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Volumn 40, Issue 7, 2012, Pages 1321-1327

Neonatal development of hepatic UGT1A9: Implications of pediatric pharmacokinetics

Author keywords

[No Author keywords available]

Indexed keywords

GLUCURONOSYLTRANSFERASE 1A9; HYMECROMONE; ISOENZYME; NIFLUMIC ACID; PROPOFOL;

EID: 84862702300     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.043752     Document Type: Article
Times cited : (48)

References (40)
  • 1
    • 67649415182 scopus 로고    scopus 로고
    • Mechanistic basis of using body size and maturation to predict clearance in humans
    • Anderson BJ and Holford NHG (2009) Mechanistic basis of using body size and maturation to predict clearance in humans. Drug Metab Pharmacokinet 24:25-36.
    • (2009) Drug Metab Pharmacokinet , vol.24 , pp. 25-36
    • Anderson, B.J.1    Holford, N.H.G.2
  • 2
    • 78650267242 scopus 로고    scopus 로고
    • Developmental pharmacokinetics
    • Anderson GD (2010) Developmental pharmacokinetics. Semin Pediatr Neurol 17:208-213.
    • (2010) Semin Pediatr Neurol , vol.17 , pp. 208-213
    • Anderson, G.D.1
  • 4
    • 57349120552 scopus 로고    scopus 로고
    • Covariation of human microsomal protein per gram of liver with age: Absence of influence of operator and sample storage may justify interlaboratory data pooling
    • Barter ZE, Chowdry JE, Harlow JR, Snawder JE, Lipscomb JC, and Rostami-Hodjegan A (2008) Covariation of human microsomal protein per gram of liver with age: absence of influence of operator and sample storage may justify interlaboratory data pooling. Drug Metab Dispos 36:2405-2409.
    • (2008) Drug Metab Dispos , vol.36 , pp. 2405-2409
    • Barter, Z.E.1    Chowdry, J.E.2    Harlow, J.R.3    Snawder, J.E.4    Lipscomb, J.C.5    Rostami-Hodjegan, A.6
  • 5
    • 75749085170 scopus 로고    scopus 로고
    • An age-dependent pharmacokinetic study of intravenous and oral mycophenolate mofetil in combination with tacrolimus for GVHD prophylaxis in pediatric allogeneic stem cell transplantation recipients
    • Bhatia M, Militano O, Jin Z, Figurski M, Shaw L, Moore V, Morris E, Tallamy B, van deVen C, Ayello J, et al. (2010) An age-dependent pharmacokinetic study of intravenous and oral mycophenolate mofetil in combination with tacrolimus for GVHD prophylaxis in pediatric allogeneic stem cell transplantation recipients. Biol Blood Marrow Transplant 16:333-343.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 333-343
    • Bhatia, M.1    Militano, O.2    Jin, Z.3    Figurski, M.4    Shaw, L.5    Moore, V.6    Morris, E.7    Tallamy, B.8    Van DeVen, C.9    Ayello, J.10
  • 6
    • 77954762075 scopus 로고    scopus 로고
    • Functions and transcriptional regulation of adult human hepatic UDP-glucuronosyl- Transferases (UGTs): Mechanisms responsible for interindividual variation of UGT levels
    • Bock KW (2010) Functions and transcriptional regulation of adult human hepatic UDP-glucuronosyl- transferases (UGTs): mechanisms responsible for interindividual variation of UGT levels. Biochem Pharmacol 80:771-777.
    • (2010) Biochem Pharmacol , vol.80 , pp. 771-777
    • Bock, K.W.1
  • 9
    • 0033810470 scopus 로고    scopus 로고
    • A highly sensitive fluorescent microplate method for the determination of UDP-glucuronosyl transferase activity in tissues and placental cell lines
    • Collier AC, Tingle MD, Keelan JA, Paxton JW, and Mitchell MD (2000) A highly sensitive fluorescent microplate method for the determination of UDP-glucuronosyl transferase activity in tissues and placental cell lines. Drug Metab Dispos 28:1184-1186.
    • (2000) Drug Metab Dispos , vol.28 , pp. 1184-1186
