메뉴 건너뛰기




Volumn 342, Issue 1, 2012, Pages 2-8

Revisiting the isobole and related quantitative methods for assessing drug synergism

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

EID: 84862488682     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.193474     Document Type: Review
Times cited : (110)

References (40)
  • 1
    • 0027819712 scopus 로고
    • Isobolographic superadditivity between delta and mu opioid agonists in the rat depends on the ratio of compounds, the mu agonist and the analgesic assay used
    • Adams JU, Tallarida RJ, Geller EB, and Adler MW (1993) Isobolographic superadditivity between δ and μ opioid agonists in the rat depends on the ratio of compounds, the μ agonist and the analgesic assay used. J Pharmacol Exp Ther 266:1261-1267. (Pubitemid 24175767)
    • (1993) Journal of Pharmacology and Experimental Therapeutics , vol.266 , Issue.3 , pp. 1261-1267
    • Adams, J.U.1    Tallarida, R.J.2    Geller, E.B.3    Adler, M.W.4
  • 3
    • 0024847290 scopus 로고
    • What is synergy?
    • Berenbaum MC (1989) What is synergy? Pharmacol Rev 41:93-141.
    • (1989) Pharmacol Rev , vol.41 , pp. 93-141
    • Berenbaum, M.C.1
  • 4
    • 84946384873 scopus 로고
    • The toxicity of poisons applied jointly
    • Bliss CI (1939) The toxicity of poisons applied jointly. Ann Appl Biol 26:585-615.
    • (1939) Ann Appl Biol , vol.26 , pp. 585-615
    • Bliss, C.I.1
  • 5
    • 78651508526 scopus 로고    scopus 로고
    • Midazolam enhances the analgesic properties of dexmedetomidine in the rat
    • Boehm, CA, Carney EL, Tallarida RJ, and Wilson RP (2010) Midazolam enhances the analgesic properties of dexmedetomidine in the rat. Vet Anesth Analg 37:550-556.
    • (2010) Vet Anesth Analg , vol.37 , pp. 550-556
    • Boehm, C.A.1    Carney, E.L.2    Tallarida, R.J.3    Wilson, R.P.4
  • 6
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • Chou TC (2006) Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 58:621-681.
    • (2006) Pharmacol Rev , vol.58 , pp. 621-681
    • Chou, T.C.1
  • 7
    • 79959981723 scopus 로고    scopus 로고
    • Synergistic antihypersensitive effects of pregabalin and tapentadol in a rat model of neuropathic pain
    • Christoph T, De Vry J, Schiene K, Tallarida RJ, and Tzschentke TM (2011) Synergistic antihypersensitive effects of pregabalin and tapentadol in a rat model of neuropathic pain. Eur J Pharmacol 666:72-79.
    • (2011) Eur J Pharmacol , vol.666 , pp. 72-79
    • Christoph, T.1    De Vry, J.2    Schiene, K.3    Tallarida, R.J.4    Tzschentke, T.M.5
  • 8
    • 37849031855 scopus 로고    scopus 로고
    • Tramadol and several anticonvulsants synergize in attenuating nerve injury-induced allodynia
    • Codd EE, Martinez RP, Molino L, Rogers KE, Stone DJ, and Tallarida RJ (2008) Tramadol and several anticonvulsants synergize in attenuating nerve injury-induced allodynia. Pain 134:254-262.
    • (2008) Pain , vol.134 , pp. 254-262
    • Codd, E.E.1    Martinez, R.P.2    Molino, L.3    Rogers, K.E.4    Stone, D.J.5    Tallarida, R.J.6
  • 9
    • 0033015422 scopus 로고    scopus 로고
    • Spinal antinociceptive synergism between morphine and clonidine persists in mice made acutely or chronically tolerant to morphine
    • Fairbanks CA and Wilcox GL (1999) Spinal antinociceptive synergism between morphine and clonidine persists in mice made acutely or chronically tolerant to morphine. J Pharmacol Exp Ther 288:1107-1116. (Pubitemid 29254148)
    • (1999) Journal of Pharmacology and Experimental Therapeutics , vol.288 , Issue.3 , pp. 1107-1116
    • Fairbanks, C.A.1    Wilcox, G.L.2
  • 10
    • 0014836064 scopus 로고
    • A study of the interaction hypnotic effects and of the toxic effects of chloral hydrate and ethanol
    • Gessner PK and Cabana BE (1970) A study of the interaction hypnotic effects and of the toxic effects of chloral hydrate and ethanol. J Pharmacol Exp Ther 174:247-259.
