-
1
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal, A., Siegel, R., Xu, J., and Ward, E. (2010) Cancer statistics, 2010. CA Cancer J. Clin. 60, 277-300.
-
(2010)
CA Cancer J. Clin.
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
2
-
-
2942592008
-
Dual kinase inhibition in the treatment of breast cancer: Initial experience with the EGFR/ErbB-2 inhibitor lapatinib
-
Burris, H. A., 3rd. (2004) Dual kinase inhibition in the treatment of breast cancer: initial experience with the EGFR/ErbB-2 inhibitor lapatinib. Oncologist 9 (Suppl 3), 10-5.
-
(2004)
Oncologist
, vol.9
, Issue.SUPPL. 3
, pp. 10-15
-
-
Burris III, H.A.1
-
3
-
-
33845886440
-
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
-
Geyer, C. E., Forster, J., Lindquist, D., Chan, S., Romieu, C. G., Pienkowski, T., Jagiello-Gruszfeld, A., Crown, J., Chan, A., Kaufman, B., Skarlos, D., Campone, M., Davidson, N., Berger, M., Oliva, C., Rubin, S. D., Stein, S., and Cameron, D. (2006) Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N. Engl. J. Med. 355, 2733-43.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
Chan, S.4
Romieu, C.G.5
Pienkowski, T.6
Jagiello-Gruszfeld, A.7
Crown, J.8
Chan, A.9
Kaufman, B.10
Skarlos, D.11
Campone, M.12
Davidson, N.13
Berger, M.14
Oliva, C.15
Rubin, S.D.16
Stein, S.17
Cameron, D.18
-
4
-
-
19944427176
-
Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells
-
Jones, H. E., Goddard, L., Gee, J. M., Hiscox, S., Rubini, M., Barrow, D., Knowlden, J. M., Williams, S., Wakeling, A. E., and Nicholson, R. I. (2004) Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells. Endocr. Relat. Cancer 11, 793-814.
-
(2004)
Endocr. Relat. Cancer
, vol.11
, pp. 793-814
-
-
Jones, H.E.1
Goddard, L.2
Gee, J.M.3
Hiscox, S.4
Rubini, M.5
Barrow, D.6
Knowlden, J.M.7
Williams, S.8
Wakeling, A.E.9
Nicholson, R.I.10
-
5
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem, E., Kohne, C. H., Hitre, E., Zaluski, J., Chang Chien, C. R., Makhson, A., D'Haens, G., Pinter, T., Lim, R., Bodoky, G., Roh, J. K., Folprecht, G., Ruff, P., Stroh, C., Tejpar, S., Schlichting, M., Nippgen, J., and Rougier, P. (2009) Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N. Engl. J. Med. 360, 1408-17.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
Kohne, C.H.2
Hitre, E.3
Zaluski, J.4
Chang Chien, C.R.5
Makhson, A.6
D'Haens, G.7
Pinter, T.8
Lim, R.9
Bodoky, G.10
Roh, J.K.11
Folprecht, G.12
Ruff, P.13
Stroh, C.14
Tejpar, S.15
Schlichting, M.16
Nippgen, J.17
Rougier, P.18
-
6
-
-
34547744955
-
Assessment of 11C-labeled-4-N-(3-bromoanilino)-6,7-dimethoxyquinazoline as a positron emission tomography agent to monitor epidermal growth factor receptor expression
-
Wang, H., Yu, J., Yang, G., Song, X., Sun, X., Zhao, S., and Mu, D. (2007) Assessment of 11C-labeled-4-N-(3-bromoanilino)-6,7-dimethoxyquinazoline as a positron emission tomography agent to monitor epidermal growth factor receptor expression. Cancer Sci. 98, 1413-6.
-
(2007)
Cancer Sci.
, vol.98
, pp. 1413-1416
-
-
Wang, H.1
Yu, J.2
Yang, G.3
Song, X.4
Sun, X.5
Zhao, S.6
Mu, D.7
-
7
-
-
43749125020
-
Evaluation of [(18)F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors
-
Su, H., Seimbille, Y., Ferl, G. Z., Bodenstein, C., Fueger, B., Kim, K. J., Hsu, Y. T., Dubinett, S. M., Phelps, M. E., Czernin, J., and Weber, W. A. (2008) Evaluation of [(18)F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors. Eur. J. Nucl. Med. Mol. Imaging 35, 1089-99.
