Contributions of dynamic venous blood volume versus oxygenation level changes to BOLD fMRI

NeuroImage

Volumn 60, Issue 4, 2012, Pages 2238-2246

  Zong, Xiaopeng ^a   Kim, Tae ^a   Kim, Seong Gi ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

BOLD; BOLD undershoot; CBV; Cerebral arterial blood volume; Cerebral venous blood volume; Venous oxygenation level

Indexed keywords

CHLORALOSE; DEOXYHEMOGLOBIN; IRON OXIDE; NANOPARTICLE;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; BLOOD OXYGENATION; BOLD SIGNAL; BRAIN BLOOD FLOW; CONTROLLED STUDY; FOREFOOT; FUNCTIONAL MAGNETIC RESONANCE IMAGING; MAGNETIC FIELD; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; SOMATOSENSORY CORTEX; SOMATOSENSORY STIMULATION;

ANIMALS; BLOOD VOLUME; BRAIN; CEREBROVASCULAR CIRCULATION; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84862779347     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2012.02.052     Document Type: Article

References (56)

1. Adam J.-F., Elleaume H., le Duc G., Corde S., Charvet A.-M., Tropres I., le Bas J.-F., Esteve F. Absolute cerebral blood volume and blood flow measurements based on synchrotron radiation quantitative computed tomography. J. Cereb. Blood Flow Metab. 2003, 23:499-512.
2. Ances B.M., Greenberg J.H., Detre J.A. The effects of graded hypercapnia on the activation flow coupling response due to forepaw stimulation in alpha-chloralose anesthetized rats. Brain Res. 2001, 911:82-88.
3. Bakalova R., Matsuura T., Kanno I. Frequency dependence of local cerebral blood flow induced by somatosensory hind paw stimulation in rat under normo- and hypercapnia. Jpn. J. Physiol. 2001, 51:201-208.
4. Bandettini P.A., Jesmanowicz A., Wong E.C., Hyde J.S. Processing strategies for time-course data sets in functional MRI of the human brain. Magn. Reson. Med. 1993, 30:161-173.
5. *-, phase-, and susceptibility-weighted contrast. Magn. Reson. Med. 2011, 65:544-550.
6. Buxton R.B., Wong E.C., Frank L.R. Dynamics of blood flow and oxygenation changes during brain activation: the balloon model. Magn. Reson. Med. 1998, 39:855-864.
7. Chen J.J., Pike G.B. Origins of the BOLD post-stimulus undershoot. Neuroimage 2009, 46:559-568.
8. * determination in the presence of flow. Magn. Reson. Med. 1994, 32:540-545.
9. Cohen E.R., Ugurbil K., Kim S.G. Effect of basal conditions on the magnitude and dynamics of the blood oxygenation level-dependent fMRI response. J. Cereb. Blood Flow Metab. 2002, 22:1042-1053.
10. Cox R.W. AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput. Biomed. Res. 1996, 29:162-173.
11. Davis T.L., Kwong K.K., Weisskoff R.M., Rosen B.R. Calibrated functional MRI: mapping the dynamics of oxidative metabolism. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:1834-1839.
12. Drew P.J., Shih A.Y., Kleinfeld D. Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:8473-8478.
13. Farber N.E., Harkin C.P., Niedfeldt J., Hudetz A.G., Kampine J.P., Schmeling W.T. Region-specific and agent-specific dilation of intracerebral microvessels by volatile anesthetics in rat brain slices. Anesthesiology 1997, 87:1191-1198.
14. Frahm J., Kruger G., Merboldt K.D., Kleinschmidt A. Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man. Magn. Reson. Med. 1996, 35:143-148.
15. Gati J.S., Menon R.S., Ugurbil K., Rutt B.K. Experimental determination of the BOLD field strength dependence in vessels and tissue. Magn. Reson. Med. 1997, 38:296-302.
16. Herscovitch P., Raichle M.E. What is the correct value for the brain-blood partition coefficient for water?. J. Cereb. Blood Flow Metab. 1985, 5:65-69.
17. Hoge R.D., Atkinson J., Gill B., Crelier G.R., Marrett S., Pike G.B. Stimulus-dependent BOLD and perfusion dynamics in human V1. Neuroimage 1999, 9:573-585.
