Vacuolar-type H +-ATPase-mediated proton transport in the rat parietal cell

Pflugers Archiv European Journal of Physiology

Volumn 463, Issue 3, 2012, Pages 419-427

  Kopic, Sascha ^a   Wagner, Maximilian E H ^a,b   Griessenauer, Christoph ^a,b   Socrates, Thenral ^a   Ritter, Markus ^b   Geibel, John P ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PARACELSUS MEDICAL UNIVERSITY   (Austria)

Author keywords

Acid breakthrough; Acid secretion; Ion transport; Stomach; V ATPase; Vacuolar type H + ATPase

Indexed keywords

HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; PACLITAXEL; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; ACETYLCHOLINE; CARBACHOL; CONCANAMYCIN A; HISTAMINE; MACROLIDE; PENTAGASTRIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ACIDIFICATION; ALKALINIZATION; ANALYSIS OF VARIANCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME RELEASE; EPIDIDYMIS; IMMUNOHISTOCHEMISTRY; MICROTUBULE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON TRANSPORT; RAT; STOICHIOMETRY; STOMACH ACID SECRETION; STOMACH GLAND; STOMACH PARIETAL CELL; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; ION TRANSPORT; METABOLISM; PROTON MOTIVE FORCE; SPRAGUE DAWLEY RAT;

ACETYLCHOLINE; ANIMALS; CARBACHOL; HISTAMINE; ION TRANSPORT; MACROLIDES; PARIETAL CELLS, GASTRIC; PENTAGASTRIN; PROTON-MOTIVE FORCE; RATS; RATS, SPRAGUE-DAWLEY; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84862606135     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-011-1060-0     Document Type: Article

References (31)

