ATP release through connexin hemichannels in corneal endothelial cells

Investigative Ophthalmology and Visual Science

Volumn 46, Issue 4, 2005, Pages 1208-1218

  Gomes, Priya ^a   Srinivas, Sangly P ^b   Van Driessche, Willy ^a   Vereecke, Johan ^a   Himpens, Bernard ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 CARBOXYFLUORESCEIN; ADENOSINE TRIPHOSPHATE; BETA,GAMMA DIBROMOMETHYLENE 6 N,N DIETHYLADENOSINE TRIPHOSPHATE; FLUFENAMIC ACID; GAP JUNCTION PROTEIN; LUCIFER YELLOW; PURINE P2Y RECEPTOR; ANILINE DERIVATIVE; CALCIUM; CONNEXIN 26; FLUO 4; FLUORESCENT DYE; ION CHANNEL; ISOQUINOLINE DERIVATIVE; XANTHENE DERIVATIVE;

ANIMAL CELL; ARTICLE; BIOLUMINESCENCE; CALCIUM CELL LEVEL; CELL COMMUNICATION; CORNEA ENDOTHELIUM; COW; ENDOTHELIUM CELL; ENZYME INHIBITION; EXTRACELLULAR CALCIUM; MECHANICAL STIMULATION; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; STIMULUS RESPONSE; VASCULAR ENDOTHELIUM; ANIMAL; CATTLE; CELL CULTURE; CELL JUNCTION; MECHANICAL STRESS; METABOLISM; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANILINE COMPOUNDS; ANIMALS; CALCIUM; CATTLE; CELL COMMUNICATION; CELLS, CULTURED; CONNEXINS; ENDOTHELIUM, CORNEAL; FLUFENAMIC ACID; FLUORESCENT DYES; GAP JUNCTIONS; ION CHANNELS; ISOQUINOLINES; STRESS, MECHANICAL; XANTHENES;

EID: 18244365858     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.04-1181     Document Type: Article

References (79)

