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Volumn 57, Issue 1, 2012, Pages 157-166

Exercise and non-alcoholic fatty liver disease: A systematic review and meta-analysis

Author keywords

Aerobic; NAFLD; Obesity; Physical activity; Resistance training; Weight loss

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE;

EID: 84862700268     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.02.023     Document Type: Article
Times cited : (422)

References (47)
  • 1
  • 3
    • 0028875908 scopus 로고
    • The natural history of nonalcoholic fatty liver: A follow-up study
    • Teli MR, James OFW, Burt AD, Bennett MK, Day CP. The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology 1995;22: 1714-1719.
    • (1995) Hepatology , vol.22 , pp. 1714-1719
    • Teli, M.R.1    James, O.F.W.2    Burt, A.D.3    Bennett, M.K.4    Day, C.P.5
  • 4
    • 79960549297 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease with advanced fibrosis or cirrhosis: An international collaborative study
    • Bhala N, Angulo P, van der Poorten D, Lee E, Hui JM, Saracco G, et al. The natural history of nonalcoholic fatty liver disease with advanced fibrosis or cirrhosis: an international collaborative study. Hepatology 2011;54:1208-1216.
    • (2011) Hepatology , vol.54 , pp. 1208-1216
    • Bhala, N.1    Angulo, P.2    Van Der Poorten, D.3    Lee, E.4    Hui, J.M.5    Saracco, G.6
  • 5
    • 42949178538 scopus 로고    scopus 로고
    • Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects
    • Korenblat KM, Fabbrini E, Mohammed BS, Klein S. Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. Gastroenterology 2008;134:1369-1375.
    • (2008) Gastroenterology , vol.134 , pp. 1369-1375
    • Korenblat, K.M.1    Fabbrini, E.2    Mohammed, B.S.3    Klein, S.4
  • 6
    • 25644448266 scopus 로고    scopus 로고
    • Fat in the liver and insulin resistance
    • Yki-Jarvinen H. Fat in the liver and insulin resistance. Ann Med 2005;37:347-356.
    • (2005) Ann Med , vol.37 , pp. 347-356
    • Yki-Jarvinen, H.1
  • 7
    • 77957375969 scopus 로고    scopus 로고
    • Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease current concepts
    • Targher G, Day C, Bonora E. Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease current concepts. N Engl J Med 2010;363:1341-1350.
    • (2010) N Engl J Med , vol.363 , pp. 1341-1350
    • Targher, G.1    Day, C.2    Bonora, E.3
  • 8
    • 23044442340 scopus 로고    scopus 로고
    • Drug therapy: Adherence to medication
    • Osterberg L, Blaschke T. Drug therapy: adherence to medication. N Engl J Med 2005;353:487-497.
    • (2005) N Engl J Med , vol.353 , pp. 487-497
    • Osterberg, L.1    Blaschke, T.2
  • 9
    • 80055042241 scopus 로고    scopus 로고
    • The role of thiazolidinediones in non-alcoholic steatohepatitis - A systematic review and meta analysis
    • Mahady SE, Webster AC, Walker S, Sanyal A, George J. The role of thiazolidinediones in non-alcoholic steatohepatitis - a systematic review and meta analysis. J Hepatol 2011;55:1383-1390.
    • (2011) J Hepatol , vol.55 , pp. 1383-1390
    • Mahady, S.E.1    Webster, A.C.2    Walker, S.3    Sanyal, A.4    George, J.5
  • 11
    • 77954239704 scopus 로고    scopus 로고
    • A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease
    • Musso G, Gambino R, Cassader M, Pagano G. A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease. Hepatology 2010;52:79-104.
    • (2010) Hepatology , vol.52 , pp. 79-104
    • Musso, G.1    Gambino, R.2    Cassader, M.3    Pagano, G.4
  • 12
    • 34547491854 scopus 로고    scopus 로고
    • Obesity and nonalcoholic fatty liver disease
    • Angulo P. Obesity and nonalcoholic fatty liver disease. Nutr Rev 2007;65:S57-S63.
