Specifying the cellular responses to IGF signals: Roles of IGF-binding proteins

Journal of Endocrinology

Volumn 175, Issue 1, 2002, Pages 41-54

  Duan, C ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; LIGAND; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL COMMUNICATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HALF LIFE TIME; HORMONAL REGULATION; HUMAN; HUMAN CELL; HYPOGLYCEMIA; LIGAND BINDING; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; STIMULATION; VASCULAR SMOOTH MUSCLE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DIVISION; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; PROTEIN BINDING; RECEPTORS, SOMATOMEDIN; SIGNAL TRANSDUCTION; SOMATOMEDINS;

EID: 0036802186     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1750041     Document Type: Article

References (86)

1. Albrecht-Buehler G 1977 The phagokinetic tracks of 3T3 cells. Cell 11 395-404.
2. Amaar YG, Thompson GR, Linkhart TA, Chen S-T, Baylink DJ & Mohan S 2002 Insulin-like growth factor-binding protein 5 (IGFBP-5) interacts with a four and a half LIM protein 2 (FHL2). Journal of Biological Chemistry 277 12053-12060.
3. Andress DL 1996 Heparin modulates the binding of insulin-like growth factor (IGF) binding protein-5 to a membrane protein in osteoblastic cells. Journal of Biological Chemistry 270 28289-28296.
4. Andress DL 1998 Insulin-like growth factor binding protein-5 (IGFBP-5) stimulates phosphorylation of the IGFBP-5 receptor. American Journal of Physiology 37 E744-E750.
5. Arai T, Parker AJ, Busby WH & Clemmons DR 1994 Heparin, heparan sulfate, and dermatan sulfate regulate formation of the insulin-like growth factor-I and insulin-like growth factor-binding protein complexes. Journal of Biological Chemistry 269 20388-20393.
6. Arai T, Clarke J, Parker AJ, Busby WH, Nam TJ & Clemmons DR 1996 Substitution of specific amino acids in insulin-like growth factor-binding protein-5 alters heparin binding and its change in affinity for IGF-I in response to IGF-I. Journal of Biological Chemistry 271 6099-6106.
7. Bai HZ, Pollman MJ, Inishi Y & Gibbons GH 1999 Regulation of vascular smooth muscle cell apoptosis - modulation of Bad by a phosphatidylinositol 3-kinase-dependent pathway. Circulation Research 85 229-237.
8. Baker J, Liu J-P, Robertson EJ & Efstratiadis A 1993 Role of insulin-like factors in embryonic and postnatal growth. Cell 75 73-82.
9. Baxter RC 2000 Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivities. American Journal of Physiology 278 E967-E976.
10. Bayes-Genis A, Conover CA & Schwartz RS 2000 The insulin-like growth factor axis - a review of atherosclerosis and restenosis. Circulation Research 86 125-130.
11. Boes M, Booth BA, Dake BL, Moser DR & Bar RS 1996 Insulin-like growth factor binding protein production by bovine and human vascular smooth muscle cells: production of insulin-like growth factor binding protein-6 by human smooth muscle. Endocrinology 137 5357-5363.
12. Bornfeldt KE 1996 Intracellular signaling in arterial smooth muscle migration versus proliferation. Trends in Cardiovascular Medicine 6 143-151.
13. Bornfeldt KE, Amqvist HJ & Norstedt G 1990 Regulation of insulin-like growth factor-I gene expression by growth factors in cultured vascular smooth muscle cells. Journal of Endocrinology 125 381-386.
14. Bornfeldt KE, Raines EW, Nakano T, Graves LM, Krebs EG & Ross R 1994 Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation. Journal of Clinical Investigation 93 1266-1274.
15. Busby WH Jr, Nam T-J, Moralez A, Smith C, Jennings M & Clemmons DR 2000 The complement component C1s is the protease that accounts for cleavage of insulin-like growth factor-binding protein-5 in fibroblast medium. Journal of Biological Chemistry 275 37638-37644.
