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Volumn 39, Issue 1-2, 2012, Pages 83-92

Aberrant localization of fusion receptors involved in regulated exocytosis in salivary glands of Sjögren's syndrome patients is linked to ectopic mucin secretion

Author keywords

Ectopic mucin secretion; Mislocalization of fusion complexes; Regulated secretion; Salivary glands; Sj gren's syndrome; SNARE proteins

Indexed keywords

HYBRID PROTEIN; MESSENGER RNA; MUCIN; SNARE PROTEIN; SYNAPTOBREVIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; SYNTAXIN; SYNTAXIN 3; SYNTAXIN 4; UNCLASSIFIED DRUG; VAMP 8 PROTEIN;

EID: 84862502800     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2012.01.011     Document Type: Article
Times cited : (44)

References (36)
  • 1
    • 77956281536 scopus 로고    scopus 로고
    • Pathogenetic mechanisms in the initiation and perpetuation of Sjogren's syndrome
    • Voulgarelis M., Tzioufas A.G. Pathogenetic mechanisms in the initiation and perpetuation of Sjogren's syndrome. Nat Rev Rheumatol 2010, 6:529-537.
    • (2010) Nat Rev Rheumatol , vol.6 , pp. 529-537
    • Voulgarelis, M.1    Tzioufas, A.G.2
  • 4
    • 0033621786 scopus 로고    scopus 로고
    • Innervation pattern and Ca2+ signalling in labial salivary glands of healthy individuals and patients with primary Sjogren's syndrome (pSS)
    • Pedersen A.M., Dissing S., Fahrenkrug J., Hannibal J., Reibel J., Nauntofte B. Innervation pattern and Ca2+ signalling in labial salivary glands of healthy individuals and patients with primary Sjogren's syndrome (pSS). J Oral Pathol Med 2000, 29:97-109.
    • (2000) J Oral Pathol Med , vol.29 , pp. 97-109
    • Pedersen, A.M.1    Dissing, S.2    Fahrenkrug, J.3    Hannibal, J.4    Reibel, J.5    Nauntofte, B.6
  • 5
    • 0035068208 scopus 로고    scopus 로고
    • Impaired neurotransmitter release from lacrimal and salivary gland nerves of a murine model of Sjogren's syndrome
    • Zoukhri D., Kublin C.L. Impaired neurotransmitter release from lacrimal and salivary gland nerves of a murine model of Sjogren's syndrome. Invest Ophthalmol Vis Sci 2001, 42:925-932.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 925-932
    • Zoukhri, D.1    Kublin, C.L.2
  • 6
    • 33646343709 scopus 로고    scopus 로고
    • Antimuscarinic antibodies in primary Sjogren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cells
    • Dawson L.J., Stanbury J., Venn N., Hasdimir B., Rogers S.N., Smith P.M. Antimuscarinic antibodies in primary Sjogren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cells. Arthritis Rheum 2006, 54:1165-1173.
    • (2006) Arthritis Rheum , vol.54 , pp. 1165-1173
    • Dawson, L.J.1    Stanbury, J.2    Venn, N.3    Hasdimir, B.4    Rogers, S.N.5    Smith, P.M.6
  • 7
    • 67650088392 scopus 로고    scopus 로고
    • A role for nitric oxide-mediated glandular hypofunction in a non-apoptotic model for Sjogren's syndrome
    • Caulfield V.L., Balmer C., Dawson L.J., Smith P.M. A role for nitric oxide-mediated glandular hypofunction in a non-apoptotic model for Sjogren's syndrome. Rheumatology (Oxford) 2009, 48:727-733.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 727-733
    • Caulfield, V.L.1    Balmer, C.2    Dawson, L.J.3    Smith, P.M.4
  • 8
    • 33745596422 scopus 로고    scopus 로고
    • Sjogrens syndrome-the non-apoptotic model of glandular hypofunction
    • Dawson L.J., Fox P.C., Smith P.M. Sjogrens syndrome-the non-apoptotic model of glandular hypofunction. Rheumatology (Oxford) 2006, 45:792-798.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 792-798
    • Dawson, L.J.1    Fox, P.C.2    Smith, P.M.3
  • 9
    • 34547804674 scopus 로고    scopus 로고
    • Modified aquaporin 5 expression and distribution in submandibular glands from NOD mice displaying autoimmune exocrinopathy
    • Soyfoo M.S., De Vriese C., Debaix H., Martin-Martinez M.D., Mathieu C., Devuyst O., et al. Modified aquaporin 5 expression and distribution in submandibular glands from NOD mice displaying autoimmune exocrinopathy. Arthritis Rheum 2007, 56:2566-2574.
