Chronic exposure to contaminated drinking water stimulates PPAR expression in mice livers

Chemosphere

Volumn 88, Issue 4, 2012, Pages 407-412

  Shi, Peng ^a   Zhang, Xu Xiang ^a   Zhang, Zongyao ^a   Zhang, Yan ^a   Wu, Bing ^a   Cheng, Shupei ^a   Li, Aimin ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Drinking water; Hepatotoxicity; Microarray; Peroxisome proliferator activated receptors; Water pollution; Yangtze River

Indexed keywords

CYTOLOGY; HEALTH RISKS; MAMMALS; MICROARRAYS; RISK ASSESSMENT; RIVER POLLUTION; WATER POLLUTION;

CONTAMINATED DRINKING WATER; ENZYME LINKED IMMUNOSORBENT ASSAY; HEPATOTOXICITY; IMMUNOHISTOCHEMICAL STAINING; METABOLIC PATHWAYS; MICROARRAY ANALYSIS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; YANGTZE RIVER;

POTABLE WATER;

DRINKING WATER; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TAP WATER;

ARRAY; BIOASSAY; BIOMARKER; DRINKING WATER; ENZYME ACTIVITY; GENE EXPRESSION; HISTOPATHOLOGY; POLLUTION EFFECT; POLLUTION EXPOSURE; RODENT; TOXICITY; WATER POLLUTION;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROL GROUP; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEALTH HAZARD; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER; LIVER TOXICITY; LONG TERM EXPOSURE; MALE; METABOLISM; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; ORGAN WEIGHT; PROTEIN EXPRESSION; STAINING; WATER CONTAMINATION;

CHINA; YANGTZE RIVER;

MUS;

EID: 84862788111     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2012.02.055     Document Type: Article

References (46)

