Elevated serum neuron-specific enolase in patients with temporal lobe epilepsy: A video-EEG study

Epilepsy Research

Volumn 81, Issue 2-3, 2008, Pages 155-160

  Palmio, Johanna ^a,b   Keränen, Tapani ^b   Alapirtti, Tiina ^b   Hulkkonen, Janne ^b   Mäkinen, Riikka ^b   Holm, Päivi ^b   Suhonen, Jaana ^c   Peltola, Jukka ^b  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c Jokilaakso Hospital   (Finland)

Author keywords

Brain damage; Extratemporal lobe epilepsy; Neuron specific enolase; S 100 protein; Temporal lobe epilepsy; Video EEG monitoring

Indexed keywords

ANTICONVULSIVE AGENT; NEURON SPECIFIC ENOLASE; PROTEIN S 100;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; ARTICLE; BRAIN DAMAGE; CLINICAL ARTICLE; COMPLEX PARTIAL SEIZURE; ELECTROENCEPHALOGRAM; ENZYME BLOOD LEVEL; FEMALE; FRONTAL LOBE EPILEPSY; HOSPITAL PATIENT; HUMAN; MALE; MONOTHERAPY; NERVE CELL LESION; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; TEMPORAL LOBE EPILEPSY; TONIC CLONIC SEIZURE; VIDEORECORDING;

ADULT; ELECTROENCEPHALOGRAPHY; EPILEPSY, TEMPORAL LOBE; FEMALE; HUMANS; IMMUNOASSAY; MALE; MIDDLE AGED; PHOSPHOPYRUVATE HYDRATASE; S100 PROTEINS; STATISTICS, NONPARAMETRIC; TIME FACTORS; VIDEO RECORDING; YOUNG ADULT;

EID: 53449085281     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2008.05.006     Document Type: Article

References (32)

