Analysis of current research addressing complementary use of life-cycle assessment and risk assessment for engineered nanomaterials: Have lessons been learned from previous experience with chemicals?

Journal of Nanoparticle Research

Volumn 14, Issue 7, 2012, Pages

  Grieger, Khara D ^a,d   Laurent, Alexis ^a   Miseljic, Mirko ^a   Christensen, Frans ^b,c   Baun, Anders ^a   Olsen, Stig I ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b JOINT RESEARCH CENTRE   (Italy)

^c COWI A/S ^*  (Denmark)

^d RTI INTERNATIONAL   (United States)

Author keywords

Chemicals; Engineered nanomaterials; Life cycle assessment; Risk assessment

Indexed keywords

ARTIFICIAL LIFE; CHEMICALS; ENVIRONMENTAL IMPACT; HEALTH RISKS; NANOSTRUCTURED MATERIALS; RISK ASSESSMENT;

ASSESSMENT PROCEDURE; ENGINEERED NANOMATERIALS; LIFE CYCLE ASSESSMENT (LCA); LIFE CYCLE PERSPECTIVES; LITERATURE REVIEWS; RESEARCH EFFORTS; SCIENTIFIC RESEARCHES; SEPARATE ANALYSIS;

LIFE CYCLE;

NANOMATERIAL;

ARTICLE; HUMAN; INFORMATION RETRIEVAL; LIFE CYCLE ASSESSMENT; NANOENGINEERING; PRIORITY JOURNAL; RISK ASSESSMENT;

EID: 84862503248     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-012-0958-6     Document Type: Article

References (114)