1. Andersen OS, Silveira JE, Steinmetz PR (1985) Intrinsic characteristics of the proton pump in the luminal membrane of a tight urinary epithelium. The relation between transport rate and delta mu H. J Gen Physiol 86:215-234
2. Bastani B, Purcell H, Hemken P, Trigg D, Gluck S (1991) Expression and distribution of renal vacuolar proton-translocating adenosine triphosphatase in response to chronic acid and alkali loads in the rat. J Clin Invest 88:126-136
3. Blair HC, Teitelbaum SL, Ghiselli R, Gluck S (1989) Osteoclastic bone resorption by a polarized vacuolar proton pump. Science 245:855-857
4. Breton S, Brown D (1998) Cold-induced microtubule disruption and relocalization of membrane proteins in kidney epithelial cells. J Am Soc Nephrol 9:155-166
5. Breton S, Smith PJ, Lui B, Brown D (1996) Acidification of the male reproductive tract by a proton pumping (H+)-ATPase. Nat Med 2:470-472
6. Brown D, Breton S (2000) H(+)V-ATPase-dependent luminal acidification in the kidney collecting duct and the epididymis/vas deferens: vesicle recycling and transcytotic pathways. J Exp Biol 203:137-145
7. Brown D, Sabolic I, Gluck S (1991) Colchicine-induced redistribution of proton pumps in kidney epithelial cells. Kidney Int Suppl 33:S79-S83
8. Finberg KE, Wagner CA, Bailey MA, Paunescu TG, Breton S, Brown D, Giebisch G, Geibel JP, Lifton RP (2005) The B1-subunit of the H(+) ATPase is required for maximal urinary acidification. Proc Natl Acad Sci U S A 102:13616-13621. doi:10.1073/pnas.0506769102
9. Geibel JP, Wagner CA, Caroppo R, Qureshi I, Gloeckner J, Manuelidis L, Kirchhoff P, Radebold K (2001) The stomach divalent ion-sensing receptor scar is a modulator of gastric acid secretion. J Biol Chem 276:39549-39552. doi:10.1074/jbc.M107315200
10. Gerson LB, Boparai V, Ullah N, Triadafilopoulos G (2004) Oesophageal and gastric pH profiles in patients with gastrooesophageal reflux disease and Barrett's oesophagus treated with proton pump inhibitors. Aliment Pharmacol Ther 20:637-643. doi:10.1111/j.1365-2036.2004.02127.x
11. Gorodeski GI, Hopfer U, Liu CC, Margles E (2005) Estrogen acidifies vaginal pH by up-regulation of proton secretion via the apical membrane of vaginal-ectocervical epithelial cells. Endocrinology 146:816-824. doi:10.1210/en.2004-1153
12. Gumz ML, Lynch IJ, Greenlee MM, Cain BD, Wingo CS (2010) The renal H+-K+-ATPases: physiology, regulation, and structure. Am J Physiol Renal Physiol 298:F12-F21. doi:10.1152/ajprenal.90723.2008
13. Judd LM, Andringa A, Rubio CA, Spicer Z, Shull GE, Miller ML (2005) Gastric achlorhydria in H/K-ATPase-deficient (Atp4a(-/-)) mice causes severe hyperplasia, mucocystic metaplasia and upregulation of growth factors. J Gastroenterol Hepatol 20:1266-1278. doi:10.1111/j.1440-1746.2005.03867.x
14. Kettner C, Bertl A, Obermeyer G, Slayman C, Bihler H (2003) Electrophysiological analysis of the yeast V-type proton pump: variable coupling ratio and proton shunt. Biophys J 85:3730-3738. doi:10.1016/S0006-3495(03) 74789-4
15. Kopic S, Murek M, Geibel JP (2010) Revisiting the parietal cell. Am J Physiol Cell Physiol 298:C1-C10. doi:10.1152/ajpcell.00478.2009
16. Kuo B, Castell DO (1996) Optimal dosing of omeprazole 40 mg daily: effects on gastric and esophageal pH and serum gastrin in healthy controls. Am J Gastroenterol 91:1532-1538
17. Leite LP, Johnston BT, Just RJ, Castell DO (1996) Persistent acid secretion during omeprazole therapy: a study of gastric acid profiles in patients demonstrating failure of omeprazole therapy. Am J Gastroenterol 91:1527-1531
18. Paunescu TG, Ljubojevic M, Russo LM, Winter C, McLaughlin MM, Wagner CA, Breton S, Brown D (2010) cAMP stimulates apical V-ATPase accumulation, microvillar elongation, and proton extrusion in kidney collecting duct A-intercalated cells. Am J Physiol Renal Physiol 298:F643-F654. doi:10.1152/ajprenal.00584.2009
19. Sawaguchi A, McDonald KL, Forte JG (2004) High-pressure freezing of isolated gastric glands provides new insight into the fine structure and subcellular localization of H+/K+-ATPase in gastric parietal cells. J Histochem Cytochem 52:77-86
20. Schinke T, Schilling AF, Baranowsky A, Seitz S, Marshall RP, Linn T, Blaeker M, Huebner AK, Schulz A, Simon R, Gebauer M, Priemel M, Kornak U, Perkovic S, Barvencik F, Beil FT, Del Fattore A, Frattini A, Streichert T, Pueschel K, Villa A, Debatin KM, Rueger JM, Teti A, Zustin J, Sauter G, Amling M (2009) Impaired gastric acidification negatively affects calcium homeostasis and bone mass. Nat Med 15:674-681. doi:10.1038/nm.1963
21. Shin JM, Munson K, Vagin O, Sachs G (2009) The gastric HKATPase: structure, function, and inhibition. Pflugers Arch 457:609-622. doi:10.1007/s00424-008-0495-4
22. Silver IA, Murrills RJ, Etherington DJ (1988) Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts. Exp Cell Res 175:266-276
23. Singh SK, Binder HJ, Geibel JP, Boron WF (1995) An apical permeability barrier to NH3/NH4+ in isolated, perfused colonic crypts. Proc Natl Acad Sci U S A 92:11573-11577
24. Spicer Z, Miller ML, Andringa A, Riddle TM, Duffy JJ, Doetschman T, Shull GE (2000) Stomachs of mice lacking the gastric H, K-ATPase alpha-subunit have achlorhydria, abnormal parietal cells, and ciliated metaplasia. J Biol Chem 275:21555-21565. doi:10.1074/jbc.M001558200
25. Stankovic KM, Brown D, Alper SL, Adams JC (1997) Localization of pH regulating proteins H+ATPase and Cl-/HCO3-exchanger in the guinea pig inner ear. Hear Res 114:21-34. doi:10.1016/S0378-5955(97)00072-5
26. Tutuian R, Castell DO (2004) Nocturnal acid breakthrough-approach to management. Med Gen Med 6:11
27. Wagner CA, Giebisch G, Lang F, Geibel JP (1998) Angiotensin II stimulates vesicular H+-ATPase in rat proximal tubular cells. Proc Natl Acad Sci U S A 95:9665-9668. doi:10.1073/pnas.95.16.9665
28. Wagner CA, Finberg KE, Breton S, Marshansky V, Brown D, Geibel JP (2004) Renal vacuolar H+-ATPase. Physiol Rev 84:1263-1314. doi:10.1152/physrev.00045. 2003
29. Waisbren SJ, Geibel J, Boron WF, Modlin IM (1994) Luminal perfusion of isolated gastric glands. AmJ Physiol 266:C1013-C1027
30. Waisbren SJ, Geibel JP, Modlin IM, Boron WF (1994) Unusual permeability properties of gastric gland cells. Nature 368:332-335. doi:10.1038/368332a0
31. Winter C, Schulz N, Giebisch G, Geibel JP, Wagner CA (2004) Nongenomic stimulation of vacuolar H+-ATPases in intercalated renal tubule cells by aldosterone. Proc Natl Acad Sci U S A 101:2636-2641. doi:10.1073/pnas.0307321101