Gene expression signatures in the peripheral blood after radiosurgery of human cerebral arteriovenous malformations

Strahlentherapie und Onkologie

Volumn 186, Issue 2, 2010, Pages 91-98

  Bois, Angelika Zabel Du ^a,b   Wagner Ecker, Mechthild ^a   Milker Zabel, Stefanie ^b   Schwager, Christian ^a   Wirkner, Ute ^a   Debus, Jürgen ^b   Abdollahi, Amir ^a,b,c   Huber, Peter E ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c ST ELIZABETH'S MEDICAL CENTER   (United States)

Author keywords

Angiogenesis; Arteriovenous malformation; Gene expression; Molecular markers; Radiosurgery

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENTARY DNA; CYCLIN DEPENDENT KINASE 6; MESSENGER RNA; NEUROPILIN 2; PLASMINOGEN ACTIVATOR INHIBITOR 3; STAT3 PROTEIN; TOLL LIKE RECEPTOR 4;

ADULT; AGED; ANTIANGIOGENIC ACTIVITY; ARTICLE; BLOOD CLOTTING; BRAIN ARTERIOVENOUS MALFORMATION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; FEMALE; FOLLOW UP; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; HUMAN; MALE; MOLECULAR BIOLOGY; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; RADIODIAGNOSIS; RADIOSURGERY; TRANSCRIPTOMICS; VENOUS BLOOD;

EID: 77950797001     PISSN: 01797158     EISSN: 1439099X     Source Type: Journal    
DOI: 10.1007/s00066-010-2034-4     Document Type: Article

References (34)