    • (1970) J Pharmacol Exp Ther , vol.174 , pp. 247-259
    • Gessner, P.K.1    Cabana, B.E.2
  • 11
    • 4243191446 scopus 로고    scopus 로고
    • Isobolographic analysis for combinations of a full and partial agonist: Curved isoboles
    • DOI 10.1124/jpet.104.067264
    • Grabovsky Y and Tallarida RJ (2004) Isobolographic analysis for combinations of a full and partial agonist: curved isoboles. J Pharmacol Exp Ther 310:981-986. (Pubitemid 39108918)
    • (2004) Journal of Pharmacology and Experimental Therapeutics , vol.310 , Issue.3 , pp. 981-986
    • Grabovsky, Y.1    Tallarida, R.J.2
  • 12
    • 84872220412 scopus 로고    scopus 로고
    • Characterization of the interaction between supraspinal and spinal δ-1 and δ-2 opioid receptors in the production of antinociception in the rat
    • Society for Neuroscience, Washington, DC
    • Hammond DL, Hurley RW, Glabow TS, and Tallarida RJ (1998) Characterization of the interaction between supraspinal and spinal δ-1 and δ-2 opioid receptors in the production of antinociception in the rat. Society for Neuroscience 28th Annual Meeting; 1998 Nov 7-12; Los Angeles, CA. Society for Neuroscience, Washington, DC.
    • (1998) Society for Neuroscience 28th Annual Meeting; 1998 Nov 7-12; Los Angeles, CA
    • Hammond, D.L.1    Hurley, R.W.2    Glabow, T.S.3    Tallarida, R.J.4
  • 13
    • 79957563746 scopus 로고    scopus 로고
    • Resveratrol in combination with other dietary polyphenols concomitantly enhances antiproliferation and UGT1A1 induction in Caco-2 cells
    • Iwuchukwu OF, Tallarida RJ, and Nagar S (2011) Resveratrol in combination with other dietary polyphenols concomitantly enhances antiproliferation and UGT1A1 induction in Caco-2 cells. Life Sci 88:1047-1054.
    • (2011) Life Sci , vol.88 , pp. 1047-1054
    • Iwuchukwu, O.F.1    Tallarida, R.J.2    Nagar, S.3
  • 14
    • 0030819273 scopus 로고    scopus 로고
    • Synergism between buprenorphine and cocaine on the rotational behavior of the nigrally-lesioned rat
    • DOI 10.1007/s002130050416
    • Kimmel HL, Tallarida RJ, and Holtzman SG (1997) Synergism between buprenorphine and cocaine on the rotational behavior of the nigrally-lesioned rat. Psychopharmacology 133:372-377. (Pubitemid 27462811)
    • (1997) Psychopharmacology , vol.133 , Issue.4 , pp. 372-377
    • Kimmel, H.L.1    Tallarida, R.J.2    Holtzman, S.G.3
  • 15
    • 80054755338 scopus 로고    scopus 로고
    • On the quantitation of an agonist with dual but opposing components of action: Application to vascular endothelial relaxation
    • Lamarre NS, Parry T, and Tallarida RJ (2011) On the quantitation of an agonist with dual but opposing components of action: application to vascular endothelial relaxation. Eur J Pharmacol 670:204-207.
    • (2011) Eur J Pharmacol , vol.670 , pp. 204-207
    • Lamarre, N.S.1    Parry, T.2    Tallarida, R.J.3
  • 16
    • 43549109808 scopus 로고    scopus 로고
    • A quantitative study to assess synergistic interactions between urotensin II and angiotensin II
    • Lamarre NS and Tallarida RJ (2008) A quantitative study to assess synergistic interactions between urotensin II and angiotensin II. Eur J Pharmacol 586:350-351.
    • (2008) Eur J Pharmacol , vol.586 , pp. 350-351
    • Lamarre, N.S.1    Tallarida, R.J.2
  • 17
    • 0000419454 scopus 로고
    • Die mischiarnei
    • Loewe S (1927) Die mischiarnei. Klin Wochenschr 6:1077-1085.
