메뉴 건너뛰기




Volumn 91, Issue 4, 2012, Pages 621-634

Advances in imaging to support the development of novel therapies for multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM; IMMUNOMODULATING AGENT; N ACETYLASPARTIC ACID; PLACEBO; RADIOLIGAND; SODIUM 23;

EID: 84862777007     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2011.349     Document Type: Article
Times cited : (17)

References (75)
  • 1
    • 79952501096 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
    • Polman, C.H. et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann. Neurol. 69, 292-302 (2011).
    • (2011) Ann. Neurol. , vol.69 , pp. 292-302
    • Polman, C.H.1
  • 4
    • 45149104981 scopus 로고    scopus 로고
    • Multiple sclerosis risk after optic neuritis: Final optic neuritis treatment trial follow-up
    • Optic Neuritis Study Group
    • Optic Neuritis Study Group. Multiple sclerosis risk after optic neuritis: final optic neuritis treatment trial follow-up. Arch. Neurol. 65, 727-732 (2008).
    • (2008) Arch. Neurol. , vol.65 , pp. 727-732
  • 5
    • 78649996252 scopus 로고    scopus 로고
    • Brainstem lesions in clinically isolated syndromes
    • Tintore, M. et al. Brainstem lesions in clinically isolated syndromes. Neurology 75, 1933-1938 (2010).
    • (2010) Neurology , vol.75 , pp. 1933-1938
    • Tintore, M.1
  • 6
    • 62149133114 scopus 로고    scopus 로고
    • Early MRI in optic neuritis: The risk for disability
    • Swanton, J.K. et al. Early MRI in optic neuritis: the risk for disability. Neurology 72, 542-550 (2009).
    • (2009) Neurology , vol.72 , pp. 542-550
    • Swanton, J.K.1
  • 8
    • 0034104079 scopus 로고    scopus 로고
    • Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis
    • DOI 10.1002/1531-8249(200003)47:3<391::AID-ANA20>3.0.CO;2-J
    • Evangelou, N., Esiri, M.M., Smith, S., Palace, J. & Matthews, P.M. Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis. Ann. Neurol. 47, 391-395 (2000). (Pubitemid 30141854)
    • (2000) Annals of Neurology , vol.47 , Issue.3 , pp. 391-395
    • Evangelou, N.1    Esiri, M.M.2    Smith, S.3    Palace, J.4    Matthews, P.M.5
  • 9
    • 0342288638 scopus 로고    scopus 로고
    • Axonal changes in chronic demyelinated cervical spinal cord plaques
    • Lovas, G., Szilágyi, N., Majtényi, K., Palkovits, M. & Komoly, S. Axonal changes in chronic demyelinated cervical spinal cord plaques. Brain 123 (Pt 2), 308-317 (2000). (Pubitemid 30055154)
    • (2000) Brain , vol.123 , Issue.2 , pp. 308-317
    • Lovas, G.1    Szilagyi, N.2    Majtenyi, K.3    Palkovits, M.4    Komoly, S.5
  • 10
    • 8844222623 scopus 로고    scopus 로고
    • Interferon beta-1b in secondary progressive MS: Results from a 3-year controlled study
    • Panitch, H., Miller, A., Paty, D. & Weinshenker, B.; North American Study Group on Interferon beta-1b in Secondary Progressive MS. Interferon beta-1b in secondary progressive MS: results from a 3-year controlled study. Neurology 63, 1788-1795 (2004). (Pubitemid 39532370)
    • (2004) Neurology , vol.63 , Issue.10 , pp. 1788-1795
    • Panitch, H.1
  • 13
    • 0027503708 scopus 로고
    • Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis
    • DOI 10.1002/ana.410340507
    • Katz, D., Taubenberger, J.K., Cannella, B., McFarlin, D.E., Raine, C.S. & McFarland, H.F. Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis. Ann. Neurol. 34, 661-669 (1993). (Pubitemid 23333237)
    • (1993) Annals of Neurology , vol.34 , Issue.5 , pp. 661-669
    • Katz, D.1    Taubenberger, J.K.2    Cannella, B.3    McFarlin, D.E.4    Raine, C.S.5    McFarland, H.F.6
  • 15
    • 59249105170 scopus 로고    scopus 로고
    • Differential diagnosis of suspected multiple sclerosis: A consensus approach
    • Miller, D.H. et al. Differential diagnosis of suspected multiple sclerosis: a consensus approach. Mult. Scler. 14, 1157-1174 (2008).
