Genetic alterations of APC, K-ras, p53, MSI, and MAGE in Korean colorectal cancer patients

International Journal of Colorectal Disease

Volumn 23, Issue 1, 2008, Pages 29-35

  Jeon, Chang Ho ^a   Lee, Han Il ^a   Shin, Im Hee ^a   Park, Jong Wook ^b  

^a Catholic University of Daegu   (South Korea)

^b Keimyung University   (South Korea)

Author keywords

APC; Colorectal neoplasm; K ras; MAGE; p53

Indexed keywords

APC PROTEIN; K RAS PROTEIN; MELANOMA ANTIGEN; PROTEIN P53;

ADULT; AGED; ARTICLE; CANCER PATIENT; CANCER TISSUE; CARCINOGENESIS; CAUCASIAN; CODON; COLORECTAL CANCER; CONTROLLED STUDY; EARLY CANCER; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC MARKER; HUMAN; HUMAN TISSUE; KOREA; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MULTIPLE CANCER; PRIORITY JOURNAL; RACE DIFFERENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGED; ANTIGENS, NEOPLASM; ASIAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, APC; GENES, RAS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KOREA; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 36348972904     PISSN: 01791958     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00384-007-0373-0     Document Type: Article

References (33)

1. Goh KL, Quek KF, Yeo GTS, Hilmi IN, Lee CK, Hasnida N, Aznan M, Kwan KL, Ong KT (2005) Colorectal cancer in Asians: A demographic and anatomic survey in Malaysian patients undergoing colonoscopy. Aliment Pharmacol Ther 22:859-864
2. Kim DH, Ahn YO (2004) Molecular epidemiology of colon cancer. Cancer Res Treat 36:93-99
3. Kim JP, Park IS, Ahn YO, Shin MH, Ahn DH, Kang TW, Ko UR, Ku PS, Kim KY, Kim KH, Kim NK, Kim DJ, Kim DH, Kim BS, Kim SH, Park CT, Min JS, Park TK, Woo BH, Yoo H, Lee SW, Lee SJ, Cho KS, Joo HZ, Ham EK (1995) 1991 Cancer incidence in Seoul, Korea: Results of the implementation study of the Seoul cancer registry. J Korean Med Sci 10:74-84
4. Kim DH, Shin MH, Ahn YO (2000) Incidence pattern of colorectal cancer in Korea by subsite origin. J Korean Med Sci 15:675-681
5. Suh CI, Suh KA, Park SH, Chang HJ, Ko JW, Ahn DH (2000) Annual report of the central cancer registry in Korea-1998. J Korean Cancer Assoc 32:827-834
6. Shin HR, Jung KW, Won YJ, Park JG (2004) 2002 Annual report of the Korea central cancer registry: Based on registered data from 139 hospitals. Cancer Res Treat 36:93-99
7. Vogelstein B, Kinzler KW (2002) The genetic basis human cancer. In: Kinzler KW, Vogelstin B (eds) Colorectal cancers. McGraw-Hill, New York, pp 587-593
8. Smith G, Carey FA, Beattie J, Wilkie MJ, Lightfoot TJ, Coxhead J, Garner RC, Steele RJ, Wolf CR (2002) Mutations in APC, Kirsten-ras, and p53-alternative genetic pathways to colorectal cancer. PNAS 99:9433-9438
9. Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smits AM, Bos JL (1988) Genetic alterations during colorectal-tumor development. N Engl J Med 319:525-532
10. Jeong SY, Shin KH, Shin JH, Ku JL, Shin YK, Park SY, Kim WH, Park JG (2003) Microsatellite instability and mutations in DNA mismatch repair genes in sporadic colorectal cancers. Dis Colon Rectum 46:1069-1077
11. Bruggen P, Traversari C, Chomez P, Lurquin C, Plaen E, Eynde B, Knuth A, Boon T (1991) A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 13:1643-1647
12. Plaen E, Arden K, Traversari C, Gaforio JJ, Szikora JP, Smet C, Brasseur F, Bruggen P, Lethe B, Lurquin C, Brasseur R, Chomez P, Backer O, Cavenee W, Boon T (1994) Structure, chromosomal localization, and expression of 12 genes of the MAGE family. Immunogenetics 40:360-369
13. Park MS, Park JW, Jeon CH, Lee KD, Chang HK (2002) Expression of melanoma antigen-encoding genes (MAGE) by common primers for MAGE-A1 to A6 in colorectal carcinomas among Koreans. J Korean Med Sci 17:497-501