    • (2007) Nutr Rev , vol.65
    • Angulo, P.1
  • 13
    • 77954235797 scopus 로고    scopus 로고
    • Fitness versus fatness: Moving beyond weight loss in nonalcoholic fatty liver disease
    • Johnson NA, George J. Fitness versus fatness: moving beyond weight loss in nonalcoholic fatty liver disease. Hepatology 2010;52:370-381.
    • (2010) Hepatology , vol.52 , pp. 370-381
    • Johnson, N.A.1    George, J.2
  • 16
    • 68849104744 scopus 로고    scopus 로고
    • High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease
    • Kantartzis K, Thamer C, Peter A, Machann J, Schick F, Schraml C, et al. High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease. Gut 2009;58:1281-1288.
    • (2009) Gut , vol.58 , pp. 1281-1288
    • Kantartzis, K.1    Thamer, C.2    Peter, A.3    Machann, J.4    Schick, F.5    Schraml, C.6
  • 17
    • 21544449115 scopus 로고    scopus 로고
    • Estimating the mean and variance from the median, range, and the size of a sample
    • Hozo SP, Djulbegovic B, Hozo I. Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol 2005;5.
    • (2005) BMC Med Res Methodol , vol.5
    • Hozo, S.P.1    Djulbegovic, B.2    Hozo, I.3
  • 18
    • 0031754739 scopus 로고    scopus 로고
    • The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions
    • Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health 1998;52:377-384.
    • (1998) J Epidemiol Community Health , vol.52 , pp. 377-384
    • Downs, S.H.1    Black, N.2
  • 19
    • 77949266534 scopus 로고    scopus 로고
    • The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: A randomised controlled trial
    • Finucane FM, Sharp SJ, Purslow LR, Horton K, Horton J, Savage DB, et al. The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial. Diabetologia 2010;53:624-631.
    • (2010) Diabetologia , vol.53 , pp. 624-631
    • Finucane, F.M.1    Sharp, S.J.2    Purslow, L.R.3    Horton, K.4    Horton, J.5    Savage, D.B.6
  • 20
    • 62449157280 scopus 로고    scopus 로고
    • Inflammation, hepatic enzymes and resistance training in individuals with metabolic risk factors
    • Levinger I, Goodman C, Peake J, Garnham A, Hare DL, Jerums G, et al. Inflammation, hepatic enzymes and resistance training in individuals with metabolic risk factors. Diabet Med 2009;26:220-227.
    • (2009) Diabet Med , vol.26 , pp. 220-227
    • Levinger, I.1    Goodman, C.2    Peake, J.3    Garnham, A.4    Hare, D.L.5    Jerums, G.6
  • 21
    • 34447119267 scopus 로고    scopus 로고
    • Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism
    • Shojaee-Moradie F, Baynes KCR, Pentecost C, Bell JD, Thomas EL, Jackson NC, et al. Exercise training reduces fatty acid availability and improves the insulin sensitivity of glucose metabolism. Diabetologia 2007;50:404-413.
    • (2007) Diabetologia , vol.50 , pp. 404-413
    • Shojaee-Moradie, F.1    Baynes, K.C.R.2    Pentecost, C.3    Bell, J.D.4    Thomas, E.L.5    Jackson, N.C.6
  • 22
    • 77950575040 scopus 로고    scopus 로고
    • Time course of changes in inflammatory markers during a 6-mo exercise intervention in sedentary middle-aged men: A randomized-controlled trial
    • Thompson D, Markovitch D, Betts JA, Mazzatti D, Turner J, Tyrrell RM. Time course of changes in inflammatory markers during a 6-mo exercise intervention in sedentary middle-aged men: a randomized-controlled trial. J Appl Physiol 2010;108:769-779.