1. Cotrina ML, Lin JH, Lopez-Garcia JC, et al. ATP-mediated glia signaling. J Neurosci. 2000;20:2835-2844.
2. Braet K, Paemeleire K, D'Herde K, et al. Astrocyte-endothelial cell calcium signals conveyed by two signalling pathways. Eur J Neurosci. 2001;13:79-91.
3. 2+ signaling in retinal pigment epithelial cells during mechanical stimulation. FASEB J. 1999;13:S63-S68.
4. Gomes P, Srinivas SP, Vereecke J, Himpens B. ATP-dependent paracrine intercellular communication in cultured bovine corneal endothelial cells. Invest Ophthalmol Vis Sci. 2005;46:104-113.
5. Charles AC, Merrill JE, Dirksen ER, Sanderson MJ. Intercellular signaling in glial cells: calcium waves and oscillations in response to mechanical stimulation and glutamate. Neuron. 1991;6:983-992.
6. Paemeleire K, Leybaert L. ATP-dependent astrocyte-endothelial calcium signaling following mechanical damage to a single astrocyte in astrocyte-endothelial co-cultures. J Neurotrauma. 2000;17:345-358.
7. Frame MK, de Feijter AW. Propagation of mechanically induced intercellular calcium waves via gap junctions and ATP receptors in rat liver epithelial cells. Exp Cell Res. 1997;230:197-207.
8. Sanderson MJ. Intercellular calcium waves mediated by inositol trisphosphate. Ciba Found Symp. 1995;188:175-189.
9. Moerenhout M, Himpens B, Vereecke J. Intercellular communication upon mechanical stimulation of CPAE-endothelial cells is mediated by nucleotides. Cell Calcium. 2001;29:125-136.
10. - permeability across the apical membrane of bovine corneal endothelium by multiple signaling pathways. Invest Ophthalmol Vis Sci. 2002;43:1146-1153.
11. Boland B, Himpens B, Vincent MF, et al. ATP activates P2x-contracting and P2y-relaxing purinoceptors in the smooth muscle of mouse vas deferens. Br J Pharmacol. 1992;107:1152-1158.
12. Riley MV, Winkler BS, Starnes CA, et al. Regulation of corneal endothelial barrier function by adenosine, cyclic AMP, and protein kinases. Invest Ophthalmol Vis Sci. 1998;39:2076-2084.
13. Bonanno JA. Identity and regulation of ion transport mechanisms in the corneal endothelium. Prog Retin Eye Res. 2003;22:69-94.
14. 2+ mobilization in bovine corneal endothelial cells by P2 purinergic receptors. Curr Eye Res. 1998;17:994-1004.
15. Okada Y, Maeno E, Shimizu T, et al. Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD). J Physiol. 2001;532:3-16.
16. Morrone FB, Jacques-Silva MC, Horn AP, et al. Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines. J Neurooncol. 2003;64:211-218.
17. Cha SH, Hahn TW, Sekine T, et al. Purinoceptor-mediated calcium mobilization and cellular proliferation in cultured bovine corneal endothelial cells. Jpn J Pharmacol. 2000;82:181-187.
18. Burnstock G. Purinergic signaling and vascular cell proliferation and death. Arterioscler Thromb Vasc Biol. 2002;22:364-373.
19. Greig AV, Linge C, Terenghi G, et al. Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes. J Invest Dermatol. 2003;120:1007-1015.
20. Illes P, Alexandre Ribeiro J. Molecular physiology of P2 receptors in the central nervous system. Eur J Pharmacol. 2004;483:5-17.
21. Dell'Antonio G, Quattrini A, Cin ED, et al. Relief of inflammatory pain in rats by local use of the selective P2X7 ATP receptor inhibitor, oxidized ATP. Arthritis Rheum. 2002;46:3378-3385.
22. Dubyak GR, el-Moatassim C. Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am J Physiol. 1993;265:C577-C606.
23. Brake AJ, Julius D. Signaling by extracellular nucleotides. Annu Rev Cell Dev Biol. 1996;12:519-541.
24. Forrester T. A quantitative estimation of adenosine triphosphate released from human forearm muscle during sustained exercise. J Physiol. 1972;221:25P-26P.
25. Bodin P, Burnstock G. Purinergic signalling: ATP release. Neurochem Res. 2001;26:959-969.
26. Sprague RS, Ellsworth ML, Stephenson AH, Lonigro AJ. ATP: the red blood cell link to NO and local control of the pulmonary circulation. Am J Physiol. 1996;271:H2717-H2722.