1. Aitken RA, Bassan A, Friedrichs S et al. (2011) Specific advice on exposure assessment and hazard/risk characterisation for nanomaterials under REACH (RIP-oN 3). Final Project Report, RNC/RIP-oN3/FPR/1/FINAL. http://ec.europa.eu/environment/chemicals/nanotech/pdf/report-ripon3.pdf. Accessed 9 Nov 2011
2. Anastas P, Davis M (2010) August 2010 BOSC nanomaterial case studies workshop review letter report. US Environmental Protection Agency Office of Research and Development, Board of Scientific Counselors (BOSC). http://www.epa.gov/osp/bosc/pdf/nano1008rpt.pdf. Accessed 9 Nov 2011
3. K Aschberger HJ Johnston V Stone RJ Aitken CL Tran SM Hankin SAK Peters FM Christensen 2010 Review of carbon nanotubes toxicity and exposure-appraisal of human health risk assessment based on open literature Crit Rev Toxicol 40 759 790 10.3109/10408444.2010.506638 1:CAS:528:DC%2BC3cXhtFylsbnP
4. K Aschberger HJ Johnston V Stone RJ Aitken CL Tran SM Hankin SAK Peters FM Christensen 2010 Review of fullerene toxicity and exposure-a human health risk assessment appraisal based on open literature Regul Toxicol Pharmacol 58 455 473 10.1016/j.yrtph.2010.08.017 1:CAS:528:DC%2BC3cXhsFWqur3N
5. DR Baer DJ Gaspar P Nachimuthu SD Techane DG Castner 2010 Application of surface chemical analysis tools for characterization of nanoparticles Anal Bioanal Chem 396 100 983
6. J Bare 2006 Risk assessment and life-cycle impact assessment (LCIA) for human health cancerous and noncancerous emissions: integrated and complementary with consistency within the USEPA Hum Ecol Risk Assess 12 493 509 10.1080/10807030600561683 1:CAS:528:DC%2BD28Xntl2nsb8%3D
7. C Bauer J Buchgeister R Hischier WR Poganietz L Schebek J Warsen 2008 Towards a framework for life-cycle thinking in the assessment of nanotechnology J Clean Prod 16 910 926 10.1016/j.jclepro.2007.04.022
8. A Baun NB Hartmann K Grieger SF Hansen 2009 Setting the limits for engineered nanoparticles in European surface waters J Environ Monit 11 1774 1781 10.1039/b909730a 1:CAS:528:DC%2BD1MXht1ags7nN
9. Biomedtalk (2009) Public discussion on the FP7 project 228536 - NEPHH. http://www.biomedtalk.com/forumdisplay.php?f=631. Accessed 17 June 2012
10. DR Boverhof RM David 2010 Nanomaterial characterization: considerations and needs for hazard assessment and safety evaluation Anal Bioanal Chem 396 953 961 10.1007/s00216-009-3103-3 1:CAS:528:DC%2BD1MXhtFaqtL7E
11. Bühler P (2010) Media releases: Bühler Partec's risk management system certified. http://www.buhlergroup.com/global/en/about-buhler/media/ media-releases.htm. Accessed 9 Nov 2011
12. L Canis T Seager I Linkov 2010 Selecting nanomanufacturing technology using integrated risk, life-cycle assessment and decision-analytical framework Environ Sci Technol 44 8704 8711 10.1021/es102117k 1:CAS:528:DC%2BC3cXhtlansL7N
13. FM Christensen 2010 Reflections from an OECD workshop on environmental benefits of nanotechnology Int J Life Cycle Assess 15 137 138 10.1007/s11367-009-0145-x
14. F Christensen S Olsen 2004 The potential role of life-cycle assessment in regulation of chemicals in the European Union Int J Life Cycle Assess 9 327 332 10.1007/BF02979422 1:CAS:528:DC%2BD2cXptFGrtrc%3D
15. FM Christensen HJ Johnston V Stone RJ Aitken S Hankin S Peters K Aschberger 2010 Nano-silver-feasibility and challenges for human health risk assessment based on open literature Nanotoxicol 4 284 295 10.3109/ 17435391003690549 1:CAS:528:DC%2BC3cXhtl2jsLvI
16. 2-feasibility and challenges for human health risk assessment based on open literature Nanotoxicol 5 110 124 10.3109/17435390.2010.504899 1:CAS:528:DC%2BC3MXhtFCqur3N
17. K Clark RH White EK Wilbergeld 2011 Predictive models for nanotoxicology: current challenges and future opportunities Regul Toxicol Pharm 59 361 363 10.1016/j.yrtph.2011.02.002 1:CAS:528:DC%2BC3MXjs1Wit7w%3D
18. SJ Cowell R Fairman RE Lofstedt 2002 Use of risk assessment and life-cycle assessment in decision making: a common policy research agenda Risk Anal 22 879 894 10.1111/1539-6924.00258