    • (2007) Arthritis Rheum , vol.56 , pp. 2566-2574
    • Soyfoo, M.S.1    De Vriese, C.2    Debaix, H.3    Martin-Martinez, M.D.4    Mathieu, C.5    Devuyst, O.6
  • 10
    • 80053521118 scopus 로고    scopus 로고
    • Changes in Rab3D expression and distribution in the acini of Sjogren's syndrome patients are associated with loss of cell polarity and secretory dysfunction
    • Bahamondes V., Albornoz A., Aguilera S., Alliende C., Molina C., Castro I., et al. Changes in Rab3D expression and distribution in the acini of Sjogren's syndrome patients are associated with loss of cell polarity and secretory dysfunction. Arthritis Rheum 2011, 63:3126-3135.
    • (2011) Arthritis Rheum , vol.63 , pp. 3126-3135
    • Bahamondes, V.1    Albornoz, A.2    Aguilera, S.3    Alliende, C.4    Molina, C.5    Castro, I.6
  • 11
    • 0029620763 scopus 로고
    • Salivary mucins: protective functions in relation to their diversity
    • Amerongen A.V., Bolscher J.G., Veerman E.C. Salivary mucins: protective functions in relation to their diversity. Glycobiology 1995, 5:733-740.
    • (1995) Glycobiology , vol.5 , pp. 733-740
    • Amerongen, A.V.1    Bolscher, J.G.2    Veerman, E.C.3
  • 12
    • 53149100489 scopus 로고    scopus 로고
    • Reduced sulfation of muc5b is linked to xerostomia in patients with Sjogren syndrome
    • Alliende C., Kwon Y.J., Brito M., Molina C., Aguilera S., Perez P., et al. Reduced sulfation of muc5b is linked to xerostomia in patients with Sjogren syndrome. Ann Rheum Dis 2008, 67:1480-1487.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1480-1487
    • Alliende, C.1    Kwon, Y.J.2    Brito, M.3    Molina, C.4    Aguilera, S.5    Perez, P.6
  • 13
    • 77951711146 scopus 로고    scopus 로고
    • Disruption of tight junction structure in salivary glands from Sjogren's syndrome patients is linked to proinflammatory cytokine exposure
    • Ewert P., Aguilera S., Alliende C., Kwon Y.J., Albornoz A., Molina C., et al. Disruption of tight junction structure in salivary glands from Sjogren's syndrome patients is linked to proinflammatory cytokine exposure. Arthritis Rheum 2010, 62:1280-1289.
    • (2010) Arthritis Rheum , vol.62 , pp. 1280-1289
    • Ewert, P.1    Aguilera, S.2    Alliende, C.3    Kwon, Y.J.4    Albornoz, A.5    Molina, C.6
  • 14
    • 39349092547 scopus 로고    scopus 로고
    • Core proteins of the secretory machinery
    • Lang T., Jahn R. Core proteins of the secretory machinery. Handb Exp Pharmacol 2008, 107-127.
    • (2008) Handb Exp Pharmacol , pp. 107-127
    • Lang, T.1    Jahn, R.2
  • 15
    • 78149306025 scopus 로고    scopus 로고
    • Multisubunit tethering complexes and their role in membrane fusion
    • Brocker C., Engelbrecht-Vandre S., Ungermann C. Multisubunit tethering complexes and their role in membrane fusion. Curr Biol 2010, 20:R943-R952.
