Genetic merit for fertility traits in Holstein cows: III. Hepatic expression of somatotropic axis genes during pregnancy and lactation

Journal of Dairy Science

Volumn 95, Issue 7, 2012, Pages 3711-3721

  Cummins, S B ^a,b   Waters, S M ^a   Evans, A C O ^b   Lonergan, P ^b   Butler, S T ^a  

^a ANIMAL AND GRASSLAND RESEARCH AND INNOVATION CENTRE   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Fertility; Genetic merit for fertility; Insulin like growth factor I; Somatotropic axis

Indexed keywords

CARRIER PROTEIN; GLYCOPROTEIN; GROWTH HORMONE RECEPTOR; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN, ACID LABILE SUBUNIT; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN, ACID LABILE SUBUNIT; JANUS KINASE 2; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL; ARTICLE; BREEDING; CATTLE; CHEMISTRY; FEMALE; FERTILITY; GENE; GENETICS; LACTATION; LIVER; METABOLISM; PHYSIOLOGY; PREGNANCY; QUANTITATIVE TRAIT;

ANIMALS; CARRIER PROTEINS; CATTLE; FEMALE; FERTILITY; GENES; GLYCOPROTEINS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INSULIN-LIKE GROWTH FACTOR I; JANUS KINASE 2; LACTATION; LIVER; PREGNANCY; PREGNANCY, ANIMAL; QUANTITATIVE TRAIT, HERITABLE; RECEPTORS, SOMATOTROPIN; STAT5 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84862580665     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2011-4977     Document Type: Article

References (42)

