Influence of isotretinoin on hippocampal-based learning in human subjects

Psychopharmacology

Volumn 221, Issue 4, 2012, Pages 667-674

  Ormerod, Anthony D ^a   Thind, Chamandeep K ^c   Rice, Shantini A ^c   Reid, Ian C ^a   Williams, Justin H G ^a   McCaffery, Peter J A ^b  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c ABERDEEN ROYAL INFIRMARY   (United Kingdom)

Author keywords

CANTAB; Hippocampus; Isotretinoin; Learning; Memory; Retinoic acid

Indexed keywords

ISOTRETINOIN; RETINOIC ACID;

ACNE VULGARIS; ADULT; ARTICLE; BECK DEPRESSION INVENTORY; BRAIN FUNCTION; BRAIN REGION; CLINICAL ARTICLE; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; CORRELATIONAL STUDY; DEPTH PERCEPTION; FEMALE; GLOBAL ACNE GRADE; HIPPOCAMPUS; HUMAN; LEARNING; MALE; MEMORY; NEUROLOGIC EXAMINATION; OBSERVATIONAL STUDY; PRIORITY JOURNAL; SCORING SYSTEM; TASK PERFORMANCE;

ACNE VULGARIS; ADMINISTRATION, ORAL; ADOLESCENT; ADULT; DERMATOLOGIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HIPPOCAMPUS; HUMANS; ISOTRETINOIN; LEARNING; MALE; MEMORY; NEUROPSYCHOLOGICAL TESTS; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84862659963     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-011-2611-y     Document Type: Article

References (46)