1. Arzuaga X., Ren N., Stromberg A., Black E.P., Arsenescu V., Cassis L.A., Majkova Z., Toborek M., Hennig B. Induction of gene pattern changes associated with dysfunctional lipid metabolism induced by dietary fat and exposure to a persistent organic pollutant. Toxicol. Lett. 2009, 189:96-101.
2. Berger J., Moller D.E. The mechanisms of action of PPARs. Annu. Rev. Med. 2002, 53:409-435.
3. Bradford B.U., Lock E.F., Kosyk O., Kim S., Uehara T., Harbourt D., DeSimone M., Threadgill D.W., Tryndyak V., Pogribny I.P., Bleyle L., Koop D.R., Rusyn I. Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice. Toxicol. Sci. 2011, 120:206-217.
4. Cariello N.F., Romach E.H., Colton H.M., Ni H., Yoon L., Falls J.G., Casey W., Creech D., Anderson S.P., Benavides G.R., Hoivik D.J., Brown R., Miller R.T. Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver. Toxicol. Sci. 2005, 88:250-264.
5. Currie R.A., Orphanides G., Moggs J.G. Mapping molecular responses to xenoestrogens through Gene Ontology and pathway analysis of toxicogenomic data. Reprod. Toxicol. 2005, 20:433-440.
6. Dai J., Zhang H., Shi Z., Liu Y., Wei Y. Lipid homeostasis and oxidative stress in the liver of male rats exposed to perfluorododecanoic acid. Toxicol. Appl. Pharmacol. 2008, 227:16-25.
7. Dreyer C., Krey G., Keller H., Givel F., Helftenbein G., Wahli W. Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors. Cell 1992, 68:879-887.
8. Edgar A.D., Tomkiewicz C., Costet P., Legendre C., Aggerbeck M., Bouguet J., Staels B., Guyomard C., Pineau T., Barouki R. Fenofibrate modifies transaminase gene expression via a peroxisome proliferator activated receptor alpha-dependent pathway. Toxicol. Lett. 1998, 98:13-23.
9. Finck B.N., Lehman J.J., Leone T.C., Welch M.J., Bennett M.J., Kovacs A., Han X.L., Gross R.W., Kozak R., Lopaschuk G.D., Kelly D.P. The cardiac phenotype induced by PPAR alpha overexpression mimics that caused by diabetes mellitus. J. Clin. Invest. 2002, 109:121-130.
10. Gallagher L.G., Webster T.F., Aschengrau A., Vieira V.M. Using residential history and groundwater modeling to examine drinking water exposure and breast cancer. Environ. Health Perspect. 2010, 118:749-755.
11. Gbaguidi G.F., Agellon L.B. The inhibition of the human cholesterol 7 alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer. Nucleic Acids Res. 2004, 32:1113-1121.
12. Gordon S.C. Toxicological evaluation of ammonium 4,8-dioxa-3H-perfluorononanoate, a new emulsifier to replace ammonium perfluorooctanoate in fluoropolymer manufacturing. Regul. Toxicol. Pharm. 2011, 59:64-80.
13. He H., Hu G.J., Sun C., Chen S.L., Yang M.N., Li J., Zhao Y., Wang H. Trace analysis of persistent toxic substances in the main stream of Jiangsu section of the Yangtze River, China. Environ. Sci. Pollut. Res. 2011, 18:638-648.
14. Issemann I., Green S. Activation of a member of the steroid-hormone receptor superfamily by peroxisome proliferators. Nature 1990, 347:645-650.
15. Kersten S., Desvergne B., Wahli W. Roles of PPARs in health and disease. Nature 2000, 405:421-424.
16. Kim H.J., Rakwal R., Shibato J., Iwahashi H., Choi J.S., Kim D.H. Effect of textile wastewaters on Saccharomyces cerevisiae using DNA microarray as a tool for genome-wide transcriptomics analysis. Water Res. 2006, 40:1773-1782.
17. Kim J.H., Yamaguchi K., Lee S.H., Tithof P.K., Sayler G.S., Yoon J.H., Baek S.J. Evaluation of polycyclic aromatic hydrocarbons in the activation of early growth response-1 and peroxisome proliferator activated receptors. Toxicol. Sci. 2005, 85:585-593.
18. Klaunig J.E., Babich M.A., Baetcke K.P., Cook J.C., Corton J.C., David R.M., DeLuca J.G., Lai D.Y., McKee R.H., Peters J.M., Roberts R.A., Fenner-Crisp P.A. PPAR alpha agonist-induced rodent tumors: modes of action and human relevance. Crit. Rev. Toxicol. 2003, 33:655-780.
19. Lampen A., Zimnik S., Nau H. Teratogenic phthalate esters and metabolites activate the nuclear receptors PPARs and induce differentiation of F9 cells. Toxicol. Appl. Pharmacol. 2003, 188:14-23.
20. Lapinskas P.J., Brown S., Leesnitzer L.M., Blanchard S., Swanson C., Cattley R.C., Corton J.C. Role of PPAR alpha in mediating the effects of phthalates and metabolites in the liver. Toxicology 2005, 207:149-163.
21. Lehmann J.M., Lenhard J.M., Oliver B.B., Ringold G.M., Kliewer S.A. Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J. Biol. Chem. 1997, 272:3406-3410.
22. Mardones P., Pilon A., Bouly M., Duran D., Nishimoto T., Arai H., Kozarsky K.F., Altayo M., Miquel J.F., Luc G., Clavey V., Staels B., Rigotti A. Fibrates down-regulate hepatic scavenger receptor class B type I protein expression in mice. J. Biol. Chem. 2003, 278:7884-7890.
23. Markowski V.P., Currie D., Reeve E.A., Thompson D., Wise J.P. Tissue-specific and dose-related accumulation of arsenic in mouse offspring following maternal consumption of arsenic-contaminated water. Basic Clin. Pharmacol. Toxicol. 2011, 108:326-332.