    • (2008) Mult. Scler. , vol.14 , pp. 1157-1174
    • Miller, D.H.1
  • 17
    • 73749087636 scopus 로고    scopus 로고
    • Comparison of [(11)C]-®-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker
    • Kreisl, W.C. et al. Comparison of [(11)C]-®-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker. Neuroimage 49, 2924-2932 (2010).
    • (2010) Neuroimage , vol.49 , pp. 2924-2932
    • Kreisl, W.C.1
  • 18
    • 79851473610 scopus 로고    scopus 로고
    • Mixed-affinity binding in humans with 18-kDa translocator protein ligands
    • Owen, D.R. et al. Mixed-affinity binding in humans with 18-kDa translocator protein ligands. J. Nucl. Med. 52, 24-32 (2011).
    • (2011) J. Nucl. Med. , vol.52 , pp. 24-32
    • Owen, D.R.1
  • 21
    • 33644584352 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
    • Polman, C.H. et al. A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N. Engl. J. Med. 354, 899-910 (2006).
    • (2006) N. Engl. J. Med. , vol.354 , pp. 899-910
    • Polman, C.H.1
  • 23
    • 76149093586 scopus 로고    scopus 로고
    • A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis
    • Kappos, L. et al. A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis. N. Engl. J. Med. 362, 387-401 (2010).
    • (2010) N. Engl. J. Med. , vol.362 , pp. 387-401
    • Kappos, L.1
  • 24
    • 80053533877 scopus 로고    scopus 로고
    • Randomized trial of oral teriflunomide for relapsing multiple sclerosis
    • O'Connor, P. et al. Randomized trial of oral teriflunomide for relapsing multiple sclerosis. N. Engl. J. Med. 365, 1293-1303 (2011).
    • (2011) N. Engl. J. Med. , vol.365 , pp. 1293-1303
    • O'Connor, P.1
  • 25
    • 54949143968 scopus 로고    scopus 로고
    • Alemtuzumab vs. interferon beta-1a in early multiple sclerosis
    • CAMMS223 Trial Investigators et al.
    • CAMMS223 Trial Investigators et al. Alemtuzumab vs. interferon beta-1a in early multiple sclerosis. N. Engl. J. Med. 359, 1786-1801 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , pp. 1786-1801
  • 26
    • 54149116366 scopus 로고    scopus 로고
    • Efficacy and safety of oral fumarate in patients with relapsingremitting multiple sclerosis: A multicentre, randomised, double-blind, placebo-controlled phase IIb study
    • Kappos, L. et al. Efficacy and safety of oral fumarate in patients with relapsingremitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study. Lancet 372, 1463-1472 (2008).
    • (2008) Lancet , vol.372 , pp. 1463-1472
    • Kappos, L.1
  • 27
    • 65249154822 scopus 로고    scopus 로고
    • Magnetic resonance imaging as a potential surrogate for relapses in multiple sclerosis: A meta-analytic approach
    • Sormani, M.P., Bonzano, L., Roccatagliata, L., Cutter, G.R., Mancardi, G.L. & Bruzzi, P. Magnetic resonance imaging as a potential surrogate for relapses in multiple sclerosis: a meta-analytic approach. Ann. Neurol. 65, 268-275 (2009).
