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Volumn 29, Issue 6, 2012, Pages 1444-1453

Use of artificial digestive systems to investigate the biopharmaceutical factors influencing the survival of probiotic yeast during gastrointestinal transit in humans

Author keywords

biopharmaceutical factors; gastrointestinal models; probiotics; viability

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE; PROBIOTIC AGENT;

EID: 84862643560     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0620-5     Document Type: Article
Times cited : (58)

References (41)
  • 1
    • 0010369584 scopus 로고    scopus 로고
    • Guidelines for the evaluation of probiotics in food
    • Food and Agriculture Organization of the United Nations - World Health Organization Working group. April 30 and May 1
    • Food and Agriculture Organization of the United Nations - World Health Organization Working group. Guidelines for the evaluation of probiotics in food. Report of a joint FAO/WHO working group on drafting guidelines for the evaluation of probiotics in food.; 2002 April 30 and May 1. Available from: http://www.who.int/foodsafety/fs-management/en/probiotic-guidelines.pdf
    • (2002) Report of A Joint FAO/WHO Working Group on Drafting Guidelines for the Evaluation of Probiotics in Food
  • 2
    • 77949619014 scopus 로고    scopus 로고
    • Probiotics
    • 20208051 10.2146/ajhp090168 1:CAS:528:DC%2BC3cXkvVOnu74%3D
    • NT Williams 2010 Probiotics Am J Health Syst Pharm. 67 6 449 458 20208051 10.2146/ajhp090168 1:CAS:528:DC%2BC3cXkvVOnu74%3D
    • (2010) Am J Health Syst Pharm. , vol.67 , Issue.6 , pp. 449-458
    • Williams, N.T.1
  • 3
    • 77952615260 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of Saccharomyces boulardii in adult patients
    • 20458757 10.3748/wjg.v16.i18.2202
    • LV McFarland 2010 Systematic review and meta-analysis of Saccharomyces boulardii in adult patients World J Gastroenterol. 16 18 2202 2222 20458757 10.3748/wjg.v16.i18.2202
    • (2010) World J Gastroenterol. , vol.16 , Issue.18 , pp. 2202-2222
    • McFarland, L.V.1
  • 4
    • 33847685870 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae strain 905 reduces the translocation of Salmonella enterica serotype Typhimurium and stimulates the immune system in gnotobiotic and conventional mice
    • 10.1099/jmm.0.46525-0
    • FS Martin AC Rodrigues FC Tiago FJ Penna CA Rosa RM Arantes, et al. 2007 Saccharomyces cerevisiae strain 905 reduces the translocation of Salmonella enterica serotype Typhimurium and stimulates the immune system in gnotobiotic and conventional mice J Med Microbiol. 56 352 359 10.1099/jmm.0.46525-0
    • (2007) J Med Microbiol. , vol.56 , pp. 352-359
    • Martin, F.S.1    Rodrigues, A.C.2    Tiago, F.C.3    Penna, F.J.4    Rosa, C.A.5    Arantes, R.M.6
  • 5
    • 77952486696 scopus 로고    scopus 로고
    • Probiotic yeasts: Anti-inflammatory potentential of various non-pathogenic strains in experimental colitis in mice
    • 20440854 10.3748/wjg.v16.i17.2134
    • B Foligné J Dewulf P Vandekerckove G Pignède B Pot 2010 Probiotic yeasts: Anti-inflammatory potentential of various non-pathogenic strains in experimental colitis in mice World J Gastroenterol. 16 17 2134 2145 20440854 10.3748/wjg.v16.i17.2134
