Extracranial sources of S100B do not affect serum levels

PLoS ONE

Volumn 5, Issue 9, 2010, Pages 1-9

  Pham, Nancy ^a   Fazio, Vincent ^b   Cucullo, Luca ^b   Teng, Qingshan ^b   Biberthaler, Peter ^c   Bazarian, Jeffrey J ^d   Janigro, Damir ^a  

^a CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN S100B; PROTEIN S 100;

ADIPOSE TISSUE; ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD BRAIN BARRIER; BODY MASS; BRAIN; CHILD; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; MOLECULAR DYNAMICS; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; PROTEIN LOCALIZATION; SCHOOL CHILD; TISSUE DISTRIBUTION; TISSUE SPECIFICITY; WESTERN BLOTTING; BLOOD; BRAIN LEVEL; CHEMISTRY; METABOLISM; MIDDLE AGED; SKELETAL MUSCLE;

ADIPOSE TISSUE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BLOOD-BRAIN BARRIER; BODY MASS INDEX; BRAIN; BRAIN CHEMISTRY; CHILD; FEMALE; HUMANS; MALE; MIDDLE AGED; MUSCLE, SKELETAL; S100 PROTEINS; YOUNG ADULT;

EID: 77958607368     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012691     Document Type: Article

References (48)

1. Kanner AA, Marchi N, Fazio V, Mayberg MR, Koltz MT, et al. (2003) Serum S100beta: a noninvasive marker of blood-brain barrier function and brain lesions. Cancer 97: 2806-2813.
2. Marchi N, Rasmussen PA, Kapural M, Fazio V, Cavaglia M, et al. (2003) Peripheral markers of brain damage and blood-brain barrier dysfunction. Restor Neurol Neurosci 21: 109-121.
3. Blyth BJ, Farhavar A, Gee C, Hawthorn B, He H, et al. (2009) Validation of serum markers for blood-brain barrier disruption in traumatic brain injury. J Neurotrauma 26: 1497-1507.
4. Biberthaler P, Linsenmeier U, Pfeifer KJ, Kroetz M, Mussack T, et al. (2006) Serum S-100B concentration provides additional information for the indication of computed tomography in patients after minor head injury: a prospective multicenter study. Shock 25: 446-453.
5. Ruan S, Noyes K, Bazarian JJ (2009) The economic impact of S-100B as a prehead CT screening test on emergency department management of adult patients with mild traumatic brain injury. J Neurotrauma 26: 1655-1664.
6. Rothermundt M, Ponath G, Arolt V (2004) S100B in schizophrenic psychosis. Int Rev Neurobiol 59: 445-470.
7. Missler U, Wiesmann M, Friedrich C, Kaps M (1997) S-100 protein and neuron-specific enolase concentrations in blood as indicators of infarction volume and prognosis in acute ischemic stroke. Stroke 28: 1956-1960.
8. Griffin WS, Stanley LC, Ling C, White L, MacLeod V, et al. (1989) Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proc Natl Acad Sci U S A 86: 7611-7615.
9. Ingebrigtsen T, Waterloo K, Jacobsen EA, Langbakk B, Romner B (1999) Traumatic brain damage in minor head injury: relation of serum S-100 protein measurements to magnetic resonance imaging and neurobehavioral outcome. Neurosurgery 45: 468-475.
10. Biberthaler P, Mussack T, Wiedemann E, Kanz KG, Koelsch M, et al. (2001) Evaluation of S-100b as a specific marker for neuronal damage due to minor head trauma. World J Surg 25: 93-97.
11. Herrmann M, Curio N, Jost S, Wunderlich MT, Synowitz H, et al. (1999) Protein S-100B and neuron specific enolase as early neurobiochemical markers of the severity of traumatic brain injury. Restor Neurol Neurosci 14: 109-114.
12. Aurell A, Rosengren LE, Karlsson B, Olsson JE, Zbornikova V, et al. (1991) Determination of S-100 and glial fibrillary acidic protein concentrations in cerebrospinal fluid after brain infarction. Stroke 22: 1254-1258.
