Synaptic vesicles are capable of synthesizing the VGLUT substrate glutamate from α-ketoglutarate for vesicular loading

Journal of Neurochemistry

Volumn 121, Issue 2, 2012, Pages 184-196

  Takeda, Kouji ^a   Ishida, Atsuhiko ^a,b   Takahashi, Kento ^b   Ueda, Tetsufumi ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Biosynthesis; GOT; Local synthesis; Neurotransmitter; Precursor

Indexed keywords

2 OXOGLUTARIC ACID; 2,3 PYRAZINEDICARBOXYLIC ACID; ASPARTATE AMINOTRANSFERASE; ASPARTIC ACID; BAFILOMYCIN; DICARBOXYLIC ACID; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER;

AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; MOLECULAR DYNAMICS; NERVE ENDING; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; SYNAPSE VESICLE;

ANIMALS; ASPARTATE AMINOTRANSFERASES; ASPARTIC ACID; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; GLUTAMATE DEHYDROGENASE; GLUTAMIC ACID; GLUTAMINASE; INDICATORS AND REAGENTS; KETOGLUTARIC ACIDS; MALE; MITOCHONDRIA; PROTON-TRANSLOCATING ATPASES; RATS; SUBCELLULAR FRACTIONS; SYNAPTIC VESICLES; SYNAPTOSOMES; VESICULAR TRANSPORT PROTEINS;

EID: 84862790096     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07684.x     Document Type: Article

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