-
(2008)
Eur. J. Nucl. Med. Mol. Imaging
, vol.35
, pp. 1089-1099
-
-
Su, H.1
Seimbille, Y.2
Ferl, G.Z.3
Bodenstein, C.4
Fueger, B.5
Kim, K.J.6
Hsu, Y.T.7
Dubinett, S.M.8
Phelps, M.E.9
Czernin, J.10
Weber, W.A.11
-
8
-
-
29344448254
-
A new generation of protein display scaffolds for molecular recognition
-
Hosse, R. J., Rothe, A., and Power, B. E. (2006) A new generation of protein display scaffolds for molecular recognition. Protein Sci. 15, 14-27.
-
(2006)
Protein Sci.
, vol.15
, pp. 14-27
-
-
Hosse, R.J.1
Rothe, A.2
Power, B.E.3
-
9
-
-
27144511241
-
Engineering novel binding proteins from nonimmunoglobulin domains
-
Binz, H. K., Amstutz, P., and Pluckthun, A. (2005) Engineering novel binding proteins from nonimmunoglobulin domains. Nat. Biotechnol. 23, 1257-68.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1257-1268
-
-
Binz, H.K.1
Amstutz, P.2
Pluckthun, A.3
-
10
-
-
77953130101
-
Affibody molecules: Engineered proteins for therapeutic, diagnostic and biotechnological applications
-
Lofblom, J., Feldwisch, J., Tolmachev, V., Carlsson, J., Stahl, S., and Frejd, F. Y. (2010) Affibody molecules: engineered proteins for therapeutic, diagnostic and biotechnological applications. FEBS Lett. 584, 2670-80.
-
(2010)
FEBS Lett.
, vol.584
, pp. 2670-2680
-
-
Lofblom, J.1
Feldwisch, J.2
Tolmachev, V.3
Carlsson, J.4
Stahl, S.5
Frejd, F.Y.6
-
11
-
-
33947318463
-
Affibody molecules: New protein domains for molecular imaging and targeted tumor therapy
-
Nilsson, F. Y., and Tolmachev, V. (2007) Affibody molecules: new protein domains for molecular imaging and targeted tumor therapy. Curr. Opin. Drug Discovery Dev. 10, 167-75.
-
(2007)
Curr. Opin. Drug Discovery Dev.
, vol.10
, pp. 167-175
-
-
Nilsson, F.Y.1
Tolmachev, V.2
-
12
-
-
34047155118
-
Affibody molecules: Potential for in vivo imaging of molecular targets for cancer therapy
-
Tolmachev, V., Orlova, A., Nilsson, F. Y., Feldwisch, J., Wennborg, A., and Abrahmsen, L. (2007) Affibody molecules: potential for in vivo imaging of molecular targets for cancer therapy. Expert Opin. Biol. Ther. 7, 555-68.
-
(2007)
Expert Opin. Biol. Ther.
, vol.7
, pp. 555-568
-
-
Tolmachev, V.1
Orlova, A.2
Nilsson, F.Y.3
Feldwisch, J.4
Wennborg, A.5
Abrahmsen, L.6
-
13
-
-
84855223865
-
Protein scaffold-based molecular probes for cancer molecular imaging
-
Miao, Z., Levi, J., and Cheng, Z. (2010) Protein scaffold-based molecular probes for cancer molecular imaging. Amino Acids,.
-
(2010)
Amino Acids
-
-
Miao, Z.1
Levi, J.2
Cheng, Z.3
-
14
-
-
44149108464
-
Small-animal PET imaging of human epidermal growth factor receptor type 2 expression with site-specific 18F-labeled protein scaffold molecules
-
Cheng, Z., De Jesus, O. P., Namavari, M., De, A., Levi, J., Webster, J. M., Zhang, R., Lee, B., Syud, F. A., and Gambhir, S. S. (2008) Small-animal PET imaging of human epidermal growth factor receptor type 2 expression with site-specific 18F-labeled protein scaffold molecules. J. Nucl. Med. 49, 804-13.
