DNA polymerase eta participates in the mutagenic bypass of adducts induced by benzo[a]pyrene diol epoxide in mammalian cells

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Klarer, Alden C ^a   Stallons, L Jay ^b,c   Burke, Tom J ^b   Skaggs, Robert L ^b,d   McGregor, W Glenn ^a,b  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROXYBENZO[A]PYRENE OXIDE; DNA DIRECTED DNA POLYMERASE ETA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

ANIMAL CELL; ARTICLE; CHEMICAL MUTAGENESIS; CONTROLLED STUDY; CYTOTOXICITY; DNA ADDUCT; EMBRYO; ENZYME ACTIVITY; ENZYME DEFICIENCY; FIBROBLAST; GENE; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; HYPOXANTHINE GUANINE PHOSPHORIBOSYLTRANSFERASE GENE; IN VITRO STUDY; MAMMAL CELL; MOUSE; MUTATION RATE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; CELLS, CULTURED; DNA ADDUCTS; DNA-DIRECTED DNA POLYMERASE; FIBROBLASTS; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 84862659858     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039596     Document Type: Article

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