Madecassoside suppresses migration of fibroblasts from keloids: Involvement of p38 kinase and PI3K signaling pathways

Burns

Volumn 38, Issue 5, 2012, Pages 677-684

  Song, Jie ^a   Xu, Huan ^a   Lu, Qian ^a   Xu, Zhao ^a   Bian, Difei ^a   Xia, Yufeng ^a   Wei, Zhifeng ^a   Gong, Zhunan ^b   Dai, Yue ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING NORMAL UNIVERSITY   (China)

Author keywords

Cofilin; Fibroblast; Keloid; Madecassoside; MAPK; Migration; PI3K

Indexed keywords

COFILIN; F ACTIN; FLUORESCEIN ISOTHIOCYANATE; MADECASSOSIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHALLOIDIN; PHOSPHATIDYLINOSITOL 3 KINASE; TRITERPENOID; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; CELL MIGRATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG EFFECT; EAR LOBE; FIBROBLAST; HUMAN; HUMAN CELL; KELOID; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIN CYTOSKELETON; ANALYSIS OF VARIANCE; CELL MOVEMENT; CELLS, CULTURED; COFILIN 1; FIBROBLASTS; HUMANS; KELOID; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 13; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT EXTRACTS; SIGNAL TRANSDUCTION; TRITERPENES; WOUND HEALING;

EID: 84862792141     PISSN: 03054179     EISSN: 18791409     Source Type: Journal    
DOI: 10.1016/j.burns.2011.12.017     Document Type: Article

References (31)