    • (2010) Curr Biol , vol.20
    • Brocker, C.1    Engelbrecht-Vandre, S.2    Ungermann, C.3
  • 16
    • 0036092482 scopus 로고    scopus 로고
    • Classification criteria for Sjogren's syndrome: a revised version of the European criteria proposed by the American-European consensus group
    • Vitali C., Bombardieri S., Jonsson R., Moutsopoulos H.M., Alexander E.L., Carsons S.E., et al. Classification criteria for Sjogren's syndrome: a revised version of the European criteria proposed by the American-European consensus group. Ann Rheum Dis 2002, 61:554-558.
    • (2002) Ann Rheum Dis , vol.61 , pp. 554-558
    • Vitali, C.1    Bombardieri, S.2    Jonsson, R.3    Moutsopoulos, H.M.4    Alexander, E.L.5    Carsons, S.E.6
  • 17
    • 79953715158 scopus 로고    scopus 로고
    • Alterations in type I hemidesmosome components suggestive of epigenetic control in the salivary glands of patients with Sjogren's syndrome
    • Gonzalez S., Aguilera S., Alliende C., Urzua U., Quest A.F., Herrera L., et al. Alterations in type I hemidesmosome components suggestive of epigenetic control in the salivary glands of patients with Sjogren's syndrome. Arthritis Rheum 2011, 63:1106-1115.
    • (2011) Arthritis Rheum , vol.63 , pp. 1106-1115
    • Gonzalez, S.1    Aguilera, S.2    Alliende, C.3    Urzua, U.4    Quest, A.F.5    Herrera, L.6
  • 18
    • 33750945342 scopus 로고    scopus 로고
    • Involvement of specific laminins and nidogens in the active remodeling of the basal lamina of labial salivary glands from patients with Sjogren's syndrome
    • Kwon Y.J., Perez P., Aguilera S., Molina C., Leyton L., Alliende C., et al. Involvement of specific laminins and nidogens in the active remodeling of the basal lamina of labial salivary glands from patients with Sjogren's syndrome. Arthritis Rheum 2006, 54:3465-3475.
    • (2006) Arthritis Rheum , vol.54 , pp. 3465-3475
    • Kwon, Y.J.1    Perez, P.2    Aguilera, S.3    Molina, C.4    Leyton, L.5    Alliende, C.6
  • 19
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 20
    • 55549123198 scopus 로고    scopus 로고
    • The structural and functional implications of linked SNARE motifs in SNAP25
    • Wang L., Bittner M.A., Axelrod D., Holz R.W. The structural and functional implications of linked SNARE motifs in SNAP25. Mol Biol Cell 2008, 19:3944-3955.
    • (2008) Mol Biol Cell , vol.19 , pp. 3944-3955
    • Wang, L.1    Bittner, M.A.2    Axelrod, D.3    Holz, R.W.4
  • 21
    • 33947168279 scopus 로고    scopus 로고
    • VAMP8/endobrevin as a general vesicular SNARE for regulated exocytosis of the exocrine system
    • Wang C.C., Shi H., Guo K., Ng C.P., Li J., Gan B.Q., et al. VAMP8/endobrevin as a general vesicular SNARE for regulated exocytosis of the exocrine system. Mol Biol Cell 2007, 18:1056-1063.
    • (2007) Mol Biol Cell , vol.18 , pp. 1056-1063
    • Wang, C.C.1    Shi, H.2    Guo, K.3    Ng, C.P.4    Li, J.5    Gan, B.Q.6
  • 22
    • 80051937839 scopus 로고    scopus 로고
    • Vesicle-associated membrane protein 8 (VAMP8) is a SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) selectively required for sequential granule-to-granule fusion
    • Behrendorff N., Dolai S., Hong W., Gaisano H.Y., Thorn P. Vesicle-associated membrane protein 8 (VAMP8) is a SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) selectively required for sequential granule-to-granule fusion. J Biol Chem 2011, 286:29627-29634.