    • (2010) World J Gastroenterol. , vol.16 , Issue.17 , pp. 2134-2145
    • Foligné, B.1    Dewulf, J.2    Vandekerckove, P.3    Pignède, G.4    Pot, B.5
  • 6
    • 79551496197 scopus 로고    scopus 로고
    • Effect of a new probiotic Saccharomyces cerevisiae strain on the survival of Escherichia coli O157:H7 in a dynamic gastrointestinal model
    • 21131521 10.1128/AEM.02130-10 1:CAS:528:DC%2BC3MXisVOqs74%3D
    • L Etienne-Mesmin V Livrelli M Privat S Denis JM Cardot M Alric, et al. 2011 Effect of a new probiotic Saccharomyces cerevisiae strain on the survival of Escherichia coli O157:H7 in a dynamic gastrointestinal model Appl Environ Microbiol. 77 3 1127 1131 21131521 10.1128/AEM.02130-10 1:CAS:528: DC%2BC3MXisVOqs74%3D
    • (2011) Appl Environ Microbiol. , vol.77 , Issue.3 , pp. 1127-1131
    • Etienne-Mesmin, L.1    Livrelli, V.2    Privat, M.3    Denis, S.4    Cardot, J.M.5    Alric, M.6
  • 7
    • 84907113494 scopus 로고
    • Dose response on the faecal colonisation of Lactobacillus strain GG administered in two different formulations
    • 10.3109/08910609309141315
    • M Saxelin M Ahokas S Salminen 1993 Dose response on the faecal colonisation of Lactobacillus strain GG administered in two different formulations Microb Ecol Health Dis. 6 119 122 10.3109/08910609309141315
    • (1993) Microb Ecol Health Dis. , vol.6 , pp. 119-122
    • Saxelin, M.1    Ahokas, M.2    Salminen, S.3
  • 8
    • 33646453352 scopus 로고    scopus 로고
    • The survival and persistence in the human gastrointestinal tract of five potential probiotic lactobacilli consumed as freeze-dried cultures or as probiotic sausage
    • 16504324 10.1016/j.ijfoodmicro.2006.01.014
    • TD Klingberg B Bjǿrn Budde 2006 The survival and persistence in the human gastrointestinal tract of five potential probiotic lactobacilli consumed as freeze-dried cultures or as probiotic sausage Int J Food Microbiol 109 157 159 16504324 10.1016/j.ijfoodmicro.2006.01.014
    • (2006) Int J Food Microbiol , vol.109 , pp. 157-159
    • Klingberg, T.D.1    Bjǿrn Budde, B.2
  • 9
    • 77953536656 scopus 로고    scopus 로고
    • Bacteria and chocolate: A successful combination for probiotic delivery
    • 20452073 10.1016/j.ijfoodmicro.2010.03.008 1:CAS:528:DC%2BC3cXntVeksLg%3D
    • S Possemiers M Marzorati W Verstraete T Vande Wiele 2010 Bacteria and chocolate: a successful combination for probiotic delivery Int J Food Microbiol 141 97 103 20452073 10.1016/j.ijfoodmicro.2010.03.008 1:CAS:528: DC%2BC3cXntVeksLg%3D
    • (2010) Int J Food Microbiol , vol.141 , pp. 97-103
    • Possemiers, S.1    Marzorati, M.2    Verstraete, W.3    Vande Wiele, T.4
  • 10
    • 30844470928 scopus 로고    scopus 로고
    • Microentrapment of probiotic bacteria in a Ca2+-induced whey protein gel and effects on their viability in a dynamic gastro-intestinal model
    • 16401577 10.1080/02652040500162840 1:CAS:528:DC%2BD28Xks1Wisg%3D%3D
    • A Ainsley Reid JC Vuillemard M Britten Y Arcand E Farnworth CP Champagne 2005 Microentrapment of probiotic bacteria in a Ca2+-induced whey protein gel and effects on their viability in a dynamic gastro-intestinal model J Microencapsul 22 6 603 619 16401577 10.1080/02652040500162840 1:CAS:528:DC%2BD28Xks1Wisg%3D%3D
