DNA alterations of microsatellite DNA, p53, APC and K-ras in Chinese colorectal cancer patients

European Journal of Clinical Investigation

Volumn 42, Issue 7, 2012, Pages 751-759

  Xu, Xin Min ^a,b,c   Qian, Jian Chang ^c,d   Cai, Zhe ^e   Tang, Tao ^e   Wang, Peng ^e   Zhang, Ke Hua ^d   Deng, Zhou Lu ^e   Cai, Jian Ping ^c  

^a GRADUATE SCHOOL OF PEKING UNION MEDICAL COLLEGE   (China)

^b BEIJING HOSPITAL   (China)

^c BEIJING HOSPITAL   (China)

^d WENZHOU MEDICAL UNIVERSITY   (China)

^e CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

Author keywords

APC; Colorectal cancer; K ras; Microsatellite DNA; P53

Indexed keywords

MICROSATELLITE DNA;

ADENOMATOUS POLYPOSIS COLI GENE; ADULT; AGED; ARTICLE; CANCER STAGING; CAPILLARY ELECTROPHORESIS; CHINESE; CODON; COLORECTAL CANCER; CORRELATION ANALYSIS; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DNA MODIFICATION; FEMALE; GENE; GENE SEQUENCE; GENETIC SCREENING; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; LIVER METASTASIS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MOLECULAR CLONING; MOLECULAR DIAGNOSIS; MUTATIONAL ANALYSIS; ONCOGENE K RAS; P53 GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; COLORECTAL NEOPLASMS; DNA, NEOPLASM; ELECTROPHORESIS, CAPILLARY; FEMALE; FLUORESCENCE; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS P21(RAS); TUMOR SUPPRESSOR PROTEIN P53;

EID: 84862783000     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2011.02641.x     Document Type: Article

References (33)

1. Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin 2010;60:277-300.
2. Zheng S. Recent study on colorectal cancer in China: early detection and novel related gene. Chin Med J 1997;110:309-10.
3. Markowitz SD, Bertagnolli MM. Molecular origins of cancer: molecular basis of colorectal cancer. N Engl J Med 2009;361:2449-60.
4. Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87:159-70.
5. Kinzler KW, Vogelstein B. Colorectal tumors. In: Vogelstein B, Kinzler KW, editor. The Genetic Basis of Human Cancer, 2nd edn. New York: McGraw-Hill, 2002:583-612.
6. Loukola A, Eklin K, Laiho P, Salovaara R, Kristo P, Jarvinen H et al. Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC). Cancer Res 2001;61:4545-9.
7. Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW et al. A national cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58:5248-57.
8. Yamada K, Kanazawa S, Koike J, Sugiyama H, Xu C, Funahashi K et al. Microsatellite instability at tetranucleotide repeats in sporadic colorectal cancer in Japan. Oncol Rep 2010;23:551-61.
9. Berney CR, Fisher RJ, Yang J, Russell PJ, Crowe PJ. Genomic alterations (LOH, MI) on chromosome 17q21-23 and prognosis of sporadic colorectal cancer. Int J Cancer 2000;89:1-7.
10. Arzimanoglou II, Gilbert F, Barber HR. Microsatellite instability in human solid tumors. Cancer 1998;82:1808-20.
11. Chang SC, Lin JK, Lin TC, Liang WY. Loss of heterozygosity: an independent prognostic factor of colorectal cancer. World J Gastroenterol 2005;11:778-84.
12. Lin JK, Chang SC, Yang YC, Li AF. Loss of heterozygosity and DNA aneuploidy in colorectal adenocarcinoma. Ann Surg Oncol 2003;10:1086-94.
13. Conlin A, Smith G, Carey FA, Wolf CR, Steele RJ. The prognostic significance of K-ras, p53, and APC mutations in colorectal carcinoma. Gut 2005;54:1283-6.
14. Oving IM, Clevers HC. Molecular causes of colon cancer. Eur J Clin Invest 2002;32:448-57.
15. Nagase H, Nakamura Y. Mutations of the APC (adenomatous polyposis coli) gene. Hum Mutat 1993;2:425-34.
16. Smith G, Carey FA, Beattie J, Wilkie MJ, Lightfoot TJ, Coxhead J et al. Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer. Proc Natl Acad Sci USA 2002;99:9433-8.
17. Friday BB, Adjei AA. K-ras as a target for cancer therapy. Biochim Biophys Acta 2005;1756:127-44.
18. Brink M, de Goeij AF, Weijenberg MP, Roemen GM, Lentjes MH, Pachen MM et al. K-ras oncogene mutations in sporadic colorectal cancer in The Netherlands cohort study. Carcinogenesis 2003;24:703-10.
19. Edkins S, O'Meara S, Parker A, Stevens C, Reis M, Jones S et al. Recurrent KRAS Codon 146 mutations in human colorectal cancer. Cancer Biol Ther 2006;5:928-32.
20. Chang YS, Yeh KT, Chang TJ, Chai C, Lu HC, Hsu NC et al. Fast simultaneous detection of K-RAS mutations in colorectal cancer. BMC Cancer 2009;9:179-85.
21. Yu B, Sawyer NA, Chiu C, Oefner PJ, Underhill PA. DNA mutation detection using denaturing high-performance liquid chromatography (DHPLC). Curr Protoc Hum Genet 2006;Chapter 7.10.1-7.10.12.
22. Mahdavinia M, Bishehsari F, Verginelli F, Cumashi A, Lattanzio R, Sotoudeh M et al. P53 mutations in colorectal cancer from northern Iran: relationships with site of tumor origin, microsatellite instability and K-ras mutations. J Cell Physiol 2008;216:543-50.
23. Jeon CH, Lee HI, Shin IH, Park JW. Genetic alterations of APC, K-ras, p53, MSI, and MAGE in Korean colorectal cancer patients. Int J Colorectal Dis 2008;23:29-35.
24. Huang YQ, Yuan Y, Ge WT, Hu HG, Zhang SZ, Zheng S. Comparative features of colorectal and gastric cancers with microsatellite instability in Chinese patients. J Zhejiang Univ Sci B 2010;11:647-53.
25. Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993;260:816-9.
26. Nagahashi M, Ajioka Y, Lang I, Szentirmay Z, Kasler M, Nakadaira H et al. Genetic changes of p53, K-ras, and microsatellite instability in gallbladder carcinoma in high-incidence areas of Japan and Hungary. World J Gastroenterol 2008;14:70-5.
27. Samowitz WS, Holden JA, Curtin K, Edwards SL, Walker AR, Lin HA et al. Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer. Am J Pathol 2001;158:1517-24.
28. Calistri D, Rengucci C, Seymour I, Lattuneddu A, Polifemo AM, Monti F et al. Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression. J Cell Physiol 2005;204:484-8.
29. Yunxia Z, Jun C, Guanshan Z, Yachao L, Xueke Z, Jin L. Mutations in epidermal growth factor receptor and K-ras in Chinese patients with colorectal cancer. BMC Med Genet 2010;11:34.
30. Takashima H, Boerkoel CF, Lupski JR. Screening for mutations in a genetically heterogeneous disorder: DHPLC versus DNA sequence for mutation detection in multiple genes causing Charcot-Marie-Tooth neuropathy. Genet Med 2001;3:335-42.
31. Ishimura N, Yamasawa K, Karim Rumi MA, Kadowaki Y, Ishihara S, Amano Y et al. BRAF and K-ras gene mutations in human pancreatic cancers. Cancer Lett 2003;199:169-73.
32. Scott FM, Modali R, Lehman TA, Seddon M, Kelly K, Dempsey EC et al. High frequency of K-ras codon 12 mutations in bronchoalveolar lavage fluid of patients at high risk for second primary lung cancer. Clin Cancer Res 1997;3:479-82.
33. Algaba F, Trias I, Santinelli A, Montironi R. TP53 in urologic tumors. Anal Quant Cytol Histol 2003;25:123-30.