1. Bauman D.E. Regulation of nutrient partitioning during lactation: Homeostasis and homeorhesis revisited. Ruminant Physiology: Digestion, Metabolism and Growth and Reproduction 2000, 311-327. CABI Publishing, New York, NY.
2. Bauman D.E., Currie W.B. Partitioning of nutrients during pregnancy and lactation: A review of mechanisms involving homeostasis and homeorhesis. J. Dairy Sci. 1980, 63:1514-1529.
3. Butler S.T., Marr A.L., Pelton S.H., Radcliff R.P., Lucy M.C., Butler W.R. Insulin restores GH responsiveness during lactation-induced negative energy balance in dairy cattle: Effects on expression of IGF-I and GH receptor 1A. J. Endocrinol. 2003, 176:205-217.
4. Butler S.T., Pelton S.H., Butler W.R. Insulin increases 17β-estradiol production by the dominant follicle of the first postpartum follicle wave in dairy cows. Reproduction 2004, 127:537-545.
5. Carter-Su C., Rui L., Herrington J. Role of the tyrosine kinase JAK2 in signal transduction by growth hormone. Pediatr. Nephrol. 2000, 14:550-557.
6. Cummins S.B., Lonergan P., Evans A.C.O., Berry D.P., Evans R.D., Butler S.T. Genetic merit for fertility traits in Holstein cows: I. Production characteristics and reproductive efficiency in a pasture-based system. J. Dairy Sci. 2012, 95:1310-1322.
7. Duan C. Specifying the cellular responses to IGF signals: Roles of IGF-binding proteins. J. Endocrinol. 2002, 175:41-54.
8. Edmonson A.J., Lean I.J., Weaver L.D., Farver T., Webster G. A body condition scoring chart for Holstein dairy cows. J. Dairy Sci. 1989, 72:68-78.
9. Enright W.J., Chapin L.T., Moseley W.M., Zinn S.A., Kamdar M.B., Krabill L.F., Tucker H.A. Effects of infusions of various doses of bovine growth hormone-releasing factor on blood hormones and metabolites in lactating Holstein cows. J. Endocrinol. 1989, 122:671-679.
10. Fenwick M.A., Fitzpatrick R., Kenny David A., Diskin M.G., Patton J., Murphy J., Wathes D.C. Interrelationships between negative energy balance (NEB) and IGF regulation in liver of lactating dairy cows. Domest. Anim. Endocrinol. 2008, 34:31-44.
11. Fenwick M.A., Llewellyn S., Fitzpatrick R., Kenny D.A., Murphy J.J., Patton J., Wathes D.C. Negative energy balance in dairy cows is associated with specific changes in IGF-binding protein expression in the oviduct. Reproduction 2008, 135:63-75.
12. Grala T.M., Lucy M.C., Phyn C.V.C., Sheahan A.J., Lee J.M., Roche J.R. Somatotropic axis and concentrate supplementation in grazing dairy cows of genetically diverse origin. J. Dairy Sci. 2011, 94:303-315.
13. Gross J., van Dorland H.A., Schwarz F.J., Bruckmaier R.M. Endocrine changes and liver mRNA abundance of somatotropic axis and insulin system constituents during negative energy balance at different stages of lactation in dairy cows. J. Dairy Sci. 2011, 94:3484-3494.
14. Guler H.-P., Zapf J., Schmid C., Froesch E.R. Insulin-like growth factors I and II in healthy man. Acta Endocrinol. (Copenh.) 1989, 121:753-758.
15. Horvath C.M. STAT proteins and transcriptional responses to extracellular signals. Trends Biochem. Sci. 2000, 25:496-502.
16. Jiang H., Lucy M.C. Variants of the 5'-untranslated region of the bovine growth hormone receptor mRNA: Isolation, expression and effects on translational efficiency. Gene 2001, 265:45-53.
17. Jones J.I., Clemmons D.R. Insulin-like growth factors and their binding proteins: Biological actions. Endocr. Rev. 1995, 16:3-34.
18. Kobayashi Y., Boyd C.K., Bracken C.J., Lamberson W.R., Keisler D.H., Lucy M.C. Reduced growth hormone receptor (GHR) messenger ribonucleic acid in liver of periparturient cattle is caused by a specific down regulation of GHR 1A that is associated with decreased insulin-like growth factor I. Endocrinology 1999, 140:3947-3954.
19. Le Roith D., Bondy C., Yakar S., Liu J.-L., Butler A. The somatomedin hypothesis: 2001. Endocr. Rev. 2001, 22:53-74.
20. Lucy M.C. Functional differences in the growth hormone and insulin-like growth factor axis in cattle and pigs: Implications for post-partum nutrition and reproduction. Reprod. Domest. Anim. 2008, 43:31-39.
21. Lucy M.C., Jiang H., Kobayashi Y. Changes in the somatotropic axis associated with the initiation of lactation. J. Dairy Sci. 2001, 84:E113-E119. E-Suppl.
22. Lucy M.C., Verkerk G.A., Whyte B.E., Macdonald K.A., Burton L., Cursons R.T., Roche J.R., Holmes C.W. Somatotropic axis components and nutrient partitioning in genetically diverse dairy cows managed under different feed allowances in a pasture system. J. Dairy Sci. 2009, 92:526-539.