16. Clemmons DR 1985 Variables controlling the secretion of a somatomedin-like peptide by cultured porcine smooth muscle cells. Circulation Research 56 418-426.
17. Clemmons DR 1997 Growth factors and atherosclerosis. Diabetes Review 5 353-364.
18. Clemmons DR 2001 Use of mutagenesis to probe IGF-binding protein structure/function relationships. Endocrine Reviews 22 800-817.
19. Cohen P, Noveral JP, Bhala A, Nunn DJ, Herrick DJ & Grunstein MM 1995 Leukotriene D4 facilitates airway smooth muscle cell proliferation via modulation of the IGF axis. American Journal of Physiology 269 L151-L157.
20. Cohick W, Gockerman A & Clemmons DR 1993 Vascular smooth muscle cells synthesize two forms of insulin-like growth factor binding proteins which are regulated differentially by the insulin-like growth factors. Journal of Cellular Physiology 157 52-60.
21. Cohick W, Gockerman A & Clemmons DR 1995 Regulation of insulin-like growth factor (IGF) binding protein-2 synthesis and degradation by platelet-derived growth factor and the IGFs is enhanced by serum deprivation in vascular smooth muscle cells. Journal of Cellular Physiology 164 187-196.
22. Delafontaine P, Meng XP, Ku L & Du J 1995 Regulation of vascular smooth muscle cell insulin-like growth factor I receptor by phosphorothioate oligonucleotides. Journal of Biological Chemistry 270 14383-14388.
23. Dempsey EC, Stenmark KR, McMurtry IF, O'Brien RF, Voelkel NF & Badesch DB 1990 Insulin-like growth factor I and protein kinase C activation stimulate pulmonary artery smooth muscle cell proliferation through separate but synergistic pathways. Journal of Cell Physiology 144 159-165.
24. Du J & Delafontaine P 1995 Inhibition of vascular smooth muscle cell growth through antisense transcription of a rat insulin-like growth factor I receptor cDNA. Circulation Research 76 963-972.
25. Duan C 1997 Expression and regulation of insulin-like growth factor binding proteins in vascular smooth muscle cells. In Advance in Comparative Endocrinology: Proceedings of the XIIIth International Congress of Comparative Endocrinology, pp 1139-1142. Eds S Kawashima & S Kikuyama. Bologna, Italy: Monduzzi Editore.
26. Duan C 1998 Nutritional and developmental regulation of insulin-like growth factors in fish. Journal of Nutrition 128 306S-314S.
27. Duan C & Clemmons DR 1998 Differential expression and opposing biological effects of insulin-like growth factor binding protein-4 and -5 in vascular smooth muscle cells. Journal of Biological Chemistry 273 16836-16842.
28. Duan C, Hawes SB, Prevette T & Clemmons DR 1996 Insulin-like growth factor-I (IGF-I) regulates IGF-binding protein-5 synthesis through transcriptional activation of the gene in aortic smooth muscle cells. Journal of Biological Chemistry 272 4280-4288.
29. Duan C, Ding J, Li Q, Tsai W & Pozias K 1999a Insulin-like growth factor (IGF) binding protein-2 is a growth inhibitory protein highly conserved in zebrafish. PNAS 96 15274-15279.
30. Duan C, Limatta MB & Bottum OL 1999b Insulin-like growth factor (IGF)-I regulates IGF binding protein-5 expression through the phosphatidylinositol-3-kinase, PKB/Akt and p70 S6 kinase signaling pathway. Journal of Biological Chemistry 274 37147-37153.
31. Duan C, Bauchat JR. & Hsieh T 2000 Phosphatidylinositol 3-kinase is required for IGF-I-induced vascular smooth muscle cell proliferation and migration. Circulation Research 86 15-23.
32. Duan C, Li S & Gordon RE 2002 Identification of heparan sulfate proteoglycan as a 'cellular receptor' for IGFBP-5. ENDO 2002 Meeting, San Francisco, CA, 19-22 June, 2002. P3-237.
33. Esko JD, Steward TE & Taylor WH 1985 Animal-cell mutants defective in glycosaminoglycan biosynthesis. PNAS 82 3197-3201.