    • (2005) J Microencapsul , vol.22 , Issue.6 , pp. 603-619
    • Ainsley Reid, A.1    Vuillemard, J.C.2    Britten, M.3    Arcand, Y.4    Farnworth, E.5    Champagne, C.P.6
  • 11
    • 38849083178 scopus 로고    scopus 로고
    • Formulations for protecting the probiotic Saccharomyces boulardii from degradation in acidic condition
    • 18239285 10.1248/bpb.31.266 1:CAS:528:DC%2BD1cXmtlaks7k%3D
    • S Graff JC Chaumeil P Boy R Lai-Kuen C Charrueau 2008 Formulations for protecting the probiotic Saccharomyces boulardii from degradation in acidic condition Biol Pharm Bull. 31 2 266 272 18239285 10.1248/bpb.31.266 1:CAS:528:DC%2BD1cXmtlaks7k%3D
    • (2008) Biol Pharm Bull. , vol.31 , Issue.2 , pp. 266-272
    • Graff, S.1    Chaumeil, J.C.2    Boy, P.3    Lai-Kuen, R.4    Charrueau, C.5
  • 12
    • 61349087293 scopus 로고    scopus 로고
    • Development of tablets containing probiotics: Effects of formulation and processing parameters on bacterial viability
    • 19059323 10.1016/j.ijpharm.2008.11.004 1:CAS:528:DC%2BD1MXislKit7w%3D
    • S Klayraung H Viernstein S Okonogi 2009 Development of tablets containing probiotics: effects of formulation and processing parameters on bacterial viability Int J Pharm. 370 54 60 19059323 10.1016/j.ijpharm.2008.11.004 1:CAS:528:DC%2BD1MXislKit7w%3D
    • (2009) Int J Pharm. , vol.370 , pp. 54-60
    • Klayraung, S.1    Viernstein, H.2    Okonogi, S.3
  • 13
    • 70449469829 scopus 로고    scopus 로고
    • Effects of yeast probiotic formulation on viability, revival and protection against infection with Salmonella enterica spp. enterica serovar Typhimurium in mice
    • 19780950 10.1111/j.1472-765X.2009.02732.x 1:STN:280: DC%2BC3c%2Fjs1SmtQ%3D%3D
    • FS Martins LC Veloso RME Arantes JR Nicoli 2009 Effects of yeast probiotic formulation on viability, revival and protection against infection with Salmonella enterica spp. enterica serovar Typhimurium in mice Lett Appl Microbiol. 49 738 744 19780950 10.1111/j.1472-765X.2009.02732.x 1:STN:280:DC%2BC3c%2Fjs1SmtQ%3D%3D
    • (2009) Lett Appl Microbiol. , vol.49 , pp. 738-744
    • Martins, F.S.1    Veloso, L.C.2    Arantes, R.M.E.3    Nicoli, J.R.4
  • 14
    • 0024320219 scopus 로고
    • Disposition kinetics of Saccharomyces boulardii in man and rat
    • 2758101 10.1002/bdd.2510100403
    • H Bléhaut J Massot GW Elmer RH Levy 1989 Disposition kinetics of Saccharomyces boulardii in man and rat Biopharm Drug Dispos. 10 353 364 2758101 10.1002/bdd.2510100403
    • (1989) Biopharm Drug Dispos. , vol.10 , pp. 353-364
    • Bléhaut, H.1    Massot, J.2    Elmer, G.W.3    Levy, R.H.4
  • 15
    • 0000137063 scopus 로고
    • Dose response colonization of faeces after oral administration of Lactobacillus casei strain GG
    • 10.3109/08910609109140144
    • M Saxelin S Elo S Salminen H Vapaatalo 1991 Dose response colonization of faeces after oral administration of Lactobacillus casei strain GG Microb Ecol Health Dis. 4 209 214 10.3109/08910609109140144
    • (1991) Microb Ecol Health Dis. , vol.4 , pp. 209-214
    • Saxelin, M.1    Elo, S.2    Salminen, S.3    Vapaatalo, H.4
  • 16
    • 0031800841 scopus 로고    scopus 로고
    • Development and application of an in vitro methodology to determine the transit tolerance of potentially probiotic Lactobacillus and Bifidobacterium species in the upper human gastrointestinal tract
