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Volumn 10, Issue 6, 2012, Pages 673-676

Development of Noxa-like BH3 mimetics for apoptosis-based therapeutic strategy in chronic lymphocytic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; BORTEZOMIB; DASATINIB; FLAVOPIRIDOL; FLUDARABINE; GIMERACIL PLUS OTERACIL POTASSIUM PLUS TEGAFUR; GOSSYPOL; GOSSYPOL DERIVATIVE; ISOSORBIDE; NAVITOCLAX; OBATOCLAX; PROTEIN BCL 2; PROTEIN MCL 1; ROSCOVITINE; TW 37; UNCLASSIFIED DRUG;

EID: 84862516953     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-12-0015     Document Type: Review
Times cited : (12)

References (31)
  • 2
    • 70349562920 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of CLL: Novel therapeutic approaches
    • Pleyer L, Egle A, Hartmann TN, Greil R. Molecular and cellular mechanisms of CLL: novel therapeutic approaches. Nat Rev Clin Oncol 2009;6:405-18.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 405-418
    • Pleyer, L.1    Egle, A.2    Hartmann, T.N.3    Greil, R.4
  • 3
    • 77956266018 scopus 로고    scopus 로고
    • Chemoimmunotherapy of chronic lymphocytic leukemia
    • Tam CS, Keating MJ. Chemoimmunotherapy of chronic lymphocytic leukemia. Nat Rev Clin Oncol 2010;7:521-32.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 521-532
    • Tam, C.S.1    Keating, M.J.2
  • 4
    • 77952952903 scopus 로고    scopus 로고
    • The role of Bcl-2 family proteins in chronic lymphocytic leukaemia
    • Buggins AGS, Pepper CJ. The role of Bcl-2 family proteins in chronic lymphocytic leukaemia. Leuk Res 2010;34:837-42.
    • (2010) Leuk Res , vol.34 , pp. 837-842
    • Buggins, A.G.S.1    Pepper, C.J.2
  • 5
    • 78049426652 scopus 로고    scopus 로고
    • Inflammation and survival pathways: Chronic lymphocytic leukemia as a model system
    • Chen LS, Balakrishnan K, Gandhi V. Inflammation and survival pathways: chronic lymphocytic leukemia as a model system. Biochem Pharmacol 2010;80:1936-45.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1936-1945
    • Chen, L.S.1    Balakrishnan, K.2    Gandhi, V.3
  • 6
    • 55749105701 scopus 로고    scopus 로고
    • Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers
    • Pepper C, Lin TT, Pratt G, Hewamana S, Brennan P, Hiller L, et al. Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers. Blood 2008;112:3807-17.
    • (2008) Blood , vol.112 , pp. 3807-3817
    • Pepper, C.1    Lin, T.T.2    Pratt, G.3    Hewamana, S.4    Brennan, P.5    Hiller, L.6
  • 7
    • 60249088881 scopus 로고    scopus 로고
    • Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab
    • Awan FT, Kay NE, Davis ME, Wu W, Geyer SM, Leung N, et al. Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab. Blood 2009;113:535-7.
    • (2009) Blood , vol.113 , pp. 535-537
    • Awan, F.T.1    Kay, N.E.2    Davis, M.E.3    Wu, W.4    Geyer, S.M.5    Leung, N.6
  • 9
    • 34247511009 scopus 로고    scopus 로고
    • Mcl-1 is a relevant therapeutic target in acute and chronic lymphoid malignancies: Downregulation enhances rituximab-mediated apoptosis and complement-dependent cytotoxicity
    • Hussain SRA, Cheney CM, Johnson AJ, Lin TS, Grever MR, Caligiuri MA, et al. Mcl-1 is a relevant therapeutic target in acute and chronic lymphoid malignancies: Downregulation enhances rituximab-mediated apoptosis and complement-dependent cytotoxicity. Clin Cancer Res 2007;13:2144.
