On deriving the dose-effect relation of an unknown second component: An example using buprenorphine preclinical data

Drug and Alcohol Dependence

Volumn 109, Issue 1-3, 2010, Pages 126-129

  Tallarida, Ronald J ^a   Cowan, Alan ^a   Raffa, Robert B ^b  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF PHARMACY   (United States)

Author keywords

Addiction; Analgesia; Biphasic dose response curve; Buprenorphine; Hormesis; Isobolographic analysis

Indexed keywords

BUPRENORPHINE; NOCICEPTIN;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; HORMESIS; LOW DRUG DOSE; MOUSE; NONHUMAN; OPIATE ADDICTION; PAIN; PRIORITY JOURNAL; RAT; RESPONSE TIME; TAIL FLICK TEST;

ALGORITHMS; ANALGESICS, OPIOID; ANIMALS; BUPRENORPHINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; IMMERSION; INJECTIONS, SUBCUTANEOUS; MICE; NARCOTIC ANTAGONISTS; PAIN MEASUREMENT; RATS; SPECIES SPECIFICITY;

RATTUS;

EID: 77953027819     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2009.12.014     Document Type: Article

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