19. JM Davis 2007 How to assess the risks of nanotechnology: learning from past experience J Nanosci Nanotechnol 7 402 409 10.1166/jnn.2007.152 1:CAS:528:DC%2BD2sXjvVyht7c%3D
20. Department for Environment, Food and Rural Affairs (DEFRA) (2007) Characterising the potential risks posed by engineered nanoparticles: second UK Government research report. UK Department for Environment, Food and Rural Affairs, London. http://files.nanobio-raise.org/Downloads/nanoriskrep07.pdf. Accessed 9 Nov 2011
21. Environmental Defense (ED) and Dupont (2007a) Nano risk framework. Environmental Defense-Dupont Nano Partnership, Washington, DC. http://apps.edf.org/documents/6496-nano%20risk%20framework.pdf. Accessed 9 Nov 2011
22. Environmental Defense (ED) and Dupont (2007b) Nanomaterial risk assessment worksheet: DuPont™ light stabilizer for use as a polymer additive. Environmental Defense-Dupont Nano Partnership, Washington, DC. http://epa.gov/oppt/nano/dupont1.pdf. Accessed 9 Nov 2011
23. Environmental Defense (ED) and Dupont (2007c) Nanomaterial risk assessment worksheet: incorporation of single and multi walled carbon nano tubes (CNTs) into polymer nanocomposites by melt processing. Environmental Defense-Dupont Nano Partnership, Washington, DC. http://www.nanoriskframework. com/files/2011/11/6914-CNTs-Worksheet.pdf. Accessed 9 Nov 2011
24. Environmental Defense (ED) and Dupont (2007d) Nanomaterial risk Assessment worksheet: zero valent nano sized iron nanoparticles (nZVI) for environmental remediation. Environmental Defense-Dupont Nano Partnership, Washington, DC. http://www2.dupont.com/Media-Center/en-US/assets/downloads/pdf/ NRAW-nZVI.pdf. Accessed 9 Nov 2011
25. European Chemicals Agency (ECHA) (2010) Guidance on information requirements and chemical safety assessment. http://guidance.echa.europa.eu/ docs/guidance-document/information-requirements-en.htm?time=1289468158. Accessed 9 Nov 2011
26. European Commission (EC) (2003) Technical guidance document in support of commission directive 93/67/EEC on risk assessment for new notified substances and commission regulation (EC) 1488/94 on risk assessment for existing substances. European Commission, Brussels. http://ihcp.jrc.ec.europa.eu/our- activities/public-health/risk-assessment-of-Biocides/doc/tgd/tgdpart2-2ed.pdf. Accessed 9 Nov 2011
27. European Commission (EC) (2004) Towards a European strategy for nanotechnology. http://cordis.europa.eu/nanotechnology/actionplan.htm. Accessed 9 Nov 2011
28. European Commission (EC) (2010) International reference life-cycle data system (ILCD). In: Handbook of general guide for life-cycle assessment. Joint Research Centre, Institute for Environment and Sustainability, Luxembourg. http://lct.jrc.ec.europa.eu/pdf-directory/ILCD-Handbook-General-guide-for-LCA- DETAIL-online-12March2010.pdf. Accessed 9 Nov 2011
29. European Commission (EC) (2011a) Commission recommendation of 18 October 2011 on the definition of nanomaterial. Off J Eur Union L 275:38-40. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2011:275:0038:0040: EN:PDF. Accessed 9 Nov 2011
30. European Commission (EC) (2011b) Europe-wide life-cycle thinking essential for sustainable nanotechnology applications. http://ec.europa.eu/ environment/etap/inaction/policynews/702-en.html. Accessed 9 Nov 2011
31. European Communities (2007) Corrigendum to regulation (EC) No. 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the registration, evaluation, authorisation and restriction of chemicals (REACH), establishing a European Chemicals Agency, amending directive 1999/45/EC and repealing council regulation (EEC) No. 793/93 and commission regulation (EC) No. 1488/94 as well as Council Directive 76/769/EEC and commission directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC (OJ L 396, 30.12.2006). Off J Eur Union L 136:3-280. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ: L:2007:136:0003:0280:en:PDF. Accessed 9 Nov 2011