34. Esko JD, Elgavish A, Prasthofer T, Taylor WH & Weinke JL 1986 Sulfate transport-deficient mutants of Chinese hamster ovary cells. Sulfation of glycosaminoglycans dependent on cysteine. Journal of Biological Chemistry 261 15725-15733.
35. Esko JD, Weinke JL, Taylor WH, Ekborg G, Roden L, Anantharamaiah G & Gawish A 1987 Inhibition of chondroitin and heparan sulfate biosynthesis in Chinese hamster ovary cell mutants defective in galactosyltransferase I. Journal of Biological Chemistry 262 12189-12195.
36. Francis GL, Ross M, Ballard FJ, Milner SJ, Senn C, McNeil KA, Wallace JC, King R & Wells JRE 1992 Novel recombinant fusion protein analogs of insulin-like growth factor (IGF)-I indicate the relative importance of IGF-binding protein and receptor-binding for enhanced biological potency. Journal of Molecular Endocrinology 8 213-223.
37. Giannella-Neto D, Kamyar A, Sharifi B, Pirola CJ, Kupfer J, Rosenfeld RG, Forrester JS & Fagin JA 1992 Platelet-derived growth factor isoforms decrease in rat vascular smooth muscle cells and selectively stimulate the biosynthesis of insulin-like growth factor binding protein 4. Circulation Research 71 646-656.
38. Gockerman A, Prevette T, Jones JI & Clemmons DR 1995 Insulin-like growth factor binding protein-2 inhibits smooth muscle cell migration response to IGF-I. Endocrinology 136 4168-4173.
39. Graves LM, Bornfeldt KE, Sidhu JS, Argast GM, Raines FW, Ross R, Leslie CC & Krebs EG 1996 Platelet-derived growth factor stimulates protein kinase A through a mitogen-activated protein kinase-dependent pathway in human arterial smooth muscle cells. Journal of Biological Chemistry 272 505-511.
40. Hedin U, Bottger BA, Forsberg E, Johansson S & Thyberg J 1988 Diverse effects of fibronectin and laminin on phenotypic properties of cultured arterial smooth muscle cells. Journal of Cell Biology 107 307-319.
41. Hsieh T, Rosario C & Duan C 2000 IGFBP-5 regulates cell motility through an IGF-independent mechanism that involves nuclear localization. ENDO 2000 Meeting, June, 2000. Toronto, Canada.
42. Hwa V, Oh Y & Rosenfeld RG 1999 The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocrine Reviews 20 761-787.
43. Imai Y & Clemmons DR 1999 Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascular smooth muscle cell migration and deoxyribonucleic acid synthesis by insulin-like growth factor-I. Endocrinology 140 4228-4235.
44. Imai Y, Busby WH, Clark JB, Horvitz G, Rees C & Clemmons DR 1997 Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture. Journal of Clinical Investigation 100 2596-2605.
45. Jaques G, Noll K, Wegmann B, Witten S, Kogan E, Radulescu R & Havemann K 1997 Nuclear localization of insulin-like growth factor binding protein 3 in a lung cancer cell line. Endocrinology 138 1767-1770.
46. Jones IJ, Gockerman A, Busby WH & Clemmons DR 1993 Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I. Journal of Cell Biology 121 679-687.
47. Kamyar A, Pirola CJ, Wang, HM, Sharifi B, Mohan S, Forrester JS & Fagin JA 1994 Expression and insulin-like growth factor-dependent proteolysis of insulin-like growth factor-binding protein-4 are regulated by cell confluence in vascular smooth muscle cells. Circulation Research 74 576-585.
48. Koyama H, Nishizawa Y, Hosoi M, Kogawa K, Shioi A & Morii H 1996 The fumagillin analogue TNP-470 inhibits DNA synthesis of vascular smooth muscle cells stimulated by platelet-derived growth factor and insulin-like growth factor-I - possible involvement of cyclin-dependent kinase 2. Circulation Research 79 757-764.