13. Goncalves CA, Leite MC, Nardin P (2008) Biological and methodological features of the measurement of S100B, a putative marker of brain injury. Clin Biochem 41: 755-763.
14. Fazio V, Bhudia SK, Marchi N, Aumayr B, Janigro D (2004) Peripheral detection of S100beta during cardiothoracic surgery: what are we really measuring? Ann Thorac Surg 78: 46-52.
15. Otto M, Holthusen S, Bahn E, Sohnchen N, Wiltfang J, et al. (2000) Boxing and running lead to a rise in serum levels of S-100B protein. Int J Sports Med 21: 551-555.
16. Stalnacke BM, Tegner Y, Sojka P (2003) Playing ice hockey and basketball increases serum levels of S-100B in elite players: a pilot study. Clin J Sport Med 13: 292-302.
17. Hasselblatt M, Mooren FC, von Ahsen N, Keyvani K, Fromme A, et al. (2004) Serum S100beta increases in marathon runners reflect extracranial release rather than glial damage. Neurology 62: 1634-1636.
18. Marchi N, Angelov L, Masaryk T, Fazio V, Granata T, et al. (2007) Seizurepromoting effect of blood-brain barrier disruption. Epilepsia 48: 732-742.
19. Anderson RE, Hansson LO, Nilsson O, Liska J, Settergren G, et al. (2001) Increase in serum S100A1-B and S100BB during cardiac surgery arises from extracerebral sources. Ann Thorac Surg 71: 1512-1517.
20. Steiner J, Schiltz K, Walter M, Wunderlich MT, Keilhoff G, et al. (2010) S100B serum levels are closely correlated with body mass index: an important caveat in neuropsychiatric research. Psychoneuroendocrinology 35: 321-324.
21. Donato R (2001) S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int J Biochem Cell Biol 33: 637-668.
22. Marchi N, Cavaglia M, Bhudia S, Hallene K, Janigro D (2004) Peripheral markers of blood-brain barrier damage. Clinica Chimica Acta 342: 1-12.
23. Marchi N, Fazio V, Cucullo L, Kight K, Masaryk TJ, et al. (2003) Serum transthyretin as a possible marker of blood-to-CSF barrier disruption. Journal of Neuroscience 23: 1949-1955.
24. Vogelbaum MA, Masaryk T, Mazzone P, Mekhail T, Fazio V, et al. (2005) S100beta as a predictor of brain metastases: brain versus cerebrovascular damage. Cancer 104: 817-824.
25. Abdul-Khaliq H, Schubert S, Stoltenburg-Didinger G, Troitzsch D, Bottcher W, et al. (2000) Protein S-100beta in brain and serum after deep hypothermic circulatory arrest in rabbits: relationship to perivascular astrocytic swelling. Clin Chem Lab Med 38: 1169-1172.
26. Abdul-Khaliq H, Schubert S, Fischer T, Bottcher W, Harke C, et al. (2000) The effect of continuous treatment with sodium nitroprusside on the serum kinetics of the brain marker protein S-100beta in neonates undergoing corrective cardiac surgery by means of hypothermic cardiopulmonary bypass. Clin Chem Lab Med 38: 1173-1175.
27. Biberthaler P, Mussack T, Wiedemann E, Kanz KG, Gilg T, et al. (2000) Influence of alcohol exposure on S-100b serum levels. Acta Neurochir Suppl 76: 177-179.
28. Foerch C, Wunderlich MT, Dvorak F, Humpich M, Kahles T, et al. (2007) Elevated serum S100B levels indicate a higher risk of hemorrhagic transformation after thrombolytic therapy in acute stroke. Stroke 38: 2491-2495.
29. Raabe A, Menon DK, Gupta S, Czosnyka M, Pickard JD (1998) Jugular venous and arterial concentrations of serum S-100B protein in patients with severe head injury: a pilot study. J Neurol Neurosurg Psychiatry 65: 930-932.
30. Watson P, Shirreffs SM, Maughan RJ (2005) Blood-brain barrier integrity may be threatened by exercise in a warm environment. Am J Physiol Regul Integr Comp Physiol 288: R1689-R1694.