    • Collier, A.C.1    Tingle, M.D.2    Keelan, J.A.3    Paxton, J.W.4    Mitchell, M.D.5
  • 10
    • 33745584148 scopus 로고    scopus 로고
    • Development and evaluation of a generic physiologically based pharmacokinetic model for children
    • Edginton AN, Schmitt W, and Willmann S (2006) Development and evaluation of a generic physiologically based pharmacokinetic model for children. Clin Pharmacokinet 45:1013-1034.
    • (2006) Clin Pharmacokinet , vol.45 , pp. 1013-1034
    • Edginton, A.N.1    Schmitt, W.2    Willmann, S.3
  • 11
    • 33846691233 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor1 transcription factors are essential for the UDP-glucuronosyltransferase 1A9 promoter response to hepatocyte nuclear factor 4alpha
    • Gardner-Stephen DA and Mackenzie PI (2007) Hepatocyte nuclear factor1 transcription factors are essential for the UDP-glucuronosyltransferase 1A9 promoter response to hepatocyte nuclear factor 4alpha. Pharmacogenet Genomics 17:25-36.
    • (2007) Pharmacogenet Genomics , vol.17 , pp. 25-36
    • Gardner-Stephen, D.A.1    Mackenzie, P.I.2
  • 13
    • 43049154812 scopus 로고    scopus 로고
    • The ontogeny of drug metabolism enzymes and implications for adverse drug events
    • Hines RN (2008) The ontogeny of drug metabolism enzymes and implications for adverse drug events. Pharmacol Ther 118:250-267.
    • (2008) Pharmacol Ther , vol.118 , pp. 250-267
    • Hines, R.N.1
  • 14
    • 77958093867 scopus 로고    scopus 로고
    • Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach
    • Kalthoff S, Ehmer U, Freiberg N, Manns MP, and Strassburg CP (2010) Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach. Gastroenterology 139:1699-1710.e1-2.
    • (2010) Gastroenterology , vol.139
    • Kalthoff, S.1    Ehmer, U.2    Freiberg, N.3    Manns, M.P.4    Strassburg, C.P.5
  • 15
    • 0019860388 scopus 로고
    • The prenatal and postnatal development of UDP-glucuronyltransferase activity towards bilirubin and the effect of premature birth on this activity in the human liver
    • Kawade N and Onishi S (1981) The prenatal and postnatal development of UDP-glucuronyltransferase activity towards bilirubin and the effect of premature birth on this activity in the human liver. Biochem J 196:257-260.
    • (1981) Biochem J , vol.196 , pp. 257-260
    • Kawade, N.1    Onishi, S.2
  • 16
    • 0033967508 scopus 로고    scopus 로고
    • Identification of uridine diphosphate glucuronosyltransferases involved in the metabolism and clearance of mycophenolic acid
    • Mackenzie PI (2000) Identification of uridine diphosphate glucuronosyltransferases involved in the metabolism and clearance of mycophenolic acid. Ther Drug Monit 22:10-13.
    • (2000) Ther Drug Monit , vol.22 , pp. 10-13
    • Mackenzie, P.I.1
  • 17
    • 85046981691 scopus 로고    scopus 로고
    • Protein binding predictions in infants
    • McNamara PJ and Alcorn J (2002) Protein binding predictions in infants. AAPS PharmSci 4:E4.
    • (2002) AAPS PharmSci , vol.4
    • McNamara, P.J.1    Alcorn, J.2
  • 18
    • 81855206614 scopus 로고    scopus 로고
    • A novel method for the immunoquantification of UDP- glucuronosyltransferases in human tissue
    • Milne AM, Burchell B, and Coughtrie MW (2011) A novel method for the immunoquantification of UDP-glucuronosyltransferases in human tissue. Drug Metab Dispos 39:2258-2263.
    • (2011) Drug Metab Dispos , vol.39 , pp. 2258-2263
    • Milne, A.M.1    Burchell, B.2    Coughtrie, M.W.3
  • 19
    • 79952819517 scopus 로고    scopus 로고
    • Characterization of niflumic acid as a selective inhibitor of human liver microsomal UDP-glucuronosyltransferase 1A9: Application to the reaction phenotyping of acetaminophen glucuronidation