    • (1927) Klin Wochenschr , vol.6 , pp. 1077-1085
    • Loewe, S.1
  • 18
    • 0001935126 scopus 로고
    • Die quantitativen probleme der pharmakologie
    • Loewe S (1928) Die quantitativen probleme der pharmakologie. Ergebn Physiol 27:47-187.
    • (1928) Ergebn Physiol , vol.27 , pp. 47-187
    • Loewe, S.1
  • 19
    • 0001663843 scopus 로고
    • The problem of synergism and antagonism of combined drugs
    • Loewe S (1953) The problem of synergism and antagonism of combined drugs. Arzneimittelforschung 3:285-290.
    • (1953) Arzneimittelforschung , vol.3 , pp. 285-290
    • Loewe, S.1
  • 20
    • 0025695013 scopus 로고
    • An isobolographic analysis of the antinociceptive effect of systemically and intrathecally administered combinations of clonidine and opiates
    • Ossipov MH, Harris S, Lloyd P, and Messineo E (1990) An isobolographic analysis of the antinociceptive effect of systemically and intrathecally administered combinations of clonidine and opiates. J Pharmacol Exp Ther 255:1107-1116.
    • (1990) J Pharmacol Exp Ther , vol.255 , pp. 1107-1116
    • Ossipov, M.H.1    Harris, S.2    Lloyd, P.3    Messineo, E.4
  • 21
    • 80051629593 scopus 로고    scopus 로고
    • Combination drugs-hype, harm, and hope
    • Podolsky SH and Greene JA (2011) Combination drugs-hype, harm, and hope. N Engl J Med 365:488-491.
    • (2011) N Engl J Med , vol.365 , pp. 488-491
    • Podolsky, S.H.1    Greene, J.A.2
  • 22
    • 0025216638 scopus 로고
    • 5]enkephalin: A synergistic interaction
    • Porreca F, Jiang Q, and Tallarida RJ (1990) Modulation of morphine antinociception by peripheral [Leu5]-enkephalin: a synergistic interaction. Eur J Pharmacol 179:463-468. (Pubitemid 20137518)
    • (1990) European Journal of Pharmacology , vol.179 , Issue.3 , pp. 463-468
    • Porreca, F.1    Jiang, Q.2    Tallarida, R.J.3
  • 24
    • 84862497510 scopus 로고
    • Composition comprising a tramadol material and acetaminophen and its use
    • inventors; McNeilab, Inc., assignee. U.S. patent 5,336,691. 1994 Aug 9
    • Raffa RB and Vaught JL (1992) inventors; McNeilab, Inc., assignee. Composition comprising a tramadol material and acetaminophen and its use. U.S. patent 5,336,691. 1994 Aug 9.
    • (1992)
    • Raffa, R.B.1    Vaught, J.L.2
  • 25
    • 0036784507 scopus 로고    scopus 로고
    • N-methyl-Daspartate antagonists and WIN 55212-2 [4,5-dihydro-2-methyl- 4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6H-pyrrolo[3,2,1-i,j] quinolin-6-one], a cannabinoid agonist, interact to produce synergistic hypothermia
    • Rawls SM, Cowan A, Tallarida RJ, Geller EB, and Adler MW (2002) N-methyl-Daspartate antagonists and WIN 55212-2 [4,5-dihydro-2-methyl-4(4- morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6H-pyrrolo[3,2,1-i,j] quinolin-6-one], a cannabinoid agonist, interact to produce synergistic hypothermia. J Pharmacol Exp Ther 303:395-402.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 395-402
    • Rawls, S.M.1    Cowan, A.2    Tallarida, R.J.3    Geller, E.B.4    Adler, M.W.5
  • 28
    • 0036299135 scopus 로고    scopus 로고
    • The interaction index: A measure of drug synergism
    • Tallarida RJ (2002) The interaction index: a measure of drug synergism. Pain 98:163-168.
    • (2002) Pain , vol.98 , pp. 163-168
    • Tallarida, R.J.1
  • 29
    • 33749007441 scopus 로고    scopus 로고
    • An overview of drug combination analysis with isobolograms
    • Tallarida RJ (2006) An overview of drug combination analysis with isobolograms. J Pharmacol Exp Ther 319:1-7.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 1-7
    • Tallarida, R.J.1
  • 30
    • 33845716253 scopus 로고    scopus 로고
    • Interactions between drugs and occupied receptors
    • Tallarida RJ (2007) Interactions between drugs and occupied receptors. Pharmacol Ther 113:197-209.