31. Pelinka LE, Harada N, Szalay L, Jafarmadar M, Redl H, et al. (2004) Release of S100B differs during ischemia and reperfusion of the liver, the gut, and the kidney in rats. Shock 21: 72-76.
32. Savola O, Pyhtinen J, Leino TK, Siitonen S, Niemela O, et al. (2004) Effects of head and extracranial injuries on serum protein S100B levels in trauma patients. J Trauma 56: 1229-1234.
33. Korfias S, Stranjalis G, Papadimitriou A, Psachoulia C, Daskalakis G, et al. (2006) Serum S-100B protein as a biochemical marker of brain injury: a review of current concepts. Curr Med Chem 13: 3719-3731.
34. Dassan P, Keir G, Brown MM (2009) Criteria for a clinically informative serum biomarker in acute ischaemic stroke: a review of S100B. Cerebrovasc Dis 27: 295-302.
35. Geyer C, Ulrich A, Grafe G, Stach B, Till H (2009) Diagnostic value of S100B and neuron-specific enolase in mild pediatric traumatic brain injury. J Neurosurg Pediatr 4: 339-344.
36. Nylen K, Ost M, Csajbok LZ, Nilsson I, Hall C, et al. (2008) Serum levels of S100B, S100A1B and S100BB are all related to outcome after severe traumatic brain injury. Acta Neurochir (Wien) 150: 221-227.
37. Biberthaler P, Mussack T, Wiedemann E, Kanz KG, Mutschler W, et al. (2002) Rapid identification of high-risk patients after minor head trauma (MHT) by assessment of S-100B: ascertainment of a cut-off level. Eur J Med Res 7: 164-170.
38. Biberthaler P, Mussack T, Wiedemann E, Gilg T, Soyka M, et al. (2001) Elevated serum levels of S-100B reflect the extent of brain injury in alcohol intoxicated patients after mild head trauma. Shock 16: 97-101.
39. Mussack T, Biberthaler P, Kanz KG, Wiedemann E, Gippner-Steppert C, et al. (2002) Serum S-100B and interleukin-8 as predictive markers for comparative neurologic outcome analysis of patients after cardiac arrest and severe traumatic brain injury. Crit Care Med 30: 2669-2674.
40. Mussack T, Biberthaler P, Wiedemann E, Kanz KG, Englert A, et al. (2000) S-100b as a screening marker of the severity of minor head trauma (MHT)-a pilot study. Acta Neurochir Suppl 76: 393-396.
41. Baudier J, Gerard D (1986) Ions binding to S100 proteins. II. Conformational studies and calcium-induced conformational changes in S100 alpha alpha protein: the effect of acidic pH and calcium incubation on subunit exchange in S100a (alpha beta) protein. J Biol Chem 261: 8204-8212.
42. Mann M (2008) Can proteomics retire the western blot? J Proteome Res 7: 3065.
43. Pineau JC, Guihard-Costa AM, Bocquet M (2007) Validation of ultrasound techniques applied to body fat measurement. A comparison between ultrasound techniques, air displacement plethysmography and bioelectrical impedance vs. dual-energy X-ray absorptiometry. Ann Nutr Metab 51: 421-427.
44. Anderson RE, Hansson LO, Nilsson O, Dijlai-Merzoug R, Settergren G (2001) High serum S100B levels for trauma patients without head injuries. Neurosurgery 48: 1255-1258
45. Jonsson H, Johnsson P, Hoglund P, Alling C, Blomquist S (2000) Elimination of S100B and renal function after cardiac surgery. J Cardiothorac Vasc Anesth 14: 698-701.
46. Raabe A, Kopetsch O, Woszczyk A, Lang J, Gerlach R, et al. (2003) Serum S-100B protein as a molecular marker in severe traumatic brain injury. Restor Neurol Neurosci 21: 159-169.
47. Portela LV, Tort AB, Schaf DV, Ribeiro L, Nora DB, et al. (2002) The serum S100B concentration is age dependent. Clin Chem 48: 950-952.
48. Mazzone PJ, Marchi N, Fazio V, Taylor JM, Masaryk T, et al. (2009) Small vessel ischemic disease of the brain and brain metastases in lung cancer patients. PLoS One 4: e7242.