    • Miners JO, Bowalgaha K, Elliot DJ, Baranczewski P, and Knights KM (2011) Characterization of niflumic acid as a selective inhibitor of human liver microsomal UDP-glucuronosyltransferase 1A9: application to the reaction phenotyping of acetaminophen glucuronidation. Drug Metab Dispos 39:644-652.
    • (2011) Drug Metab Dispos , vol.39 , pp. 644-652
    • Miners, J.O.1    Bowalgaha, K.2    Elliot, D.J.3    Baranczewski, P.4    Knights, K.M.5
  • 20
    • 33646077674 scopus 로고    scopus 로고
    • In vitro-in vivo correlation for drugs and other compounds eliminated by glucuronidation in humans: Pitfalls and promises
    • Miners JO, Knights KM, Houston JB, and Mackenzie PI (2006) In vitro-in vivo correlation for drugs and other compounds eliminated by glucuronidation in humans: pitfalls and promises. Biochem Pharmacol 71:1531-1539.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1531-1539
    • Miners, J.O.1    Knights, K.M.2    Houston, J.B.3    Mackenzie, P.I.4
  • 21
    • 34548099546 scopus 로고    scopus 로고
    • Pediatric development of glucuronidation: The ontogeny of hepatic UGT1A4
    • Miyagi SJ and Collier AC (2007) Pediatric development of glucuronidation: the ontogeny of hepatic UGT1A4. Drug Metab Dispos 35:1587-1592.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1587-1592
    • Miyagi, S.J.1    Collier, A.C.2
  • 22
    • 79955001140 scopus 로고    scopus 로고
    • The development of UDP-glucuronosyltransferases 1A1 and 1A6 in the pediatric liver
    • Miyagi SJ and Collier AC (2011) The development of UDP- glucuronosyltransferases 1A1 and 1A6 in the pediatric liver. Drug Metab Dispos 39:912-919.
    • (2011) Drug Metab Dispos , vol.39 , pp. 912-919
    • Miyagi, S.J.1    Collier, A.C.2
  • 23
    • 0029999059 scopus 로고    scopus 로고
    • Pharmacokinetics of propofol after a single dose in children aged 1-3 years with minor burns. Comparison of three data analysis approaches
    • Murat I, Billard V, Vernois J, Zaouter M, Marsol P, Souron R, and Farinotti R (1996) Pharmacokinetics of propofol after a single dose in children aged 1-3 years with minor burns. Comparison of three data analysis approaches. Anesthesiology 84:526-532.
    • (1996) Anesthesiology , vol.84 , pp. 526-532
    • Murat, I.1    Billard, V.2    Vernois, J.3    Zaouter, M.4    Marsol, P.5    Souron, R.6    Farinotti, R.7
  • 24
    • 0018574014 scopus 로고
    • Postnatal development of uridine diphosphate glucuronyltransferase activity towards bilirubin and 2-aminophenol in human liver
    • Onishi S, Kawade N, Itoh S, Isobe K, and Sugiyama S (1979) Postnatal development of uridine diphosphate glucuronyltransferase activity towards bilirubin and 2-aminophenol in human liver. Biochem J 184:705-707.
    • (1979) Biochem J , vol.184 , pp. 705-707
    • Onishi, S.1    Kawade, N.2    Itoh, S.3    Isobe, K.4    Sugiyama, S.5
  • 26
    • 0023879414 scopus 로고
    • A novel method for producing anti-peptide antibodies. Production of site-specific antibodies to the T cell antigen receptor beta-chain
    • Posnett DN, McGrath H, and Tam JP (1988) A novel method for producing anti-peptide antibodies. Production of site-specific antibodies to the T cell antigen receptor beta-chain. J Biol Chem 263:1719-1725.
    • (1988) J Biol Chem , vol.263 , pp. 1719-1725
    • Posnett, D.N.1    McGrath, H.2    Tam, J.P.3
  • 28
    • 33947398317 scopus 로고    scopus 로고
    • Binding of inhibitory fatty acids is responsible for the enhancement of UDP-glucuronosyltransferase 2B7 activity by albumin: Implications for in vitro-in vivo extrapolation
