Clinical significance of serological biomarkers and neuropsychological performances in patients with temporal lobe epilepsy

BMC Neurology

Volumn 12, Issue , 2012, Pages

  Chang, Chiung Chih ^a,b   Lui, Chun Chung ^a   Lee, Chen Chang ^a   Chen, Shang Der ^a   Chang, Wen Neng ^a   Lu, Cheng Hsien ^a   Chen, Nai Ching ^a   Chang, Alice Y W ^a   Chan, Samuel H H ^a   Chuang, Yao Chung ^a,b  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Biomarkers; Gray matter atrophy; Heat shock proteins; Neuropsychological performances; Temporal lobe epilepsy

Indexed keywords

BIOLOGICAL MARKER; CELL NUCLEUS DNA; HEAT SHOCK PROTEIN 70; MITOCHONDRIAL DNA; NEURON SPECIFIC ENOLASE; PROTEIN S100B; ENOLASE; NADH DEHYDROGENASE SUBUNIT 2, HUMAN; NERVE GROWTH FACTOR; PROTEIN S 100; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; S 100 CALCIUM BINDING PROTEIN BETA SUBUNIT; S-100 CALCIUM-BINDING PROTEIN BETA SUBUNIT;

ADULT; ARTICLE; BRAIN ATROPHY; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; CORRELATION ANALYSIS; DEPTH PERCEPTION; DISEASE DURATION; EXECUTIVE FUNCTION; FEMALE; GRAY MATTER; HIPPOCAMPUS; HUMAN; LANGUAGE ABILITY; MALE; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; PARAHIPPOCAMPAL GYRUS; PROBLEM SOLVING; PUTAMEN; RECALL; SPEECH; SUPPLEMENTARY MOTOR AREA; TEMPORAL LOBE EPILEPSY; THALAMUS; THINKING; VERBAL MEMORY; VISUAL MEMORY; VOXEL BASED MORPHOMETRY; BLOOD; CASE CONTROL STUDY; CELL NUCLEUS; COGNITIVE DEFECT; COHORT ANALYSIS; CYTOLOGY; ELECTROENCEPHALOGRAPHY; GENETICS; METABOLISM; MIDDLE AGED; NONPARAMETRIC TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PLASMA; THREE DIMENSIONAL IMAGING;

ADULT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CELL NUCLEUS; COGNITION DISORDERS; COHORT STUDIES; ELECTROENCEPHALOGRAPHY; EPILEPSY, TEMPORAL LOBE; FEMALE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMAGING, THREE-DIMENSIONAL; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NADH DEHYDROGENASE; NERVE GROWTH FACTORS; NEUROPSYCHOLOGICAL TESTS; PHOSPHOPYRUVATE HYDRATASE; PLASMA; S100 PROTEINS; STATISTICS, NONPARAMETRIC;

EID: 84862787810     PISSN: None     EISSN: 14712377     Source Type: Journal    
DOI: 10.1186/1471-2377-12-15     Document Type: Article

References (42)