49. LeRoith D, Bondy C, Yakar S, Liu J-L & Butler A 2001 The somatomedin hypothesis: 2001. Endocrine Reviews 22 53-74.
50. Li S & Duan C 2001 Basic and hydrophobic residues in the nuclear localization and ligand binding domains are important for nuclear import of IGFBP-5. ENDO 2001 Meeting, Denver, CO, 20-23 June, 2001. OR38-4.
51. Li W, Fawcett J, Widmer HR, Fielder PJ, Rabkin R & Keller G-A 1997 Nuclear transport of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in opossum kidney cells. Endocrinology 138 1763-1766.
52. Liu P, Baker J, Perkins AS, Robertson EJ & Efstratiadis A 1993 Mice carrying null mutations of the genes encoding insulin-like growth factor I (IGF-1) and type I IGF receptor (IGFIR,). Cell 75 59-72.
53. Maures T & Duan C 2002 Structure, developmental expression, and physiological regulation of zebrafish insulin-like growth factor binding protein-1. Endocrinology 143 2722-2731.
54. Miyakoshi N, Richman C, Kasukawa Y, Linkhart TA, Baylink DJ & Mohan S 2001 Evidence that IGF-binding protein-5 functions as a growth factor. Journal of Clinical Investigation 107 73-81.
55. Motomura N, Lou H, Maurice P & Foegh ML 1997 Acceleration of arteriosclerosis of the rat aorta allograft by insulin growth factor-I. Transplantation 63 932-936.
56. Muniyappa R, Walsh MF, Rangi JS, Zayas RM, Standley PR, Ram JL & Sowers JR 1997 Insulin like growth factor I increases vascular smooth muscle nitric oxide production. Life Sciences 61 925-931.
57. Newton A 1995 Protein kinase C: structure, function, and regulation. Journal of Biological Chemistry 270 28495-28498.
58. Parker A, Gockerman A, Busby WH & Clemmons DR 1995 Properties of an insulin-like growth factor-binding protein-4 protease that is secreted by smooth muscle cells. Endocrinology 136 2470-2476.
59. Parker A, Clarke JB, Busby WH Jr & Clemmons DR 1996 Identification of the extracellular matrix binding sites for insulin-like growth factor-binding protein 5. Journal of Biological Chemistry 271 13523-13529.
60. Parker A, Rees C, Clarke JB, Busby WH Jr & Clemmons DR 1998 Binding of insulin-like growth factor (IGF)-binding protein-5 to smooth muscle cell extracellular matrix is a major determinant of the cellular response to IGF-I. Molecular Biology of the Cell 9 2383-2392.
61. Parrizas M, Saltiel AR & LeRoith D 1997 Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways. Journal of Biological Chemistry 272 154-161.
62. Patel VA, Zhang QJ, Siddle K, Soos MA, Goddard M, Weissberg PL & Bennett MR 2001 Defect in insulin-like growth factor-I survival mechanism in atheroselerotic plaque-derived vascular smooth muscle cells is mediated by reduced surface binding and signaling. Circulation Research 88 895-902.
63. Pavlovic-Surjancev B, Cahill BL & Perlman RL 1992 Nicotinic agonists, phorbol esters, and growth factors activate 2 extracellular signal-regulated kinases, ERK 1 and ERK2, in bovine chromaffin cells. Journal of Neurochemistry 59 2134-2140.
64. Pera EM, Wessely O, Li SY & De Robertis EM 2001 Neural, and head induction by insulin-like growth factor signals. Developmental Cell 1 655-665.
65. Pukac L, Huangpu J & Karnovsky MJ 1998 Platelet-derived growth factor-BB, insulin-like growth factor-I, and phorbol ester activate different signaling pathways for stimulation of vascular smooth muscle cell migration. Experimental Cell Research 242 548-560.
66. Radulescu R 1995 From insulin, retinoblastoma protein and the insulin receptor to a new model on growth factor specificity: the nucleocrine pathway. Journal of Endocrinology 146 365-368.
67. Ren J, Sowers JR, Natavio M & Brown RA 1999 Influence of age on inotropic response to insulin and insulin-like growth factor I in spontaneously hypertensive rats: role of nitric oxide. Proceedings of the Society for Experimental Biology and Medicine 221 46-52.