23. Lucy M.C., Weber W.J., Baumgard L.H., Seguin B.S., Koenigsfeld A.T., Hansen L.B., Chester-Jones H., Crooker B.A. Reproductive endocrinology of lactating dairy cows selected for increased milk production. J. Anim. Sci. 1998, 76(Suppl. 1):246. (Abstr.).
24. McCarthy S.D., Butler S.T., Patton J., Daly M., Morris D.G., Kenny D.A., Waters S.M. Differences in the expression of genes involved in the somatotropic axis in divergent strains of Holstein-Friesian dairy cows during early and mid lactation. J. Dairy Sci. 2009, 92:5229-5238.
25. Patton J., Kenny D.A., McNamara S., Mee J.F., O'Mara F.P., Diskin M.G., Murphy J.J. Relationships among milk production, energy balance, plasma analytes, and reproduction in Holstein-Friesian cows. J. Dairy Sci. 2007, 90:649-658.
26. Radcliff R.P., McCormack B.L., Crooker B.A., Lucy M.C. Plasma hormones and expression of growth hormone receptor and insulin-like growth factor-I mRNA in hepatic tissue of periparturient dairy cows. J. Dairy Sci. 2003, 86:3920-3926.
27. Rajaram S., Baylink D.J., Mohan S. Insulin-like growth factor-binding proteins in serum and other biological fluids: Regulation and functions. Endocr. Rev. 1997, 18:801-831.
28. Ram P.A., Waxman D.J. SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms. J. Biol. Chem. 1999, 274:35553-35561.
29. Renaville R., Hammadi M., Portetelle D. Role of the somatotropic axis in the mammalian metabolism. Domest. Anim. Endocrinol. 2002, 23:351-360.
30. Rhoads M.L., Meyer J.P., Lamberson W.R., Keisler D.H., Lucy M.C. Uterine and hepatic gene expression in relation to days postpartum, estrus, and pregnancy in postpartum dairy cows. J. Dairy Sci. 2008, 91:140-150.
31. Rhoads R.P., Kim J.W., Leury B.J., Baumgard L.H., Segoale N., Frank S.J., Bauman D.E., Bosclair Y.R. Insulin increases the abundance of the growth hormone receptor in liver and adipose tissue of periparturient dairy cows. J. Nutr. 2004, 134:1020-1027.
32. Rhoads R.P., Kim J.W., Van Amburgh M.E., Ehrhardt R.A., Frank S.J., Boisclair Y.R. Effect of nutrition on the GH responsiveness of liver and adipose tissue in dairy cows. J. Endocrinol. 2007, 195:49-58.
33. Sjögren K., Liu J.-L., Blad K., Skrtic S., Vidal O., Wallenius V., LeRoith D., Törnell J., Isaksson O.G.P., Jansson J.-O., Ohlsson C. Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice. Proc. Natl. Acad. Sci. USA 1999, 96:7088-7092.
34. Smith R.D., Brown B., Ikonomi P., Schechter A.N. Exogenous reference RNA for normalization of real-time quantitative PCR. Biotechniques 2003, 34:88-91.
35. Taylor V.J., Kebreab E., Beever D.E., Mills J., Wathes D.C. Physiological adaptations to milk production that affect the fertility of high yielding dairy cows. Br. Soc. Anim. Sci. Occ. Publ. No. 29 2004, 37-71. Nottingham University Press, Nottingham, UK.
36. Teglund S., McKay C., Schuetz E., van Deursen J.M., Stravopodis D., Wang D., Brown M., Bodner S., Grosveld G., Ihle J.N. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell 1998, 93:841-850.
37. Vandesompele J., De Preter K., Pattaun F., Poppe B., Van Roy N., De Pape A., Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002, 37. Research0034.
38. Veerkamp R.F., Beerda B., van der Lende T. Effects of genetic selection for milk yield on energy balance, levels of hormones, and metabolites in lactating cattle, and possible links to reduced fertility. Livest. Prod. Sci. 2003, 83:257-275.
39. Vicini J.L., Buonomo F.C., Veenhuizen J.J., Miller M.A., Clemmons D.R., Collier R.J. Nutrient balance and stage of lactation affect responses of insulin, insulin-like growth factors I and II, and insulin-like growth factor-binding protein 2 to somatotropin administration in dairy cows. J. Nutr. 1991, 121:1656-1664.
40. Wathes D.C., Bourne N., Cheng Z., Mann G.E., Taylor V.J., Coffey M.P. Multiple correlation analyses of metabolic and endocrine profiles with fertility in primiparous and multiparous cows. J. Dairy Sci. 2007, 90:1310-1325.
41. Wathes D.C., Taylor V.J., Cheng Z., Mann G.E. Follicle growth, corpus luteum function and their effects on embryo development in postpartum dairy cows. Reprod. Suppl. 2003, 61:219-237.
42. Woelfle J., Rotwein P. In vivo regulation of growth hormone-stimulated gene transcription by STAT5b. Am. J. Physiol. Endocrinol. Metab. 2004, 286:E393-E401.