32. European Technology Platform for Advanced Engineering Materials and Technologies (EUMAT) (2011). Specialist brainstorming and coordination meeting on "life-cycle assessment (LCA) and risk analysis in nanomaterials-related NMP projects", Brussels. http://eumat.eu/Events/default.aspx?EventID=2912. Accessed 9 Nov 2011
33. JS Evans P Hofstetter TE McKone JK Hammitt R Lofstedt 2002 Introduction to special issue on life-cycle assessment and risk analysis Risk Anal 22 819 820
34. Flemström K, Carlson R, Erixon M (2004) Relationships between life-cycle assessment and risk assessment-potentials and obstacles. Report 5379, industrial environmental informatics (IMI). Chalmers University of Technology. http://www.naturvardsverket.se/Documents/publikationer/620-5379-5.pdf. Accessed 9 Nov 2011
35. S Gavankar S Suh AF Keller 2012 Life-cycle assessment at nanoscale: review and recommendations Int J Life Cycle Assess 17 295 303 10.1007/s11367-011-0368-5
36. K Grieger SF Hansen A Baun 2009 The known unknowns of nanomaterials: describing and characterizing uncertainty within environmental, health and safety risks Nanotoxicol 3 1 12 10.1080/17435390902944069
37. Grieger K, Linkov I, Hansen SF, Baun A (2011) Environmental risk analysis for nanomaterials: review and evaluation of frameworks. Nanotoxicology. doi: 10.3109/17435390.2011.569095
38. FG Grubb RB Bakshi 2011 Life-cycle of titanium dioxide nanoparticle production J Ind Ecol 15 81 95 10.1111/j.1530-9290.2010.00292.x 1:CAS:528:DC%2BC3MXksFSlsbw%3D
39. 2). NEDO project research and development of nanoparticle characterization methods, Report No. P06041. http://goodnanoguide.org/tiki-download-wiki-attachment.php? attId=32. Accessed 9 Nov 2011
40. Hankin SM, Peters SAK, Poland CA et al. (2011) Specific advice on fulfilling information requirements for nanomaterials under REACH (RIP-No. 2). Final project report, RNC/RIP-oN2/FPR/1/FINAL. http://ec.europa.eu/environment/ chemicals/nanotech/pdf/report-ripon2.pdf. Accessed 9 Nov 2011
41. MZ Hauschild 2005 Assessing environmental impacts in a life-cycle perspective Environ Sci Technol 39 81A 88A 10.1021/es053190s 1:CAS:528:DC%2BD2MXht1Okur8%3D
42. CO Hendren X Mesnard J Dröge MR Wiesner 2011 Estimating production data for five engineered nanomaterials as a basis for exposure assessment Environ Sci Technol 45 2562 2569 10.1021/es103300g 1:CAS:528: DC%2BC3MXivFyju7Y%3D
43. R Hischier T Walser 2012 Life-cycle assessment of engineered nanomaterials: state of the art and strategies to overcome existing gaps Sci Total Environ 425 271 282 10.1016/j.scitotenv.2012.03.001 1:CAS:528: DC%2BC38XlvFejtLs%3D
44. Höck J, Hofmann H, Krug H, Lorenz C, Limbach L, Nowack B, Riediker M, Schischke K, Som C, Stark W et al. (2008) Guidelines on the precautionary matrix for synthetic nanomaterials, Version 1. Swiss Federal Office for Public Health and Federal Office for the Environment, Berne. http://www.temas.ch/ wwwtemas/temas-homepage.nsf/vwRes/Spiegel-051/FILE/Raster-021208-EN.pdf. Accessed 9 Nov 2011
45. Höck J, Epprecht T, Hofmann H, Höhner K, Krug H, Lorenz C, Limbach L, Gehr P, Nowack B, Riediker M et al. (2010) Guidelines on the precautionary matrix for synthetic nanomaterials, Version 2.1. Swiss Federal Office for Public Health and Federal Office for the Environment, Berne. http://www.temas.ch/wwwtemas/temas-homepage.nsf/vwRes/NanoSR26/FILE/ Wegleitung-e.pdf. Accessed 9 Nov 2011
46. International Organization for Standardization (ISO) (2006a) Environmental management-life-cycle assessment-requirements and guidelines (ISO 14044:2006). http://www.iso.org/iso/catalogue-detail?csnumber=38498. Accessed 9 Nov 2011
47. International Organization for Standardization (ISO) (2006b) Environmental management-life-cycle assessment-principles and framework (ISO 14040:2006). http://www.iso.org/iso/catalogue-detail?csnumber=37456. Accessed 9 Nov 2011