    • 9674129 10.1046/j.1365-2672.1998.00407.x 1:CAS:528:DyaK1cXks1aqtbc%3D
    • WP Charteris PM Kelly L Morelli JK Collins 1998 Development and application of an in vitro methodology to determine the transit tolerance of potentially probiotic Lactobacillus and Bifidobacterium species in the upper human gastrointestinal tract J Appl Microbiol. 84 759 768 9674129 10.1046/j.1365-2672.1998.00407.x 1:CAS:528:DyaK1cXks1aqtbc%3D
    • (1998) J Appl Microbiol. , vol.84 , pp. 759-768
    • Charteris, W.P.1    Kelly, P.M.2    Morelli, L.3    Collins, J.K.4
  • 17
    • 77957307906 scopus 로고    scopus 로고
    • Survival of a Lactococcus lactis strain varies with its carbohydrate preference under in vitro conditions simulated gastrointestinal tract
    • 20810182 10.1016/j.ijfoodmicro.2010.07.033 1:CAS:528:DC%2BC3cXht1CmurbI
    • H Kimoto-Nira C Suzuki K Sasaki M Kobayashi K Mizumachi 2010 Survival of a Lactococcus lactis strain varies with its carbohydrate preference under in vitro conditions simulated gastrointestinal tract Int J Food Microbiol. 143 226 229 20810182 10.1016/j.ijfoodmicro.2010.07.033 1:CAS:528:DC%2BC3cXht1CmurbI
    • (2010) Int J Food Microbiol. , vol.143 , pp. 226-229
    • Kimoto-Nira, H.1    Suzuki, C.2    Sasaki, K.3    Kobayashi, M.4    Mizumachi, K.5
  • 18
    • 16244420758 scopus 로고    scopus 로고
    • A dynamic model that simulates the upper gastrointestinal tract for the study of probiotics
    • 15808363 10.1016/j.ijfoodmicro.2004.08.020 1:STN:280: DC%2BD2M7ns1antA%3D%3D
    • I Mainville Y Arcand ER Farnworth 2005 A dynamic model that simulates the upper gastrointestinal tract for the study of probiotics Int J Food Microbiol. 99 287 296 15808363 10.1016/j.ijfoodmicro.2004.08.020 1:STN:280: DC%2BD2M7ns1antA%3D%3D
    • (2005) Int J Food Microbiol. , vol.99 , pp. 287-296
    • Mainville, I.1    Arcand, Y.2    Farnworth, E.R.3
  • 19
    • 48349138946 scopus 로고    scopus 로고
    • Single bioreactor gastrointestinal tract simulator for study of survival of probiotic bacteria
    • 18581109 10.1007/s00253-008-1553-8 1:CAS:528:DC%2BD1cXptVeqt7Y%3D
    • I Sumeri L Arike K Adamberg T Paalme 2008 Single bioreactor gastrointestinal tract simulator for study of survival of probiotic bacteria Appl Microbiol Biotechnol. 80 317 324 18581109 10.1007/s00253-008-1553-8 1:CAS:528:DC%2BD1cXptVeqt7Y%3D
    • (2008) Appl Microbiol Biotechnol. , vol.80 , pp. 317-324
    • Sumeri, I.1    Arike, L.2    Adamberg, K.3    Paalme, T.4
  • 20
    • 0001151974 scopus 로고
    • Huis in't Veld JHJ. A multicompartmental dynamic computer-controlled model simulating the stomach and small intestine
    • M Minekus P Marteau R Havenaar 1995 Huis in't Veld JHJ. A multicompartmental dynamic computer-controlled model simulating the stomach and small intestine Atla 23 197 209
    • (1995) Atla , vol.23 , pp. 197-209
    • Minekus, M.1    Marteau, P.2    Havenaar, R.3
  • 21
    • 0038220060 scopus 로고    scopus 로고
    • Recombinant Saccharomyces cerevisiae expressing a P450 in artificial digestive systems: A model for bioconversion in human digestive environment
    • 12732562 10.1128/AEM.69.5.2884-2892.2003 1:CAS:528:DC%2BD3sXjslOltrc%3D
