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DESIGN; DRUG FORMULATION; DRUG STABILITY; DRUG STRUCTURE; EVAPORATION; HEAT TREATMENT; HYDROLYSIS; HYPERTENSION; INFRARED SPECTROSCOPY; LIQUID; MICROSPECTROSCOPY; PHASE TRANSITION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; SHELF LIFE; SOLID; SOLID STATE; SPECTROSCOPY; TEMPERATURE DEPENDENCE; THERMODYNAMICS; THERMOGRAVIMETRY; THERMOSTABILITY; X RAY POWDER DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; DIKETOPIPERAZINES; DIPEPTIDES; DRUG STABILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84862796019     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2012.01.009     Document Type: Review

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