48. International Organization for Standardization (ISO) (2008) Spécification technique international nanotechnologies-terminology and definitions for nano-objects-nanoparticle, nanofibre and nanoplate. http://www.iso.org/iso/iso-catalogue/catalogue-tc/catalogue-detail.htm?csnumber= 44278. Accessed 17 June 2012
49. International Organization for Standardization (ISO) (2011) Nanotechnologies-nanomaterial risk evaluation (ISO/TR 13121). http://www.iso.org/iso/catalogue-detail.htm?csnumber=52976. Accessed 9 Nov 2011
50. International Risk Governance Council (IRGC) (2005) Risk governance: towards an integrative approach. IRGC, Geneva. http://www.irgc.org/IMG/pdf/IRGC- WP-No-1-Risk-Governance-reprinted-version-.pdf. Accessed 9 Nov 2011
51. International Risk Governance Council (IRGC) (2007) Nanotechnology risk governance: recommendations for a global, coordinated approach to the governance of potential risks. IRGC, Geneva. http://www.irgc.org/IMG/pdf/PB-nanoFINAL2-2-. pdf. Accessed 9 Nov 2011
52. International Risk Governance Council (IRGC) (2009) Appropriate risk governance strategies for nanotechnology applications in food and cosmetics. IRGC, Geneva. http://www.irgc.org/IMG/pdf/irgc-nanotechnologies-food-and- cosmetics-policy-brief.pdf. Accessed 9 Nov 2011
53. V Khanna BR Bakshi LJ Lee 2008 Carbon nanofiber production J Ind Ecol 12 394 410 10.1111/j.1530-9290.2008.00052.x 1:CAS:528:DC%2BD1cXht1yisrvM
54. Khanna V, Bakshi BR, Lee LJ (2008b) Assessing life-cycle environmental implications of polymer nanocomposites. IEEE Int Symp Electron Environ 1-6
55. Klöpffer W, Curran MA, Frankl P et al. (2007) Nanotechnology and life-cycle assessment: a systems approach to nanotechnology and the environment. Woodrow Wilson International Center for Scholars, Project on Emerging Nanotechnologies, Washington, DC. http://www.nanotechproject.org/file-download/ files/NanoLCA-3.07.pdf. Accessed 9 Nov 2011
56. Kobayashi N, Ogura I, Gamo M, Kishimoto A, Nakanishi J (2009) Risk assessment of manufactured nanomaterials-carbon nanotbues (CNTs). Report No. P06041, NEDO project research and development of nanoparticle characterization methods. http://goodnanoguide.org/tiki-download-wiki-attachment.php?attId=31. Accessed on 9 Nov 2011
57. N Krishnan S Boyd A Somani S Raoux D Clark D Dornfeld 2008 A hybrid life-cycle inventory of nano-scale semiconductor manufacturing Environ Sci Technol 42 3069 3075 10.1021/es071174k 1:CAS:528:DC%2BD1cXjsVGnsb8%3D
58. B Kuczenski R Geyer B Boughton 2010 Tracking toxicants: towards a life-cycle aware risk assessment Environ Sci Technol 45 45 50 10.1021/es101467z
59. LEITAT (2011) Safety issues of nanomaterials along their life-cycle. LEITAT Technological Center, Symposium 4-5 May 2011, Barcelona. http://www.leitat.org/nanoLCA/index.htm. Accessed 9 Nov 2011
60. SR Lim CW Lam JM Schoenung 2011 Priority screening of toxic chemicals and industry sectors in the US toxics release inventory: a comparison of the life-cycle impact-based and risk-based assessment tools developed by US EPA J Environ Manag 92 2235 2240 10.1016/j.jenvman.2011.04.008 1:CAS:528: DC%2BC3MXntF2nsr4%3D
61. I Linkov T Seager 2011 Coupling multi-criteria decision analysis, life-cycle assessment, and risk assessment for emerging threats Environ Sci Technol 45 5068 5074 10.1021/es100959q 1:CAS:528:DC%2BC3MXlt1ShtLY%3D
62. I Linkov FK Satterstrom J Steevens E Ferguson RC Pleus 2007 Multi-criteria decision analysis and environmental risk assessment for nanomaterials J Nanoparticle Res 9 543 554 10.1007/s11051-007-9211-0
63. Linkov I, Bates ME, Canis LJ, Seager TP, Keisler JM (2011) A decision-directed approach for prioritizing research into the impact of nanomaterials on the environment and human health. Nat Nanotechnol 6:784-787
64. Merugula AL, Khanna V, Bakshi RB (2010) Comparative life-cycle assessment: reinforcing wind turbine blades with carbon nanofibers. In: Proceedings of the 2010 IEEE international symposium on sustainable systems and technology, p 5507724