-
(2008)
J. Nucl. Med.
, vol.49
, pp. 804-813
-
-
Cheng, Z.1
De Jesus, O.P.2
Namavari, M.3
De, A.4
Levi, J.5
Webster, J.M.6
Zhang, R.7
Lee, B.8
Syud, F.A.9
Gambhir, S.S.10
-
15
-
-
52449108735
-
Affibody molecules for in vivo characterization of HER2-positive tumors by near-infrared imaging
-
Lee, S. B., Hassan, M., Fisher, R., Chertov, O., Chernomordik, V., Kramer-Marek, G., Gandjbakhche, A., and Capala, J. (2008) Affibody molecules for in vivo characterization of HER2-positive tumors by near-infrared imaging. Clin. Cancer Res. 14, 3840-9.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3840-3849
-
-
Lee, S.B.1
Hassan, M.2
Fisher, R.3
Chertov, O.4
Chernomordik, V.5
Kramer-Marek, G.6
Gandjbakhche, A.7
Capala, J.8
-
16
-
-
84855215798
-
Protein scaffold-based molecular probes for cancer molecular imaging
-
Miao, Z., Levi, J., and Cheng, Z. (2011) Protein scaffold-based molecular probes for cancer molecular imaging. Amino Acids 41, 1037-47.
-
(2011)
Amino Acids
, vol.41
, pp. 1037-1047
-
-
Miao, Z.1
Levi, J.2
Cheng, Z.3
-
17
-
-
79952313111
-
Engineered high-affinity affibody molecules targeting platelet-derived growth factor receptor beta in vivo
-
Lindborg, M., Cortez, E., Hoiden-Guthenberg, I., Gunneriusson, E., von Hage, E., Syud, F., Morrison, M., Abrahmsen, L., Herne, N., Pietras, K., and Frejd, F. Y. (2011) Engineered high-affinity affibody molecules targeting platelet-derived growth factor receptor beta in vivo. J. Mol. Biol. 407, 298-315.
-
(2011)
J. Mol. Biol.
, vol.407
, pp. 298-315
-
-
Lindborg, M.1
Cortez, E.2
Hoiden-Guthenberg, I.3
Gunneriusson, E.4
Von Hage, E.5
Syud, F.6
Morrison, M.7
Abrahmsen, L.8
Herne, N.9
Pietras, K.10
Frejd, F.Y.11
-
18
-
-
39149087035
-
Directed evolution to low nanomolar affinity of a tumor-targeting epidermal growth factor receptor-binding affibody molecule
-
Friedman, M., Orlova, A., Johansson, E., Eriksson, T. L., Hoiden-Guthenberg, I., Tolmachev, V., Nilsson, F. Y., and Stahl, S. (2008) Directed evolution to low nanomolar affinity of a tumor-targeting epidermal growth factor receptor-binding affibody molecule. J. Mol. Biol. 376, 1388-402.
-
(2008)
J. Mol. Biol.
, vol.376
, pp. 1388-1402
-
-
Friedman, M.1
Orlova, A.2
Johansson, E.3
Eriksson, T.L.4
Hoiden-Guthenberg, I.5
Tolmachev, V.6
Nilsson, F.Y.7
Stahl, S.8
-
19
-
-
77952565937
-
Small-animal PET imaging of human epidermal growth factor receptor positive tumor with a 64Cu labeled affibody protein
-
Miao, Z., Ren, G., Liu, H., Jiang, L., and Cheng, Z. (2010) Small-animal PET imaging of human epidermal growth factor receptor positive tumor with a 64Cu labeled affibody protein. Bioconjugate Chem. 21, 947-54.
-
(2010)
Bioconjugate Chem.
, vol.21
, pp. 947-954
-
-
Miao, Z.1
Ren, G.2
Liu, H.3
Jiang, L.4
Cheng, Z.5
-
20
-
-
78651462095
-
Cy5.5-labeled Affibody molecule for near-infrared fluorescent optical imaging of epidermal growth factor receptor positive tumors
-
Miao, Z., Ren, G., Liu, H., Jiang, L., and Cheng, Z. (2010) Cy5.5-labeled Affibody molecule for near-infrared fluorescent optical imaging of epidermal growth factor receptor positive tumors. J. Biomed. Opt. 15, 036007.