1. Araújo D., Santos A.C., Velasco T.R., Wichert-Ana L., Terra-Bustamante V.C., Alexandre Jr. V., Carlotti Jr. C.G., Assirati Jr. J.A., Machado H.R., Walz R., Leite J.P., and Sakamoto A.C. Volumetric evidence of bilateral damage in unilateral mesial temporal lobe epilepsy. Epilepsia 47 (2006) 1354-1359
2. Arts B., Peters M., Ponds R., Honig A., Menheere P., and van Os J. S100 and impact of ECT on depression and cognition. J. ECT 22 (2006) 206-212
3. Ben-Ari Y. Limbic seizures and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. Neuroscience 14 (1985) 375-403
4. Böttiger B.W., Möbes S., Glätzer R., Bauer H., Gries A., Bärtsch P., Motsch J., and Martin E. Astroglial protein S-100 is an early and sensitive marker of hypoxic brain damage and outcome after cardiac arrest in humans. Circulation 103 (2001) 2694-2698
5. Büttner T., Lack B., Jäger M., Wünsche W., Kuhn W., Müller T., Przuntek H., and Postert T. Serum levels of neuron-specific enolase and S-100 protein after single tonic-clonic seizures. J. Neurol. 246 (1999) 459-461
6. Casmiro M., Maitan S., De Pasquale F., Cova V., Scarpa E., Vignatelli L., and on behalf of the NSE Study Group. Cerebrospinal fluid and serum neuron-specific enolase concentrations in a normal population. Eur. J. Neurol. 12 (2005) 369-374
7. Cavazos J.E., Das I., and Sutula T.P. Neuronal loss induced in limbic pathways by kindling: evidence for induction of hippocampal sclerosis by repeated brief seizures. J. Neurosci. 14 (1994) 3106-3121
8. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia 22 (1981) 489-501
9. Correale J., Rabinowicz A.L., Heck C.N., Smith T.D., Loskota W.J., and DeGiorgio C.M. Status epilepticus increases CSF levels of neuron-specific enolase and alters the blood-brain barrier. Neurology 50 (1998) 1388-1391
10. DeGiorgio C.M., Correale J.D., Gott P.S., Ginsburg D.L., Bracht K.A., Smith T., Boutros R., Loskota W.J., and Rabinowicz A.L. Serum neuron-specific enolase in human status epilepticus. Neurology 45 (1995) 1134-1137
11. DeGiorgio C.M., Gott P.S., Rabinowicz A.L., Heck C.N., Smith T.D., and Correale J.D. Neuron-specific enolase, a marker of acute neuronal injury, is increased in complex partial status epilepticus. Epilepsia 37 (1996) 606-609
12. DeGiorgio C.M., Heck C.N., Rabinowicz A.L., Gott P.S., Smith T., and Correale J. Serum neuron-specific enolase in the major subtypes of status epilepticus. Neurology 52 (1999) 746-749
13. Dodrill C.B. Progressive cognitive decline in adolescents and adults with epilepsy. Prog. Brain Res. 135 (2002) 397-408
14. Hansen A., Jørgensen O.S., Bolwig T.G., and Barry D.I. Hippocampal kindling alters the concentration of glial fibrillary acidic protein and other marker proteins in rat brain. Brain Res. 531 (1990) 301-311
15. Leutmezer F., Wagner O., and Baumgartner C. Serum S-100 protein is not a suitable marker in temporal lobe epilepsy. Epilepsia 43 (2002) 1172-1174
16. Matthews J.N.S., Altman D.G., Campbell M.J., and Royston P. Analysis of serial measurements in medical research. BMJ 300 (1990) 230-235
17. Otto M., Wiltfang J., Mogge S., Tumani H., Pfahlberg A., and Steinhoff B. Changing levels of S-100 protein in serum after epileptic seizures. Epilepsia 39 suppl. 2 (1998) 73 (Abstract)
18. Palmio J., Peltola J., Vuorinen P., Laine S., Suhonen J., and Keränen T. Normal CSF neuron-specific enolase and S-100 protein levels in patients with recent non-complicated tonic-clonic seizures. J. Neurol. Sci. 183 (2001) 27-31
19. Pitkänen A., Nissinen J., Nairismägi J., Lukasiuk K., Grohn O.H., Miettinen R., and Kauppinen R. Progression of neuronal damage after status epilepticus and spontaneous seizures in a rat model of temporal lobe epilepsy. Prog. Brain Res. 135 (2002) 67-83
20. Pitkänen A., and Sutula T.P. Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy. Lancet Neurol. 1 (2002) 173-181
21. Rabinowicz A.L., Correale J., Boutros R.B., Couldwell W.T., Henderson C.W., and DeGiorgio C.M. Neuron-specific enolase is increased after single seizures during inpatient video/EEG monitoring. Epilepsia 37 (1996) 122-125
22. Rech T.H., Vieira S.R., Nagel F., Brauner J.S., and Scalco R. Serum neuron-specific enolase as early predictor of outcome after in-hospital cardiac arrest: a cohort study. Crit. Care 10 (2006) R133
23. Salmenperä T., Kälviäinen R., Partanen K., and Pitkänen A. Hippocampal and amygdaloid damage in partial epilepsy: a cross-sectional MRI study of 241 patients. Epilepsy Res. 46 (2001) 69-82
24. Salmenperä T., Könönen M., Roberts N., Vanninen R., Pitkänen A., and Kälviäinen R. Hippocampal damage in newly diagnosed focal epilepsy: a prospective study. Neurology 64 (2005) 62-68
25. Sutula T., Koch J., Golarai G., Watanabe Y., and McNamara J.O. NMDA receptor dependence of kindling and mossy fiber sprouting: evidence that the NMDA receptor regulates patterning of hippocampal circuits in the adult brain. J. Neurosci. 16 (1996) 7398-7406
26. Sutula T.P. Mechanisms of epilepsy progression: current theories and perspectives from neuroplasticity in adulthood and development. Epilepsy Res. 60 (2004) 161-171
27. Tumani H., Otto M., Gefeller O., Wiltfang J., Herrendorf G., Mogge S., and Steinhoff B.J. Kinetics of serum neuron-specific enolase and prolactin in patients after single epileptic seizures. Epilepsia 40 (1999) 713-718
28. Van Paesschen W., Connelly A., King M.D., Jackson G.D., and Duncan J.S. The spectrum of hippocampal sclerosis: a quantitative magnetic resonance imaging study. Ann. Neurol. 41 (1997) 41-51
29. Vos P.E., Lamers K.J.B., Hendriks J.C.M., van Haaren M., Beems T., Zimmerman C., van Geel W., de ReusF H., Biert J., and Verbeek M.M. Glial and neuronal proteins in serum predict outcome after severe traumatic brain injury. Neurology 62 (2004) 1303-1310
30. Willert C., Spitzer C., Kusserow S., and Runge U. Serum neuron-specific enolase, prolactin, and creatine kinase after epileptic and psychogenic non-epileptic seizures. Acta Neurol. Scand. 109 (2004) 318-323
31. Wunderlich M.T., Ebert A.D., Kratz T., Goertler M., Jost S., and Herrmann M. Early neurobehavioral outcome after stroke is related to release of neurobiochemical markers of brain damage. Stroke 30 (1999) 1190-1195
32. Young G.B. Status epilepticus and brain damage: pathology and pathophysiology. Adv. Neurol. 97 (2006) 217-220