65. ED Meyer MA Curran MA Gonzalez 2010 An examination of silver nanoparticles in socks using screening-level life-cycle assessment J Nanoparticle Res 13 147 156 10.1007/s11051-010-0013-4
66. A Moign A Vardelle NJ Themelis JG Legoux 2010 Life-cycle assessment of using powder and liquid precursors in plasma spraying: the case of yttria-stabilized zirconia Surf Coat Technol 205 668 673 10.1016/j.surfcoat. 2010.07.015 1:CAS:528:DC%2BC3cXhtFGjsbnI
67. Nanopolytox (2011) Toxicological impact of nanomaterials derived from processing, weathering and recycling from polymer nanocomposites used in various industrial applications. European Union F7 project. http://www.nanopolytox.eu/. Accessed 9 Nov 2011
68. Nanovalid (2010) NANOVALID-Seventh Framework Programme (FP7). http://www.venetonanotech.it/it/news-eventi/news-dal-distretto/ nanovalid-seventh-framework-programme-fp7,3,9959. Accessed 9 Nov 2011
69. National Science Foundation (NSF) (2007) NER: identifying and regulating environmental impacts of nanomaterials. www.nsf.gov/awardsearch/showAward.do? AwardNumber=0508347&version=noscript. Accessed 9 Nov 2011
70. NEPHH (2011) Nanomaterials related environmental pollution and health hazards throughout their life-cycle. http://www.nephh-fp7.eu/. Accessed 9 Nov 2011
71. Y Nishioka JI Levy GA Norris A Wilson P Hofstetter JD Spengler 2002 Integrating risk assessment and life-cycle assessment: a case study of insulation Risk Anal 5 1003 1017 10.1111/1539-6924.00266
72. NJ O'Brien EJ Cummins 2011 A risk assessment framework for assessing metallic nanomaterials of environmental concern: aquatic exposure and behaviour Risk Anal 5 706 726 10.1111/j.1539-6924.2010.01540.x
73. SI Olsen FM Christensen M Hauschild F Pedersen HF Larsen J Tørsløv 2001 Life-cycle impact assessment and risk assessment of chemicals-a methodological comparison Environ Impact Assess Rev 21 385 404 10.1016/S0195-9255(01)00075-0
74. Organisation for Economic Co-operation and Development (OECD) (2009) Preliminary review of OECD test guidelines for their applicability to manufactured nanomaterials. Report No. ENV/JM/MONO(2009)21, Environment Directorate, Joint Meeting of the Chemicals Committee and the Working Party on chemicals, pesticides and biotechnology, Paris. http://www.oecd.org/document/53/ 0,3746,en-2649-37015404-37760309-1-1-1-1,00&&en-USS-01DBC.html. Accessed 9 Nov 2011
75. Organisation for Economic Co-operation and Development (OECD) (2010) Current developments/activities on the safety of manufactured nanomaterials: Tour de Table at the 6th meeting of the working party on manufactured nanomaterials. Report No. ENV/JM/MONO(2010)4, Paris. http://www.oecd.org/ document/53/0,3746,en-2649-37015404-37760309-1-1-1-1,00&&en-USS-01DBC. html. Accessed 9 Nov 2011
76. Organisation for Economic Co-operation and Development (OECD) (2011) OECD database on research into the safety of manufactured nanomaterials. http://webnet.oecd.org/NanoMaterials/Pagelet/Front/Default.aspx. Accessed 9 Nov 2011
77. JW Owens 1997 Life-cycle assessment in relation to risk assessment: an evolving perspective Risk Anal 17 359 365 10.1111/j.1539-6924.1997.tb00874.x
78. R Pant G Van Hoof D Schowanek TCJ Feijtel A de Koning M Hauschild DW Pennington SI Olsen R Rosenbaum 2004 Comparison between three different LCIA methods for aquatic ecotoxicity and a product environmental risk assessment Int J Life Cycle Assess 9 295 306 10.1007/BF02979419 1:CAS:528:DC%2BD2cXptFGrtrg%3D
79. Prosuite (2011) Development and application of standardized methodology for the prospective sustainability assessment of technologies. European Union FP7. http://www.prosuite.org. Accessed 9 Nov 2011
80. U Pyell 2010 Characterization of nanoparticles by capillary electromigration separation techniques Electrophoresis 31 814 831 10.1002/elps.200900555 1:CAS:528:DC%2BC3cXis1ems7o%3D
81. Renn O (2008) Risk governance: coping with uncertainty in a complex world, Earthscan, London