-
(2010)
J. Biomed. Opt.
, vol.15
, pp. 036007
-
-
Miao, Z.1
Ren, G.2
Liu, H.3
Jiang, L.4
Cheng, Z.5
-
21
-
-
4644325597
-
Comparative biodistribution of potential anti-glioblastoma conjugates [111In]DTPA-hEGF and [111In]Bz-DTPA-hEGF in normal mice
-
Tolmachev, V., Orlova, A., Wei, Q., Bruskin, A., Carlsson, J., and Gedda, L. (2004) Comparative biodistribution of potential anti-glioblastoma conjugates [111In]DTPA-hEGF and [111In]Bz-DTPA-hEGF in normal mice. Cancer Biother. Radiopharm. 19, 491-501.
-
(2004)
Cancer Biother. Radiopharm.
, vol.19
, pp. 491-501
-
-
Tolmachev, V.1
Orlova, A.2
Wei, Q.3
Bruskin, A.4
Carlsson, J.5
Gedda, L.6
-
22
-
-
34547202931
-
Squaraine rotaxanes: Superior substitutes for Cy-5 in molecular probes for near-infrared fluorescence cell imaging
-
Johnson, J. R., Fu, N., Arunkumar, E., Leevy, W. M., Gammon, S. T., Piwnica-Worms, D., and Smith, B. D. (2007) Squaraine rotaxanes: superior substitutes for Cy-5 in molecular probes for near-infrared fluorescence cell imaging. Angew. Chem., Int. Ed. Engl. 46, 5528-31.
-
(2007)
Angew. Chem., Int. Ed. Engl.
, vol.46
, pp. 5528-5531
-
-
Johnson, J.R.1
Fu, N.2
Arunkumar, E.3
Leevy, W.M.4
Gammon, S.T.5
Piwnica-Worms, D.6
Smith, B.D.7
-
23
-
-
33745125089
-
Squaraine-derived rotaxanes: Highly stable, fluorescent near-IR dyes
-
Arunkumar, E., Fu, N., and Smith, B. D. (2006) Squaraine-derived rotaxanes: highly stable, fluorescent near-IR dyes. Chemistry 12, 4684-90.
-
(2006)
Chemistry
, vol.12
, pp. 4684-4690
-
-
Arunkumar, E.1
Fu, N.2
Smith, B.D.3
-
24
-
-
14944373224
-
Squaraine-derived rotaxanes: Sterically protected fluorescent near-IR dyes
-
Arunkumar, E., Forbes, C. C., Noll, B. C., and Smith, B. D. (2005) Squaraine-derived rotaxanes: sterically protected fluorescent near-IR dyes. J. Am. Chem. Soc. 127, 3288-9.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 3288-3289
-
-
Arunkumar, E.1
Forbes, C.C.2
Noll, B.C.3
Smith, B.D.4
-
25
-
-
3042541034
-
Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models
-
Troy, T., Jekic-McMullen, D., Sambucetti, L., and Rice, B. (2004) Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models. Mol. Imaging 3, 9-23.
-
(2004)
Mol. Imaging
, vol.3
, pp. 9-23
-
-
Troy, T.1
Jekic-McMullen, D.2
Sambucetti, L.3
Rice, B.4
-
26
-
-
27944452698
-
Near-infrared fluorescent RGD peptides for optical imaging of integrin alphavbeta3 expression in living mice
-
Cheng, Z., Wu, Y., Xiong, Z., Gambhir, S. S., and Chen, X. (2005) Near-infrared fluorescent RGD peptides for optical imaging of integrin alphavbeta3 expression in living mice. Bioconjugate Chem. 16, 1433-41.
-
(2005)
Bioconjugate Chem.
, vol.16
, pp. 1433-1441
-
-
Cheng, Z.1
Wu, Y.2
Xiong, Z.3
Gambhir, S.S.4
Chen, X.5
-
27
-
-
39049125272
-
Assessment of bevacizumab conjugated to Cy5.5 for detection of head and neck cancer xenografts
-
Withrow, K. P., Newman, J. R., Skipper, J. B., Gleysteen, J. P., Magnuson, J. S., Zinn, K., and Rosenthal, E. L. (2008) Assessment of bevacizumab conjugated to Cy5.5 for detection of head and neck cancer xenografts. Technol. Cancer Res. Treat. 7, 61-6.
-
(2008)
Technol. Cancer Res. Treat.
