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Volumn 302, Issue 12, 2012, Pages

The direct profibrotic and indirect immune antifibrotic balance of blocking the cannabinoid 2 receptor

Author keywords

Hepatic stellate cells; Liver injury; Lymphocytes

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; CANNABINOID 2 RECEPTOR; CARBON TETRACHLORIDE; CD4 ANTIGEN; CD8 ANTIGEN;

EID: 84862540923     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00191.2011     Document Type: Article
Times cited : (9)

References (32)
  • 1
    • 80053571291 scopus 로고    scopus 로고
    • Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease
    • Basu SB, Dittel N. Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease. Immunol Res 51: 2638, 2011.
    • (2011) Immunol Res , vol.51 , pp. 2638
    • Basu, S.B.1    Dittel, N.2
  • 7
    • 0034808310 scopus 로고    scopus 로고
    • History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells
    • Geerts A. History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells. Semin Liver Dis 21: 311-335, 2001.
    • (2001) Semin Liver Dis , vol.21 , pp. 311-335
    • Geerts, A.1
  • 8
    • 0035200752 scopus 로고    scopus 로고
    • Formation of normal desmin intermediate filaments in mouse hepatic stellate cells requires vimentin
    • Geerts A, Eliasson C, Niki T, Wielant F, Pekny M. Formation of normal desmin intermediate filaments in mouse hepatic stellate cells requires vimentin. Hepatology 33: 177-188, 2001.
    • (2001) Hepatology , vol.33 , pp. 177-188
    • Geerts, A.1    Eliasson, C.2    Niki, T.3    Wielant, F.4    Pekny, M.5
  • 11
    • 52949141093 scopus 로고    scopus 로고
    • Endocannabinoids in liver disease and hepatic encephalopathy
    • Magen I, Avraham Y, Berry E, Mechoulam R. Endocannabinoids in liver disease and hepatic encephalopathy. Curr Pharm Des 14: 2362-2369, 2008.
    • (2008) Curr Pharm Des , vol.14 , pp. 2362-2369
    • Magen, I.1    Avraham, Y.2    Berry, E.3    Mechoulam, R.4
  • 12
    • 58849106783 scopus 로고    scopus 로고
    • Cannabinoid receptors as therapeutic targets in the management of liver diseases
    • Mallat A, Lotersztajn S. Cannabinoid receptors as therapeutic targets in the management of liver diseases. Drug News Perspect 21: 363-368, 2008.
    • (2008) Drug News Perspect , vol.21 , pp. 363-368
    • Mallat, A.1    Lotersztajn, S.2
  • 14
    • 0031010128 scopus 로고    scopus 로고
    • Bone marrow transplantation in acid sphingomyelinase-deficient mice: Engraftment and cell migration into the brain as a function of radiation, age, and phenotype
    • Miranda SR, Erlich S, Visser JW, Gatt S, Dagan A, Friedrich VL, Schuchman EH. Bone marrow transplantation in acid sphingomyelinase-deficient mice: engraftment and cell migration into the brain as a function of radiation, age, and phenotype. Blood 90: 444-452, 1997.
    • (1997) Blood , vol.90 , pp. 444-452
    • Miranda, S.R.1    Erlich, S.2    Visser, J.W.3    Gatt, S.4    Dagan, A.5    Friedrich, V.L.6    Schuchman, E.H.7
  • 16
    • 34247171754 scopus 로고    scopus 로고
    • Lymphocyte-hepatic stellate cell proximity suggests a direct interaction
    • Muhanna N, Horani A, Doron S, Safadi R. Lymphocyte-hepatic stellate cell proximity suggests a direct interaction. Clin Exp Immunol 148: 338-347, 2007.
    • (2007) Clin Exp Immunol , vol.148 , pp. 338-347
    • Muhanna, N.1    Horani, A.2    Doron, S.3    Safadi, R.4
  • 17
    • 51349102719 scopus 로고    scopus 로고
    • Activation of hepatic stellate cells following phagocytosis of lymphocytes-a novel pathway of fibrogenesis
    • Muhanna N, Doron S, Wald O, Horani A, Eid A, Pappo O, Friedman SL, Safadi R. Activation of hepatic stellate cells following phagocytosis of lymphocytes-a novel pathway of fibrogenesis. Hepatology 48: 963-977, 2008.
    • (2008) Hepatology , vol.48 , pp. 963-977
    • Muhanna, N.1    Doron, S.2    Wald, O.3    Horani, A.4    Eid, A.5    Pappo, O.6    Friedman, S.L.7    Safadi, R.8
  • 18
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S, Thomas KL, Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 365: 61-65, 1993.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 21
    • 33748703859 scopus 로고    scopus 로고
    • The endocannabinoid system as an emerging target of pharmacotherapy
    • Pacher P, Batkai S, Kunos G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 58: 389-462, 2006.
    • (2006) Pharmacol Rev , vol.58 , pp. 389-462
    • Pacher, P.1    Batkai, S.2    Kunos, G.3
  • 22
    • 63449105700 scopus 로고    scopus 로고
    • Role of cannabinoids in chronic liver diseases
    • Parfieniuk A, Flisiak R. Role of cannabinoids in chronic liver diseases. World J Gastroenterol 14: 6109-6114, 2008.
    • (2008) World J Gastroenterol , vol.14 , pp. 6109-6114
    • Parfieniuk, A.1    Flisiak, R.2
  • 24
    • 4444289142 scopus 로고    scopus 로고
    • Immune stimulation of hepatic fibrogenesis by CD8 lymphocytes and its attenuation by transgenic interleukin from hepatocytes
    • Safadi R, Ohta M, Alvarez CE, Fiel I, Bansal M, Mehal W, Friedman SL. Immune stimulation of hepatic fibrogenesis by CD8 lymphocytes and its attenuation by transgenic interleukin from hepatocytes. Gastroenterology 127: 870-882, 2004.
    • (2004) Gastroenterology , vol.127 , pp. 870-882
    • Safadi, R.1    Ohta, M.2    Alvarez, C.E.3    Fiel, I.4    Bansal, M.5    Mehal, W.6    Friedman, S.L.7
  • 28
    • 33745195042 scopus 로고    scopus 로고
    • Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand
    • Sugiura T, Kishimoto S, Oka S, Gokoh M. Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand. Prog Lipid Res 45: 405-446, 2006.
    • (2006) Prog Lipid Res , vol.45 , pp. 405-446
    • Sugiura, T.1    Kishimoto, S.2    Oka, S.3    Gokoh, M.4
  • 30
    • 33745003240 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor antagonism: A new strategy for the treatment of liver fibrosis
    • Teixeira-Clerc F, Julien B, Grenard P, et al. CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis. Nat Med 12: 671-676, 2006.
    • (2006) Nat Med , vol.12 , pp. 671-676
    • Teixeira-Clerc, F.1    Julien, B.2    Grenard, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.