Synthesis and biological activity of azasteroidal [3,2-c]- and [17,16-c]pyrazoles

European Journal of Medicinal Chemistry

Volumn 31, Issue 3, 1996, Pages 241-247

  Gupta, R ^a   Pathak, D ^a   Jindal, D P ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Antiinflammatory activity; Antineoplastic activity; Azasteroid; Carrageenan test; Pyrazole derivative

Indexed keywords

2' (4 FLUOROPHENYL) 17A AZA 4,5 OXIDO D HOMO 5 ANDROSTANO[17,16C]PYRAZOL 3 ONE; AZASTEROID; HYDROCORTISONE; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORAL DRUG ADMINISTRATION; RAT; TUMOR CELL; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0029963037     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/0223-5234(96)89140-9     Document Type: Article

References (23)

1. Hirschman R, Steinberg NG, Buchschacher P et al (1963) J Am Chem Soc 85, 120-122
2. Fried JH, Mrozik H, Arth GE et al (1963) JAm Chem Soc 85, 236-238
3. Hirschman R, Steinberg NG, Schoenewaldt EF, Paleveda WI, Tishler M (1964) J Med Chem 7, 352-355
4. Strachan RG, Steinberg NG, Tishler M, Hirschmann R (1964) J Med Chem 7, 355
5. Hirschmann R, Buchschacher P, Steinberg NG et al (1964) J Am Chem Soc 86, 1520-1528
6. Hannah J, Kelly K, Patchett AA, Steelman SL, Morgan ER (1975) J Med Chem 18, 168-172
7. Steelman SL, Morgan ER, Glitzer MS (1971) Steroids 18, 129-139
8. Simons Jr SS, Thompson EB, Johnson DF (1979) Biochim Biophys Res Commun 86, 793-800
9. Schane HP, Harding HR, Creange JE, Botton I, Castracane VD, Snyder BW (1984) Endocrinology 114, 1983-1989
10. Jindal DP, Pathak D (1991) Eur J Med Chem 26, 651-654
11. Verma AK, Gupta R, Yadav MR, Sharma N, Jindal DP (1994) Indian J Chem 34B, 215-220
12. Jindal DP, Gupta R, Abraham J (1994) Indian J Chem 33B, 499-501
13. Eastham JF, Teranishi R (1995) In: Organic Synthesis, Vol 35 (Adams R, ed), John Wiley and Sons Ine, New York, 39-42
14. Edward JT, Holder D, Lunn WH, Puskas (1961) Can J Chem 39, 599-600
15. Edward JT, Morand PF (1960) Can J Chem 38, 1316
16. Singh H, Paul D (1974) Indian J Chem 12, 1210-1211
17. Bolt CC ( 1938) Rec Trav Chim 57, 905-910
18. Ranju, Pathak D, Jindal DP (1994) Indian J Chem 33B, 269-271
19. Bowden K, Heilbron IM, Jones ERH, Weedon BCL (1946) J Chem Soc 39-45
20. Camerino B, Patelli B, Vercellone A (1956) J Am Chem Soc 78, 3540-3541
21. Verma AK, Jindal DP (1995) Eur J Med Chem 30, 339-341
22. Winter CA, Risley EA, Nuss GW (1960) Proc Soc Exp Bio Med 111, 544-547
23. Newbould BB (1963) Br J Pharmacol 21, 127-136