Lovastatin modulates glycogen synthase kinase-3β pathway and inhibits mossy fiber sprouting after pilocarpine-induced status epilepticus

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Lee, Chun Yao ^a,c   Jaw, Thomas ^a   Tseng, Huan Chin ^a   Chen, I Chun ^a   Liou, Horng Huei ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c Centre de Recherche Interdisciplinaire en Biologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; DEXAMETHASONE; DIZOCILPINE; GLYCOGEN SYNTHASE KINASE 3BETA; MEVINOLIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N(G) NITROARGININE METHYL ESTER; PILOCARPINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT THERAPY; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN REGION; CELL POLARITY; CONTROLLED STUDY; CRMP 2 GENE; DENTATE GYRUS; DISEASE SEVERITY; DRUG TARGETING; EPILEPTIC STATE; EPILEPTOGENESIS; GENE; GENE EXPRESSION; GSK 3BETA GENE; HIPPOCAMPUS; HISTOPATHOLOGY; MALE; MORBIDITY; MOSSY FIBER; NERVE FIBER GROWTH; NERVE SPROUTING; NONHUMAN; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING; RECURRENT DISEASE; SEIZURE; SIGNAL TRANSDUCTION; TEMPORAL LOBE; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTICHOLESTEREMIC AGENTS; BLOTTING, WESTERN; DENTATE GYRUS; DISEASE MODELS, ANIMAL; ELECTROPHYSIOLOGY; EPILEPSY, TEMPORAL LOBE; GLYCOGEN SYNTHASE KINASE 3; LOVASTATIN; MALE; MOSSY FIBERS, HIPPOCAMPAL; MUSCARINIC AGONISTS; NERVE TISSUE PROTEINS; PILOCARPINE; RATS; RATS, WISTAR; SEIZURES; STATUS EPILEPTICUS;

EID: 84862748362     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038789     Document Type: Article

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