82. CO Robichaud D Tanzil U Weilenmann MR Wiesner 2005 Relative risk analysis of several manufactured nanomaterials: an insurance industry context Environ Sci Technol 39 8985 8994 10.1021/es0506509 1:CAS:528:DC%2BD2MXhtVGqs7nL
83. Rocks S, Pollard S, Dorey R, Levy L, Harrison P, Handy R (2008) Comparison of risk assessment approaches for manufactured nanomaterials. Defra project (CB403). Cranfield University. http://www.cranfield.ac.uk/health/ researchareas/environmenthealth/ieh/page26480.html. Accessed 9 Nov 2011
84. RK Rosenbaum TM Bachmann LS Gold, et al. 2008 USEtox, the UNEP-SETAC toxicity model: recommended characterisation factors for human toxicity and freshwater ecotoxicity in life-cycle impact assessment Int J Life Cycle Assess 13 532 546 10.1007/s11367-008-0038-4 1:CAS:528:DC%2BD1MXmslKl
85. Royal Society and Royal Academy of Engineering (2004) Nanoscience and nanotechnologies: opportunities and uncertainties. The UK Royal Society, London. http://www.nanotec.org.uk/finalReport.htm. Accessed 9 Nov 2011
86. AJ Russel 2007 Human and ecological risk assessment and life-cycle assessment: intersections, collisions, and future directions Hum Ecol Risk Asess 12 427 430 10.1080/10807030600561642
87. Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) (2009) Risk assessment of products of nanotechnologies. European Commission Health and Consumer Protection Directorate-General, Directorate C-public health and risk assessment, C7-risk assessment, Brussels. http://ec.europa.eu/health/ph-risk/committees/04-scenihr/docs/scenihr-o-023.pdf. Accessed 9 Nov 2011
88. Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) (2010) Scientific basis for the definition of the term "nanomaterial." European Commission Health and Consumer Protection Directorate-General, Directorate C-public health and risk assessment, C7-risk assessment, Brussels. http://ec.europa.eu/health/scientific-committees/emerging/ docs/scenihr-o-032.pdf. Accessed 9 Nov 2011
89. TP Seager I Linkov 2008 Coupling multicriteria decision analysis and life-cycle assessment for nanomaterials J Ind Ecol 12 282 285 10.1111/j.1530-9290.2008.00048.x
90. Seager TP, Linkov I (2009) Uncertainty in life-cycle assessment of nanomaterials: multi-criteria decision analysis framework for single wall carbon nanotubes in power applications. In: Steevens J (ed) Linkov I. Nanomaterials: risks and benefits, Springer, pp 423-436
91. H Sengül LT Theis 2011 An environmental impact assessment of quantum dot photovoltaics (QDPV) from raw material acquisition through use J Clean Prod 19 21 31 10.1016/j.jclepro.2010.08.010
92. JA Shatkin 2008 Informing environmental decision making by combining life-cycle assessment and risk analysis J Ind Ecol 12 278 281 10.1111/j.1530-9290.2008.00031.x
93. Shatkin JA (2008b) Nanotechnology: health and environmental risks. CRC Press, Boca Raton. http://www.uotechnology.edu.iq/NTRC/PDF/nano/ Nanotechnology%20Health%20And%20Enviroment.pdf. Accessed 9 Nov 2011
94. Shatkin JA (2009a) Investigating the life-cycle risks of a nanomaterial in a coating using nano LCRA. Society for risk analysis annual meeting. Symposium M4-I, Baltimore
95. Shatkin JA (2009b) Risk analysis for nanotechnology: state of the science and implications. US Department of Agriculture, Washington, DC. http://www.usda.gov/oce/risk-assessment/risk-forums/Shatkin100709.pdf. Accessed 9 Nov 2011
96. Shinohara N, Gamo M, Nakanishi J (2009) Risk assessment of manufactured nanomaterials-Fullerene (C60). Report No. P06041, NEDO project research and development of nanoparticle characterization methods. http://goodnanoguide.org/ tiki-download-wiki-attachment.php?attId=29. Accessed 9 Nov 2011
97. ML Socolof JR Geibig 2006 Evaluating human and ecological impacts of a product life-cycle: the complementary roles of life-cycle assessment and risk assessment Hum Ecol Risk Assess 12 510 527 10.1080/10807030600582796 1:CAS:528:DC%2BD28Xntl2nsb0%3D
