TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity

American Journal of Physiology - Cell Physiology

Volumn 302, Issue 12, 2012, Pages

  Shahidullah, Mohammad ^a   Mandal, Amritlal ^a   Delamere, Nicholas A ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Connexin and pannexin; Src family kinase; TRPV4 channel

Indexed keywords

18ALPHA GLYCYRRHETINIC ACID; ADENOSINE TRIPHOSPHATE; CALCIUM; CONNEXIN 43; IONOMYCIN; PHOSPHOROUS ACID; PROBENECID; PROPIDIUM IODIDE; PROTEIN TYROSINE KINASE; SODIUM; VANILLOID RECEPTOR 4;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; EXPERIMENTAL PIG; HYPOSMOTIC SOLUTION; LENS EPITHELIUM; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SOLUTION AND SOLUBILITY;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CONNEXIN 43; CONNEXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EPITHELIUM; EYE PROTEINS; GLYCYRRHETINIC ACID; LENS, CRYSTALLINE; LEUCINE; MORPHOLINES; OSMOTIC PRESSURE; PROBENECID; PROPIDIUM; PYRROLES; SODIUM-POTASSIUM-EXCHANGING ATPASE; SRC-FAMILY KINASES; SULFONAMIDES; SWINE; TIME FACTORS; TISSUE CULTURE TECHNIQUES; TRPV CATION CHANNELS;

EID: 84862621270     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00010.2012     Document Type: Article

References (40)