18. Hyder F. Neuroimaging with calibrated fMRI. Stroke 2004, 35:2635-2641.
19. Kennan R.P., Scanley B.E., Innis R.B., Gore J.C. Physiological basis for BOLD MR signal changes due to neuronal stimulation: separation of blood volume and magnetic susceptibility effects. Magn. Reson. Med. 1998, 40:840-846.
20. Kerskens C.M., Hoehn-Berlage M., Schmitz B., Busch E., Bock C., Gyngell M.L., Hossmann K.A. Ultrafast perfusion-weighted MRI of functional brain activation in rats during forepaw stimulation: comparison with T2-weighted MRI. NMR Biomed. 1996, 9:20-23.
21. Kida I., Maciejewski P.K., Hyder F. Dynamic imaging of perfusion and oxygenation by functional magnetic resonance imaging. J. Cereb. Blood Flow Metab. 2004, 24:1369-1381.
22. Kim S.G., Rostrup E., Larsson H.B., Ogawa S., Paulson O.B. Determination of relative CMRO2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation. Magn. Reson. Med. 1999, 41:1152-1161.
23. Kim T., Hendrich K., Kim S.G. Functional MRI with magnetization transfer effects: determination of BOLD and arterial blood volume changes. Magn. Reson. Med. 2008, 60:1518-1523.
24. Kim T., Hendrich K.S., Masamoto K., Kim S.G. Arterial versus total blood volume changes during neural activity-induced cerebral blood flow change: implication for BOLD fMRI. J. Cereb. Blood Flow Metab. 2007, 27:1235-1247.
25. Kim T., Kim S.-G. Temporal dynamics and spatial specificity of arterial and venous blood volume changes during visual stimulation: implication for BOLD quantification. J. Cereb. Blood Flow Metab. 2011, 31:1211-1222.
26. Kim T., Kim S.G. Quantification of cerebral arterial blood volume and cerebral blood flow using mri with modulation of tissue and vessel (MOTIVE) signals. Magn. Reson. Med. 2005, 54:333-342.
27. Kim T., Kim S.G. Quantification of cerebral arterial blood volume using arterial spin labeling with intravoxel incoherent motion-sensitive gradients. Magn. Reson. Med. 2006, 55:1047-1057.
28. Kim T., Kim S.G. Cortical layer-dependent arterial blood volume changes: improved spatial specificity relative to BOLD fMRI. Neuroimage 2010, 49:1340-1349.
29. Lee S.P., Duong T.Q., Yang G., Iadecola C., Kim S.G. Relative changes of cerebral arterial and venous blood volumes during increased cerebral blood flow: implications for BOLD fMRI. Magn. Reson. Med. 2001, 45:791-800.
30. Lee S.P., Silva A.C., Kim S.G. Comparison of diffusion-weighted high-resolution CBF and spin-echo BOLD fMRI at 9.4T. Magn. Reson. Med. 2002, 47:736-741.
31. Lee S.P., Silva A.C., Ugurbil K., Kim S.G. Diffusion-weighted spin-echo fMRI at 9.4T: microvascular/tissue contribution to BOLD signal changes. Magn. Reson. Med. 1999, 42:919-928.
32. Leite F.P., Tsao D., Vanduffel W., Fize D., Sasaki Y., Wald L.L., Dale A.M., Kwong K.K., Orban G.A., Rosen B.R., Tootell R.B., Mandeville J.B. Repeated fMRI using iron oxide contrast agent in awake, behaving macaques at 3Tesla. Neuroimage 2002, 16:283-294.
33. * estimation. Magn. Reson. Med. 1998, 39:685-690.
34. Lin W., Paczynski R.P., Kuppusamy K., Hsu C.Y., Haacke E.M. Quantitative measurements of regional cerebral blood volume using MRI in rats: effects of arterial carbon dioxide tension and mannitol. Magn. Reson. Med. 1997, 38:420-428.
35. Lu H., Soltysik D.A., Ward B.D., Hyde J.S. Temporal evolution of the CBV-fMRI signal to rat whisker stimulation of variable duration and intensity: a linearity analysis. Neuroimage 2005, 26:432-440.
36. Mandeville J.B., Marota J.J., Kosofsky B.E., Keltner J.R., Weissleder R., Rosen B.R., Weisskoff R.M. Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn. Reson. Med. 1998, 39:615-624.