1. 1. Abdollahi A, Schwager C, Kleeff J, et al. Transcriptional network governing the angiogenic switch in human pancreatic carcinoma. PNAS 2007;104:12890-12895 (Pubitemid 47255250)
2. Abiatari I, DeOliveira T, Kerkadze V, et al. Consensus transcriptome signature of perineural invasion in pancreatic carcinoma. Mol Cancer Ther 2009;8:1494-1504
3. Almog N, Ma L, Raychowdhury R, et al. Transcriptional switch of dormant tumors to fast-growing angiogenic phenotype. Cancer Res 2009;69:836-844
4. 4. Bromberg J, Darnell Jr JE. The role of STATs in transcriptional control and their impact on cellular function. Oncogene 2000;19:2468-2473 (Pubitemid 30339202)
5. Capalbo G, Rödel C, Stauber RH, et al. The role of survivin for radiation therapy. Prognostic and predictive factor and therapeutic target [Review]. Strahlenther Onkol 2007;183:593-599
6. Domhan S, Muschal S, Schwager C, et al. Molecular mechanisms of the antiangiogenic and antitumor effects of mycophenolic acid. Mol Cancer Ther 2008;7:1656-1668
7. 7. Favier B, Alam A, Barron P, et al. Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration. Blood 2006;108:1243-1250 (Pubitemid 44232021)
8. Frendeus B, Wachtler C, Hedlund M, et al. Escherichia coli P fimbriae utilize the toll-like receptor 4 pathway for cell activation. Mol Microbiol 2001;40:37-51.
9. GabryśD, Dörfler A, Yaromina A, et al. Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo. Strahlenther Onkol 2008;184:48-53.
10. 10. Germeyer A, Hamilton AE, Laughlin LS, et al. Cellular expression and hormonal regulation of neuropilin-1 and -2 messenger ribonucleic acid in the human and rhesus macaque endometrium. J Clin Endocrinol Metab 2005;90:1783-1790 (Pubitemid 40464052)
11. 11. Gluzman-Poltorak Z, Cohen T, Herzog Y, et al. Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165 [Erratum in: J Biol Chem 2000;275:29922]. J Biol Chem 2000;275: 18040-18045 (Pubitemid 32043878)
12. 12. Grossel MJ, Hinds PW. From cell cycle to differentiation: an expanding role for cdk6. Cell Cycle 2006;5:266-270 (Pubitemid 43213495)
13. 13. Hashimoto T, Lam T, Boudreau NJ, et al. Abnormal balance in the angiopoietin-tie2 system in human brain arteriovenous malformations. Circ Res 2001;89:111-113 (Pubitemid 34135816)
14. 14. Kader A, Goodrich JT, Sonstein WJ, et al. Recurrent cerebral arteriovenous malformations after negative postoperative angiograms. J Neurosurg 1996;85:14-18 (Pubitemid 26195032)
15. Kolodkin AL, Levengood DV, Rowe EG, et al. Neuropilin is a semaphorin III receptor. Cell 1997;90:753-762
16. 16. Lanza V, Pretazzoli V, Olivieri G, et al. Transcriptional response of human umbilical vein endothelial cells to low doses of ionizing radiation. J Radiat Res (Tokyo) 2005;46:265-276 (Pubitemid 41190664)
17. Milker-Zabel S, Bois AZ, Ranai G, et al. SU11657 enhances radiosensitivity of human meningioma cells. Int J Radiat Oncol Biol Phys 2008;70:1213-1218
18. 18. Moretti S, Procopio A, Boemi M, et al. Neuronal semaphorins regulate a primary immune response. Curr Neurovasc Res 2006;3:295-305. (Pubitemid 44706254)
19. Niyazi M, Marini P, Daniel PT, et al. Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade. Strahlenther Onkol 2009;185:8-18.
20. 20. Pollock BE, Flickinger JC. A proposed radiosurgery-based grading system for arteriovenous malformations. J Neurosurg 2002;96:79-85. (Pubitemid 34229990)
21. Pollock BE, Gorman DA, Coffey RJ. Patient outcomes after arteriovenous malformation radiosurgical management: results based on a 5- to 14-year follow-up study. Neurosurgery 2003;52:1291-1297
22. Rades D, Golke H, Schild SE, et al. Impact of VEGF and VEGF receptor 1 (FLT1) expression on the prognosis of stage III esophageal cancer patients after radiochemotherapy. Strahlenther Onkol 2008;184:416-420
23. 23. Rödel C, Sauer R. Integration of novel agents into combined-modality treatment for rectal cancer patients [Review]. Strahlenther Onkol 2007;183: 227-235 (Pubitemid 46725993)
24. 24. Saltzman A, Stone M, Franks C, et al. Cloning and characterization of human Jak-2 kinase: high mRNA expression in immune cells and muscle tissue. Biochem Biophys Res Commun 1998;246:627-633 (Pubitemid 28420909)
25. 25. Schütze C, Dörfler A, Eicheler W, et al. Combination of EGFR/HER2 tyrosine kinase inhibition by BIBW 2992 and BIBW 2669 with irradiation in FaDu human squamous cell carcinoma. Strahlenther Onkol 2007;183:256-264 (Pubitemid 46725991)
26. Schwager C, Wirkner U, Abdollahi A, et al. TableButler - a Windows based tool for processing large data tables generated with high-throughput methods. BMC Bioinformatics 2009;10:235.
27. 27. Seki E, De Minicis S, Österreicher CH, et al. TLR4 enhances TGF-β signaling and hepatic fibrosis. Nat Med 2007;13:1324-1332 (Pubitemid 350073596)
28. 28. Spetzler RF, Martin NA. A proposed grading system for arteriovenous malformations. J Neurosurg 1986;65:476-483 (Pubitemid 16000693)
29. Steiner L, Lindquist C, Adler JR, et al. Clinical outcome of radiosurgery for cerebral arteriovenous malformations. J Neurosurg 1992;77:1-8.
30. 30. Sulpice E, Plouët J, Bergé M, et al. Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity. Blood 2008;111: 2036-2045 (Pubitemid 351451514)
31. 31. Takashima S, Kitakaze M, Asakura M, et al. Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis. Proc Natl Acad Sci U S A 2002;99:3657-3662 (Pubitemid 34252162)
32. Watanabe R, Wada H, Sakakura M, et al. Plasma levels of activated protein C-protein C inhibitor complex in patients with hypercoagulable states. Am J Hematol 2000;65:35-40.
33. 33. Zabel A, Milker-Zabel S, Huber P, et al. Treatment outcome after linac-based radiosurgery in cerebral arteriovenous malformations: retrospective analysis of factors affecting obliteration. Radiother Oncol 2005;77:105-110 (Pubitemid 41503398)
34. Zabel-du Bois A, Ackermann B, Hauswald H, et al. Influence of i.v. contrast agent on dose calculation in 3-D treatment planning for radiosurgery of cerebral arteriovenous malformations. Strahlenthe Oncol 2009;185: 318-324