    • (2009) Ann. Neurol. , vol.65 , pp. 268-275
    • Sormani, M.P.1    Bonzano, L.2    Roccatagliata, L.3    Cutter, G.R.4    Mancardi, G.L.5    Bruzzi, P.6
  • 28
    • 77951750526 scopus 로고    scopus 로고
    • Long-interval T2-weighted subtraction magnetic resonance imaging: A powerful new outcome measure in multiple sclerosis trials
    • Moraal, B. et al. Long-interval T2-weighted subtraction magnetic resonance imaging: a powerful new outcome measure in multiple sclerosis trials. Ann. Neurol. 67, 667-675 (2010).
    • (2010) Ann. Neurol. , vol.67 , pp. 667-675
    • Moraal, B.1
  • 29
    • 77949279537 scopus 로고    scopus 로고
    • Natalizumab-associated progressive multifocal leukoencephalopathy in patients with multiple sclerosis: Lessons from 28 cases
    • Clifford, D.B. et al. Natalizumab-associated progressive multifocal leukoencephalopathy in patients with multiple sclerosis: lessons from 28 cases. Lancet Neurol. 9, 438-446 (2010).
    • (2010) Lancet Neurol. , vol.9 , pp. 438-446
    • Clifford, D.B.1
  • 30
    • 77956379569 scopus 로고    scopus 로고
    • A serial study of retinal changes following optic neuritis with sample size estimates for acute neuroprotection trials
    • Henderson, A.P. et al. A serial study of retinal changes following optic neuritis with sample size estimates for acute neuroprotection trials. Brain 133, 2592-2602 (2010).
    • (2010) Brain , vol.133 , pp. 2592-2602
    • Henderson, A.P.1
  • 31
    • 84255194787 scopus 로고    scopus 로고
    • Early factors associated with axonal loss after optic neuritis
    • Henderson, A.P. et al. Early factors associated with axonal loss after optic neuritis. Ann. Neurol. 70, 955-963 (2011).
    • (2011) Ann. Neurol. , vol.70 , pp. 955-963
    • Henderson, A.P.1
  • 32
    • 68349107070 scopus 로고    scopus 로고
    • Imaging outcomes for neuroprotection and repair in multiple sclerosis trials
    • Barkhof, F., Calabresi, P.A., Miller, D.H. & Reingold, S.C. Imaging outcomes for neuroprotection and repair in multiple sclerosis trials. Nat. Rev. Neurol. 5, 256-266 (2009).
    • (2009) Nat. Rev. Neurol. , vol.5 , pp. 256-266
    • Barkhof, F.1    Calabresi, P.A.2    Miller, D.H.3    Reingold, S.C.4
  • 33
    • 6944246720 scopus 로고    scopus 로고
    • Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: A randomised, double-blind, placebo-controlled trial
    • DOI 10.1016/S0140-6736(04)17271-1, PII S0140673604172711
    • Filippi, M. et al. Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial. Lancet 364, 1489-1496 (2004). (Pubitemid 39410414)
    • (2004) Lancet , vol.364 , Issue.9444 , pp. 1489-1496
    • Filippi, M.1    Rovaris, M.2    Inglese, M.3    Barkhof, F.4    Stefano, N.D.5    Smith, S.6    Comi, P.G.7
  • 34
    • 61849095259 scopus 로고    scopus 로고
    • Sample sizes for brain atrophy outcomes in trials for secondary progressive multiple sclerosis
    • Altmann, D.R. et al. Sample sizes for brain atrophy outcomes in trials for secondary progressive multiple sclerosis. Neurology 72, 595-601 (2009).
    • (2009) Neurology , vol.72 , pp. 595-601
    • Altmann, D.R.1
  • 35
    • 77953476309 scopus 로고    scopus 로고
    • Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: A randomised, double-blind, placebo-controlled, parallelgroup trial
    • Kapoor, R. et al. Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: a randomised, double-blind, placebo-controlled, parallelgroup trial. Lancet Neurol. 9, 681-688 (2010).
