Synthesis of novel D-ring fused 7′-aryl-androstano[17,16-d][1,2,4] triazolo[1,5-a]pyrimidines

Steroids

Volumn 77, Issue 5, 2012, Pages 367-374

  Huang, Li Hua ^a   Zheng, Yong Fei ^a   Song, Chuan Jun ^a   Wang, Yan Guang ^a   Xie, Zhi Yu ^a   Lai, Yao Wen ^a   Lu, Yong Zheng ^a   Liu, Hong Min ^a  

^a ZHENGZHOU UNIVERSITY   (China)

Author keywords

1,2,4 Triazolo 1,5 a pyrimidine; 16 Arylidene 17 ketosteroids; 3 Amino 1,2,4 triazole; Heterosteroids; Steroidal 17,16 d triazolopyrimidines

Indexed keywords

3 OXO 4 AZA 7' (3 NITROPHENYL) 5ALPHA ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3 OXO 4 AZA 7' (3,4,5 TRIMETHOXYPHENYL) 5ALPHA ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3 OXO 4 AZA 7' (4 BROMOPHENYL) 5ALPHA ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3 OXO 4 AZA 7' (4 CHLOROPHENYL) 5ALPHA ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3 OXO 4 AZA 7' (4 DIMETHYLAMINOPHENYL) 5ALPHA ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3 OXO 4 AZA 7' (4 FLUOROPHENYL) 5ALPHA ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3 OXO 4 AZA 7' (4 ISOPROPYLPHENYL) 5ALPHA ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3 OXO 4 AZA 7' (4 METHOXYPHENYL) 5ALPHA ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3 OXO 4 AZA 7' (4 MORPHOLINYLPHENYL) 5ALPHA ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3 OXO 4 AZA 7' PHENYL 5ALPHA ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3BETA HYDROXY 5 EN 7' (4 CHLOROPHENYL)ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3BETA HYDROXY 5 EN 7' (4 DIMETHYLAMINOPHENYL)ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3BETA HYDROXY 5 EN 7' (4 ISOPROPYLPHENYLPHENYL)ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3BETA HYDROXY 5 EN 7' (4 METHOXYPHENYL)ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3BETA HYDROXY 5 EN 7' (4 METHYLSULFONYLPHENYL)ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3BETA HYDROXY 5 EN 7' (4 MORPHOLINYLPHENYL)ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3BETA HYDROXY 5 EN 7' (PHENOXYPHENYL)ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; 3BETA HYDROXY 5 EN 7' PHENYLANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE; ANDROSTANO[17,16 D][1,2,4]TRIAZOLO[1,5 A]PYRIMIDINE DERIVATIVE; HETEROCYCLIC COMPOUND; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ALDEHYDES; ANDROSTANOLS; DEHYDROEPIANDROSTERONE; HETEROCYCLIC COMPOUNDS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; PYRIMIDINES; STEROIDS; TRIAZOLES;

EID: 84862777530     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2011.12.012     Document Type: Article

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