    • (2007) Pharmacol Ther , vol.113 , pp. 197-209
    • Tallarida, R.J.1
  • 31
    • 0142148145 scopus 로고    scopus 로고
    • Antinociceptive Synergy, Additivity, and Subadditivity with Combinations of Oral Glucosamine Plus Nonopioid Analgesics in Mice
    • DOI 10.1124/jpet.103.054320
    • Tallarida RJ, Cowan A, and Raffa RB (2003) Antinociceptive synergy, additivity, and subadditivity with combinations of oral glucosamine plus nonopioid analgesics in mice. J. Pharmacol Exp Ther 307:699-704. (Pubitemid 37310686)
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.307 , Issue.2 , pp. 699-704
    • Tallarida, R.J.1    Cowan, A.2    Raffa, R.B.3
  • 32
    • 77953027819 scopus 로고    scopus 로고
    • On deriving the dose-effect relation of an unknown second component: An example using buprenorphine preclinical data
    • Tallarida RJ, Cowan A, and Raffa RB (2010) On deriving the dose-effect relation of an unknown second component: an example using buprenorphine preclinical data. Drug Alcohol Depend 109:126-129.
    • (2010) Drug Alcohol Depend , vol.109 , pp. 126-129
    • Tallarida, R.J.1    Cowan, A.2    Raffa, R.B.3
  • 33
  • 34
    • 0030026024 scopus 로고    scopus 로고
    • Testing for synergism over a range of fixed ratio drug combinations: Replacing the isobologram
    • Tallarida RJ and Raffa RB (1996) Testing for synergism over a range of fixed ratio drug combinations: replacing the isobologram. Life Sci 58:PL 23-28.
    • (1996) Life Sci , vol.58
    • Tallarida, R.J.1    Raffa, R.B.2
  • 35
    • 77954216658 scopus 로고    scopus 로고
    • The application of drug dose equivalence in the quantitative analysis of receptor occupation and drug combinations
    • Tallarida RJ and Raffa RB (2010) The application of drug dose equivalence in the quantitative analysis of receptor occupation and drug combinations. Pharmacol Ther 127:165-174.
    • (2010) Pharmacol Ther , vol.127 , pp. 165-174
    • Tallarida, R.J.1    Raffa, R.B.2
  • 38
    • 0023096148 scopus 로고
    • Mutual potentiation of antinociceptive effects of morphine and clonidine on motor and sensory responses in rat spinal cord
    • DOI 10.1016/0006-8993(87)90992-9
    • Wilcox GL, Carlsson KH, Jochim A, and Jurna I (1987) Mutual potentiation of antinociceptive effects of morphine and clonidine on motor and sensory responses in rat spinal cord. Brain Res 405:84-93. (Pubitemid 17034935)
    • (1987) Brain Research , vol.405 , Issue.1 , pp. 84-93
    • Wilcox, G.L.1    Carlsson, K.-H.2    Jochim, A.3    Jurna, I.4
  • 39
    • 43049122775 scopus 로고    scopus 로고
    • Self-administration of drug mixtures by monkeys: Combining drugs with comparable mechanisms of action
    • Woolverton WL, Wang Z, Vasterling T, Carroll FI, and Tallarida R (2008a) Self-administration of drug mixtures by monkeys: combining drugs with comparable mechanisms of action. Psychopharmacology 196:575-582.
    • (2008) Psychopharmacology , vol.196 , pp. 575-582
    • Woolverton, W.L.1    Wang, Z.2    Vasterling, T.3    Carroll, F.I.4    Tallarida, R.5
  • 40
    • 44249121445 scopus 로고    scopus 로고
    • Self-administration of cocaine-remifentanil mixtures by monkeys: An isobolographic analysis
    • Woolverton WL, Wang Z, Vasterling T, and Tallarida R (2008b) Self-administration of cocaine-remifentanil mixtures by monkeys: an isobolographic analysis. Psychopharmacology 198:387-394.
    • (2008) Psychopharmacology , vol.198 , pp. 387-394
    • Woolverton, W.L.1    Wang, Z.2    Vasterling, T.3    Tallarida, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.