13-Cis retinoic acid exerts its specific activity on human sebocytes through selective intracellular isomerization to all-trans Retinoic acid and binding to retinoid acid receptors

Journal of Investigative Dermatology

Volumn 115, Issue 2, 2000, Pages 321-327

  Tsukada, Miki ^d   Schröder, Mandy ^d   Roos, Thomas C ^a   Chandraratna, Roshantha A S ^b   Reichert, Uwe ^c   Merk, Hans F ^a   Orfanos, Constantin E ^d   Zouboulis, Christos C ^d  

^a UNIVERSITY OF AACHEN MEDICAL CENTER   (Germany)

^b ALLERGAN INC   (United States)

^c Galderma R and D   (France)

^d NONE

Author keywords

Cell line; Isotretinoin; Retinoids; Sebaceous glands

Indexed keywords

4 [2 [5,6 DIHYDRO 5,5 DIMETHYL 8 (4 METHYLPHENYL) 2 NAPHTHYL]ETHYNYL]BENZOIC ACID; ALITRETINOIN; CD 3507; CYTOCHROME P450; ISOTRETINOIN; MESSENGER RNA; RECEPTOR BLOCKING AGENT; RETINOIC ACID; RETINOIC ACID BINDING PROTEIN; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG METABOLISM; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; ISOMERISM; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEBACEOUS GLAND;

EID: 0033870445     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.00066.x     Document Type: Article

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