    • (2011) J Biol Chem , vol.286 , pp. 29627-29634
    • Behrendorff, N.1    Dolai, S.2    Hong, W.3    Gaisano, H.Y.4    Thorn, P.5
  • 23
    • 34248218249 scopus 로고    scopus 로고
    • Pancreatic acinar cells express vesicle-associated membrane protein 2- and 8-specific populations of zymogen granules with distinct and overlapping roles in secretion
    • Weng N., Thomas D.D., Groblewski G.E. Pancreatic acinar cells express vesicle-associated membrane protein 2- and 8-specific populations of zymogen granules with distinct and overlapping roles in secretion. J Biol Chem 2007, 282:9635-9645.
    • (2007) J Biol Chem , vol.282 , pp. 9635-9645
    • Weng, N.1    Thomas, D.D.2    Groblewski, G.E.3
  • 24
    • 80655149437 scopus 로고    scopus 로고
    • Cholesterol transport from late endosomes to the golgi regulates t-SNARE trafficking, assembly, and function
    • Reverter M., Rentero C., de Muga S.V., Alvarez-Guaita A., Mulay V., Cairns R., et al. Cholesterol transport from late endosomes to the golgi regulates t-SNARE trafficking, assembly, and function. Mol Biol Cell 2011, 22:4108-4123.
    • (2011) Mol Biol Cell , vol.22 , pp. 4108-4123
    • Reverter, M.1    Rentero, C.2    de Muga, S.V.3    Alvarez-Guaita, A.4    Mulay, V.5    Cairns, R.6
  • 26
    • 33846911262 scopus 로고    scopus 로고
    • Mucin granule intraluminal organization
    • Perez-Vilar J. Mucin granule intraluminal organization. Am J Respir Cell Mol Biol 2007, 36:183-190.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 183-190
    • Perez-Vilar, J.1
  • 27
    • 0141564937 scopus 로고    scopus 로고
    • Enhanced degradation of proteins of the basal lamina and stroma by matrix metalloproteinases from the salivary glands of Sjogren's syndrome patients: correlation with reduced structural integrity of acini and ducts
    • Goicovich E., Molina C., Perez P., Aguilera S., Fernandez J., Olea N., et al. Enhanced degradation of proteins of the basal lamina and stroma by matrix metalloproteinases from the salivary glands of Sjogren's syndrome patients: correlation with reduced structural integrity of acini and ducts. Arthritis Rheum 2003, 48:2573-2584.
    • (2003) Arthritis Rheum , vol.48 , pp. 2573-2584
    • Goicovich, E.1    Molina, C.2    Perez, P.3    Aguilera, S.4    Fernandez, J.5    Olea, N.6
  • 28
    • 46749140923 scopus 로고    scopus 로고
    • VAMP8 is the v-SNARE that mediates basolateral exocytosis in a mouse model of alcoholic pancreatitis
    • Cosen-Binker L.I., Binker M.G., Wang C.C., Hong W., Gaisano H.Y. VAMP8 is the v-SNARE that mediates basolateral exocytosis in a mouse model of alcoholic pancreatitis. J Clin Invest 2008, 118:2535-2551.
    • (2008) J Clin Invest , vol.118 , pp. 2535-2551
    • Cosen-Binker, L.I.1    Binker, M.G.2    Wang, C.C.3    Hong, W.4    Gaisano, H.Y.5
  • 29
    • 34250368480 scopus 로고    scopus 로고
    • Alcohol/cholecystokinin-evoked pancreatic acinar basolateral exocytosis is mediated by protein kinase C alpha phosphorylation of Munc18c
    • Cosen-Binker L.I., Lam P.P., Binker M.G., Reeve J., Pandol S., Gaisano H.Y. Alcohol/cholecystokinin-evoked pancreatic acinar basolateral exocytosis is mediated by protein kinase C alpha phosphorylation of Munc18c. J Biol Chem 2007, 282:13047-13058.