1. Aoto J, Nam CI, PoonMM, Ting P, Chen L (2008) Synaptic signaling by all-trans retinoic acid in homeostatic synaptic plasticity. Neuron 60:308-320
2. Balmer JE, Blomhoff R (2002) Gene expression regulation by retinoic acid. J Lipid Res 43:1773-1808
3. Bremner JD, McCaffery P (2008) The neurobiology of retinoic acid in affective disorders. Prog Neuropsychopharmacol Biol Psychiatry 32:315-331
4. Bremner JD, Shearer KD, McCaffery PJ (2011) Retinoic acid and affective disorders: the evidence for an association. J Clin Psychiatry. doi:10.4088/JCP.10r05993
5. Chiang MY, Misner D, Kempermann G, Schikorski T, Giguere V, Sucov HM, Gage FH, Stevens CF, Evans RM (1998) An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression. Neuron 21:1353-1361
6. Cocco S, Diaz G, Stancampiano R, Diana A, Carta M, Curreli R, Sarais L, Fadda F (2002) Vitamin A deficiency produces spatial learning and memory impairment in rats. Neuroscience 115:475-482
7. Corcoran JP, So PL, Maden M (2004) Disruption of the retinoid signalling pathway causes a deposition of amyloid beta in the adult rat brain. Eur J Neurosci 20:896-902
8. Crandall J, SakaiY, Zhang J,Koul O, MineurY, CrusioWE, McCaffery P (2004) 13-cis-Retinoic acid suppresses hippocampal cell divisionand hippocampal-dependent learning in mice. Proc Natl Acad Sci U S A 101:5111-5116
9. Dere E, Pause BM, Pietrowsky R (2010) Emotion and episodic memory in neuropsychiatric disorders. Behav Brain Res 215:162-171
10. Ding Y, Qiao A,Wang Z, Goodwin JS, Lee ES, Block ML, Allsbrook M, McDonald MP, Fan GH (2008) Retinoic acid attenuates betaamyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J Neurosci 28:11622-11634
11. Dopheide MM, Morgan RE (2008) Isotretinoin (13-cis-retinoic acid) alters learning and memory, but not anxiety-like behavior, in the adult rat. Pharmacol Biochem Behav 91:243-251
12. Enderlin V, Pallet V, Alfos S, Dargelos E, Jaffard R, Garcin H, Higueret P (1997) Age-related decreases in mRNA for brain nuclear receptors and target genes are reversed by retinoic acid treatment. Neurosci Lett 229:125-129
13. Ergun T, Seckin D, Ozaydin N, Bakar O, Comert A, Atsu N, Demircay Z, Yoney H, Zaimoglu S (2011) Isotretinoin has no negative effect on attention, executive function and mood. J Eur Acad Dermatol Venereol. doi:10.1111/j.1468- 3083.2011.04089.x
14. Etchamendy N, Enderlin V,Marighetto A, VouimbaRM, Pallet V, Jaffard R, Higueret P (2001) Alleviation of a selective age-related relational memory deficit in mice by pharmacologically induced normalization of brain retinoid signaling. J Neurosci 21:6423-6429
15. Fairhall SL, Sharma S, Magnusson J, Murphy B (2010) Memory related dysregulation of hippocampal function inmajor depressive disorder. Biol Psychol 85:499-503
16. Falconer DW, Cleland J, Fielding S, Reid IC (2010) Using the Cambridge Neuropsychological Test Automated Battery (CANTAB) to assess the cognitive impact of electroconvulsive therapy on visual and visuospatial memory. Psychol Med 40:1017-1025
17. Fowler KS, Saling MM, Conway EL, Semple JM, Louis WJ (2002) Paired associate performance in the early detection of DAT. J Int Neuropsychol Soc 8:58-71
18. Goodfield MJ, Cox NH, Bowser A, McMillan JC, Millard LG, Simpson NB, Ormerod AD (2010) Advice on the safe introduction and continued use of isotretinoin in acne in the U.K. Br J Dermatol 162:1172-1179
19. Goodman AB, Pardee AB (2003) Evidence for defective retinoid transport and function in late onset Alzheimer's disease. Proc Natl Acad Sci U S A 100:2901-2905
20. Halvorsen JA, Stern RS, Dalgard F, Thoresen M, Bjertness E, Lien L (2011) Suicidal ideation, mental health problems, and social impairment are increased in adolescents with acne: a population-based study. J Invest Dermatol 131:363-370
21. Imayoshi I, Sakamoto M, Ohtsuka T, Takao K, Miyakawa T, Yamaguchi M, Mori K, Ikeda T, Itohara S, Kageyama R (2008) Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nat Neurosci 11:1153-1161
22. Jacobs S, Lie DC, Decicco KL, Shi Y, Deluca LM, Gage FH, Evans RM (2006) Retinoic acid is required early during adult neurogenesis in the dentate gyrus. Proc Natl Acad Sci U S A 103:3902-3907
23. Jessberger S, Clark RE, Broadbent NJ, Clemenson GD Jr, Consiglio A, Lie DC, Squire LR, Gage FH (2009) Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. Learn Mem 16:147-154
24. Kontaxakis VP, Skourides D, Ferentinos P, Havaki-Kontaxaki BJ, Papadimitriou GN (2009) Isotretinoin and psychopathology: a review. Ann Gen Psychiatry 8:2
25. Lowe C, Rabbitt P (1998) Test/re-test reliability of the CANTAB and ISPOCD neuropsychological batteries: theoretical and practical issues. Cambridge neuropsychological test automated battery. International study of post-operative cognitive dysfunction. Neuropsychologia 36:915-923
26. MacQueen G, Frodl T (2011) The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research? Mol Psychiatry 16:252-264
27. McCaffery PJ, Adams J, Maden M, Rosa-Molinar E (2003) Too much of a good thing: retinoic acid as an endogenous regulator of neural differentiation and exogenous teratogen. Eur J Neurosci 18:457-472
28. McCaffery P, Zhang J, Crandall JE (2006) Retinoic acid signaling and function in the adult hippocampus. J Neurobiol 66:780-791
29. Misner DL, Jacobs S, Shimizu Y, de Urquiza AM, Solomin L, Perlmann T, De Luca LM, Stevens CF, Evans RM (2001) Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity. Proc Natl Acad Sci U S A 98:11714-11719
30. Nelson AM, Gilliland KL, Cong Z, Thiboutot DM (2006) 13-cis Retinoic acid induces apoptosis and cell cycle arrest in human SEB-1 sebocytes. J Invest Dermatol 126:2178-2189
31. Nelson AM, Zhao W, Gilliland KL, Zaenglein AL, Liu W, Thiboutot DM (2009) Temporal changes in gene expression in the skin of patients treated with isotretinoin provide insight into its mechanism of action. Dermatoendocrinol 1:177-187
32. Olson CR, Mello CV (2010) Significance of vitamin A to brain function, behavior and learning. Mol Nutr Food Res 54:489-495
33. Poon MM, Chen L (2008) Retinoic acid-gated sequence-specific translational control by RARalpha. Proc Natl Acad Sci U S A 105:20303-20308
34. Porter RJ, Barnett NA, Idey A, McGuckin EA, O'Brien JT (2002) Effects of hydrocortisone administration on cognitive function in the elderly. J Psychopharmacol 16:65-71
35. Pozo K, Goda Y (2010) Unraveling mechanisms of homeostatic synaptic plasticity. Neuron 66:337-351
36. Rochette-Egly C, Germain P (2009) Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs). Nucl Recept Signal 7:e005
37. Sahay A, Scobie KN, Hill AS, O'Carroll CM, Kheirbek MA, Burghardt NS, Fenton AA, Dranovsky A, Hen R (2011) Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature 472:466-470
38. Sakai Y, Crandall JE, Brodsky J, McCaffery P (2004) 13-cis Retinoic acid (accutane) suppresses hippocampal cell survival in mice. Ann N Y Acad Sci 1021:436-440
39. Saxe MD, Battaglia F, Wang JW, Malleret G, David DJ, Monckton JE, Garcia AD, Sofroniew MV, Kandel ER, Santarelli L, Hen R, Drew MR (2006) Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proc Natl Acad Sci U S A 103:17501-17506
40. Saxe MD, Malleret G, Vronskaya S, Mendez I, Garcia AD, Sofroniew MV, Kandel ER, Hen R (2007) Paradoxical influence of hippocampal neurogenesis on working memory. Proc Natl Acad Sci U S A 104:4642-4646
41. Shih TW, Shealy YF, Strother DL, Hill DL (1986) Nonenzymatic isomerization of all-trans- and 13-cis-retinoids catalyzed by sulfhydryl groups. Drug Metab Dispos 14:698-702
42. Sporn MB, Roberts AB, Goodman DS (1994) The retinoids: biology, chemistry, and medicine, 2nd edn. Raven, New York
43. Sundstrom A, Alfredsson L, Sjolin-Forsberg G, Gerden B, Bergman U, Jokinen J (2010) Association of suicide attempts with acne and treatment with isotretinoin: retrospective Swedish cohort study. BMJ 341:c5812
44. Takahashi J, Palmer TD, Gage FH (1999) Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures. J Neurobiol 38:65-81
45. Tsukada M, Schroder M, Roos TC, Chandraratna RA, Reichert U, Merk HF, Orfanos CE, Zouboulis CC (2000) 13-cis Retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans retinoic acid and binding to retinoid acid receptors. J Invest Dermatol 115:321-327
46. Wozel G, Chang A, Zultak M, Czarnetzki BM, Happle R, Barth J, van de Kerkhof PC (1991) The effect of topical retinoids on the leukotriene-B4-induced migration of polymorphonuclear leukocytes into human skin. Arch Dermatol Res 283:158-161