, vol.7
, pp. 61-66
-
-
Withrow, K.P.1
Newman, J.R.2
Skipper, J.B.3
Gleysteen, J.P.4
Magnuson, J.S.5
Zinn, K.6
Rosenthal, E.L.7
-
28
-
-
73149096993
-
Characterizing breast cancer xenograft epidermal growth factor receptor expression by using near-infrared optical imaging
-
Wang, K., Li, W., Huang, T., Li, R., Wang, D., Shen, B., and Chen, X. (2009) Characterizing breast cancer xenograft epidermal growth factor receptor expression by using near-infrared optical imaging. Acta Radiol. 50, 1095-103.
-
(2009)
Acta Radiol.
, vol.50
, pp. 1095-1103
-
-
Wang, K.1
Li, W.2
Huang, T.3
Li, R.4
Wang, D.5
Shen, B.6
Chen, X.7
-
29
-
-
34250673905
-
Comparison of visible and near-infrared wavelength-excitable fluorescent dyes for molecular imaging of cancer
-
Adams, K. E., Ke, S., Kwon, S., Liang, F., Fan, Z., Lu, Y., Hirschi, K., Mawad, M. E., Barry, M. A., and Sevick-Muraca, E. M. (2007) Comparison of visible and near-infrared wavelength-excitable fluorescent dyes for molecular imaging of cancer. J. Biomed. Opt. 12, 024017.
-
(2007)
J. Biomed. Opt.
, vol.12
, pp. 024017
-
-
Adams, K.E.1
Ke, S.2
Kwon, S.3
Liang, F.4
Fan, Z.5
Lu, Y.6
Hirschi, K.7
Mawad, M.E.8
Barry, M.A.9
Sevick-Muraca, E.M.10
-
30
-
-
0030049664
-
Radiolocalization of squamous lung carcinoma with 131I-labeled epidermal growth factor
-
Cuartero-Plaza, A., Martinez-Miralles, E., Rosell, R., Vadell-Nadal, C., Farre, M., and Real, F. X. (1996) Radiolocalization of squamous lung carcinoma with 131I-labeled epidermal growth factor. Clin. Cancer Res. 2, 13-20.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 13-20
-
-
Cuartero-Plaza, A.1
Martinez-Miralles, E.2
Rosell, R.3
Vadell-Nadal, C.4
Farre, M.5
Real, F.X.6
-
31
-
-
38949102704
-
Imaging epidermal growth factor receptor expression in vivo: Pharmacokinetic and biodistribution characterization of a bioconjugated quantum dot nanoprobe
-
Diagaradjane, P., Orenstein-Cardona, J. M., Colon-Casasnovas, N. E., Deorukhkar, A., Shentu, S., Kuno, N., Schwartz, D. L., Gelovani, J. G., and Krishnan, S. (2008) Imaging epidermal growth factor receptor expression in vivo: pharmacokinetic and biodistribution characterization of a bioconjugated quantum dot nanoprobe. Clin. Cancer Res. 14, 731-41.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 731-741
-
-
Diagaradjane, P.1
Orenstein-Cardona, J.M.2
Colon-Casasnovas, N.E.3
Deorukhkar, A.4
Shentu, S.5
Kuno, N.6
Schwartz, D.L.7
Gelovani, J.G.8
Krishnan, S.9
-
32
-
-
76649094603
-
HER2- and EGFR-specific affiprobes: Novel recombinant optical probes for cell imaging
-
Lyakhov, I., Zielinski, R., Kuban, M., Kramer-Marek, G., Fisher, R., Chertov, O., Bindu, L., and Capala, J. (2010) HER2- and EGFR-specific affiprobes: novel recombinant optical probes for cell imaging. ChemBioChem 11, 345-50.
-
(2010)
ChemBioChem
, vol.11
, pp. 345-350
-
-
Lyakhov, I.1
Zielinski, R.2
Kuban, M.3
Kramer-Marek, G.4
Fisher, R.5
Chertov, O.6
Bindu, L.7
Capala, J.8
-
33
-
-
76749085636
-
In vivo imaging of xenograft tumors using an epidermal growth factor receptor-specific affibody molecule labeled with a near-infrared fluorophore
-
Gong, H., Kovar, J., Little, G., Chen, H., and Olive, D. M. (2010) In vivo imaging of xenograft tumors using an epidermal growth factor receptor-specific affibody molecule labeled with a near-infrared fluorophore. Neoplasia 12, 139-49.
-
(2010)
Neoplasia
, vol.12
, pp. 139-149
-
-
Gong, H.1
Kovar, J.2
Little, G.3
Chen, H.4
Olive, D.M.5
|