Mice expressing a human K ATP channel mutation have altered channel ATP sensitivity but no cardiac abnormalities

Diabetologia

Volumn 55, Issue 4, 2012, Pages 1195-1204

  Clark, R ^a,b   Mannikko R ^a,b,c   Stuckey, D J ^a,d   Iberl, M ^a,b   Clarke, K ^a,b   Ashcroft, F M ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

ATP sensitive potassium channel; Cardiac ischaemia; Kir6.2; MRI; Sulfonylurea receptor

Indexed keywords

DOBUTAMINE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL WALL THICKNESS; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CONTROLLED STUDY; DIABETES MELLITUS; END DIASTOLIC VOLUME; ENZYME INHIBITION; EXERCISE TEST; GAIN OF FUNCTION MUTATION; GROWTH RETARDATION; HEART EJECTION FRACTION; HEART FUNCTION; HEART MUSCLE; HEART MUSCLE CELL; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HEART VENTRICLE ENDSYSTOLIC VOLUME; HEART VOLUME; IN VIVO STUDY; INTERMEDIATE DEND SYNDROME; MENTAL DISEASE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATCH CLAMP; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; HEART; MICE; MUTATION; MYOCYTES, CARDIAC; POTASSIUM CHANNELS, INWARDLY RECTIFYING;

EID: 84862578542     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2428-6     Document Type: Article

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