    • S Blanquet JP Meunier M Minekus S Marol-Bonnin M Alric 2003 Recombinant Saccharomyces cerevisiae expressing a P450 in artificial digestive systems: a model for bioconversion in human digestive environment Appl Environ Microbiol. 69 2884 2892 12732562 10.1128/AEM.69.5.2884-2892.2003 1:CAS:528: DC%2BD3sXjslOltrc%3D
    • (2003) Appl Environ Microbiol. , vol.69 , pp. 2884-2892
    • Blanquet, S.1    Meunier, J.P.2    Minekus, M.3    Marol-Bonnin, S.4    Alric, M.5
  • 22
    • 28444435904 scopus 로고    scopus 로고
    • A level A in vitro/in vivo correlation in fasted and fed states using different methods: Applied to solid immediate release oral dosage form
    • 16169713 10.1016/j.ejps.2005.08.006 1:CAS:528:DC%2BD2MXht1OntLfF
    • S Souliman S Blanquet Beyssac JM Cardot 2006 A level A in vitro/in vivo correlation in fasted and fed states using different methods: applied to solid immediate release oral dosage form Eur J Pharm Sci 27 72 79 16169713 10.1016/j.ejps.2005.08.006 1:CAS:528:DC%2BD2MXht1OntLfF
    • (2006) Eur J Pharm Sci , vol.27 , pp. 72-79
    • Souliman, S.1    Blanquet, S.2    Beyssac3    Cardot, J.M.4
  • 23
    • 0031158713 scopus 로고    scopus 로고
    • Survival of lactic acid bacteria in a dynamic model of the stomach and small intestine: Validation and the effects of bile
    • 9201571 10.3168/jds.S0022-0302(97)76027-2 1:CAS:528:DyaK2sXjvFWhtr8%3D
    • P Marteau M Minekus R Havenaar JHJ Huis In't Veld 1997 Survival of lactic acid bacteria in a dynamic model of the stomach and small intestine: validation and the effects of bile J Dairy Sci. 80 1031 1037 9201571 10.3168/jds.S0022- 0302(97)76027-2 1:CAS:528:DyaK2sXjvFWhtr8%3D
    • (1997) J Dairy Sci. , vol.80 , pp. 1031-1037
    • Marteau, P.1    Minekus, M.2    Havenaar, R.3    Huis In't Veld, J.H.J.4
  • 24
    • 1842450785 scopus 로고    scopus 로고
    • A dynamic gastrointestinal system for studying the behavior of orally administered drug dosage forms under various physiological conditions
    • 15139514 10.1023/B:PHAM.0000022404.70478.4b 1:CAS:528: DC%2BD2cXjsVWqsLo%3D
    • S Blanquet E Zeijdner E Beyssac JP Meunier S Denis R Havenaar, et al. 2004 A dynamic gastrointestinal system for studying the behavior of orally administered drug dosage forms under various physiological conditions Pharm Res. 21 585 591 15139514 10.1023/B:PHAM.0000022404.70478.4b 1:CAS:528: DC%2BD2cXjsVWqsLo%3D
    • (2004) Pharm Res. , vol.21 , pp. 585-591
    • Blanquet, S.1    Zeijdner, E.2    Beyssac, E.3    Meunier, J.P.4    Denis, S.5    Havenaar, R.6
  • 25
    • 0030907922 scopus 로고    scopus 로고
    • Investigations of bifidobacterial ecology and oligosaccharide metabolism in a three-stage compound continuous culture system
    • 9145444 1:STN:280:DyaK2s3ptVOqug%3D%3D
    • AJ McBain GT Macfarlane 1997 Investigations of bifidobacterial ecology and oligosaccharide metabolism in a three-stage compound continuous culture system Scand J Gastroenterol Suppl. 222 32 40 9145444 1:STN:280: DyaK2s3ptVOqug%3D%3D
    • (1997) Scand J Gastroenterol Suppl. , vol.222 , pp. 32-40
    • McBain, A.J.1    Macfarlane, G.T.2
  • 26
    • 0033547717 scopus 로고    scopus 로고
    • The effect of probiotic strains on the microbiota of the simulator of the human intestinal microbial ecosystem (SHIME)