    • (2010) Lancet Neurol. , vol.9 , pp. 681-688
    • Kapoor, R.1
  • 36
    • 0033544320 scopus 로고    scopus 로고
    • Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS
    • Rudick, R.A., Fisher, E., Lee, J.C., Simon, J. & Jacobs, L. Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS. Multiple Sclerosis Collaborative Research Group. Neurology 53, 1698-1704 (1999). (Pubitemid 29530342)
    • (1999) Neurology , vol.53 , Issue.8 , pp. 1698-1704
    • Rudick, R.A.1    Fisher, E.2    Lee, J.-C.3    Simon, J.4    Jacobs, L.5
  • 39
    • 0033759398 scopus 로고    scopus 로고
    • The effect of interferon beta-1b treatment on MRI measures of cerebral atrophy in secondary progressive multiple sclerosis. European Study Group on Interferon beta-1b in secondary progressive multiple sclerosis
    • Molyneux, P.D. et al. The effect of interferon beta-1b treatment on MRI measures of cerebral atrophy in secondary progressive multiple sclerosis. European Study Group on Interferon beta-1b in secondary progressive multiple sclerosis. Brain 123 (Pt 11), 2256-2263 (2000).
    • (2000) Brain , vol.123 , Issue.PART 11 , pp. 2256-2263
    • Molyneux, P.D.1
  • 40
    • 77954101380 scopus 로고    scopus 로고
    • Reducing the impact of white matter lesions on automated measures of brain gray and white matter volumes
    • Chard, D.T., Jackson, J.S., Miller, D.H. & Wheeler-Kingshott, C.A. Reducing the impact of white matter lesions on automated measures of brain gray and white matter volumes. J. Magn. Reson. Imaging 32, 223-228 (2010).
    • (2010) J. Magn. Reson. Imaging , vol.32 , pp. 223-228
    • Chard, D.T.1    Jackson, J.S.2    Miller, D.H.3    Wheeler-Kingshott, C.A.4
  • 41
    • 54849431166 scopus 로고    scopus 로고
    • Gray matter atrophy in multiple sclerosis: A longitudinal study
    • Fisher, E., Lee, J.C., Nakamura, K. & Rudick, R.A. Gray matter atrophy in multiple sclerosis: a longitudinal study. Ann. Neurol. 64, 255-265 (2008).
    • (2008) Ann. Neurol. , vol.64 , pp. 255-265
    • Fisher, E.1    Lee, J.C.2    Nakamura, K.3    Rudick, R.A.4
  • 42
    • 54849431592 scopus 로고    scopus 로고
    • Gray matter atrophy is related to long-term disability in multiple sclerosis
    • Fisniku, L.K. et al. Gray matter atrophy is related to long-term disability in multiple sclerosis. Ann. Neurol. 64, 247-254 (2008).
    • (2008) Ann. Neurol. , vol.64 , pp. 247-254
    • Fisniku, L.K.1
  • 43
    • 77957363368 scopus 로고    scopus 로고
    • A longitudinal study of MRI-detected atrophy in secondary progressive multiple sclerosis
    • Furby, J. et al. A longitudinal study of MRI-detected atrophy in secondary progressive multiple sclerosis. J. Neurol. 257, 1508-1516 (2010).
    • (2010) J. Neurol. , vol.257 , pp. 1508-1516
    • Furby, J.1
  • 45
    • 77952294568 scopus 로고    scopus 로고
    • Rapid semi-automatic segmentation of the spinal cord from magnetic resonance images: Application in multiple sclerosis
    • Horsfield, M.A. et al. Rapid semi-automatic segmentation of the spinal cord from magnetic resonance images: application in multiple sclerosis. Neuroimage 50, 446-455 (2010).