1. C.P. Lim, T.T. Phan, I.J. Lim, and X. Cao Stat3 contributes to keloid pathogenesis via promoting collagen production, cell proliferation and migration Oncogene 25 2006 5416 5425
2. B. Cosman, G.F. Crikelair, J.C. Gaulin, and R. Lattes The surgical treatment of keloids Plast Reconstr Surg 27 1961 335 338
3. A. Ohtsuru, H. Yoshimoto, H. Ishihara, H. Namba, and S. Yamashita Insulin-like growth factor-I (IGF-I)/IGF-I receptor axis and increased invasion activity of fibroblasts in keloid Endocr J 47 Suppl 2000 S41 S44
4. T.S. Alster, and E.L. Tanzi Hypertrophic scars and keloids: etiology and management Am J Clin Dermatol 4 2003 235 243
5. A.D. Widgerow, L.A. Chait, R. Stals, and P.J. Stals New innovations in scar management Aesthetic Plast Surg 24 2000 227 234
6. J.P. Bosse, J. Papillon, G. Frenette, J. Dansereau, M. Cadotte, and J. Le Lorier Clinical study of a new antikeloid agent Ann Plast Surg 3 1979 13 21
7. Y. Chen, L.P. Qin, H.C. Zheng, Y.C. Rui, Q.Y. Zhang, and Q.M. Zheng Effects of Centella asiatica total triterpene fractions on endocrine function in depression rats Acad J Sec Mil Med Univ 23 2002 1224 1226
8. J. Song, Y. Dai, D.F. Bian, H.F. Zhang, X.X. Xu, and Y.F. Xia Madecassoside induces apoptosis of keloid fibroblasts via a mitochondrial- dependent pathway Drug Dev Res 72 2011 315 322
9. J.H. Sampson, A. Raman, G. Karlsen, H. Navsaria, and I.M. Leigh In vitro keratinocyte antiproliferant effect of Centella asiatica extract and triterpenoid saponins Phytomedicine 8 2001 230 235
10. W. Cao, X.Q. Li, X.N. Zhang, Y. Hou, A.G. Zeng, and Y.H. Xie Madecassoside suppresses LPS-induced TNF-alpha production in cardiomyocytes through inhibition of ERK, p38, and NF-kappaB activity Int Immunopharmacol 10 2010 723 729
11. L.L. Zhang, H.S. Wang, and Q.Q. Yao Chemical constituents from whole plant of Centella asiatica Chin Trad Herbal Drugs 36 2005 1761 1763
12. S. Blazer, E. Khankin, Y. Segev, R. Ofir, M. Yalon-Hacohen, and Z. Kra-Oz High glucose-induced replicative senescence: point of no return and effect of telomerase Biochem Biophys Res Commun 296 2002 93 101
13. J. Hu, and A.S. Verkman Increased migration and metastatic potential of tumor cells expressing aquaporin water channels FASEB J 20 2006 1892 1894
14. C. Moratha, H. Reuterb, V. Simona, E. Krautkramera, W. Muranyia, and V. Schwengera Effects of mycophenolic acid on human fibroblast proliferation, migration and adhesion in vitro and in vivo Am J Transplant 8 2008 1786 1797
15. K. Arii, Y. Kumon, K. Sugahara, K. Nakatani, Y. Ikeda, and T. Suehiro Edaravone inhibits collagen-induced arthritis possibly through suppression of nuclear factor-kappa B Mol Immunol 45 2008 463 469
16. I.J. Lim, T.T. Phan, E.K. Tan, T.T. Nguyen, E. Tran, and M.T. Longaker Synchronous activation of ERK and phosphatidylinositol 3-kinase pathways is required for collagen and extracellular matrix production in keloids J Biol Chem 278 2003 40851 40858
17. L. Satish, M. Babu, K.T. Tran, P.A. Hebda, and A. Wells Keloid fibroblast responsiveness to epidermal growth factor and activation of downstream intracellular signaling pathways Wound Repair Regen 12 2004 183 192
18. Y.R. Kuo, W.S. Wu, S.F. Jeng, H.C. Huang, K.D. Yang, and J.M. Sacks Activation of ERK and p38 kinase mediated keloid fibroblast apoptosis after flashlamp pulsed-dye laser treatment Lasers Surg Med 36 2005 31 37
19. G.P. Yang, I.J. Lim, T.T. Phan, H.P. Lorenz, and M.T. Longaker From scarless fetal wounds to keloids: molecular studies in wound healing Wound Repair Regen 11 2003 411 418
20. H.R. Dawe, L.S. Minamide, J.R. Bamburg, and L.P. Cramer ADF/cofilin controls cell polarity during fibroblast migration Curr Biol 13 2003 252 257
21. A. Gohla, and G.M. Bokoch 14-3-3 regulates actin dynamics by stabilizing phosphorylated cofilin Curr Biol 12 2002 1704 1710
22. C.M. Dreiza, C.M. Brophy, P. Komalavilas, E.J. Furnish, L. Joshi, and M.A. Pallero Transducible heat shock protein 20 (HSP20) phosphopeptide alters cytoskeletal dynamics FASEB J 19 2005 261 263
23. J.R. Bamburg, A. McGough, and S. Ono Putting a new twist on actin: ADF/cofilins modulate actin dynamics Trends Cell Biol 9 1999 364 370
24. M. Nishita, H. Aizawa, and K. Mizuno Stromal cell-derived factor 1alpha activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis Mol Cell Biol 22 2002 774 783
25. G. Uchida, K. Yoshimura, Y. Kitano, M. Okazaki, and K. Harii Tretinoin reverses upregulation of matrix metalloproteinase-13 in human keloid-derived fibroblasts Exp Dermatol 12 Suppl 2 2003 35 42
26. M. Vaalamo, L. Mattila, N. Johansson, A.L. Kariniemi, M.L. Karjalainen-Lindsberg, and V.M. Kähäri Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds Invest Dermatol 109 1997 96 101
27. A.P. Kelly Medical and surgical therapies for keloids Dermatol Ther 17 2004 212 218
28. M. Calderon, W.T. Lawrence, and A.J. Banes Increased proliferation in keloid fibroblasts wounded in vitro J Surg Res 61 1996 343 347
29. T.T. Phan, I.J. Lim, S.Y. Chan, E.K. Tan, S.T. Lee, and M.T. Longaker Suppression of transforming growth factor beta/smad signaling in keloid-derived fibroblasts by quercetin: implications for the treatment of excessive scars J Trauma 57 2004 1032 1037
30. W. Xia, M.T. Longaker, and G.P. Yang P38 MAP kinase mediates transforming growth factor-beta2 transcription in human keloid fibroblasts Am J Physiol Regul Integr Comp Physiol 290 2006 R501 R508
31. G. Meyer, B. Kim, C. van Golen, and E.L. Feldman Cofilin activity during insulin-like growth factor I-stimulated neuroblastoma cell motility Cell Mol Life Sci 62 2005 461 470