Acidification of the male reproductive tract by a proton pumping (H+)-ATPase

Nature Medicine

Volumn 2, Issue 4, 1996, Pages 470-472

  Breton, Sylvie ^a   Smith, Peter J S ^b   Lui, Ben ^a   Brown, Dennis ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MARINE BIOLOGICAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAFILOMYCIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ACIDIFICATION; ANIMAL TISSUE; ARTICLE; EPIDIDYMIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; RAT; VAS DEFERENS;

ANIMALS; ANTI-BACTERIAL AGENTS; HYDROGEN-ION CONCENTRATION; MACROLIDES; MALE; PROTON PUMPS; PROTON-TRANSLOCATING ATPASES; RATS; RATS, SPRAGUE-DAWLEY; SPERM MATURATION; VAS DEFERENS;

ANIMALIA;

EID: 0029898733     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0496-470     Document Type: Article

References (23)

1. Caflisch, C.R. & DuBose, T.D.J. Direct evaluation of acidification by rat testis and epididymis: role of carbonic anhydrase. Am. J. Physiol. 258, E143-E150 (1990).
2. Carr, W.D., Usselman, M.C. & Acott, T.S. Effect of pH, lactate, and viscoelastic drag on sperm motility: A species comparison. Biol. Reprod. 33, 588-595 (1985).
3. Levine, N. & Kelly, H. Measurement of pH in the rat epididymis in vivo. J. Reprod. Fertil. 52, 333-335 (1978).
4. Hinton, B.T. & Palladino, M.A. Epididymal epithelium: Its contribution to the formation of a luminal fluid microenvironment. Microsc. Res. Tech. 30, 67-81 (1995).
5. Usselman, M.C. & Cone, R.A. Rat sperm are mechanically immobilized in the caudal epididymis by "immobilin", a high molecular weight glycoprotein. Biol. Reprod. 29, 1241-1253 (1983).
6. Wong, P.Y., Tsang, A.Y. & Lee, W.M. Effect of intraluminal ion concentrations on the secretion of the rat cauda epididymidis in vivo. Pflugers Arch. 387, 61-66 (1980).
7. Acott, T.S. & Carr, D.W. Inhibition of bovine spermatozoa by caudal epididymal fluid. II. Interaction of pH and a quiescence factor. Biol. Reprod. 30, 926-935 (1984).
8. Carr, D.W. & Acott, T.S. Intracellular pH regulates bovine sperm motility and protein phosphorylation. Biol. Reprod. 41, 907-920 (1989).
9. Brown, D., Lui, B., Gluck, S. & Sabolic, I. A plasma membrane proton ATPase in specialized cells of rat epididymis. Am. J. Physiol. 263, C913-C916 (1992).
10. Brown, D., Hirsch, S. & Gluck, S. Localization of a proton-pumping ATPase in rat kidney. J. Clin. Invest. 82, 2114-2126 (1988).
11. +-ATPase is present in opposite plasma membrane domains in kidney epithelial cell subpopulations. Nature 331, 622-624 (1988).
12. Au, C.L. & Wong, P.Y. Luminal acidification by the perfused rat cauda epididymidis. J. Physiol. (Lond.) 309, 419-427 (1980).
13. Cohen, J.P., Hoffer, A.P. & Rosen, S. Carbonic anhydrase localization in the epididymis and testis of the rat: Histochemical and biochemical analysis. Biol. Reprod. 14, 339-346 (1976).
14. Ekstedt, E., Ridderstrale, Y., Ploen, L. & Rodriguez-Martinez, H. Histochemical localization of carbonic anhydrase in the testis and epididymis of the boar. Acta Anat. 141, 257-261 (1991).
15. Ekstedt, E. & Ridderstrale, Y. Histochemical localization of carbonic anhydrase in the testis and epididymis of the rabbit. Acta Anat. 143, 258-264 (1992).
16. Kaunisto, K. et al. Expression of carbonic anhydrase isoenzymes IV and II in rat epididymal duct. Biol. Reprod. 52, 1350-1357 (1995).
17. Lewis, S.E., Erickson, R.P., Barnett, L.B., Venta, P.J. & Tashian, R.E. N-Ethyl-nitrosourea-induced null mutation at the mouse Car-2 locus: An animal model for human carbonic anhydrase II deficiency syndrome. Proc. Natl. Acad. Sci. USA 85, 1962-1966 (1988).
18. Steinmetz, P.R. Cellular organization of urinary acidification. Am. J. Physiol. 251, F173-F187 (1986).
19. Al-Awqati, Q. Regulation of membrane transport by endocytotic removal and exocytotic insertion of transporters. Methods Enzymol. 172, 49-59 (1989).
20. Schuster, V.L. Function and regulation of collecting duct intercalated cells. Annu. Rev. Physiol. 55, 267-288 (1993).
21. +-ATPase in cortical collecting tubules of a patient with Sjögren's syndrome and distal renal tubular acidosis. J. Am. Soc. Nephrol. 3, 264-271 (1992).
22. Sly, W.S., Whyte, M.P., Krupin, T. & Sundaram, V. Positive renal response to intravenous acetazolamide in patients with carbonic anhydrase II deficiency. Pediatr. Res. 19, 1033-1036 (1985).
23. 2+ influx and efflux. Methods Cell Biol. 40, 115-134 (1994).