Investigation of the component of Lycopodium serratum extract that inhibits proliferation and mediates apoptosis of human HL-60 leukemia cells

Food and Chemical Toxicology

Volumn 50, Issue 8, 2012, Pages 2629-2634

  Ham, Young Min ^a   Yoon, Weon Jong ^a   Park, Soo Yeong ^a   Jung, Yong Hwan ^a   Kim, Daekyung ^b   Jeon, You Jin ^c   Wijesinghe, W A J P ^c   Kang, Sung Myung ^c   Kim, Kil Nam ^a  

^a Jeju Biodiversity Research Institute   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

^c Jeju National University   (South Korea)

Author keywords

Anti cancer; Apoptosis; HL 60 cells; Lycopodium serratum; Ratio of Bax Bcl xL

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYTOCHROME C; DNA; LYCOPODIUM SERRATUM EXTRACT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL XL; SERRATENEDIOL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME RELEASE; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYCOPODIUM; PROTEIN CLEAVAGE;

APOPTOSIS; CELL PROLIFERATION; HL-60 CELLS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; LYCOPODIUM; PLANT EXTRACTS;

HUPERZIA SERRATA SERRATA;

EID: 84862680868     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.05.019     Document Type: Article

References (34)

1. Bold R.J., Termuhlen P.M., McConkey D.J. Apoptosis, cancer and cancer therapy. Surg. Oncol. 1997, 6:133-142.
2. Budihardjo I., Oliver H., Lutter M., Luo X., Wang X. Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Biol. 1999, 15:269-290.
3. Chiu L.C.M., Elaine T.S.H., Wong Y.L., Ooi V.E.C. Ethyl acetate extract of Patrinia scabiosaefolia downregulates anti-apoptotic Bcl-2/Bcl-XL expression, and induces apoptosis in human breast carcinoma MCF-7 cells independent of caspase-9 activation. J. Ethnopharmacol. 2006, 105:263-268.
4. Cory S., Adams J.M. The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2002, 2:647-656.
5. Doi K., Sakai K., Tanaka R., Toma K., Yamaguchi T., Wei M., Fukushima S., Wanibuchi H. Chemopreventive effects of 13α, 14α-epoxy-3β-methoxyserratan-21β-ol (PJJ-34), a serratane-type triterpenoid, in a rat multi-organ carcinogenesis bioassay. Cancer Lett. 2010, 289:161-169.
6. Fernandes-Alnemri T., Litwack G., Alnemri E.S. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein CED-3 and mammalian interleukin-1 beta-converting enzyme. J. Biol. Chem. 1994, 269:30761-30764.
7. Gschwind M., Huber G. Apoptotic cell death induced by β-amyloid 1-42 peptide is cell type dependent. J. Neurochem. 1995, 65:292-300.
8. Kang M.H., Reynolds C.P. Bcl-2 inhibitor: targeting mitochondrial apoptotic pathways in cancer therapy. Clin. Cancer Res. 2009, 15:1126-1132.
9. Kim K.N., Heo S.J., Kang S.M., Ahn G., Jeon Y.J. Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway. Toxicol. In Vitro 2010, 24:1648-1654.
10. Konopleva M., Mikhail A., Estrov Z., Zhao S., Harris D., Sanchez-Williams G., Kornblau S.M., Dong J., Kliche K.O., Jiang S., Snodgrass H.R., Estey E.H., Andreeff M. Expression and function of leptin receptor isoforms in myeloid leukemia and myelodysplastic syndromes: proliferative and antiapoptotic activities. Blood 1999, 93:1668-1676.
11. Kufe D.W., Pollock R.E., Weichselbaum R.R., Bast R.C., Gansier T.S., Holland J.F. Cancer medicine 2003, American Cancer Society Inc., and B.C. Decker, Inc., Hamilton, Ontario. 6th ed.
12. Lawrence G.H.M. Taxonomy of Vascular Plants 1989, MacMillan Publishing Co., New York, USA, pp. 337-338.
13. Lee T.B. Coloured Flora of Korea 2003, Hyangmoon Publishing Co., Seoul, Korea, p 15.
14. Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP dependent formation of Apaf-1/caspase-9 complex initates an apoptotic protease cascade. Cell 1997, 81:479-489.