    • (2007) Clin Cancer Res , vol.13 , pp. 2144
    • Hussain, S.R.A.1    Cheney, C.M.2    Johnson, A.J.3    Lin, T.S.4    Grever, M.R.5    Caligiuri, M.A.6
  • 10
    • 77955752225 scopus 로고    scopus 로고
    • Strategy to induce apoptosis and circumvent resistance in chronic lymphocytic leukaemia
    • Chen R, Plunkett W. Strategy to induce apoptosis and circumvent resistance in chronic lymphocytic leukaemia. Best Pract Res Clin Haematol 2010;23:155-66.
    • (2010) Best Pract Res Clin Haematol , vol.23 , pp. 155-166
    • Chen, R.1    Plunkett, W.2
  • 12
    • 42349095198 scopus 로고    scopus 로고
    • Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells
    • DOI 10.1038/leu.2008.1, PII LEU20081
    • Inoue S, Walewska R, Dyer MJS, Cohen GM. Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells. Leukemia 2008;22:819-25. (Pubitemid 351552631)
    • (2008) Leukemia , vol.22 , Issue.4 , pp. 819-825
    • Inoue, S.1    Walewska, R.2    Dyer, M.J.S.3    Cohen, G.M.4
  • 13
    • 77958198168 scopus 로고    scopus 로고
    • AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells
    • Santidrián AF, González-Gironès DM, Iglesias-Serret D, Coll-Mulet L, Cosialls AM, de Frias M, et al. AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells. Blood 2010;116: 3023-32.
    • (2010) Blood , vol.116 , pp. 3023-3032
    • Santidrián, A.F.1    González-Gironès, D.M.2    Iglesias-Serret, D.3    Coll-Mulet, L.4    Cosialls, A.M.5    De Frias, M.6
  • 14
    • 77956863324 scopus 로고    scopus 로고
    • Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells
    • Baou M, Kohlhaas SL, Butterworth M, Vogler M, Dinsdale D, Walewska R, et al. Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells. Haematologica 2010;95:1510-8.
    • (2010) Haematologica , vol.95 , pp. 1510-1518
    • Baou, M.1    Kohlhaas, S.L.2    Butterworth, M.3    Vogler, M.4    Dinsdale, D.5    Walewska, R.6
  • 15
    • 84455193932 scopus 로고    scopus 로고
    • Hyperforin induces apoptosis of chronic lymphocytic leukemia cells through upregulation of the BH3-only protein Noxa
    • Zaher M, Tang R, Bombarda I, Merhi F, Bauvois B, Billard C. Hyperforin induces apoptosis of chronic lymphocytic leukemia cells through upregulation of the BH3-only protein Noxa. Int J Oncol 2012;40: 269-76.
    • (2012) Int J Oncol , vol.40 , pp. 269-276
    • Zaher, M.1    Tang, R.2    Bombarda, I.3    Merhi, F.4    Bauvois, B.5    Billard, C.6
  • 17
    • 33846556759 scopus 로고    scopus 로고
    • Regulation of the proapoptotic BH3-only protein BIM by glucocorticoids, survival signals and proteasome in chronic lymphocytic leukemia cells
    • DOI 10.1038/sj.leu.2404483, PII 2404483
    • Iglesias-Serret D, de Frias M, Santidrián AF, Coll-Mulet L, Cosialls AM, Barragán M, et al. Regulation of the proapoptotic BH3-only protein BIM by glucocorticoids, survival signals and proteasome in chronic lymphocytic leukemia cells. Leukemia 2007;21:281-7. (Pubitemid 46158121)
    • (2007) Leukemia , vol.21 , Issue.2 , pp. 281-287
    • Iglesias-Serret, D.1    De Frias, M.2    Santidrian, A.F.3    Coll-Mulet, L.4    Cosialls, A.M.5    Barragan, M.6    Domingo, A.7    Gil, J.8    Pons, G.9
  • 20
    • 33747875167 scopus 로고    scopus 로고
    • Phase II study of single-agent bortezomib for the treatment of patients with fludarabine-refractory B-cell chronic lymphocytic leukemia
    • DOI 10.1002/cncr.22097
    • Faderl S, Rai K, Gribben J, Byrd JC, Flinn IW, O'Brien S, et al. Phase II study of single-agent bortezomib for the treatment of patients with fludarabine-refractory B-cell chronic lymphocytic leukemia. Cancer 2006;107:916-24. (Pubitemid 44291139)
    • (2006) Cancer , vol.107 , Issue.5 , pp. 916-924
    • Faderl, S.1    Rai, K.2    Gribben, J.3    Byrd, J.C.4    Flinn, I.W.5    O'Brien, S.6    Sheng, S.7    Esseltine, D.-L.8    Keating, M.J.9
  • 21
    • 20144388905 scopus 로고    scopus 로고
    • Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis
    • Nencioni A, Hua F, Dillon CP, Yokoo R, Scheiermann C, Cardone MH, et al. Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis. Blood 2005;105:3255-62.