    • 10050686 10.1016/S0168-1605(98)00182-2 1:STN:280:DyaK1M7lsl2ksQ%3D%3D
    • M Alander I De Smet L Nollet W Verstraete A Von Wright T Mattila-Sandholm 1999 The effect of probiotic strains on the microbiota of the simulator of the human intestinal microbial ecosystem (SHIME) Int J Food Microbiol. 46 71 79 10050686 10.1016/S0168-1605(98)00182-2 1:STN:280:DyaK1M7lsl2ksQ%3D%3D
    • (1999) Int J Food Microbiol. , vol.46 , pp. 71-79
    • Alander, M.1    De Smet, I.2    Nollet, L.3    Verstraete, W.4    Von Wright, A.5    Mattila-Sandholm, T.6
  • 27
    • 36849039423 scopus 로고    scopus 로고
    • Glycerol induces reuterin production and decreases Escherichia coli population in an in vitro model of colonic fermentation with immobilized human feces
    • 18028400 10.1111/j.1574-6941.2007.00412.x 1:CAS:528:DC%2BD1cXhvVOnu74%3D
    • V Cleusix C Lacroix S Vollenweider G Le Blay 2008 Glycerol induces reuterin production and decreases Escherichia coli population in an in vitro model of colonic fermentation with immobilized human feces FEMS Microbiol Ecol. 63 56 64 18028400 10.1111/j.1574-6941.2007.00412.x 1:CAS:528: DC%2BD1cXhvVOnu74%3D
    • (2008) FEMS Microbiol Ecol. , vol.63 , pp. 56-64
    • Cleusix, V.1    Lacroix, C.2    Vollenweider, S.3    Le Blay, G.4
  • 28
    • 77955956987 scopus 로고    scopus 로고
    • Development and validation of a continuous in vitro system reproducing some biotic and abiotic factors of the veal calf intestine
    • 20581176 10.1128/AEM.00524-10
    • M Gérard-Champod S Blanquet-Diot JM Cardot D Bravo M Alric 2010 Development and validation of a continuous in vitro system reproducing some biotic and abiotic factors of the veal calf intestine Appl Environ Microbiol. 76 5592 5600 20581176 10.1128/AEM.00524-10
    • (2010) Appl Environ Microbiol. , vol.76 , pp. 5592-5600
    • Gérard-Champod, M.1    Blanquet-Diot, S.2    Cardot, J.M.3    Bravo, D.4    Alric, M.5
  • 29
    • 0033429431 scopus 로고    scopus 로고
    • Behaviour of Saccharomyces boulardii in recurrent Clostridium difficile disease patients
    • 10594402 10.1046/j.1365-2036.1999.00666.x 1:STN:280: DC%2BD3c%2Fmt1ektQ%3D%3D
    • GW Elmer LV McFarland CM Surawicz L Danko RN Greenberg 1999 Behaviour of Saccharomyces boulardii in recurrent Clostridium difficile disease patients Aliment Pharmacol Ther. 13 12 1663 1668 10594402 10.1046/j.1365-2036.1999.00666. x 1:STN:280:DC%2BD3c%2Fmt1ektQ%3D%3D
    • (1999) Aliment Pharmacol Ther. , vol.13 , Issue.12 , pp. 1663-1668
    • Elmer, G.W.1    McFarland, L.V.2    Surawicz, C.M.3    Danko, L.4    Greenberg, R.N.5
  • 30
    • 0037380284 scopus 로고    scopus 로고
    • Dose-response relationship and mechanism of action of Saccharomyces boulardii in castor oil-induced diarrhea in rats
    • 12741470 10.1023/A:1022801228938 1:CAS:528:DC%2BD3sXitFegs7c%3D
    • P Girard Y Pansart I Lorette JM Gillardin 2003 Dose-response relationship and mechanism of action of Saccharomyces boulardii in castor oil-induced diarrhea in rats Dig Dis Sci. 48 4 770 774 12741470 10.1023/A:1022801228938 1:CAS:528:DC%2BD3sXitFegs7c%3D
    • (2003) Dig Dis Sci. , vol.48 , Issue.4 , pp. 770-774
    • Girard, P.1    Pansart, Y.2    Lorette, I.3    Gillardin, J.M.4
  • 31