    • (2010) J Appl Physiol , vol.108 , pp. 769-779
    • Thompson, D.1    Markovitch, D.2    Betts, J.A.3    Mazzatti, D.4    Turner, J.5    Tyrrell, R.M.6
  • 23
    • 80051545931 scopus 로고    scopus 로고
    • Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss
    • Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R, et al. Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. Gut 2011;60:1278-1283.
    • (2011) Gut , vol.60 , pp. 1278-1283
    • Hallsworth, K.1    Fattakhova, G.2    Hollingsworth, K.G.3    Thoma, C.4    Moore, S.5    Taylor, R.6
  • 24
    • 66749118611 scopus 로고    scopus 로고
    • The effect of an exercise training intervention on hepatic steatosis
    • Bonekamp S, Barone BB, Clark J, Stewart KJ. The effect of an exercise training intervention on hepatic steatosis. Hepatology 2008;48:1119.
    • (2008) Hepatology , vol.48 , pp. 1119
    • Bonekamp, S.1    Barone, B.B.2    Clark, J.3    Stewart, K.J.4
  • 25
    • 57149123017 scopus 로고    scopus 로고
    • Effects of therapeutic lifestyle program on ultrasound-diagnosed nonalcoholic fatty liver disease
    • Chen SM, Liu CY, Li SR, Huang HT, Tsai CY, Jou HJ. Effects of therapeutic lifestyle program on ultrasound-diagnosed nonalcoholic fatty liver disease. J Chin Med Assoc 2008;71:551-558.
    • (2008) J Chin Med Assoc , vol.71 , pp. 551-558
    • Chen, S.M.1    Liu, C.Y.2    Li, S.R.3    Huang, H.T.4    Tsai, C.Y.5    Jou, H.J.6
  • 26
    • 70350072281 scopus 로고    scopus 로고
    • Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss
    • Johnson NA, Sachinwalla T, Walton DW, Smith K, Armstrong A, Thompson MW, et al. Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. Hepatology 2009;50:1105-1112.
    • (2009) Hepatology , vol.50 , pp. 1105-1112
    • Johnson, N.A.1    Sachinwalla, T.2    Walton, D.W.3    Smith, K.4    Armstrong, A.5    Thompson, M.W.6
  • 27
  • 28
    • 78049337151 scopus 로고    scopus 로고
    • Effects of diet and physical activity interventions on weight loss and cardiometabolic risk factors in severely obese adults: A randomized trial
    • Goodpaster BH, Delany JP, Otto AD, Kuller L, Vockley J, South-Paul JE, et al. Effects of diet and physical activity interventions on weight loss and cardiometabolic risk factors in severely obese adults: a randomized trial. JAMA 2010;304:1795-1802.
    • (2010) JAMA , vol.304 , pp. 1795-1802
    • Goodpaster, B.H.1    Delany, J.P.2    Otto, A.D.3    Kuller, L.4    Vockley, J.5    South-Paul, J.E.6
  • 29
    • 44449171470 scopus 로고    scopus 로고
    • Effect of 6-month calorie restriction and exercise on serum and liver lipids and markers of liver function
    • Larson-Meyer DE, Newcomer BR, Heilbronn LK, Volaufova J, Smith SR, Alfonso AJ, et al. Effect of 6-month calorie restriction and exercise on serum and liver lipids and markers of liver function. Obesity 2008;16:1355-1362.
    • (2008) Obesity , vol.16 , pp. 1355-1362
    • De Larson-Meyer1    Newcomer, B.R.2    Heilbronn, L.K.3    Volaufova, J.4    Smith, S.R.5    Alfonso, A.J.6
  • 30
    • 72449161164 scopus 로고    scopus 로고
    • Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults
    • Silver Spring
    • Shah K, Stufflebam A, Hilton TN, Sinacore DR, Klein S, Villareal DT. Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults. Obesity (Silver Spring) 2009;17:2162-2168.
