A bursal pentapeptide (BPP-I), a novel bursal-derived peptide, exhibits antiproliferation of tumor cell and immunomodulator activity

Amino Acids

Volumn 42, Issue 6, 2012, Pages 2215-2222

  Feng, Xiu L ^a   Liu, Qing T ^b   Cao, Rui B ^a   Zhou, Bin ^a   Wang, Fang Q ^a   Deng, Wen L ^a   Qiu, Ya F ^c   Zhang, Yu ^a   Ishag, Hassan ^a   Ma, Zhi Y ^c   Zheng, Qi S ^d   Chen, Pu Y ^a  

^a NANJING AGRICULTURAL UNIVERSITY   (China)

^b Nanjing Tianbang Bio Industry Co Ltd   (China)

^c INSTITUTE OF EDIBLE FUNGI   (China)

^d Division of National Veterinary Biological   (China)

Author keywords

Antiproliferation on tumor cell; Antitumor factor p53; Bursal pentapeptide; Hybridoma cell; Immunodominant functions

Indexed keywords

AVIAN INFLUENZA VACCINE; BURSAL PENTAPEPTIDE 1; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 4; PENTAPEPTIDE; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY PRODUCTION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BURSA FABRICII; CANCER CELL CULTURE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; HYBRIDOMA; IMMUNOMODULATION; IMMUNOPHENOTYPING; IN VITRO STUDY; INHIBITION KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN LYMPHOCYTE; T LYMPHOCYTE; TUMOR CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; BURSA OF FABRICIUS; CELL LINE, TUMOR; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; CHICKENS; FEMALE; HUMANS; HYBRIDOMAS; IMMUNIZATION; INFLUENZA A VIRUS, H9N2 SUBTYPE; INFLUENZA IN BIRDS; INTERFERON-GAMMA; INTERLEUKIN-4; MICE; MICE, INBRED BALB C; OLIGOPEPTIDES; T-LYMPHOCYTES;

AVES; MUS;

EID: 84862773408     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-011-0961-8     Document Type: Article

References (26)

