Enhancement of the Promiscuous Aldolase and Dehydration Activities of 4-Oxalocrotonate Tautomerase by Protein Engineering

ChemBioChem

Volumn 13, Issue 9, 2012, Pages 1274-1277

  Zandvoort, Ellen ^a   Geertsema, Edzard M ^a   Quax, Wim J ^a   Poelarends, Gerrit J ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Aldol reaction; Catalytic promiscuity; Enzyme catalysis; Protein engineering; Tautomerases

Indexed keywords

4 OXALOCROTONATE TAUTOMERASE; ACETALDEHYDE; BENZALDEHYDE; ENZYME; FRUCTOSE BISPHOSPHATE ALDOLASE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; CATALYSIS; ELECTROPHILICITY; ENZYME ACTIVITY; ENZYME KINETICS; NUCLEOPHILICITY; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTON NUCLEAR MAGNETIC RESONANCE; ULTRAVIOLET RADIATION; ULTRAVIOLET SPECTROSCOPY;

BIOCATALYSIS; FRUCTOSE-BISPHOSPHATE ALDOLASE; ISOMERASES; KINETICS; PROTEIN ENGINEERING; SUBSTRATE SPECIFICITY; WATER;

EID: 84862492480     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201200225     Document Type: Article

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