15. Lizard G., Fournel S., Genestier L., Dhedin N., Chaput C., Flacher M., Mutin M., Panaye G., Revillard J.P. Kinetics of plasma membrane and mitochondrial alterations in the cells undergoing apoptosis. Cytometry 1995, 21:275-283.
16. Lowe S.W., Lin A.W. Apoptosis in cancer. Carcinogenesis 2000, 21:485-495.
17. Miller N., Hootele C., Braekman J.C. Triterpenoids of Lycopodium megastachyum. Phytochemistry 1973, 12:1759-1761.
18. National Statistical Office, Korea, 2008. Korean Statistical Information System. Available from: http://kosis.nso.go.kr.
19. Nicoletti I., Migliorati G., Pagliacci M.C., Grignani F., Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 1991, 139:271-279.
20. Oliver F.J., de la Rubia G., Rolli V., Ruiz-Ruiz M.C., de Murcia G., Urcia J.M. Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis lesson from an uncleavable mutant. J. Biol. Chem. 1998, 273:33533-33539.
21. Sano T., Tsuda Y., Inubushi Y. Structures of tohogenol and tohogeninol: triterpenoids of Lycopodium serratum. Tetrahedron 1970, 26:2981-2986.
22. Seto H., Furihata K., Guangyi X., Xiong C., Deji P. Assignments of the 1H- and 13C-NMR spectra of four lycopodium triterpenoids by the application of a new two-dimensional technique, heteronuclear multiple bond connectivity (HMBC). Agric. Biol. Chem. 1988, 52:1797-1801.
23. Tanaka R., Minami T., Ishikawa Y., Matsunaga S., Tokuda H., Nishino H. Cancer chemopreventive activity of serratane-type triterpenoids on two-stage mouse skin carcinogenesis. Cancer Lett. 2003, 196:121-126.
24. Thees S., Hubbard G.B., Winckler J., Schultz C., Rami A. Specific alteration of the Bax/Bcl2 ratio and cytochrome c without execution of apoptosis in the hippocampus of aged baboons. Restor. Neurol. Neuros. 2005, 23:1-9.
25. Vickers A. Botanical medicines for the treatment of cancer: rationale, overview of current data, and methodological considerations for phase I and II trials. Cancer Invest. 2002, 20:1069-1079.
26. Wang X.W., Zhan Q., Coursen J.D., Khan M.A., Kontny H.U., Yu L., Hollander M.C., O'Connor P.M., Fornace A.J., Harris C.C. GADD45 induction of a G2/M cell cycle checkpoint. Proc. Natl. Acad. Sci. USA 1999, 96:3706-3711.
27. Xiang Y., Yang S.P., Zhan Z.J., Yue J.M. Terpenoids and phenols from Taiwania flousiana. Acta Botanica Sinica 2004, 46:1002-1008.
28. Xu Y., Ge R., Du J., Xin H., Yi T., Sheng J., Wang Y., Ling C. Corosolic acid induces apoptosis through mitochondrial pathway and caspases activation in human cervix adenocarcinoma HeLa cells. Cancer Lett. 2009, 284:229-237.
29. Yamaguchi C., Wanibuchi H., Kakehashi A., Tanaka R., Fukushima S. Chemopreventive effects of a serratanetype triterpenoid, 3a-methoxyserrat-14-en-21b-ol (PJ-1), against rat lung carcinogenesis. Food Chem. Toxicol. 2008, 46:1882-1888.
30. Yan Y., Su X., Liang Y., Zhang J., Shi C., Lu Y., Gu L., Fu L. Emodinazide methyl anthraquinone derivative trigger mitochondrial-dependent cell apoptosis involving in caspase-8-midiated Bid cleavage. Mol. Cancer Ther. 2008, 7:1688-1697.
31. Yang L.L., Lee C.Y., Yen K.Y. Induction of apoptosis by hydrolsable tannins from Eugenia jambos L. on human leukemia cells. Cancer Lett. 2000, 157:65-75.
32. Yoshimoto, M., Okuno, S., Suwa, S.T., Yamakawa, O., 2002. Effect of harvest time on nutrient content of sweetpotato leaves. 12th Symposium on International Society of Tropical Root Crops. pp. 312-323.
33. Zhou H., Li Y.S., Tong X.T., Liu H.Q., Jiang S.H., Zhu D.Y. Serratane-type triterpenoids from Huperzia serrata. Nat. Prod. Res. 2004, 18:453-459.
34. Zinkel S., Gross A., Yang E. Bcl-2 family in DNA damage and cell cycle control. Cell Death Differ. 2006, 13:1351-1359.