24. Moens L.N., Smolders R., van der Ven K., van Remortel P., Del-Favero J., De Coen W.M. Effluent impact assessment using microarray-based analysis in common carp: a systems toxicology approach. Chemosphere 2007, 67:2293-2304.
25. Oikari A., Lahti M., Merilainen P., Afanasyev S., Krasnov A. Do historical sediments of pulp and paper industry contribute to the exposure of fish caged in receiving waters?. J. Environ. Monit. 2010, 12:1045-1054.
26. Peters J.M., Cattley R.C., Gonzalez F.J. Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643. Carcinogenesis 1997, 18:2029-2033.
27. Rezen T., Viola T., Lovgren-Sandblom A., Bjorkhem I., Meyer U.A., Rozman D. Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers. BMC Genom. 2009, 10:384-399.
28. Richardson S.D., Plewa M.J., Wagner E.D., Schoeny R., DeMarini D.M. Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research. Mutat. Res. Rev. Mutat. Res. 2007, 636:178-242.
29. Sarraf P., Mueller E., Jones D., King F.J., DeAngelo D.J., Partridge J.B., Holden S.A., Chen L.B., Singer S., Fletcher C., Spiegelman B.M. Differentiation and reversal of malignant changes in colon cancer through PPAR gamma. Nat. Med. 1998, 4:1046-1052.
30. Shimada T., Nakanishi T., Toyama A., Yamauchi S., Kanzaki A., Fujiwake H., Sato T.A., Ikegawa M. Potential implications for monitoring serum bile acid profiles in circulation with serum proteome for carbon tetrachloride-induced liver injury/regeneration model in mice. J. Proteome Res. 2010, 9:4490-4500.
31. Sun J., Cheng S.P., Li A.M., Zhang R., Wu B., Zhang Y., Zhang X.X. Integration of gene chip and topological network techniques to screen a candidate biomarker gene (CBG) for predication of the source water carcinogenesis risks on mouse Mus musculus. Ecotoxicology 2011, 20:1026-1032.
32. Thompson J., Eaglesham G., Mueller J. Concentrations of PFOS, PFOA and other perfluorinated alkyl acids in Australiandrinkingwater. Chemosphere 2011, 83:1320-1325.
33. Valcárcel Y., Gonzalez Alonso S., Rodriguez-Gil J.L., Catala M., Romo Maroto R. Analysis of the presence of cardiovascular and analgesic/anti-inflammatory/antipyretic pharmaceuticals in river- and drinking-water of the Madrid Region in Spain. Chemosphere 2011, 82:1062-1071.
34. Verheyen G.R., Nuijten J.M., Van Hummelen P., Schoeters G.R. Microarray analysis of the effect of diesel exhaust particles on in vitro cultured macrophages. Toxicol. in Vitro 2004, 18:377-391.
35. Welsch F., Nemec M.D., Lawrence W.B. Two-generation reproductive toxicity study of resorcinol administered via drinking water to Crl: CD(SD) rats. Int. J. Toxicol. 2008, 27:43-57.
36. Willson T.M., Lambert M.H., Kliewer S.A. Peroxisome proliferator-activated receptor gamma and metabolic disease. Annu. Rev. Biochem. 2001, 70:341-367.
37. Woods C.G., Heuvel J.P.V., Rusyn I. Genomic profiling in nuclear receptor-mediated toxicity. Toxicol. Pathol. 2007, 35:474-494.
38. Wu B., Zhang Y., Zhao D.Y., Zhang X.X., Kong Z.M., Cheng S.P. Gene expression profiles in liver of mouse after chronic exposure to drinking water. J. Appl. Toxicol. 2009, 29:569-577.
39. Ye H., Zhou C.H., Zeng X.X. Investigation of pollution characteristics of polychlorinated biphenyls in the typical drinking water sources in Jiangsu Province, China. Environ. Monit. Assess. 2009, 158:573-579.
40. Yuan X., Yan S., Zhao J., Shi D., Yuan B., Dai W., Jiao B., Zhang W., Miao M. Lipid metabolism and peroxisome proliferator-activated receptor signaling pathways participate in late-phase liver regeneration. J. Proteome Res. 2011, 10:1179-1190.
41. Zhang R., Cheng S., Li A., Sun J., Zhang Y., Zhang X. Genome-wide screening of indicator genes for assessing the potential carcinogenic risk of Nanjing city drinking water. Ecotoxicology 2011, 20:1-8.
42. Zhang X.X., Zhang Z.Y., Fu Z.Y., Wang T., Qin W.D., Xu L.Z., Cheng S.P., Yang L.Y. Stimulation effect of microcystin-LR on matrix metalloproteinase-2/-9 expression in mouse liver. Toxicol. Lett. 2010, 199:377-382.
43. Zhang Y., Wu B., Zhang Z.-Y., Cheng S.-P. A metabonomic analysis on health effects of drinking water on male mice (Mus musculus). J. Hazard. Mater. 2011, 190:515-519.
44. Zhang Y., Zhao D.Y., Wu B., Hu F., Kong J., Zhang X.X., Li M., Cui Y.B., Cheng S.P. Effects of the Yangtze River source of drinking water on metabolites of Mus musculus. Ecotoxicology 2009, 18:722-728.
45. Zhao D.Y., Cheng S.P., Wu B., Zhang Y., Zhang X.X., Li W.X., Cui Y.B. Toxicity of the Yangtze River source of drinking water on reproductive system of male mice (Mus musculus). Ecotoxicology 2009, 18:729-735.
46. Zhou G.P., Wen S.P., Liu Y.W., Li R.R., Zhong X.Y., Feng L., Wang L., Cao B.Y. Development of a DNA microarray for detection and identification of Legionella pneumophila and ten other pathogens in drinking water. Int. J. Food Microbiol. 2011, 145:293-300.