    • (2009) Obesity , vol.17 , pp. 2162-2168
    • Shah, K.1    Stufflebam, A.2    Hilton, T.N.3    Sinacore, D.R.4    Klein, S.5    Villareal, D.T.6
  • 31
    • 21244490885 scopus 로고    scopus 로고
    • Effects of diet and exercise onmuscle and liver intracellular lipid contents and insulin sensitivity in type 2 diabetic patients
    • Tamura Y, Tanaka Y, Sato F, Choi JB,Watada H, Niwa M, et al. Effects of diet and exercise onmuscle and liver intracellular lipid contents and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab 2005;90:3191-3196.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3191-3196
    • Tamura, Y.1    Tanaka, Y.2    Sato, F.3    Choi, J.B.4    Watada, H.5    Niwa, M.6
  • 32
    • 79959902659 scopus 로고    scopus 로고
    • Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: Guidance for prescribing exercise
    • Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, et al. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 2011;43:1334-1359.
    • (2011) Med Sci Sports Exerc , vol.43 , pp. 1334-1359
    • Garber, C.E.1    Blissmer, B.2    Deschenes, M.R.3    Franklin, B.A.4    Lamonte, M.J.5    Lee, I.M.6
  • 33
    • 75749084440 scopus 로고    scopus 로고
    • A 12-week aerobic exercise program reduces hepatic fat accumulation and insulin resistance in obese, Hispanic adolescents
    • van der Heijden GJ, Wang ZJ, Chu ZD, Sauer PJ, Haymond MW, Rodriguez LM, et al. A 12-week aerobic exercise program reduces hepatic fat accumulation and insulin resistance in obese, Hispanic adolescents. Obesity 2010;18:384-390.
    • (2010) Obesity , vol.18 , pp. 384-390
    • Van Der Heijden, G.J.1    Wang, Z.J.2    Chu, Z.D.3    Sauer, P.J.4    Haymond, M.W.5    Rodriguez, L.M.6
  • 34
  • 35
    • 41549108440 scopus 로고    scopus 로고
    • Effect of lifestyle intervention on non-alcoholic fatty liver disease in Chinese obese children
    • Wang CL, Liang L, Fu JF, Zou CC, Hong F, Xue JZ, et al. Effect of lifestyle intervention on non-alcoholic fatty liver disease in Chinese obese children. World J Gastroenterol 2008;14:1598-1602.
    • (2008) World J Gastroenterol , vol.14 , pp. 1598-1602
    • Wang, C.L.1    Liang, L.2    Fu, J.F.3    Zou, C.C.4    Hong, F.5    Xue, J.Z.6
  • 36
    • 34648836960 scopus 로고    scopus 로고
    • Weight-loss outcomes: A systematic review and meta-analysis of weightloss clinical trials with a minimum 1-year follow-up
    • Franz MJ, VanWormer JJ, Crain AL, Boucher JL, Histon T, Caplan W, et al. Weight-loss outcomes: a systematic review and meta-analysis of weightloss clinical trials with a minimum 1-year follow-up. J Am Diet Assoc 2007;107:1755-1767.
    • (2007) J Am Diet Assoc , vol.107 , pp. 1755-1767
    • Franz, M.J.1    VanWormer, J.J.2    Crain, A.L.3    Boucher, J.L.4    Histon, T.5    Caplan, W.6
  • 37
    • 84858703583 scopus 로고    scopus 로고
    • Omega-3 supplementation and non-alcoholic natty liver disease: A systematic review and meta-analysis
    • Parker HM, Johnson NA, Burdon KA, Cohn JS, OConnor HT, George J. Omega-3 supplementation and non-alcoholic natty liver disease: a systematic review and meta-analysis. J Hepatol 2011;56:944-951.
    • (2011) J Hepatol , vol.56 , pp. 944-951
    • Parker, H.M.1    Johnson, N.A.2    Burdon, K.A.3    Cohn, J.S.4    OConnor, H.T.5    George, J.6
  • 39
    • 65249156393 scopus 로고    scopus 로고
    • Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury
    • see comment
    • Thyfault JP, Rector RS, Uptergrove GM, Borengasser SJ, Morris EM, Wei Y, et al. Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury [see comment]. J Physiol 2009;587:1805-1816.