14. Kim KH, Choi JS, Kim IJ, Ku JL, Park JG (2006) Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues. World J Gastroenterol 21:5651-5657
15. Fearnhead NS, Wilding JL, Bodmer WF (2002) Genetics of colorectal cancer: Hereditary aspects and overview of colorectal tumorigenesis. Br Med Bull 64:27-43
16. Giehl K (2005) Oncogenic Ras in tumour progression and metastasis. Biol Chem 386:193-205
17. Vogelstein B, Kinzler KW (1992) p53 function and dysfunction. Cell 70:523-526
18. Park JW, Kwon TK, Kim IH, Sohn SS, Kim YS, Kim CI, Bae OS, Lee KS, Lee KD, Lee CS, Chang HK, Choe BK, Ahn YS, Jeon CH (2002) A new strategy for the diagnosis of MAGE-expressing cancers. J Immunol Methods 266:79-86
19. Dietmaier W, Hofstadter F (2001) Detection of microsatellite instability by real time PCR and hybridization probe melting point analysis. Lab Invest 81:1453-1456
20. Won YJ, Park KJ, Kwon HJ, Lee JH, Kim JH, Kim YJ, Chun SH, Han HJ, Park JG (1999) Germline mutations of the APC gene in Korean familial adenomatous polyposis patients. J Hum Genet 44:103-108
21. Hutter P, Rey-Berthod C, Chappuis PO (2001) Molecular and clinical characteristics in 32 families affected with familial adenomatous polyposis. Human Mutat 18:550
22. Gavert N, Yaron Y, Maiman T, Bercovich D, Rozen P, Shomrat R, Legum C Orr-Urtreger A (2002) Molecular analysis of the APC gene in 71 Israeli families: 17 novel mutations. Human Mutat 19:664
23. Luijt RB, Khan PM, Vasen HFA, Tops CMJ, Leeuwen-Cornelisse ISJ, Wijnen JT, Klift HM, Plug RJ, Griffioen G, Fodde G (1997) Molecular analysis of the APC gene in 105 Dutch kindreds with familial adenomatous polyposis: 67 germline mutations identified by DGGE, PTT, and southern Analysis. Human Mutat 9:7-16
24. Calistri D, Rengucci C, Seymour I, Lattuneddu A, Polifemo A, Monti F, Saragoni L, Amadori D (2005) Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression. J Cell Physiol 204:484-488
25. Oh HE, Cho SJ, Won NH, Lee D, Kim I, Yeom BW (2001) K-ras gene mutations and expression of K-ras, p16, cyclin D1 and p53 in synchronous lesions of the colon adenoma carcinoma sequences. Korean J Pathol 35:291-298
26. Oliver M, Eeles R, Hollstein M, Khan MA, Harris CC, Hainaut P (2002) The IARC TP53 database: New online mutation analysis and recommendations to users. Human Mutat 19:607-614
27. Hong SI, Hong WS, Jang JJ, Lee DS, Cho NS, Jung ME, Kim HB, Ha GW, Park IC, Cho DS (1994) Alterations of p53 gene in primary gastric cancer tissues. Anticancer Res 14:1251-1255
28. Alves PM, Levy N, Bouzourene H, Viatte S, Bricard G, Ayyoub M, Vuilleumier H, Givel JC, Halkic N, Speiser DE, Romero P, Levy F (2007) Molecular and immunological evaluation of the expression of cancer/ testis gene products in human colorectal cancer. Cancer Immunol Immunother 56:839-847
29. Koketsu S, Watanabe T, Kazama S, Ishihara S, Komuro Y, Nagawa H (2004) What types of colorectal cancer overexpress the MAGE protein? Hepatogastroenterology 51:1648-1652
30. Fodde R (2002) The APC gene in colorectal cancer. Eur J Cancer 38:867-871
31. Muta H, Noguchi M, Perucho M, Ushio K, Sugihara K, Ochiai A, Nawata J, Hirohashi S (1996) Clinical implications of microsatellite instability in colorectal cancers. Cancer 77:265-270
32. Ruschoff J, Bocker T, Schlegel J, Stumm G, Hofstaedter F (1995) Microsatellite instability: New aspects in the carcinogenesis of colorectal carcinoma. Virchows Arch 426:215-222
33. Cravo ML, Fidalgo PO, Lage PA, Albuquerque CM, Chaves PP, Claro I, Gomes T, Gaspar C, Soares JO, Nobre-Leitao C (1999) Validation and simplification of Bethesda guidelines for identifying apparently sporadic forms of colorectal carcinoma with microsatellite instability. Cancer 85:779-785