27. Ferguson DR, Kennedy I, Burton TJ. ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes: a possible sensory mechanism? J Physiol. 1997;505:503-511.
28. Wang Y, Roman R, Lidofsky SD, Fitz JG. Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation. Proc Natl Acad Sci USA. 1996;93:12020-12025.
29. Mitchell CH, Carre DA, McGlinn AM, et al. A release mechanism for stored ATP in ocular ciliary epithelial cells. Proc Natl Acad Sci USA. 1998;95:7174-7178.
30. Crosson CE, Gray T. Characterization of ocular hypertension induced by adenosine agonists. Invest Ophthalmol Vis Sci. 1996;37:1833-1839.
31. Lazarowski ER, Boucher RC, Harden TK. Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y-receptor activating molecules. Mol Pharmacol. 2003;64:785-795.
32. Borst P, Elferink RO. Mammalian ABC transporters in health and disease. Annu Rev Biochem. 2002;71:537-592.
33. Rostovtseva T, Colombini M. VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function. Biophys J. 1997;72:1954-1962.
34. Stout CE, Costantin JL, Naus CC, Charles AC. Intercellular calcium signaling in astrocytes via ATP release through connexin hemichannels. J Biol Chem. 2002;10482-10488.
35. Braet K, Vandamme W, Martin PE, et al. Photoliberating inositol-1,4,5-trisphosphate triggers ATP release that is blocked by the connexin mimetic peptide gap 26. Cell Calcium. 2003;33:37-48.
36. Goodenough DA, Paul DL. Beyond the gap: functions of unpaired connexon channels. Nat Rev Mol Cell Biol. 2003;4:285-294.
37. i in rabbit ventricular myocytes during metabolic inhibition. J Mol Cell Cardiol. 2001;33:2145-2155.
38. Bonanno JA, Srinivas SP. Cyclic AMP activates anion channels in cultured bovine corneal endothelial cells. Exp Eye Res. 1997;64:953-962.
39. - exchange. Invest Ophthalmol Vis Sci. 1992;33:3068-3079.
40. MacCallum DK, Bahn CF, Lillie JH, et al. Evidence for corneal endothelial cell hypertrophy during postnatal growth of the cat cornea. Invest Ophthalmol Vis Sci. 1983;24:247-250.
41. Jans D, Srinivas SP, Waelkens E, et al. Hypotonic treatment evokes biphasic ATP release across the basolateral membrane of cultured renal epithelia (A6). J Physiol. 2002;545:543-555.
42. Leybaert L, Braet K, Vandamme W, et al. Connexin channels, connexin mimetic peptides and ATP release. Cell Commun Adhes. 2003;10:251-257.
43. Mohay J, McLaughlin BJ. Corneal endothelial wound repair in normal and mitotically inhibited cultures. Graefes Arch Clin Exp Ophthalmol. 1995;233:727-736.
44. Hofer A, Dermietzel R. Visualization and functional blocking of gap junction hemichannels (connexons) with antibodies against external loop domains in astrocytes. Glia. 1998;24:141-154.
45. Valiunas V. Biophysical properties of connexin-45 gap junction hemichannels studied in vertebrate cells. J Gen Physiol. 2002;119:147-164.
46. Guyot A, Hanrahan JW. ATP release from human airway epithelial cells studied using a capillary cell culture system. J Physiol. 2002;545:199-206.
47. Oike M, Droogmans G, Ito Y. ATP release pathways in vascular endothelial cells (in Japanese). Nippon Yakurigaku Zasshi. 2004;123:403-411.
48. Taylor AL, Kudlow BA, Marrs KL, et al. Bioluminescence detection of ATP release mechanisms in epithelia. Am J Physiol. 1998;275:C1391-C1406.
49. Wilson PD, Hovater JS, Casey CC, et al. ATP release mechanisms in primary cultures of epithelia derived from the cysts of polycystic kidneys. J Am Soc Nephrol. 1999;10:218-229.
50. Anderson CM, Bergher JP, Swanson RA. ATP-induced ATP release from astrocytes. J Neurochem. 2004;88:246-256.
51. + channel in human airway Calu-3 cells. Am J Respir Cell Mol Biol. 2004;30:388-395.
52. Coco S, Calegari F, Pravettoni E, et al. Storage and release of ATP from astrocytes in culture. J Biol Chem. 2003;278:1354-1362.
53. 2+ and cyclic AMP in cultured human bronchial cells. Jpn J Physiol. 2003;53:319-326.
54. i is involved in a signal transduction pathway for ATP release from erythrocytes. Am J Physiol. 2004;286:H940-H945.