68. Richard-Parpaillon L, Heligon C, Chesnel F, Boujard D & Philpott A 2002 The IGF pathway regulates head formation by inhibiting Wnt signaling in Xenopus. Developmental Biology 244 407-417.
69. Ross R 1993 The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362 801-809.
70. Schedlich LJ, Young TF, Firth SM & Baxter RC 1998 Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 share a common nuclear transport pathway in T47D human breast carcinoma cells. Journal of Biological Chemistry 273 18347-18352.
71. Schedlich LJ, Le Page SL, Firth SM, Briggs LJ, Jans DA & Baxter RC 2000 Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin subunit. Journal of Biological Chemistry 275 23462-23470.
72. Schneider MR, Wolf E, Hoeflich A & Lahm H 2002 IGF-binding protein-5: flexible player in the IGF system and effector on its own. Journal of Endocrinology 172 423-440.
73. Sowers JR 1996 Effects of insulin and IGF-I on vascular smooth muscle glucose and cation metabolism. Diabetes 45 S47-S51.
74. Sowers JR 1997 Insulin and insulin-like growth factor in normal and pathological cardiovascular physiology. Hypertension 29 691-699.
75. Summerford C & Samuski RJ 1998 Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. Journal of Virology 72 1438-1445.
76. Takagi Y, Kashiwagi A, Tanaka Y, Maegawa H & Shigeta Y 1995 Insulin-specific activation of S6 kinase and IRS desensitization in cultured rat vascular smooth muscle cells. Atherosclerosis 113 19-27.
77. Thommes KB, Hoppe J, Vetter H & Sachinidis A 1996 The synergistic effect of PDGF-AA and IGF-I on SMC proliferation might be explained by the differential activation of their intracellular signaling pathways. Experimental Cell Research 226 59-66.
78. Tyagi M, Rusnati M, Presta M & Giacca M 2001 Internalization of HIV-1 Tat requires cell surface heparan sulfate proteoglycans. Journal of Biological Chemistry 276 3254-3261.
79. Ververis JJ, Ku L & Delafontaine P 1993 Regulation of insulin-like growth factor I receptors on vascular smooth muscle cells by growth factors and phorbol esters. Circulation Research 72 1285-1292.
80. Vivès E, Brodin P & Lebleu B 1997 A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. Journal of Biological Chemistry 272 16010-16017.
81. Walsh MF, Barazi M, Pete G, Muniyappa R, Dunbar JC & Sowers JR 1996 Insulin-like growth factor I diminishes in vivo and in vitro vascular contractility: role of vascular nitric oxide. Endocrinology 137 1798-1803.
82. Wang JW, Niu W, Nikiforov Y, Naito S, Chernausek S, Witte D, LeRoith D, Strauch A & Fagin JA 1997 Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice. Journal of Clinical Investigation 100 1425-1439.
83. Xu Q & Duan C 2001 Distinct C-domains detennine the differential subcellular localization and different biological actions of IGFBP-4 and IGFBP-5 in smooth muscle cells. ENDO 2001 Meeting, Denver, CO, 20-23 June, 2001. OR5-4.
84. Yano K, Bauchat JR, Limatta M, Clemmons DR & Duan C 1999 Down-regulation of protein kinase C inhibits insulin-like growth factor-I-induced vascular smooth muscle cell proliferation, migration and gene expression. Endocrinology 140 4622-4632.
85. Zaina S, Pettersson L, Ahrén B, Brånén L, Hassan AB, Lindhol M, Mattsson R, Thyberg J & Nilsson J 2002 Insulin-like growth factor II plays a central role in atherosclerosis in a mouse model. Journal of Biological Chemistry 277 4505-4511.
86. Zheng B, Duan C & Clemmons DR 1998 The effect of extracellular matrix proteins on porcine smooth muscle cell insulin-like growth factor (IGF) binding protein-5 synthesis and responsiveness to IGF-I. Journal of Biological Chemistry 273 8994-9000.