1. Engel J. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology. Epilepsia 2001, 42(6):796-803. 10.1046/j.1528-1157.2001.10401.x, 11422340.
2. Engel J. Report of the ILAE classification core group. Epilepsia 2006, 47(9):1558-1568. 10.1111/j.1528-1167.2006.00215.x, 16981873.
3. Thom M, Mathern GW, Cross JH, Bertram EH. Mesial temporal lobe epilepsy: How do we improve surgical outcome?. Ann Neurol 2010, 68(4):424-434. 10.1002/ana.22142, 2966035, 20976764.
4. Tellez-Zenteno JF, Hernandez Ronquillo L, Moien-Afshari F, Wiebe S. Surgical outcomes in lesional and non-lesional epilepsy: a systematic review and meta-analysis. Epilepsy Res 2010, 89(2-3):310-318. 10.1016/j.eplepsyres.2010.02.007, 20227852.
5. Friedman DE, Gilliam FG. Seizure-related injuries are underreported in pharmacoresistant localization-related epilepsy. Epilepsia 2010, 51(1):43-47. 10.1111/j.1528-1167.2009.02170.x, 20618399.
6. Chen DK, So YT, Fisher RS. Use of serum prolactin in diagnosing epileptic seizures: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurol 2005, 65(5):668-675.
7. Cui J, Wang Y, Dong Q, Wu S, Xiao X, Hu J, Chai Z, Zhang Y. Morphine protects against intracellular amyloid toxicity by inducing estradiol release and upregulation of Hsp70. J Neurosci 2011, 31(45):16227-16240. 10.1523/JNEUROSCI.3915-11.2011, 22072674.
8. Rabinowicz AL, Correale JD, Bracht KA, Smith TD, DeGiorgio CM. Neuron-specific enolase is increased after nonconvulsive status epilepticus. Epilepsia 1995, 36(5):475-479. 10.1111/j.1528-1157.1995.tb00489.x, 7614925.
9. Thom M, Seetah S, Sisodiya S, Koepp M, Scaravilli F. Sudden and unexpected death in epilepsy (SUDEP): evidence of acute neuronal injury using HSP-70 and c-Jun immunohistochemistry. Neuropathol Appl Neurobiol 2003, 29(2):132-143. 10.1046/j.1365-2990.2003.00452.x, 12662321.
10. DeGiorgio CM, Correale JD, Gott PS, Ginsburg DL, Bracht KA, Smith T, Boutros R, Loskota WJ, Rabinowicz AL. Serum neuron-specific enolase in human status epilepticus. Neurol 1995, 45(6):1134-1137.
11. Buttner T, Lack B, Jager M, Wunsche W, Kuhn W, Muller T, Przuntek H, Postert T. Serum levels of neuron-specific enolase and s-100 protein after single tonic-clonic seizures. J Neurol 1999, 246(6):459-461. 10.1007/s004150050383, 10431771.
12. Lu C, Li J, Sun W, Feng L, Li L, Liu A, Mao W, Wei H, Gao L, Zhang X, et al. Elevated plasma S100B concentration is associated with mesial temporal lobe epilepsy in Han Chinese: a case-control study. Neurosci Lett 2010, 484(2):139-142. 10.1016/j.neulet.2010.08.036, 20727940.
13. Griffin WS, Yeralan O, Sheng JG, Boop FA, Mrak RE, Rovnaghi CR, Burnett BA, Feoktistova A, Van Eldik LJ. Overexpression of the neurotrophic cytokine S100 beta in human temporal lobe epilepsy. J Neurochem 1995, 65(1):228-233.
14. Palmio J, Keranen T, Alapirtti T, Hulkkonen J, Makinen R, Holm P, Suhonen J, Peltola J. Elevated serum neuron-specific enolase in patients with temporal lobe epilepsy: a video-EEG study. Epilepsy Res 2008, 81(2-3):155-160. 10.1016/j.eplepsyres.2008.05.006, 18595663.
15. Hashimoto K, Watanabe K, Nishimura T, Iyo M, Shirayama Y, Minabe Y. Behavioral changes and expression of heat shock protein hsp-70 mRNA, brain-derived neurotrophic factor mRNA, and cyclooxygenase-2 mRNA in rat brain following seizures induced by systemic administration of kainic acid. Brain Res 1998, 804(2):212-223. 10.1016/S0006-8993(98)00708-2, 9757041.
16. Ryufuku M, Toyoshima Y, Kitaura H, Zheng Y, Fu YJ, Miyahara H, Murakami H, Masuda H, Kameyama S, Takahashi H, et al. Hypertrophy of hippocampal end folium neurons in patients with mesial temporal lobe epilepsy. Neuropathology 2011, 31(5):476-485. 10.1111/j.1440-1789.2010.01191.x, 21276083.
17. Yang T, Hsu C, Liao W, Chuang JS. Heat shock protein 70 expression in epilepsy suggests stress rather than protection. Acta Neuropathol 2008, 115(2):219-230. 10.1007/s00401-007-0297-3, 17929041.
18. Tsai NW, Lin TK, Chen SD, Chang WN, Wang HC, Yang TM, Lin YJ, Jan CR, Huang CR, Liou CW, et al. The value of serial plasma nuclear and mitochondrial DNA levels in patients with acute ischemic stroke. Clin Chim Acta 2011, 412(5-6):476-479. 10.1016/j.cca.2010.11.036, 21130757.
19. Lu CH, Chang WN, Tsai NW, Chuang YC, Huang CR, Wang HC. The value of serial plasma nuclear and mitochondrial DNA levels in adult community-acquired bacterial meningitis. QJM 2010, 103(3):169-175. 10.1093/qjmed/hcp201, 20129945.
20. Pitkanen A, Sutula TP. Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy. Lancet Neurol 2002, 1(3):173-181. 10.1016/S1474-4422(02)00073-X, 12849486.