    • 0020379121 scopus 로고
    • Analysis of gastric emptying data
    • 7129034 1:STN:280:DyaL3s%2FivVCjsQ%3D%3D
    • JD Elashoff TJ Reedy JH Meyer 1982 Analysis of gastric emptying data Gastroenterology. 83 6 1306 1312 7129034 1:STN:280:DyaL3s%2FivVCjsQ%3D%3D
    • (1982) Gastroenterology. , vol.83 , Issue.6 , pp. 1306-1312
    • Elashoff, J.D.1    Reedy, T.J.2    Meyer, J.H.3
  • 32
    • 0022848528 scopus 로고
    • Effect of the increase of the caloric load of a meal on gastric emptying of its solid and liquid phases
    • 3803825 1:STN:280:DyaL2s7gs1Gqtg%3D%3D
    • R Jian A Ruskone A Filali F Ducrot JD Rain JJ Bernier 1986 Effect of the increase of the caloric load of a meal on gastric emptying of its solid and liquid phases Gastroenterol Clin Biol. 10 12 831 836 3803825 1:STN:280:DyaL2s7gs1Gqtg%3D%3D
    • (1986) Gastroenterol Clin Biol. , vol.10 , Issue.12 , pp. 831-836
    • Jian, R.1    Ruskone, A.2    Filali, A.3    Ducrot, F.4    Rain, J.D.5    Bernier, J.J.6
  • 33
    • 0028260709 scopus 로고
    • Gastric emptying of water and isocratic carbohydrate solutions consumed at rest
    • 8052114 10.1249/00005768-199406000-00012 1:STN:280:DyaK2czivV2isw%3D%3D
    • R Murray DE Eddy WP Bartoli GL Paul 1994 Gastric emptying of water and isocratic carbohydrate solutions consumed at rest Med Sci Sports Exerc. 26 6 725 732 8052114 10.1249/00005768-199406000-00012 1:STN:280:DyaK2czivV2isw%3D%3D
    • (1994) Med Sci Sports Exerc. , vol.26 , Issue.6 , pp. 725-732
    • Murray, R.1    Eddy, D.E.2    Bartoli, W.P.3    Paul, G.L.4
  • 34
    • 0034947210 scopus 로고    scopus 로고
    • Effects of lansoprazole on human gastric lipase secretion and intragastric lipolysis in healthy human volunteers
    • 11435719 10.1159/000051891 1:CAS:528:DC%2BD3MXlslamtLo%3D
    • C Renou F Carrière E Ville P Grandval M Joubert-Collin R Laugier 2001 Effects of lansoprazole on human gastric lipase secretion and intragastric lipolysis in healthy human volunteers Digestion. 63 4 207 213 11435719 10.1159/000051891 1:CAS:528:DC%2BD3MXlslamtLo%3D
    • (2001) Digestion. , vol.63 , Issue.4 , pp. 207-213
    • Renou, C.1    Carrière, F.2    Ville, E.3    Grandval, P.4    Joubert-Collin, M.5    Laugier, R.6
  • 35
    • 34247355053 scopus 로고    scopus 로고
    • Effect of starch- and lipid-based encapsulation on the culturability of two Bifidobacterium longum strains
    • 17451516 10.1111/j.1472-765X.2007.02110.x 1:CAS:528:DC%2BD2sXntFOkt7w%3D
    • SJ Lahtinen AC Ouwehand SJ Salminen P Forssell P Myllärinen 2007 Effect of starch- and lipid-based encapsulation on the culturability of two Bifidobacterium longum strains Lett Appl Microbiol. 44 500 505 17451516 10.1111/j.1472-765X.2007.02110.x 1:CAS:528:DC%2BD2sXntFOkt7w%3D
    • (2007) Lett Appl Microbiol. , vol.44 , pp. 500-505
    • Lahtinen, S.J.1    Ouwehand, A.C.2    Salminen, S.J.3    Forssell, P.4    Myllärinen, P.5
  • 36
    • 0020441797 scopus 로고
    • Effet comparé de l'administration unique ou en continu de Saccharomyces boulardii sur l'établissement de diverses souches de Candida dans le tractus digestif de souris gnotoxéniques
    • 1:STN:280:DyaL3s7ltFSntA%3D%3D