    • (2005) Blood , vol.105 , pp. 3255-3262
    • Nencioni, A.1    Hua, F.2    Dillon, C.P.3    Yokoo, R.4    Scheiermann, C.5    Cardone, M.H.6
  • 22
    • 0036710477 scopus 로고    scopus 로고
    • Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs
    • DOI 10.1016/S0006-2952(02)01148-6, PII S0006295202011486
    • Baell JB, Huang DCS. Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs. Biochem Pharmacol 2002;64:851-63. (Pubitemid 35232259)
    • (2002) Biochemical Pharmacology , vol.64 , Issue.5-6 , pp. 851-863
    • Baell, J.B.1    Huang, D.C.S.2
  • 26
    • 83055173306 scopus 로고    scopus 로고
    • Overcoming blocks in apoptosis with BH3-mimetic therapy in haematological malignancies
    • Khaw SL, Huang DCS, Roberts AW. Overcoming blocks in apoptosis with BH3-mimetic therapy in haematological malignancies. Pathology 2011;43:525-35.
    • (2011) Pathology , vol.43 , pp. 525-535
    • Khaw, S.L.1    Huang, D.C.S.2    Roberts, A.W.3
  • 27
    • 79960119761 scopus 로고    scopus 로고
    • Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and upregulating BH3-only protein NOXA
    • Albershardt TC, Salerni BL, Soderquist RS, Bates DJP, Pletnev AA, Kisselev AF, et al. Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and upregulating BH3-only protein NOXA. J Biol Chem 2011;286:24882-95.
    • (2011) J Biol Chem , vol.286 , pp. 24882-24895
    • Albershardt, T.C.1    Salerni, B.L.2    Soderquist, R.S.3    Bates, D.J.P.4    Pletnev, A.A.5    Kisselev, A.F.6
  • 28
    • 77955061203 scopus 로고    scopus 로고
    • Apoptosis of B-cell chronic lymphocytic leukemia cells induced by a novel BH3 peptidomimetic
    • Ghiotto F, Fais F, Tenca C, Tomati V, Morabito F, Casciaro S, et al. Apoptosis of B-cell chronic lymphocytic leukemia cells induced by a novel BH3 peptidomimetic. Cancer Biol Ther 2009;8: 263-71.
    • (2009) Cancer Biol Ther , vol.8 , pp. 263-271
    • Ghiotto, F.1    Fais, F.2    Tenca, C.3    Tomati, V.4    Morabito, F.5    Casciaro, S.6
  • 31
    • 77955891885 scopus 로고    scopus 로고
    • The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer
    • Stewart ML, Fire E, Keating AE, Walensky LD. The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer. Nat Chem Biol 2010;6:595-601.
    • (2010) Nat Chem Biol , vol.6 , pp. 595-601
    • Stewart, M.L.1    Fire, E.2    Keating, A.E.3    Walensky, L.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.