    • (2007) J Biol Chem , vol.282 , pp. 13047-13058
    • Cosen-Binker, L.I.1    Lam, P.P.2    Binker, M.G.3    Reeve, J.4    Pandol, S.5    Gaisano, H.Y.6
  • 30
    • 1942539879 scopus 로고    scopus 로고
    • Alcoholic chronic pancreatitis involves displacement of Munc18c from the pancreatic acinar basal membrane surface
    • Gaisano H.Y., Sheu L., Whitcomb D. Alcoholic chronic pancreatitis involves displacement of Munc18c from the pancreatic acinar basal membrane surface. Pancreas 2004, 28:395-400.
    • (2004) Pancreas , vol.28 , pp. 395-400
    • Gaisano, H.Y.1    Sheu, L.2    Whitcomb, D.3
  • 31
    • 4544227227 scopus 로고    scopus 로고
    • A role of VAMP8/endobrevin in regulated exocytosis of pancreatic acinar cells
    • Wang C.C., Ng C.P., Lu L., Atlashkin V., Zhang W., Seet L.F., et al. A role of VAMP8/endobrevin in regulated exocytosis of pancreatic acinar cells. Dev Cell 2004, 7:359-371.
    • (2004) Dev Cell , vol.7 , pp. 359-371
    • Wang, C.C.1    Ng, C.P.2    Lu, L.3    Atlashkin, V.4    Zhang, W.5    Seet, L.F.6
  • 32
    • 0035206785 scopus 로고    scopus 로고
    • Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane
    • Gaisano H.Y., Lutz M.P., Leser J., Sheu L., Lynch G., Tang L., et al. Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane. J Clin Invest 2001, 108:1597-1611.
    • (2001) J Clin Invest , vol.108 , pp. 1597-1611
    • Gaisano, H.Y.1    Lutz, M.P.2    Leser, J.3    Sheu, L.4    Lynch, G.5    Tang, L.6
  • 33
    • 78751613367 scopus 로고    scopus 로고
    • Aberrant localization of ezrin correlates with salivary acini disorganization in Sjogren's Syndrome
    • Perez P., Aguilera S., Olea N., Alliende C., Molina C., Brito M., et al. Aberrant localization of ezrin correlates with salivary acini disorganization in Sjogren's Syndrome. Rheumatology (Oxford) 2010, 49:915-923.
    • (2010) Rheumatology (Oxford) , vol.49 , pp. 915-923
    • Perez, P.1    Aguilera, S.2    Olea, N.3    Alliende, C.4    Molina, C.5    Brito, M.6
  • 34
    • 80053329220 scopus 로고    scopus 로고
    • Divide and polarize: recent advances in the molecular mechanism regulating epithelial tubulogenesis
    • Rodriguez-Fraticelli A.E., Galvez-Santisteban M., Martin-Belmonte F. Divide and polarize: recent advances in the molecular mechanism regulating epithelial tubulogenesis. Curr Opin Cell Biol 2011, 23:638-646.
    • (2011) Curr Opin Cell Biol , vol.23 , pp. 638-646
    • Rodriguez-Fraticelli, A.E.1    Galvez-Santisteban, M.2    Martin-Belmonte, F.3
  • 35
    • 48249119533 scopus 로고    scopus 로고
    • Phosphatidylinositol 4,5-bisphosphate regulates SNARE-dependent membrane fusion
    • James D.J., Khodthong C., Kowalchyk J.A., Martin T.F. Phosphatidylinositol 4,5-bisphosphate regulates SNARE-dependent membrane fusion. J Cell Biol 2008, 182:355-366.
    • (2008) J Cell Biol , vol.182 , pp. 355-366
    • James, D.J.1    Khodthong, C.2    Kowalchyk, J.A.3    Martin, T.F.4
  • 36
    • 33846354556 scopus 로고    scopus 로고
    • Phosphoinositides specify polarity during epithelial organ development
    • Comer F.I., Parent C.A. Phosphoinositides specify polarity during epithelial organ development. Cell 2007, 128:239-240.
    • (2007) Cell , vol.128 , pp. 239-240
    • Comer, F.I.1    Parent, C.A.2


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