    • (2010) Neuroimage , vol.50 , pp. 446-455
    • Horsfield, M.A.1
  • 46
    • 48349109469 scopus 로고    scopus 로고
    • Persistent T1 hypointensity as an MRI marker for treatment efficacy in multiple sclerosis
    • van den Elskamp, I.J. et al. Persistent T1 hypointensity as an MRI marker for treatment efficacy in multiple sclerosis. Mult. Scler. 14, 764-769 (2008)
    • (2008) Mult. Scler. , vol.14 , pp. 764-769
    • Van Den Elskamp, I.J.1
  • 47
    • 0035964157 scopus 로고    scopus 로고
    • Glatiramer acetate reduces the proportion of new MS lesions evolving into "black holes"
    • Filippi, M., Rovaris, M., Rocca, M.A., Sormani, M.P., Wolinsky, J.S. & Comi, G. Glatiramer acetate reduces the proportion of new MS lesions evolving into "black holes". Neurology 57, 731-733 (2001). (Pubitemid 32783013)
    • (2001) Neurology , vol.57 , Issue.4 , pp. 731-733
    • Filippi, M.1    Rovaris, M.2    Rocca, M.A.3    Sormani, M.P.4    Wolinsky, J.S.5    Comi, G.6
  • 49
    • 79953769528 scopus 로고    scopus 로고
    • BG-12 reduces evolution of new enhancing lesions to T1-hypointense lesions in patients with multiple sclerosis
    • MacManus, D.G. et al. BG-12 reduces evolution of new enhancing lesions to T1-hypointense lesions in patients with multiple sclerosis. J. Neurol. 258, 449-456 (2011).
    • (2011) J. Neurol. , vol.258 , pp. 449-456
    • MacManus, D.G.1
  • 51
    • 79959604087 scopus 로고    scopus 로고
    • MRI assessment of iron deposition in multiple sclerosis
    • Ropele, S. et al. MRI assessment of iron deposition in multiple sclerosis. J. Magn. Reson. Imaging 34, 13-21 (2011).
    • (2011) J. Magn. Reson. Imaging , vol.34 , pp. 13-21
    • Ropele, S.1
  • 53
    • 46849090294 scopus 로고    scopus 로고
    • Diffusion-based tractography in neurological disorders: concepts, applications, and future developments
    • DOI 10.1016/S1474-4422(08)70163-7, PII S1474442208701637
    • Ciccarelli, O., Catani, M., Johansen-Berg, H., Clark, C. & Thompson, A. Diffusionbased tractography in neurological disorders: concepts, applications, and future developments. Lancet Neurol. 7, 715-727 (2008). (Pubitemid 351957930)
    • (2008) The Lancet Neurology , vol.7 , Issue.8 , pp. 715-727
    • Ciccarelli, O.1    Catani, M.2    Johansen-Berg, H.3    Clark, C.4    Thompson, A.5
  • 54
    • 0344983758 scopus 로고    scopus 로고
    • Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia
    • DOI 10.1016/j.neuroimage.2003.07.005
    • Song, S.K., Sun, S.W., Ju, W.K., Lin, S.J., Cross, A.H. & Neufeld, A.H. Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia. Neuroimage 20, 1714-1722 (2003). (Pubitemid 37468277)
    • (2003) NeuroImage , vol.20 , Issue.3 , pp. 1714-1722
    • Song, S.-K.1    Sun, S.-W.2    Ju, W.-K.3    Lin, S.-J.4    Cross, A.H.5    Neufeld, A.H.6
  • 55
    • 84862831261 scopus 로고    scopus 로고
    • In-vivo estimates of axonal characteristics using optimized diffusion MRI protocols for single fibre orientation
    • Schneider, T., Wheeler-Kingshott, C.A. & Alexander, D.C. In-vivo estimates of axonal characteristics using optimized diffusion MRI protocols for single fibre orientation. Med. Image Comput. Comput. Assist. Interv. 13, 623-630 (2010).
    • (2010) Med. Image Comput. Comput. Assist. Interv. , vol.13 , pp. 623-630
    • Schneider, T.1    Wheeler-Kingshott, C.A.2    Alexander, D.C.3
  • 56
    • 70349673301 scopus 로고    scopus 로고
    • In vivo imaging of cortical pathology in multiple sclerosis using ultra-high field MRI
    • Mainero, C. et al. In vivo imaging of cortical pathology in multiple sclerosis using ultra-high field MRI. Neurology 73, 941-948 (2009).