1. B Ann GG Douglas G Gideon 1976 Lymphocyte-differentiating hormone of bursa of Fabricius Science 193 319 321 10.1126/science.180600
2. H Arakawa JM Buerstedde 2004 Immunoglobulin gene conversion: insights from bursal B cells and the DT40 cell line Dev Dyn 229 458 464 14991701 10.1002/dvdy.10495 1:CAS:528:DC%2BD2cXislKrsL0%3D
3. V Avantika NP Kashi KS Aloukick KN Kishan KG Rakesh KP Vimal 2010 Evaluation of the MTT lymphocyte proliferation assay for the diagnosis of neurocysticercosis J Microbiol Methods 81 2 175 178 10.1016/j.mimet.2010.03.001
4. T Baba M Kita 1977 Effect of extracts of the bursa of Fabricius on IgG antibody production in hormonally bursectomized chickens Immunology 32 271 274 557452 1:CAS:528:DyaE2sXktVertbo%3D
5. EN Bou Ghanem CC Nelson SE D'Orazio 2011 T cell-intrinsic factors contribute to the differential ability of CD8+ T cells to rapidly secrete IFN-γ in the absence of antigen J Immunol 186 3 1703 1712 21191063 10.4049/jimmunol.1001960 1:CAS:528:DC%2BC3MXnsVOhsQ%3D%3D
6. L Bungener F Geeraedts W Ter Veer J Medema J Wilschut A Huckriede 2008 Alum boosts TH2-type antibody responses to whole-inactivated virus influenza vaccine in mice but does not confer superior protection Vaccine 26 19 2350 2359 18400340 10.1016/j.vaccine.2008.02.063 1:CAS:528:DC%2BD1cXls1yktLs%3D
7. JA Byrd CE Dean TK Hayes MS Wright BM Hargis 1993 Detection and partial characterization of an anti-steroidogenic peptide from the humoral immune system of the chicken Life Sci 52 1195 1207 8450712 10.1016/0024-3205(93)90102-9 1:CAS:528:DyaK3sXkt1Klsrs%3D
8. DJ Caldwell CE Dean AP McElroy DY Caldwell JG Manning BM Hargis 1999 Bursal anti-steroidogenic peptide (BASP): modulation of mitogen-stimulated bursallymphocyte DNA synthesis Comp Biochem Physiol A Mol Integr Physiol 123 4 385 391 10581703 10.1016/S1095-6433(99)00080-X 1:STN:280: DC%2BD3c%2FkvVCjtg%3D%3D
9. RB Caldwell AM Kierzek H Arakawa Y Bezzubov J Zaim P Fiedler S Kutter A Blagodatski D Kostovska M Koter J Plachy P Carninci Y Hayashizaki JM Buerstedde 2005 Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis Genome Biol 6 1 R6 15642098 10.1186/gb-2004-6-1-r6
10. Davison F, Kaspers B, Schat KA (eds) (2008) Avian Immunology, Elsevier/Academic Press, New York
11. XL Feng XD Su FQ Wang JC Wei FJ Wang RB Cao B Zhou X Mao QS Zheng PY Chen 2010 Isolation and potential immunological characterization of TPSGLVY, a novel bursal septpeptide isolated from the bursa of Fabricius Peptides 31 1562 1568 20493914 10.1016/j.peptides.2010.05.007 1:CAS:528:DC%2BC3cXptVahurg%3D
12. TF Gajewski J Chesney TJ Curriel 2009 Emerging strategies in regulatory T-cell immunotherapies Clin Adv Hematol Oncol 7 1 1 10 19288606 (quiz 11-12)
13. HP Jones YC Wang B Aldridge JM Weiss 2008 Lung and splenic B cells facilitate diverse effects on in vitro measures of antitumor immune responses Cancer Immun 8 4 18281925
14. E Kim W Deppert 2003 The complex interactions of p53 with target DNA: we learn as we go Biochem Cell Biol 81 3 141 150 12897847 10.1139/o03-046 1:CAS:528:DC%2BD3sXlvFyrtLo%3D
15. M Lacroix G Leclercq 2004 Relevance of breast cancer cell lines as models for breast tumours: an update Breast Cancer Res Treat 83 3 249 289 14758095 10.1023/B:BREA.0000014042.54925.cc 1:CAS:528:DC%2BD2cXos1Cisw%3D%3D
16. Li DY, Geng ZR, Zhu HF, Wang C, Miao DN, Chen PY (2010) Immunomodulatory activities of a new pentapeptide (Bursopentin) from the chicken bursa of Fabricius. Amino Acids. doi: 10.1007/s00726-010-0663-7
17. RD Makde JR England HP Yennawar S Tan 2010 Structure of RCC1 chromatin factor bound to the nucleosome core particle Nature 467 7315 562 566 20739938 10.1038/nature09321 1:CAS:528:DC%2BC3cXhtVKlurjF
18. P May E May 1999 Twenty years of p53 research: structural and functional aspects of the p53 protein Oncogene 18 53 7621 7636 10618702 10.1038/sj.onc.1203285 1:CAS:528:DC%2BD3cXmt1Skuw%3D%3D
19. A Nicolini A Carpi 2009 Immune manipulation of advanced breast cancer: an interpretative model of the relationship between immune system and tumor cell biology Med Res Rev 29 3 436 471 19105214 10.1002/med.20143 1:CAS:528: DC%2BD1MXlsFOns7c%3D
20. M Ohtsubo R Kai N Furuno T Sekiguchi M Sekiguchi H Hayashida K Kuma T Miyata S Fukushige T Murotsu, et al. 1987 Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation Genes Dev 1 6 585 593 3678831 10.1101/gad.1.6.585 1:STN:280:DyaL1c%2Fls1ejsg%3D%3D
21. Y Qiu Y Shen X Li Q Liu Z Ma 2008 Polyclonal antibody to porcine p53 protein: a new tool for studying the p53 pathway in a porcine model Biochem Biophys Res Commun 377 1 151 155 18840405 10.1016/j.bbrc.2008.09.117 1:CAS:528:DC%2BD1cXhtlaqsb7P
22. MJH Ratcliffe 2006 Antibodies, immunoglobulin genes and the bursa of Fabricius in chicken B cell development Dev Comp Immunol 30 101 118 16139886 10.1016/j.dci.2005.06.018 1:CAS:528:DC%2BD2MXhtVKisL7N
23. Seder RA, Paul WE, Davis MM, Fazekas de St Groth B (1992) The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4 + T cells from T cell receptor transgenic mice. J Exp Med 176(4):1091-1098
24. Y Shen X Wang L Guo Y Qiu X Li H Yu H Xiang G Tong Z Ma 2009 Influenza A virus induces p53 accumulation in a biphasic pattern Biochem Biophys Res Commun 382 2 331 335 19275889 10.1016/j.bbrc.2009.03.018 1:CAS:528:DC%2BD1MXkt1Slu7c%3D
25. VK Singh S Biswas KB Mathur W Haq SK Garg SS Agarwal 1998 Thymopentin and splenopentin as immunomodulators Immunol Res 17 345 368 9638477 10.1007/BF02786456 1:CAS:528:DyaK1cXktVSju7k%3D
26. MI Walton SC Wilson IR Hardcastle AR Mirza P Workman 2005 An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild type p53 human tumor cell lines Mol Cancer Ther 4 9 1369 1377 16170029 10.1158/1535-7163.MCT-04-0341 1:CAS:528:DC%2BD2MXhtVKnt7nI