    • (2009) J Physiol , vol.587 , pp. 1805-1816
    • Thyfault, J.P.1    Rector, R.S.2    Uptergrove, G.M.3    Borengasser, S.J.4    Morris, E.M.5    Wei, Y.6
  • 40
    • 51749108218 scopus 로고    scopus 로고
    • Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats
    • Lond
    • Rector RS, Thyfault JP, Laye MJ, Morris RT, Borengasser SJ, Uptergrove GM, et al. Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. J Physiol (Lond) 2008;586:4241-4249.
    • (2008) J Physiol , vol.586 , pp. 4241-4249
    • Rector, R.S.1    Thyfault, J.P.2    Laye, M.J.3    Morris, R.T.4    Borengasser, S.J.5    Uptergrove, G.M.6
  • 41
    • 33645225309 scopus 로고    scopus 로고
    • Effect of exercise and dietary modification on serum aminotransferase levels in patients with nonalcoholic steatohepatitis [see comment]
    • Sreenivasa Baba C, Alexander G, Kalyani B, Pandey R, Rastogi S, Pandey A, et al. Effect of exercise and dietary modification on serum aminotransferase levels in patients with nonalcoholic steatohepatitis [see comment]. J Gastroenterol Hepatol 2006;21:191-198.
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 191-198
    • Sreenivasa Baba, C.1    Alexander, G.2    Kalyani, B.3    Pandey, R.4    Rastogi, S.5    Pandey, A.6
  • 42
    • 67651146947 scopus 로고    scopus 로고
    • Independent effects of physical activity in patients with nonalcoholic fatty liver disease
    • St George A, Bauman A, Johnston A, Farrell G, Chey T, George J. Independent effects of physical activity in patients with nonalcoholic fatty liver disease. Hepatology 2009;50:68-76.
    • (2009) Hepatology , vol.50 , pp. 68-76
    • St George, A.1    Bauman, A.2    Johnston, A.3    Farrell, G.4    Chey, T.5    George, J.6
  • 43
    • 80051971972 scopus 로고    scopus 로고
    • Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals
    • Rabol R, Petersen KF, Dufour S, Flannery C, Shulman GI. Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals. Proc Natl Acad Sci USA 2011;108:13705-13709.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 13705-13709
    • Rabol, R.1    Petersen, K.F.2    Dufour, S.3    Flannery, C.4    Shulman, G.I.5
  • 44
  • 45
    • 0035799806 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    • Tuomilehto J, Lindstrom J, Eriksson J, Valle TT, Hamalainen H, Ilanne-Parikka P. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001;344:1343-1350.
    • (2001) N Engl J Med , vol.344 , pp. 1343-1350
    • Tuomilehto, J.1    Lindstrom, J.2    Eriksson, J.3    Valle, T.T.4    Hamalainen, H.5    Ilanne-Parikka, P.6
  • 46
    • 83855164069 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of the effect of aerobic vs. resistance exercise training on visceral fat
    • Ismail I, Keating SE, Baker MK, Johnson NA. A systematic review and meta-analysis of the effect of aerobic vs. resistance exercise training on visceral fat. Obes Rev 2011. http://dx.doi.org/10.1111/j.1467-789X.2011.00931.x.
    • (2011) Obes Rev
    • Ismail, I.1    Keating, S.E.2    Baker, M.K.3    Johnson, N.A.4
  • 47
    • 0034730069 scopus 로고    scopus 로고
    • Physical activity and coronary heart disease in men - The Harvard Alumni Health Study
    • Sesso HD, Paffenbarger RS, Lee IM. Physical activity and coronary heart disease in men - the Harvard Alumni Health Study. Circulation 2000;102:975-980.
    • (2000) Circulation , vol.102 , pp. 975-980
    • Sesso, H.D.1    Paffenbarger, R.S.2    Lee, I.M.3


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