21. Andersson-Roswall L, Engman E, Samuelsson H, Malmgren K. Cognitive outcome 10 years after temporal lobe epilepsy surgery: a prospective controlled study. Neurol 2010, 74(24):1977-1985.
22. Baxendale S, Heaney D, Thompson PJ, Duncan JS. Cognitive consequences of childhood-onset temporal lobe epilepsy across the adult lifespan. Neurol 2010, 75(8):705-711.
23. Keller SS, Roberts N. Voxel-based morphometry of temporal lobe epilepsy: an introduction and review of the literature. Epilepsia 2008, 49(5):741-757. 10.1111/j.1528-1167.2007.01485.x, 18177358.
24. Yang T, Zhou D, Stefan H. Why mesial temporal lobe epilepsy with hippocampal sclerosis is progressive: uncontrolled inflammation drives disease progression?. J Neurol Sci 2010, 296(1-2):1-6. 10.1016/j.jns.2010.06.002, 20663517.
25. Tan TY, Lu CH, Chuang HY, Lin TK, Liou CW, Chang WN, Chuang YC. Long-term antiepileptic drug therapy contributes to the acceleration of atherosclerosis. Epilepsia 2009, 50(6):1579-1586. 10.1111/j.1528-1167.2009.02024.x, 19292757.
26. Lo YM, Tein MS, Lau TK, Haines CJ, Leung TN, Poon PM, Wainscoat JS, Johnson PJ, Chang AM, Hjelm NM. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis. Am J Hum Genet 1998, 62(4):768-775. 10.1086/301800, 1377040, 9529358.
27. Chiu RW, Chan LY, Lam NY, Tsui NB, Ng EK, Rainer TH, Lo YM. Quantitative analysis of circulating mitochondrial DNA in plasma. Clin Chem 2003, 49(5):719-726. 10.1373/49.5.719, 12709361.
28. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001, 29(9):e45. 10.1093/nar/29.9.e45, 55695, 11328886.
29. Chang CC, Chang WN, Lui CC, Wang JJ, Chen CF, Lee YC, Chen SS, Lin YT, Huang CW, Chen C. Longitudinal study of carbon monoxide intoxication by diffusion tensor imaging with neuropsychiatric correlation. J Psychiatry Neurosci 2010, 35(2):115-125. 10.1503/jpn.090057, 2834793, 20184809.
30. Chang CC, Chang YY, Chang WN, Lee YC, Wang YL, Lui CC, Huang CW, Liu WL. Cognitive deficits in multiple system atrophy correlate with frontal atrophy and disease duration. Eur J Neurol 2009, 16(10):1144-1150. 10.1111/j.1468-1331.2009.02661.x, 19486137.
31. Chang CC, Lee YC, Chang WN, Chen SS, Lui CC, Chang HW, Liu WL, Wang YL. Damage of white matter tract correlated with neuropsychological deficits in carbon monoxide intoxication after hyperbaric oxygen therapy. J Neurotrauma 2009, 26(8):1263-1270. 10.1089/neu.2008.0619, 19317622.
32. Chang CC, Kramer JH, Lin KN, Chang WN, Wang YL, Huang CW, Lin YT, Chen C, Wang PN. Validating the Chinese version of the Verbal Learning Test for screening Alzheimer's disease. J Int Neuropsychol Soc 2010, 16(2):244-251. 10.1017/S1355617709991184, 20003579.
33. Ashburner J, Friston KJ. Voxel-based morphometry-the methods. NeuroImage 2000, 11(6 Pt 1):805-821.
34. Lanneau D, Wettstein G, Bonniaud P, Garrido C. Heat shock proteins: cell protection through protein triage. ScientificWorldJournal 2010, 10:1543-1552.
35. Ayala GX, Tapia R. HSP70 expression protects against hippocampal neurodegeneration induced by endogenous glutamate in vivo. Neuropharmacol 2008, 55(8):1383-1390.
36. Marshak DR. S100 beta as a neurotrophic factor. Prog Brain Res 1990, 86:169-181.
37. Pham N, Fazio V, Cucullo L, Teng Q, Biberthaler P, Bazarian JJ, Janigro D. Extracranial sources of S100B do not affect serum levels. PLoS One 2010, 5(9). e12691. doi:10.1371/journal.pone.0012691.
38. Steinhoff BJ, Tumani H, Otto M, Mursch K, Wiltfang J, Herrendorf G, Bittermann HJ, Felgenhauer K, Paulus W, Markakis E. Cisternal S100 protein and neuron-specific enolase are elevated and site-specific markers in intractable temporal lobe epilepsy. Epilepsy Res 1999, 36(1):75-82. 10.1016/S0920-1211(99)00026-1, 10463853.
39. Kleindienst A, Meissner S, Eyupoglu IY, Parsch H, Schmidt C, Buchfelder M. Dynamics of S100B release into serum and cerebrospinal fluid following acute brain injury. Acta Neurochir Suppl 2010, 106:247-250. 10.1007/978-3-211-98811-4_46, 19812958.
40. Leutmezer F, Wagner O, Baumgartner C. Serum s-100 protein is not a suitable seizure marker in temporal lobe epilepsy. Epilepsia 2002, 43(10):1172-1174. 10.1046/j.1528-1157.2002.50101.x, 12366732.
41. Palmio J, Peltola J, Vuorinen P, Laine S, Suhonen J, Keranen T. Normal CSF neuron-specific enolase and S-100 protein levels in patients with recent non-complicated tonic-clonic seizures. J Neurol Sci 2001, 183(1):27-31. 10.1016/S0022-510X(00)00478-0, 11166790.
42. Fournie GJ, Martres F, Pourrat JP, Alary C, Rumeau M. Plasma DNA as cell death marker in elderly patients. Gerontol 1993, 39(4):215-221.