    • (2009) Neurology , vol.73 , pp. 941-948
    • Mainero, C.1
  • 58
    • 84856743855 scopus 로고    scopus 로고
    • The association of intrathecal immunoglobulin synthesis and cortical lesions predicts disease activity in clinically isolated syndrome and early relapsing-remitting multiple sclerosis
    • Calabrese, M. et al. The association of intrathecal immunoglobulin synthesis and cortical lesions predicts disease activity in clinically isolated syndrome and early relapsing-remitting multiple sclerosis. Mult. Scler. 18, 174-180 (2012).
    • (2012) Mult. Scler. , vol.18 , pp. 174-180
    • Calabrese, M.1
  • 59
    • 33749488304 scopus 로고    scopus 로고
    • Magnetization transfer MRI metrics predict the accumulation of disability 8 years later in patients with multiple sclerosis
    • DOI 10.1093/brain/awl208
    • Agosta, F., Rovaris, M., Pagani, E., Sormani, M.P., Comi, G. & Filippi, M. Magnetization transfer MRI metrics predict the accumulation of disability 8 years later in patients with multiple sclerosis. Brain 129, 2620-2627 (2006). (Pubitemid 44522095)
    • (2006) Brain , vol.129 , Issue.10 , pp. 2620-2627
    • Agosta, F.1    Rovaris, M.2    Pagani, E.3    Sormani, M.P.4    Comi, G.5    Filippi, M.6
  • 60
    • 85058587810 scopus 로고    scopus 로고
    • Magnetisation transfer imaging of alemtuzumab treatment of multiple sclerosis
    • Button, T. et al. Magnetisation transfer imaging of alemtuzumab treatment of multiple sclerosis. Ann. Neurol. 17, S437 (2011).
    • (2011) Ann. Neurol. , vol.17
    • Button, T.1
  • 61
    • 77952894834 scopus 로고    scopus 로고
    • Longitudinal study of vision and retinal nerve fiber layer thickness in multiple sclerosis
    • Talman, L.S. et al. Longitudinal study of vision and retinal nerve fiber layer thickness in multiple sclerosis. Ann. Neurol. 67, 749-760 (2010).
    • (2010) Ann. Neurol. , vol.67 , pp. 749-760
    • Talman, L.S.1
  • 62
    • 4444310685 scopus 로고    scopus 로고
    • Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain
    • DOI 10.1002/ana.20202
    • Schmierer, K., Scaravilli, F., Altmann, D.R., Barker, G.J. & Miller, D.H. Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain. Ann. Neurol. 56, 407-415 (2004). (Pubitemid 39166560)
    • (2004) Annals of Neurology , vol.56 , Issue.3 , pp. 407-415
    • Schmierer, K.1    Scaravilli, F.2    Altmann, D.R.3    Barker, G.J.4    Miller, D.H.5
  • 64
    • 77953789338 scopus 로고    scopus 로고
    • Lesional magnetization transfer ratio: A feasible outcome for remyelinating treatment trials in multiple sclerosis
    • van den Elskamp, I.J. et al. Lesional magnetization transfer ratio: a feasible outcome for remyelinating treatment trials in multiple sclerosis. Mult. Scler. 16, 660-669 (2010).
    • (2010) Mult. Scler. , vol.16 , pp. 660-669
    • Van Den Elskamp, I.J.1
  • 65
    • 41649098819 scopus 로고    scopus 로고
    • Myelin water imaging of multiple sclerosis at 7 T: Correlations with histopathology
    • Laule, C., Kozlowski, P., Leung, E., Li, D.K., Mackay, A.L. & Moore, G.R. Myelin water imaging of multiple sclerosis at 7 T: correlations with histopathology. Neuroimage 40, 1575-1580 (2008).