    • Rowland A, Gaganis P, Elliot DJ, Mackenzie PI, Knights KM, and Miners JO (2007) Binding of inhibitory fatty acids is responsible for the enhancement of UDP-glucuronosyltransferase 2B7 activity by albumin: implications for in vitro-in vivo extrapolation. J Pharmacol Exp Ther 321:137-147.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 137-147
    • Rowland, A.1    Gaganis, P.2    Elliot, D.J.3    Mackenzie, P.I.4    Knights, K.M.5    Miners, J.O.6
  • 29
    • 44149117018 scopus 로고    scopus 로고
    • The "albumin effect" and drug glucuronidation: Bovine serum albumin and fatty acid-free human serum albumin enhance the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1 and UGT1A6 activities
    • Rowland A, Knights KM, Mackenzie PI, and Miners JO (2008) The "albumin effect" and drug glucuronidation: bovine serum albumin and fatty acid-free human serum albumin enhance the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1 and UGT1A6 activities. Drug Metab Dispos 36:1056-1062.
    • (2008) Drug Metab Dispos , vol.36 , pp. 1056-1062
    • Rowland, A.1    Knights, K.M.2    Mackenzie, P.I.3    Miners, J.O.4
  • 31
  • 32
  • 33
    • 0026625085 scopus 로고
    • Characterisation of a human bilirubin UDP-glucuronosyltransferase stably expressed in hamster lung fibroblast cell cultures
    • Sutherland L, bin Senafi S, Ebner T, Clarke DJ, and Burchell B (1992) Characterisation of a human bilirubin UDP-glucuronosyltransferase stably expressed in hamster lung fibroblast cell cultures. FEBS Lett 308:161-164.
    • (1992) FEBS Lett , vol.308 , pp. 161-164
    • Sutherland, L.1    Bin Senafi, S.2    Ebner, T.3    Clarke, D.J.4    Burchell, B.5
  • 35
    • 0345549371 scopus 로고    scopus 로고
    • Evidence that unsaturated fatty acids are potent inhibitors of renal UDP-glucuronosyltransferases (UGT): Kinetic studies using human kidney cortical microsomes and recombinant UGT1A9 and UGT2B7
    • Tsoutsikos P, Miners JO, Stapleton A, Thomas A, Sallustio BC, and Knights KM (2004) Evidence that unsaturated fatty acids are potent inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human kidney cortical microsomes and recombinant UGT1A9 and UGT2B7. Biochem Pharmacol 67:191-199.
    • (2004) Biochem Pharmacol , vol.67 , pp. 191-199
    • Tsoutsikos, P.1    Miners, J.O.2    Stapleton, A.3    Thomas, A.4    Sallustio, B.C.5    Knights, K.M.6
  • 36
    • 1842536833 scopus 로고    scopus 로고
    • Human UDP-glucuronosyltransferases: Isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid
    • Uchaipichat V, Mackenzie PI, Guo XH, Gardner-Stephen D, Galetin A, Houston JB, and Miners JO (2004) Human UDP-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid. Drug Metab Dispos 32:413-423.
    • (2004) Drug Metab Dispos , vol.32 , pp. 413-423
    • Uchaipichat, V.1    Mackenzie, P.I.2    Guo, X.H.3    Gardner-Stephen, D.4    Galetin, A.5    Houston, J.B.6    Miners, J.O.7
  • 38
    • 0141519502 scopus 로고    scopus 로고
    • Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs
    • Villeneuve L, Girard H, Fortier LC, Gagné JF, and Guillemette C (2003) Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs. J Pharmacol Exp Ther 307:117-128.
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 117-128
    • Villeneuve, L.1    Girard, H.2    Fortier, L.C.3    Gagné, J.F.4    Guillemette, C.5
  • 39
  • 40
    • 33751540127 scopus 로고    scopus 로고
    • Epirubicin glucuronidation and UGT2B7 developmental expression
    • Zaya MJ, Hines RN, and Stevens JC (2006) Epirubicin glucuronidation and UGT2B7 developmental expression. Drug Metab Dispos 34:2097-2101.
    • (2006) Drug Metab Dispos , vol.34 , pp. 2097-2101
    • Zaya, M.J.1    Hines, R.N.2    Stevens, J.C.3


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