98. C Som M Berges Q Chaudhry M Dusinska T Fernandes S Olsen B Nowack 2010 The importance of life-cycle concepts for the development of safe nanoproducts Toxicol 269 160 169 10.1016/j.tox.2009.12.012 1:CAS:528:DC%2BC3cXjslSitb8%3D
99. C Som P Wick H Krug B Nowack 2011 Environmental and health effects of nanomaterials in nanotextiles and facade coatings Environ Int 37 1131 1142 10.1016/j.envint.2011.02.013 1:CAS:528:DC%2BC3MXnsVWnu7w%3D
100. Stone V, Aitken R, Aschberger K, Baun A, Christensen FM, Fernandes TF, Hansen SF, Hartmann NB, Hutchison G, Johnston H et al. (2010) Engineered nanoparticles: review of health and environmental safety (ENRHES). Final report, ENRHES FP 7 project. http://ihcp.jrc.ec.europa.eu/whats-new/enhres-final- report. Accessed 9 Nov 2011
101. L Sweet B Strohm 2006 Nanotechnology-life-cycle risk management Hum Ecol Risk Assess 12 528 551 10.1080/10807030600561691 1:CAS:528:DC%2BD28Xntl2nsbo%3D
102. Swiss Federal Office for the Environment (FOEN) (2010) Workplace safety is first priority. http://www.bafu.admin.ch/dokumentation/umwelt/10649/10660/ index.html?lang=en. Accessed 4 Nov 2010
103. Swiss Federal Office of Public Health (2010) Application of precautionary matrix on life-cycle of anti-fingerprint product. 2nd NanoImpactNet conference, Lausanne
104. T Tervonen I Linkov JR Figueira J Steevens M Chappell M Merad 2009 Risk-based classification system of nanomaterials J Nanoparticle Res 11 757 766 10.1007/s11051-008-9546-1 1:CAS:528:DC%2BD1MXktVGku7g%3D
105. TÜV SÜD (2008) Certification standard CENARIOS®.TÜV SÜD Industrie Service GmbH, Munich, DE. http://www.tuev-sued.de/uploads/ images/1219824286015340810363/CENARIOS-Zertifiziergrundlage-e.pdf. Accessed 9 Nov 2011
106. US Army Environmental Policy Institute (2009) Army Environmental Policy Institute (AEPI) report: managing the life-cycle risks of nanomaterials. Army Environmental Policy Institute, Arlington. http://www.aepi.army.mil/docs/ whatsnew/Managing-the-Life-Cycle-Risks-of-Nanomaterials-Final-July-2009.pdf. Accessed 9 Nov 2011
107. US Environmental Protection Agency (US EPA) (2008) Draft nanomaterial research strategy. Report No. EPA/600/S-08/002, Office of Research and Development. http://epa.gov/ncer/nano/publications/nano
108. US Environmental Protection Agency (US EPA) (2009) External review draft nanomaterial case studies: nanoscale titanium dioxide in water treatment and in topical sunscreen. Report No. EPA/600/R-09/057, National Center for Environmental Assessment, Office of Research and Development, Research Triangle Park. http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=210206. Accessed 9 Nov 2011
109. US Environmental Protection Agency (US EPA) (2010a) Nanomaterial case study: Nanoscale silver in disinfectant spray (external review draft). Report No. EPA/600/R-10/081, Washington, DC. http://cfpub.epa.gov/ncea/cfm/ recordisplay.cfm?deid=226723. Accessed 9 Nov 2011
110. US Environmental Protection Agency (US EPA) (2010b) Nanomaterial case studies workshop: Developing a comprehensive environmental assessment research strategy for nanoscale titanium dioxide. Report No. EPA/600/R-10/042, National Center for Environmental Assessment-RTP Division Office of Research and Development, Research Triangle Park. ofmpub.epa.gov/eims/eimscomm.getfile?p- download-id=505179. Accessed 9 Nov 2011
111. LJ Valverde I Linkov 2011 Nanotechnology: risk assessment and risk management perspective Nanotechnol Law Bus 8 25 47
112. A Wardak ME Gorman N Swami S Deshpande 2008 Identification of risks in the life-cycle of nanotechnology-based products J Ind Ecol 12 435 448 10.1111/j.1530-9290.2008.00029.x 1:CAS:528:DC%2BD1cXht1yisrvO
113. DB Warheit 2008 How meaningful are the results of nanotoxicity studies in the absence of adequate material characterization? Toxicol Sci 101 183 185 10.1093/toxsci/kfm279 1:CAS:528:DC%2BD1cXmsV2ruw%3D%3D
114. Wrisberg N, de Haes U (2002) Analytical tools for environmental design and management in a systems perspective. Kluwer Academic Publishers, The Netherlands