1. +-ATPase activity is of importance for RVD. Acta Physiol Scand 180: 329-334, 2004.
2. Becker D, Blase C, Bereiter-Hahn J, Jendrach M. TRPV4 exhibits a functional role in cell-volume regulation. J Cell Sci 118: 2435-2440, 2005.
3. Chimote AA, Adragna NC, Lauf PK. Ion transport in a human lens epithelial cell line exposed to hyposmotic and apoptotic stress. J Cell Physiol 223: 110-122, 2010.
4. Clapham DE. TRP channels as cellular sensors. Nature 426: 517-524, 2003.
5. Clarke TC, Williams OJS, Martin PEM, Evans WH. ATP release by cardiac myocytes in a simulated ischaemia model: inhibition by a con-nexin mimetic and enhancement by an antiarrhythmic peptide. Eur J Pharmacol 605: 9-14, 2009.
6. De Vuyst E, Decrock E, Cabooter L, Dubyak GR, Naus CC, Evans WH, Leybaert L. Intracellular calcium changes trigger connexin 32 hemichannel opening. EMBO J 25: 34-44, 2006.
7. 2+ regulation of connexin 43 hemichannels in C6 glioma and glial cells. Cell Calcium 46: 176-187, 2009.
8. Delamere NA, Tamiya S. Expression, regulation and function of Na,K-ATPase in the lens. Progress Retinal Eye Res 23: 593-615, 2004.
9. Delamere NA, Tamiya S. Lens ion transport: from basic concepts to regulation of Na,K-ATPase activity. Exp Eye Res 88: 140-143, 2009.
10. Everaerts W, Nilius B, Owsianik G. The vanilloid transient receptor potential channel TRPV4: from structure to disease. Progress Biophys Mol Biol 103: 2-17, 2010.
11. Everaerts W, Zhen X, Ghosh D, Vriens J, Gevaert T, Gilbert JP, Hayward NJ, McNamara CR, Xue F, Moran MM, Strassmaier T, Uykal E, Owsianik G, Vennekens R, De Ridder D, Nilius B, Fanger CM, Voets T. Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proc Natl Acad Sci USA 107: 19084-19089, 2010.
12. Fan HC, Zhang X, McNaughton PA. Activation of the TRPV4 ion channel is enhanced by phosphorylation. J Biol Chem 284: 27884-27891, 2009.
13. Fernandes J, Lorenzo IM, Andrade YN, Garcia-Elias A, Serra SA, Fernandez-Fernandez JM, Valverde MA. IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeico-satrienoic acid. J Gen Physiol 131: i2, 2008.
14. Gomes P, Srinivas SP, Van Driessche W, Vereecke J, Himpens B. ATP release through connexin hemichannels in corneal endothelial cells. Invest Ophthalmol Vis Sci 46: 1208-1218, 2005.
15. Goswami C, Kuhn J, Heppenstall PA, Hucho T. Importance of nonselective cation channel TRPV4 interaction with cytoskeleton and their reciprocal regulations in cultured cells. PLos One 5: e11654, 2010.
16. Gradilone SA, Masyuk AI, Splinter PL, Banales JM, Huang BQ, Tietz PS, Masyuk TV, Larusso NF. Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion. Proc Natl Acad Sci USA 104: 19138-19143, 2007.
17. John SA, Kondo R, Wang SY, Goldhaber JI, Weiss JN. Connexin-43 hemichannels opened by metabolic inhibition. J Biol Chem 274: 236-240, 1999.
18. Kong CW, Gerometta R, Alvarez LJ, Candia OA. Changes in rabbit and cow lens shape and volume upon imposition of anisotonic conditions. Exp Eye Res 89: 469-478, 2009.
19. Li A, Leung CT, Peterson-Yantorno K, Mitchell CH, Civan MM. Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow. Am J Physiol Cell Physiol 299: C1308-C1317, 2010.
20. Li A, Leung CT, Peterson-Yantorno K, Stamer WD, Mitchell CH, Civan MM. Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow. J Cell Physiol 227: 172-182, 2012.
21. Locovei S, Wang J, Dahl G. Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium. FEBS Lett 580: 239-244, 2006.
22. Ma W, Hui H, Pelegrin P, Surprenant A. Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. J Pharmacol Exp Ther 328: 409-418, 2009.
23. Mandal A, Shahidullah M, Delamere NA. Hydrostatic pressure-induced release of stored calcium in cultured rat optic nerve head astrocytes. Invest Ophthalmol Vis Sci 51: 3129-3138, 2010.
24. Mihara H, Boudaka A, Sugiyama T, Moriyama Y, Tominaga M. Transient receptor potential vanilloid 4 (TRPV4)-dependent calcium influx and ATP release in mouse oesophageal keratinocytes. J Physiol 589: 3471-3482, 2011.
25. 2+ influx and ATP release in primary urothelial cell cultures. J Biol Chem 284: 21257-21264, 2009.
26. Nilius B, Vriens J, Prenen J, Droogmans G, Voets T. TRPV4 calcium entry channel: a paradigm for gating diversity. Am J Physiol Cell Physiol 286: C195-C205, 2004.
27. Pan Z, Yang H, Mergler S, Liu H, Tachado SD, Zhang F, Kao WWY, Koziel H, Pleyer U, Reinach PS. Dependence of regulatory volume decrease on transient receptor potential vanilloid 4 (TRPV4) expression in human corneal epithelial cells. Cell Calcium 44: 374-385, 2008.
28. Pollreisz A, Schmidt-Erfurth U. Diabetic cataract-pathogenesis, epidemiology, and treatment. J Ophthalmol 2010; 608751, 2010.
29. Robison WG Jr, Houlder N, Kinoshita JH. The role of lens epithelium in sugar cataract formation. Exp Eye Res 50: 641-646, 1990.
30. Seminario-Vidal L, Okada SF, Sesma JI, Kreda SM, van Heusden CA, Zhu Y, Jones LC, O'Neal WK, Penuela S, Laird DW, Boucher RC, Lazarowski ER. Rho signaling regulates pannexin 1-mediated ATP release from airway epithelia. J Biol Chem 286: 26277-26286, 2011.
31. Shahidullah M, Delamere NA. NO donors inhibit Na,K-ATPase activity by a protein kinase G-dependent mechanism in the nonpigmented ciliary epithelium of the porcine eye. Br J Pharmacol 148: 871-880, 2006.
32. Shahidullah M, Mandal A, Beimgraben C, Delamere NA. Hyposmotic stress causes ATP release and stimulates Na,K-ATPase activity in porcine lens. J Cell Physiol 227: 1428-1437, 2012.
33. Silva GB, Garvin JL. TRPV4 mediates hypotonicity-induced ATP release by the thick ascending limb. Am J Physiol Renal Physiol 295: F1090-F1095, 2008.
34. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC.Measurement of protein using bicinchoninic acid. Analyt Biochem 150: 76-85, 1985.
35. Tamiya S, Dean WL, Paterson CA, Delamere NA. Regional distribution of Na,K-ATPase activity in porcine lens epithelium. Invest Ophthalmol Vis Sci 44: 4395-4399, 2003.
36. Thorneloe KS, Sulpizio AC, Lin Z, Figueroa DJ, Clouse AK, Mc-Cafferty GP, Chendrimada TP, Lashinger ESR, Gordon E, Evans L, Misajet BA, Demarini DJ, Nation JH, Casillas LN, Marquis RW, Votta BJ, Sheardown SA, Xu X, Brooks DP, Laping NJ, Westfall TD.N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxy-propanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinary bladder contraction and hyperactivity: part I. J Pharmacol Exp Ther 326: 432-442, 2008.
37. + in human esophageal epithelial cells. Am J Physiol Gastrointest Liver Physiol 301: G138-G147, 2011.
38. Vriens J, Appendino G, Nilius B. Pharmacology of vanilloid transient receptor potential cation channels. Mol Pharmacol 75: 1262-1279, 2009.
39. +-ATPase. Methods Enzymol 156: 201-213, 1988.
40. +)-ATPase activity of isolated or cultured cells. Analyt Biochem 183: 215-219, 1989.