55. Boudreault F, Grygorczyk R. Cell swelling-induced ATP release and gadolinium-sensitive channels. Am J Physiol. 2002;282:C219-C226.
56. Stout C, Charles A. Modulation of intercellular calcium signaling in astrocytes by extracellular calcium and magnesium. Glia. 2003;43:265-273.
57. Suh BC, Kim JS, Namgung U, et al. P2X7 nucleotide receptor mediation of membrane pore formation and superoxide generation in human promyelocytes and neutrophils. J Immunol. 2001;166:6754-6763.
58. Fortes FS, Pecora IL, Persechini PM, et al. Modulation of intercellular communication in macrophages: possible interactions between GAP junctions and P2 receptors. J Cell Sci. 2004;117:4717-4726.
59. - permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes. J Biol Chem. 1987;262:8884-8888.
60. Nuttle LC, Dubyak GR. Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes. J Biol Chem. 1994;269:13988-13996.
61. Duan S, Anderson CM, Keung EC, et al. P2X7 receptor-mediated release of excitatory amino acids from astrocytes. J Neurosci. 2003;23:1320-1328.
62. 2+ stores in bovine corneal endothelium. Invest Ophthalmol Vis Sci. 2002;43:2341-2350.
63. Srinivas SP, Bonanno JA, Hughes BA. Assessment of swelling-activated Cl- channels using the halide-sensitive fluorescent indicator 6-methoxy-N-(3- sulfopropyl)quinolinium. Biophys J. 1998;75:115-123.
64. Braet K, Aspeslagh S, Vandamme W, et al. Pharmacological sensitivity of ATP release triggered by photoliberation of inositol-1,4,5-trisphosphate and zero extracellular calcium in brain endothelial cells. J Cell Physiol. 2003;197:205-213.
65. Williams K, Watsky M. Gap junctional communication in the human corneal endothelium and epithelium. Curr Eye Res. 2002;25:29-36.
66. Lazarowski ER, Homolya L, Boucher RC, Harden TK. Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation. J Biol Chem. 1997;272:24348-24354.
67. Joseph SM, Buchakjian MR, Dubyak GR. Colocalization of ATP release sites and ecto-ATPase activity at the extracellular surface of human astrocytes. J Biol Chem. 2003;278:23331-23342.
68. Lazarowski ER, Boucher RC, Harden TK. Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide concentrations. J Biol Chem. 2000;275:31061-31068.
69. Beigi R, Kobatake E, Aizawa M, Dubyak GR. Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase. Am J Physiol. 1999;276:C267-C278.
70. Bodin P, Burnstock G. Evidence that release of adenosine triphosphate from endothelial cells during increased shear stress is vesicular. J Cardiovasc Pharmacol. 2001;38:900-908.
71. Gatof D, Kilic G, Fitz JG. Vesicular exocytosis contributes to volume-sensitive ATP release in biliary cells. Am J Physiol. 2004;286:G538-G546.
72. Abdipranoto A, Liu GJ, Werry EL, Bennett MR. Mechanisms of secretion of ATP from cortical astrocytes triggered by uridine triphosphate. Neuroreport. 2003;14:2177-2181.
73. Abraham EH, Prat AG, Gerweck L, et al. The multidrug resistance (mdr1) gene product functions as an ATP channel. Proc Natl Acad Sci U S A. 1993;90:312-316.
74. Reisin IL, Prat AG, Abraham EH, et al. The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel. J Biol Chem. 1994;269:20584-20591.
75. Sabirov RZ, Dutta AK, Okada Y. Volume-dependent ATP-conductive large-conductance anion channel as a pathway for swelling-induced ATP release. J Gen Physiol. 2001;118:251-266.
76. Hisadome K, Koyama T, Kimura C, et al. Volume-regulated anion channels serve as an auto/paracrine nucleotide release pathway in aortic endothelial cells. J Gen Physiol. 2002;119:511-520.
77. Bruzzone R, Hormuzdi SG, Barbe MT, et al. Pannexins, a family of gap junction proteins expressed in brain. Proc Natl Acad Sci USA. 2003;100:13644-13649.
78. Bao L, Locovei S, Dahl G. Pannexin membrane channels are mechanosensitive conduits for ATP. FEBS Letts. 2004;572:65-68.
79. John SA, Kondo R, Wang SY, et al. Connexin-43 hemichannels opened by metabolic inhibition. J Biol Chem. 1999;274:236-240.