    • (2008) Neuroimage , vol.40 , pp. 1575-1580
    • Laule, C.1    Kozlowski, P.2    Leung, E.3    Li, D.K.4    MacKay, A.L.5    Moore, G.R.6
  • 67
    • 79955379054 scopus 로고    scopus 로고
    • 1C]-2-(4'-methylaminophenyl)-6- hydroxybenzothiazole
    • 1C]-2-(4'- methylaminophenyl)-6-hydroxybenzothiazole. Ann. Neurol. 69, 673-680 (2011).
    • (2011) Ann. Neurol. , vol.69 , pp. 673-680
    • Stankoff, B.1
  • 69
    • 0344443214 scopus 로고    scopus 로고
    • Potentially adaptive functional changes in cognitive processing for patients with multiple sclerosis and their acute modulation by rivastigmine
    • DOI 10.1093/brain/awg284
    • Parry, A.M., Scott, R.B., Palace, J., Smith, S. & Matthews, P.M. Potentially adaptive functional changes in cognitive processing for patients with multiple sclerosis and their acute modulation by rivastigmine. Brain 126, 2750-2760 (2003). (Pubitemid 37463093)
    • (2003) Brain , vol.126 , Issue.12 , pp. 2750-2760
    • Parry, A.M.M.1    Scott, R.B.2    Palace, J.3    Smith, S.4    Matthews, P.M.5
  • 71
    • 0033768486 scopus 로고    scopus 로고
    • The peripheral benzodiazepine binding site in the brain in multiple sclerosis: Quantitative in vivo imaging of microglia as a measure of disease activity
    • Banati, R.B. et al. The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity. Brain 123 (Pt 11), 2321-2337 (2000).
    • (2000) Brain , vol.123 , Issue.PART 11 , pp. 2321-2337
    • Banati, R.B.1
  • 72
    • 18744407587 scopus 로고    scopus 로고
    • Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T
    • DOI 10.1093/brain/awh467
    • Srinivasan, R., Sailasuta, N., Hurd, R., Nelson, S. & Pelletier, D. Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T. Brain 128, 1016-1025 (2005). (Pubitemid 40675457)
    • (2005) Brain , vol.128 , Issue.5 , pp. 1016-1025
    • Srinivasan, R.1    Sailasuta, N.2    Hurd, R.3    Nelson, S.4    Pelletier, D.5
  • 73
    • 77349125827 scopus 로고    scopus 로고
    • MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis
    • Srinivasan, R., Ratiney, H., Hammond-Rosenbluth, K.E., Pelletier, D. & Nelson, S.J. MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis. Magn. Reson. Imaging 28, 163-170 (2010).
    • (2010) Magn. Reson. Imaging , vol.28 , pp. 163-170
    • Srinivasan, R.1    Ratiney, H.2    Hammond-Rosenbluth, K.E.3    Pelletier, D.4    Nelson, S.J.5
  • 74
    • 83255187378 scopus 로고    scopus 로고
    • Energy failure in multiple sclerosis and its investigation using MR techniques
    • Paling, D., Golay, X., Wheeler-Kingshott, C., Kapoor, R. & Miller, D. Energy failure in multiple sclerosis and its investigation using MR techniques. J. Neurol. 258, 2113-2127 (2011).
    • (2011) J. Neurol. , vol.258 , pp. 2113-2127
    • Paling, D.1    Golay, X.2    Wheeler-Kingshott, C.3    Kapoor, R.4    Miller, D.5
  • 75
    • 77950278295 scopus 로고    scopus 로고
    • Brain tissue sodium concentration in multiple sclerosis: A sodium imaging study at 3 tesla
    • Inglese, M. et al. Brain tissue sodium concentration in multiple sclerosis: a sodium imaging study at 3 tesla. Brain 133, 847-857 (2010).
    • (2010) Brain , vol.133 , pp. 847-857
    • Inglese, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.