    • R Ducluzeau M Bensaada 1982 Effet comparé de l'administration unique ou en continu de Saccharomyces boulardii sur l'établissement de diverses souches de Candida dans le tractus digestif de souris gnotoxéniques Ann Microbiol. 133 491 501 1:STN:280:DyaL3s7ltFSntA%3D%3D
    • (1982) Ann Microbiol. , vol.133 , pp. 491-501
    • Ducluzeau, R.1    Bensaada, M.2
  • 37
    • 0027367508 scopus 로고
    • Recovery and elimination of the biotherapeutic agent, Saccharomyces boulardii, in healthy human volunteers
    • 8290474 10.1023/A:1018924820333 1:CAS:528:DyaK2cXitlWjtQ%3D%3D
    • SM Klein GW Elmer LV McFarland CM Surawicz RH Levy 1993 Recovery and elimination of the biotherapeutic agent, Saccharomyces boulardii, in healthy human volunteers Pharm Res. 10 1615 1619 8290474 10.1023/A:1018924820333 1:CAS:528:DyaK2cXitlWjtQ%3D%3D
    • (1993) Pharm Res. , vol.10 , pp. 1615-1619
    • Klein, S.M.1    Elmer, G.W.2    McFarland, L.V.3    Surawicz, C.M.4    Levy, R.H.5
  • 38
    • 0018161279 scopus 로고
    • Degradation of polysaccharides by intestinal bacterial enzymes
    • 707363 1:STN:280:DyaE1M%2FjvFWitw%3D%3D
    • AA Salyers JK Palmer TD Wilkins 1978 Degradation of polysaccharides by intestinal bacterial enzymes Am J Clin Nutr. 31 S128 S130 707363 1:STN:280:DyaE1M%2FjvFWitw%3D%3D
    • (1978) Am J Clin Nutr. , vol.31
    • Salyers, A.A.1    Palmer, J.K.2    Wilkins, T.D.3
  • 39
    • 0026000612 scopus 로고
    • Kinetics of Saccharomyces cerevisiae elimination from the intestines of human volunteers and effect of this yeast on resistance to microbial colonization in gnotobiotic mice
    • 1746964 1:STN:280:DyaK38%2Fot1amug%3D%3D
    • S Pecquet D Guillaumin C Tancrede A Andremont 1991 Kinetics of Saccharomyces cerevisiae elimination from the intestines of human volunteers and effect of this yeast on resistance to microbial colonization in gnotobiotic mice Appl Environ Microbiol. 57 3049 3051 1746964 1:STN:280: DyaK38%2Fot1amug%3D%3D
    • (1991) Appl Environ Microbiol. , vol.57 , pp. 3049-3051
    • Pecquet, S.1    Guillaumin, D.2    Tancrede, C.3    Andremont, A.4
  • 40
    • 8644255761 scopus 로고    scopus 로고
    • Molecular and physiological comparisons between Saccharomyces cerevisiae and Saccharomyces boulardii
    • 15467787 10.1139/w04-050 1:CAS:528:DC%2BD2cXptlOlsLY%3D
    • JL Fietto RS Araujo FN Valadao LG Fietto RL Brandao MJ Neves, et al. 2004 Molecular and physiological comparisons between Saccharomyces cerevisiae and Saccharomyces boulardii Can J Microbiol. 50 615 621 15467787 10.1139/w04-050 1:CAS:528:DC%2BD2cXptlOlsLY%3D
    • (2004) Can J Microbiol. , vol.50 , pp. 615-621
    • Fietto, J.L.1    Araujo, R.S.2    Valadao, F.N.3    Fietto, L.G.4    Brandao, R.L.5    Neves, M.J.6
  • 41
    • 52649145404 scopus 로고    scopus 로고
    • Influence of pH conditions on the viability of Saccharomyces boulardii yeast
    • 18802321 10.2323/jgam.54.221 1:CAS:528:DC%2BD1cXhtFant7fP
    • S Graff JC Chaumeil P Boy R Lai-Kuen C Charrueau 2008 Influence of pH conditions on the viability of Saccharomyces boulardii yeast J Gen Appl Microbiol. 54 4 221 227 18802321 10.2323/jgam.54.221 1:CAS:528: DC%2BD1cXhtFant7fP
    • (2008) J Gen Appl Microbiol. , vol.54 , Issue.4 , pp. 221-227
    • Graff, S.1    Chaumeil, J.C.2    Boy, P.3    Lai-Kuen, R.4    Charrueau, C.5


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