Cytosolic, but not mitochondrial, oxidative stress is a likely contributor to cardiac hypertrophy resulting from cardiac specific GLUT4 deletion in mice

FEBS Journal

Volumn 279, Issue 4, 2012, Pages 599-611

  Li, Yan ^a   Wende, Adam R ^a   Nunthakungwan, Orathai ^a   Huang, Yujia ^a   Hu, Eric ^a   Jin, Huifeng ^a   Boudina, Sihem ^a   Abel, E Dale ^a   Jalili, Thunder ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

antioxidant; cardiac hypertrophy; GLUT4; mitochondria; p67phox; ROS

Indexed keywords

GLUTATHIONE; GLYCOGEN SYNTHASE KINASE 3BETA; OXIDOREDUCTASE; P67PHOX PROTEIN; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; THIOREDOXIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GLUCOSE TRANSPORTER 4 GENE; HEART VENTRICLE HYPERTROPHY; KNOCKOUT GENE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN TRANSPORT;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; BODY WEIGHT; CARDIOMEGALY; CYCLIC N-OXIDES; CYTOSOL; GLUCOSE TRANSPORTER TYPE 4; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MALONDIALDEHYDE; METALLOPORPHYRINS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MYOCARDIUM; OXIDATIVE STRESS; PHOSPHOPROTEINS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SPIN LABELS; TIME FACTORS;

MUS;

EID: 84862788366     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08450.x     Document Type: Article

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