37. Mandeville J.B., Marota J.J.A., Ayata C., Zaharchuk G., Moskowitz M.A., Rosen B., Weisskoff R. Evidence of a cerebrovascular postarteriole windkessel with delayed compliance. J. Cereb. Blood Flow Metab. 1999, 19:679-689.
38. Masamoto K., Kim T., Fukuda M., Wang P., Kim S.G. Relationship between neural, vascular, and BOLD signals in isoflurane-anesthetized rat somatosensory cortex. Cereb. Cortex 2007, 17:942-950.
39. 2 measurement with arterial spin labeling at 9.4Tesla. Proc. Intl. Soc. Mag. Reson. Med. 2011, 19:372.
40. Miller K.L., Luh W.M., Liu T.T., Martinez A., Obata T., Wong E.C., Frank L.R., Buxton R.B. Nonlinear temporal dynamics of the cerebral blood flow response. Hum. Brain Mapp. 2001, 13:1-12.
41. Obata T., Liu T.T., Miller K.L., Luh W.M., Wong E.C., Frank L.R., Buxton R.B. Discrepancies between BOLD and flow dynamics in primary and supplementary motor areas: application of the balloon model to the interpretation of BOLD transients. Neuroimage 2004, 21:144-153.
42. Orrison W., Lewine J., Ja S., Hartshorne M.F. Functional Magnetic Resonance Imaging. Functional Brain Imaging 1995, Mosby, St. Louis.
43. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates 1986, Academic Press, San Diego.
44. * measurements in human brain at 1.5, 3 and 7T. Magn. Reson. Imaging 2007, 25:748-753.
45. Scheffler K., Seifritz E., Haselhorst R., Bilecen D. Titration of the BOLD effect: separation and quantitation of blood volume and oxygenation changes in the human cerebral cortex during neuronal activation and ferumoxide infusion. Magn. Reson. Med. 1999, 42:829-836.
46. Schwarzbauer C., Morrissey S.P., Deichmann R., Hillenbrand C., Syha J., Adolf H., Nöth U., Haase A. Quantitative magnetic resonance imaging of capillary water permeability and regional blood volume with an intravascular MR contrast agent. Magn. Reson. Med. 1997, 37:769-777.
47. Sicard K., Shen Q., Brevard M.E., Sullivan R., Ferris C.F., King J.A., Duong T.Q. Regional cerebral blood flow and BOLD responses in conscious and anesthetized rats under basal and hypercapnic conditions: implications for functional MRI studies. J. Cereb. Blood Flow Metab. 2003, 23:472-481.
48. Silva A.C., Koretsky A.P., Duyn J.H. Functional MRI impulse response for BOLD and CBV contrast in rat somatosensory cortex. Magn. Reson. Med. 2007, 57:1110-1118.
49. Silva A.C., Lee S.P., Yang G., Iadecola C., Kim S.G. Simultaneous blood oxygenation level-dependent and cerebral blood flow functional magnetic resonance imaging during forepaw stimulation in the rat. J. Cereb. Blood Flow Metab. 1999, 19:871-879.
50. * on oxygen saturation at 1.5 and 4.7Tesla. Magn. Reson. Med. 2003, 49:47-60.
51. *(2), and non-Lorentzian signal behavior. Magn. Reson. Med. 2001, 45:533-542.
52. Thulborn K.R., Waterton J.C., Matthews P.M., Radda G.K. Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochim. Biophys. Acta 1982, 714:265-270.
53. Tropres I., Grimault S., Vaeth A., Grillon E., Julien C., Payen J.F., Lamalle L., Decorps M. Vessel size imaging. Magn. Reson. Med. 2001, 45:397-408.
54. Tsekos N.V., Zhang F., Merkle H., Nagayama M., Iadecola C., Kim S.G. Quantitative measurements of cerebral blood flow in rats using the FAIR technique: correlation with previous iodoantipyrine autoradiographic studies. Magn. Reson. Med. 1998, 39:564-573.
55. Vazquez A.L., Fukuda M., Tasker M.L., Masamoto K., Kim S.G. Changes in cerebral arterial, tissue and venous oxygenation with evoked neural stimulation: implications for hemoglobin-based functional neuroimaging. J. Cereb. Blood Flow Metab. 2010, 30:428-439.
56. Wegener S., Wong E.C. Longitudinal MRI studies in the isoflurane-anesthetized rat: long-term effects of a short hypoxic episode on regulation of cerebral blood flow as assessed by pulsed arterial spin labelling. NMR Biomed. 2008, 21:696-703.